Development and optimization of analitical methodology to evaluate oleic acid, ethanolamine, pharmaceuticals used for the manufacturing of triethanolamine oleate injection
In this paper we present the results obtained during standarization of the separation systems for the assement of oleic acid and ethanolamine, pharmaceuticals used for the manufacturing of triethanolamine oleate injection BP. For the HPLC assay of oleic acid we used a Free Fatty Acids Waters® column...
- Autores:
-
Sierra, Noralba
Bolivar, Andrea Cristina
Rojas, Jaime
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 1999
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/23771
- Acceso en línea:
- https://repositorio.unal.edu.co/handle/unal/23771
http://bdigital.unal.edu.co/14808/
- Palabra clave:
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
| Summary: | In this paper we present the results obtained during standarization of the separation systems for the assement of oleic acid and ethanolamine, pharmaceuticals used for the manufacturing of triethanolamine oleate injection BP. For the HPLC assay of oleic acid we used a Free Fatty Acids Waters® column and acetonitrile – water (46 : 54) as mobile phase; the detection was performed at 201nm. Finally, a SE-30 glass column and a flame ionization detector (FID) was used for the gas chromatographic assay of ethanolamine. |
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