Validation of a uv spectrophotometric and a reverse high performance methods for the assay of codeine phosphate in tablets
In this paper we present the results obtained during the validation of a UV spectrometric meted for the assay of codeine phosphate in tablets and in uniformity of content test. Also we report the results obtained in the validation of a reverse high performance method developed for the determination...
- Autores:
-
Romero, Diego
Gil, Andrés
Rojas, Jaime
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2000
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/23760
- Acceso en línea:
- https://repositorio.unal.edu.co/handle/unal/23760
http://bdigital.unal.edu.co/14797/
- Palabra clave:
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
| Summary: | In this paper we present the results obtained during the validation of a UV spectrometric meted for the assay of codeine phosphate in tablets and in uniformity of content test. Also we report the results obtained in the validation of a reverse high performance method developed for the determination of codeine phosphate in the dissolution test and in the quality control with release purpose. As stationary bounded phase we used octadecylsilane and a mobile phase composed of acetonitrile-water-triethylamine (4,0: 95,9 : 0,1). The detection was performed at 230 nm. |
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