Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos
ilustraciones, diagramas, fotografías
- Autores:
-
Camacho Vargas, Sazi Alberto
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2023
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/86400
- Palabra clave:
- 590 - Animales::599 - Mamíferos
Mastocitoma Cutáneo/diagnóstico
Sarcoma/diagnóstico
Protocolos Clínicos
Mastocytoma, Skin/diagnosis
Sarcoma/diagnosis
Clinical Protocols
Neoplasia
Mastocitoma
Sarcoma de tejidos blandos
Mast cell tumor
Neoplasia
Soft tissue sarcoma
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional
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Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos |
| dc.title.translated.eng.fl_str_mv |
Reparation of protocols for the histopathological evaluation of mast cell tumor and soft tissue sarcomas in canines |
| title |
Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos |
| spellingShingle |
Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos 590 - Animales::599 - Mamíferos Mastocitoma Cutáneo/diagnóstico Sarcoma/diagnóstico Protocolos Clínicos Mastocytoma, Skin/diagnosis Sarcoma/diagnosis Clinical Protocols Neoplasia Mastocitoma Sarcoma de tejidos blandos Mast cell tumor Neoplasia Soft tissue sarcoma |
| title_short |
Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos |
| title_full |
Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos |
| title_fullStr |
Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos |
| title_full_unstemmed |
Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos |
| title_sort |
Elaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninos |
| dc.creator.fl_str_mv |
Camacho Vargas, Sazi Alberto |
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Botero Espinosa, Lucía |
| dc.contributor.author.spa.fl_str_mv |
Camacho Vargas, Sazi Alberto |
| dc.subject.ddc.spa.fl_str_mv |
590 - Animales::599 - Mamíferos |
| topic |
590 - Animales::599 - Mamíferos Mastocitoma Cutáneo/diagnóstico Sarcoma/diagnóstico Protocolos Clínicos Mastocytoma, Skin/diagnosis Sarcoma/diagnosis Clinical Protocols Neoplasia Mastocitoma Sarcoma de tejidos blandos Mast cell tumor Neoplasia Soft tissue sarcoma |
| dc.subject.decs.spa.fl_str_mv |
Mastocitoma Cutáneo/diagnóstico Sarcoma/diagnóstico Protocolos Clínicos |
| dc.subject.decs.eng.fl_str_mv |
Mastocytoma, Skin/diagnosis Sarcoma/diagnosis Clinical Protocols |
| dc.subject.proposal.spa.fl_str_mv |
Neoplasia Mastocitoma Sarcoma de tejidos blandos |
| dc.subject.proposal.eng.fl_str_mv |
Mast cell tumor Neoplasia Soft tissue sarcoma |
| description |
ilustraciones, diagramas, fotografías |
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2023 |
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2023-11-08 |
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2024-07-05T12:59:49Z |
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2024-07-05T12:59:49Z |
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Trabajo de grado - Especialización |
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info:eu-repo/semantics/bachelorThesis |
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Universidad Nacional de Colombia |
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Repositorio Institucional Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/ |
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Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
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spa |
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Avallone, G., Helmbold, P, Caniatti, M, Stefanello, D, Nayak, R C, & Roccabianca, P (2007). The Spectrum of Canine Cutaneous Perivascular Wall Tumors: Morphologic, Phenotypic and Clinical Characterization. Veterinary Pathology, 44(5), 607–620. Avallone, G., Rasotto, R., Chambers, J. K., Miller, A. D., Behling-Kelly, E., Monti, P., … Roccabianca, P. (2021). Review of Histological Grading Systems in Veterinary Medicine. Veterinary Pathology, 58(5), 809–828.Dei Tos, A (2018). Introduction. In A. Dei Tos (Author), Soft Tissue Sarcomas: A Pattern-Based Approach to Diagnosis (pp. 1-32). Cambridge: Cambridge University Press. Cannas J. P. & Shonning P. (1994) Canine mast cell tumors: a comparison of staining techniques. J Vet Diagn Invest 6:458-465. Dei Tos, A (2018). Introduction. In A. Dei Tos (Author), Soft Tissue Sarcomas: A Pattern-Based Approach to Diagnosis (pp. 1-32). Cambridge: Cambridge University Press. Del Alcazar, C M, Mahoney, J A, Dittrich, K, Stefanovski, D, & Church, M E (2021). Outcome, prognostic factors and histological characterization of canine gastrointestinal sarcomas. Veterinary and Comparative Oncology, 19(3), 578–586. Dennis, M M, McSporran, K D, Bacon, N J, Schulman, F Y, Foster, R A, & Powers, B E (2010). Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs. Veterinary Pathology, 48(1), 73–84. Jakab, C, Gálfi, P, Jerzsele, Á, Szabó, Z, Németh, T, Sterczer, Á, Rusvai, M, & Ózsvári, L (2012). Expression of claudin-1 in canine peripheral nerve sheath tumours and perivascular wall tumours. Immunohistochemical study. Histology and histopathology, 27(7), 905–917. Kamstock, D A, Ehrhart, E J, Getzy, D M, Bacon, N J, Rassnick, K M, Moroff, S D, Kiupel, M (2010). Recommended Guidelines for Submission, Trimming, Margin Evaluation, and Reporting of Tumor Biopsy Specimens in Veterinary Surgical Pathology. Veterinary Pathology, 48(1), 19–31. Kiupel, M, Webster, J D, Bailey, K L, Best, S, DeLay, J, Detrisac, C J, Miller, R (2010). Proposal of a 2-Tier Histologic Grading System for Canine Cutaneous Mast Cell Tumors to More Accurately Predict Biological Behavior. Veterinary Pathology, 48(1), 147–155. Meuten, D J, Moore, F M, Donovan, T A, Bertram, C A, Klopfleisch, R, Foster, R A, Whitley, D (2021). International Guidelines for Veterinary Tumor Pathology: A Call to Action. Veterinary Pathology, 58(5), 766–794. Patnaik, A. K., Ehler, W. J., & MacEwen, E. G. (1984). Canine cutaneous mast cell tumor: morphologic grading and survival time in 83 dogs. Veterinary pathology, 21(5), 469–474. Strefezzi, Ricardo & Kleeb, Silvia & Xavier, J.G. & Catão-Dias, José. (2009). Prognostic indicators for mast cell tumors. Braz J Vet Pathol Brazilian Journal of Veterinary Pathology. 2. 110-121. Webster, J D, Yuzbasiyan-Gurkan, V, Miller, R A, Kaneene, J B, & Kiupel, M (2007). Cellular Proliferation in Canine Cutaneous Mast Cell Tumors: Associations with c-KIT and Its Role in Prognostication. Veterinary Pathology, 44(3), 298–308. Wippold, F J, Lubner, M, Perrin, R J, Lammle, M, & Perry, A (2007). Neuropathology for the Neuroradiologist: Antoni A and Antoni B Tissue Patterns. American Journal of Neuroradiology, 28(9), 1633–1638. |
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Universidad Nacional de Colombia |
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Bogotá - Medicina Veterinaria y de Zootecnia - Especialidad en Anatomopatología Veterinaria |
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Facultad de Medicina Veterinaria y de Zootecnia |
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Bogotá, Colombia |
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Universidad Nacional de Colombia - Sede Bogotá |
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Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Botero Espinosa, Lucía2708e5b88997141c20524d894c6027bfCamacho Vargas, Sazi Alberto21c10d9eb323d9d7f7aa4dcc2df3ecbd2024-07-05T12:59:49Z2024-07-05T12:59:49Z2023-11-08https://repositorio.unal.edu.co/handle/unal/86400Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramas, fotografíasEn estudios de oncología humana se han realizado diversos estudios que enfocados en reducir la variación entre patólogos en estudios interobservadores al momento de evaluar neoplasias, para reducir la subjetividad y generar resultados que logren ser reproducidos en diferentes estudios y correlacionarse con la clínica del paciente; sin embargo, en medicina veterinaria, son pocos los estudios que proponen protocolos para la evaluación de neoplasias, que puedan relacionarse con el pronóstico de los pacientes. Entre estos tumores se encuentran el Mastocitoma canino, así como el sarcoma de tejidos blandos. Este trabajo tiene como objetivo proponer protocolos de evaluación para aportar a la estandarización macroscópica y microscópica de evaluación de tumores en caninos, realizando una revisión de literatura sobre las diferentes técnicas de corte macroscópico de tejidos de masas cutáneas y subcutáneas, así como de mastocitoma canino cutáneo y subcutáneo, y de sarcoma de tejidos blandos; entre los diferentes aspectos evaluados, se encuentran características morfológicas las cuales se evalúan por tinción de rutina de hematoxilina-eosina, y algunas características son evaluadas por medio de tinciones inmunohistoquímicas con fines tanto diagnósticos (principalmente para sarcomas de tejidos blandos), como pronósticos. Posteriormente se realiza una propuesta de protocolos basados en la revisión de literatura, para cortes macroscópicos de masas cutáneas y subcutáneas, evaluación diagnostica y pronostica de Mastocitoma cutáneo, y evaluación diagnóstica de sarcomas de tejidos blandos en caninos. (Texto tomado de la fuente).In human oncology studies, various studies have been carried out that focus on reducing the variation between pathologists in interobserver studies when evaluating neoplasms, to reduce subjectivity and generate results that can be reproduced in different studies and correlated with the patient's clinical features; However, in veterinary medicine, there are few studies that propose protocols for the evaluation of neoplasms that can be related to the prognosis of patients. These tumors include canine mast cell tumors, as well as soft tissue sarcoma. This work aims to propose evaluation protocols to contribute to the macroscopic and microscopic standardization of tumor evaluation in canines, conducting a literature review on the different techniques for gross trimming of cutaneous and subcutaneous tumors, as well as cutaneous canine mast cell tumors. and subcutaneous, and soft tissue sarcoma; Among the different aspects evaluated, there are morphological characteristics which are evaluated by routine hematoxylin-eosin staining, and some characteristics are evaluated by means of immunohistochemical stains for both diagnostic (mainly for soft tissue sarcomas) and prognostic purposes. Subsequently, a protocol proposal is made based on the literature review, for gross trimming cutaneous and subcutaneous tumors, diagnostic and prognostic evaluation of cutaneous mast cell tumors, and diagnostic evaluation of soft tissue sarcomas in canines.Especialidades MédicasEspecialista en Anatomopatología Veterinariaxii, 36 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina Veterinaria y de Zootecnia - Especialidad en Anatomopatología VeterinariaFacultad de Medicina Veterinaria y de ZootecniaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá590 - Animales::599 - MamíferosMastocitoma Cutáneo/diagnósticoSarcoma/diagnósticoProtocolos ClínicosMastocytoma, Skin/diagnosisSarcoma/diagnosisClinical ProtocolsNeoplasiaMastocitomaSarcoma de tejidos blandosMast cell tumorNeoplasiaSoft tissue sarcomaElaboración de protocolos de evaluación histopatológica de mastocitoma y sarcomas de tejidos blandos en caninosReparation of protocols for the histopathological evaluation of mast cell tumor and soft tissue sarcomas in caninesTrabajo de grado - Especializacióninfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_7a1fTexthttp://purl.org/redcol/resource_type/TPAvallone, G., Helmbold, P, Caniatti, M, Stefanello, D, Nayak, R C, & Roccabianca, P (2007). The Spectrum of Canine Cutaneous Perivascular Wall Tumors: Morphologic, Phenotypic and Clinical Characterization. Veterinary Pathology, 44(5), 607–620.Avallone, G., Rasotto, R., Chambers, J. K., Miller, A. D., Behling-Kelly, E., Monti, P., … Roccabianca, P. (2021). Review of Histological Grading Systems in Veterinary Medicine. Veterinary Pathology, 58(5), 809–828.Dei Tos, A (2018). Introduction. In A. Dei Tos (Author), Soft Tissue Sarcomas: A Pattern-Based Approach to Diagnosis (pp. 1-32). Cambridge: Cambridge University Press.Cannas J. P. & Shonning P. (1994) Canine mast cell tumors: a comparison of staining techniques. J Vet Diagn Invest 6:458-465.Dei Tos, A (2018). Introduction. In A. Dei Tos (Author), Soft Tissue Sarcomas: A Pattern-Based Approach to Diagnosis (pp. 1-32). Cambridge: Cambridge University Press.Del Alcazar, C M, Mahoney, J A, Dittrich, K, Stefanovski, D, & Church, M E (2021). Outcome, prognostic factors and histological characterization of canine gastrointestinal sarcomas. Veterinary and Comparative Oncology, 19(3), 578–586.Dennis, M M, McSporran, K D, Bacon, N J, Schulman, F Y, Foster, R A, & Powers, B E (2010). Prognostic Factors for Cutaneous and Subcutaneous Soft Tissue Sarcomas in Dogs. Veterinary Pathology, 48(1), 73–84.Jakab, C, Gálfi, P, Jerzsele, Á, Szabó, Z, Németh, T, Sterczer, Á, Rusvai, M, & Ózsvári, L (2012). Expression of claudin-1 in canine peripheral nerve sheath tumours and perivascular wall tumours. Immunohistochemical study. Histology and histopathology, 27(7), 905–917.Kamstock, D A, Ehrhart, E J, Getzy, D M, Bacon, N J, Rassnick, K M, Moroff, S D, Kiupel, M (2010). Recommended Guidelines for Submission, Trimming, Margin Evaluation, and Reporting of Tumor Biopsy Specimens in Veterinary Surgical Pathology. Veterinary Pathology, 48(1), 19–31.Kiupel, M, Webster, J D, Bailey, K L, Best, S, DeLay, J, Detrisac, C J, Miller, R (2010). Proposal of a 2-Tier Histologic Grading System for Canine Cutaneous Mast Cell Tumors to More Accurately Predict Biological Behavior. Veterinary Pathology, 48(1), 147–155.Meuten, D J, Moore, F M, Donovan, T A, Bertram, C A, Klopfleisch, R, Foster, R A, Whitley, D (2021). International Guidelines for Veterinary Tumor Pathology: A Call to Action. Veterinary Pathology, 58(5), 766–794.Patnaik, A. K., Ehler, W. J., & MacEwen, E. G. (1984). Canine cutaneous mast cell tumor: morphologic grading and survival time in 83 dogs. Veterinary pathology, 21(5), 469–474.Strefezzi, Ricardo & Kleeb, Silvia & Xavier, J.G. & Catão-Dias, José. (2009). Prognostic indicators for mast cell tumors. Braz J Vet Pathol Brazilian Journal of Veterinary Pathology. 2. 110-121.Webster, J D, Yuzbasiyan-Gurkan, V, Miller, R A, Kaneene, J B, & Kiupel, M (2007). Cellular Proliferation in Canine Cutaneous Mast Cell Tumors: Associations with c-KIT and Its Role in Prognostication. Veterinary Pathology, 44(3), 298–308.Wippold, F J, Lubner, M, Perrin, R J, Lammle, M, & Perry, A (2007). Neuropathology for the Neuroradiologist: Antoni A and Antoni B Tissue Patterns. 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