Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021
gráficas, ilustraciones
- Autores:
-
Zamora Becerra, Leidy Vanesa
- Tipo de recurso:
- Fecha de publicación:
- 2021
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/80823
- Palabra clave:
- 610 - Medicina y salud
Fine-needle biopsy
Lymph nodes
Lung neoplasms
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021 |
| dc.title.translated.eng.fl_str_mv |
Identification of the characteristics of the nodules evaluated in the ebus procedure (endobronchial ultrasound) and their relationship with the diagnosis of malignancy in patients of the national institute of cancerology of Colombia between march 31, 2017 and january 31, 2021 |
| title |
Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021 |
| spellingShingle |
Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021 610 - Medicina y salud Fine-needle biopsy Lymph nodes Lung neoplasms |
| title_short |
Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021 |
| title_full |
Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021 |
| title_fullStr |
Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021 |
| title_full_unstemmed |
Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021 |
| title_sort |
Identificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021 |
| dc.creator.fl_str_mv |
Zamora Becerra, Leidy Vanesa |
| dc.contributor.advisor.none.fl_str_mv |
Saavedra Rodríguez, Alfredo |
| dc.contributor.author.none.fl_str_mv |
Zamora Becerra, Leidy Vanesa |
| dc.subject.ddc.spa.fl_str_mv |
610 - Medicina y salud |
| topic |
610 - Medicina y salud Fine-needle biopsy Lymph nodes Lung neoplasms |
| dc.subject.proposal.eng.fl_str_mv |
Fine-needle biopsy Lymph nodes Lung neoplasms |
| description |
gráficas, ilustraciones |
| publishDate |
2021 |
| dc.date.issued.none.fl_str_mv |
2021-01 |
| dc.date.accessioned.none.fl_str_mv |
2022-02-01T01:19:13Z |
| dc.date.available.none.fl_str_mv |
2022-02-01T01:19:13Z |
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Trabajo de grado - Especialidad Médica |
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info:eu-repo/semantics/masterThesis |
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info:eu-repo/semantics/acceptedVersion |
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Text |
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http://purl.org/redcol/resource_type/TM |
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acceptedVersion |
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https://repositorio.unal.edu.co/handle/unal/80823 |
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Universidad Nacional de Colombia |
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Repositorio Institucional Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/ |
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https://repositorio.unal.edu.co/handle/unal/80823 https://repositorio.unal.edu.co/ |
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Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
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spa |
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spa |
| dc.relation.references.spa.fl_str_mv |
American cáncer Society. cáncer Facts & Figures 2013. Atlanta, GA: American cáncer Society; 2013. MINSALUD,. observatorio nacional de cancer. https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/VS/ED/GCFI/guia-ross-cancer.pdf Agarwal R, Srinivasan A, Aggarwal AN, Gupta D. Efficacy and safety of convex probe EBUS-TBNA in sarcoidosis: A systematic review and meta-analysis. Respiratory Medicine (2012) 106, 883e892. doi:10.1016/j.rmed.2012.02.014 Yasufuku K, Pierre A, Darling G, de Perrot M, Waddell T, Johnston M, et al. A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph node staging of lung cancer. The Journal of Thoracic and Cardiovascular Surgery 2011;142(6):1393e400 e1. Holty JE, Kuschner WG, Gould MK. Accuracy of transbronchial needle aspiration for mediastinal staging of non-small cell lung cancer: a meta-analysis. Thorax 2005;60:949e55 Krasnik M, Vilmann P, Larsen SS, Jacobsen GK. Preliminary experience with a new method of endoscopic transbronchial real time ultrasound guided biopsy for diagnosis of mediastinal and hiliar lesions. Thorax 2003;58:1083–1086. Ernst A, Anantham D, Eberhardt R, Krasnik M, Herth FJ. Diagnosis of mediastinal adenopathy-real-time endobronchial ultrasound guided needle aspiration versus mediastinoscopy. J Thorac Oncol 2008; 3: 577–82 Ayub II, Mohan A, Madan K, Hadda V, Jain D, Khilnani GC, Guleria R. Identification of specific EBUS sonographic characteristics for predicting benign mediastinal lymph nodes. Clin Respir J. 2018 Feb;12(2):681-690. doi: 10.1111/crj.12579. Epub 2016 Nov 15. PMID: 27805323. Yasufuku K, Nakajima T, Motoori K, et al. Comparison of endobronchial ultrasound, positron emisión tomography, and CT for lymph node staging of lung cancer. Chest 2006;130:710–8. VanderLaan PA, WNG hh, Majid A, Folch E. Endobronchial ultrasound-guidede transbronchial needle aspiration (EBUS-TBNA): an overview and update for the cutopathologist. cáncer cytopathologu. 2014: 561- 576. DOI: 10.1002/cncy.21431, Rintoul RC, Glover MJ, Jackson C, et al. Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective [published online ahead of print September 24, 2013]. Thorax. 2013. doi: 10.1136/thoraxjnl-2013-204374. Garcia-Olive I, Sanz-Santos J, Andreo F, Monsó E. Application of real-time endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer stagingt. Thoracic cáncer 1 (2010) 23–27 Detterbeck FC, Jantz MA, Wallace M, Vansteenkiste J, Silvestri GA. Invasive mediastinal staging of lung cancer: ACCP evidencebased clinical practice guidelines (2nd edition). Chest. 2007;132: 202S-220S. Leschber G, Sperling D, Klemm W, Merk J. Does videomediastinoscopy improve the results of conventional mediastinoscopy? Eur J Cardiothorac Surg. 2008;33:289-293. Silvestri GA, Gonzalez AV, Jantz MA, et al. Methods for staging non-small cell lung cancer: diagnosis and management of lung cancer, 3rd edition: American College of Chest Physicians evidencebased clinical practice guidelines. Chest. 2013;143:e211S-e250S. Garcia-Olivé I, Valverde Forcada EX, García FA, Sanz-Santos J, Castellà E, Llatjós M, et al. La ultrasonografía endobronquial lineal como instrumento de diagnóstico inicial en el paciente con ocupación mediastínica. Archivos de Bronconeumología. 2009; 45(6): 266-270. DOI: 10.1016/j.arbres.2008.10 Ayub II, Mohan A, Madan K, Hadda V, Jain D, Khilnani GC, Guleria R. Identification of specific EBUS sonographic characteristics for predicting benign mediastinal lymph nodes. Clin Respir J. 2018 Feb;12(2):681-690. doi: 10.1111/crj.12579. Epub 2016 Nov 15. PMID: 27805323. REPÚBLICA DE COLOMBIA MINISTERIO DE SALUD. RESOLUCIÓN No 008430 DE 1993. MINISTERIO DE SALUD 1993. Abedini, A., Razavi, F., Mehravaran, H., Toutkaboni, P., Kashefizadeh, A., Emami, H., Farahani, M., & Kiani, A. (2020). No Title. 35(2), 4–8. https://doi.org/10.5001/omj.2020.30 Fielding, D., & Soc, F. T. (2018). E n d o b ro n c h i a l U l t r a s o u n d - G u i d e d Tr a n s b ro n c h i a l Needle Aspir ation f or D i a g n o s i s a n d St a g i n g o f Lung Cancer. 39, 111–123. https://doi.org/10.1016/j.ccm.2017.11.012 Fujiwara, T., Yasufuku, K., Nakajima, T., Chiyo, M., Yoshida, S., Suzuki, M., Shibuya, K., Hiroshima, K., Nakatani, Y., & Yoshino, I. (2010). The Utility of Sonographic Features Transbronchial Needle Aspiration for Lymph Node Staging in Patients With Lung Cancer A Standard Endobronchial Ultrasound. CHEST, 138(3), 641–647. https://doi.org/10.1378/chest.09-2006 Khalid, U., Akram, M. J., Butt, F. M., Bilal, M., & Khan, F. (2020). Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Of Mediastinal And Hilar Lymph Nodes- Five Years Of Experience At A Cancer Setting Hospital In Pakistan ENDOBRONCHIAL ULTRASOUND GUIDED TRANSBRONCHIAL NEEDLE ASPIRATION OF MEDIASTINAL AND HI. July. Moon, K. M., Choi, C., Ji, W., Lee, J. S., Lee, S. W., Jo, K., Song, J. W., & Lee, J. C. (n.d.). Clinical Characteristics of and Risk Factors for Fever after Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration : A Retrospective Study Involving 6336 Patients. 5–7. Murthi, M., Donna, E., Arias, S., Villamizar, N. R., Nguyen, D. M., & Biomedical, A. F. (2020). Diagnostic Accuracy of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration ( EBUS-TBNA ) in Real Life. 7(April). https://doi.org/10.3389/fmed.2020.00118 Shafiek, H., Fiorentino, F., David, A., Serra, E., Esteban, B., Martinez, R., Angels, M., Moyano, P., Sala, E., Sauleda, J., & Cosío, B. G. (2014). Predicción en tiempo real de la malignidad de ganglios linfáticos mediastínicos mediante ecografía endobronquial. 50(6), 228–234. Yasufuku K , Fujisawa T . Staging and diagnosis of non-small cell lung cancer: invasive modalities . Respirology . 2007; 12( 2): 173- 183. Yang, B. O., Li, F. A. N. G., Shi, W. E., Liu, H. U. I., Sun, S. H., Zhang, G. U., & Jiao, S. H. (2014). Endobronchial ultrasound-guided transbronchial needle biopsy for the diagnosis of intrathoracic lymph node metastases from extrathoracic malignancies : A meta-analysis and. 834–841. https://doi.org/10.1111/resp.12335 Vincent BD , El-Bayoumi E , Hoffman B , et al . Real-time endobronchial ultrasound-guided transbronchial lymph node aspiration . Ann Thorac Surg . 2008 ; 85 ( 1 ): 224 – 230 Herth FJ, Krasnik M, Vilmann P. EBUS-TBNA for the diagnosis and staging of lung cancer. Endoscopy 2006;38(Suppl 1):S101–5. Dong X, Qiu X, Liu Q, et al. Endobronchial ultrasound-guided transbronchial needle aspiration in the mediastinal staging of non-small cell lung cancer: a meta-analysis. Ann Thorac Surg 2013;96(4): 1502–7. Schmid-Bindert G, Jiang H, Kähler G, et al. Predicting malignancy in mediastinal lymph nodes by endobronchial ultrasound: a new ultrasound scoring system. Respirology. 2012;17: 1190–1198. Nakajima T, Anayama T, Shingyoji M, Kimura H, Yoshino I, Yasufuku K. Vascular image patterns of lymph nodes for the prediction of metastatic disease during EBUS-TBNA for mediastinal staging of lung cancer. J Thorac Oncol. 2012;7: 1009–1014. Memoli JS, El-Bayoumi E, Pastis NJ, et al. Using endobronchial ultrasound features to predict lymph node metastasis in patients with lung cancer. Chest. 2011;140: 1550–1556. Jhun BW, Um S-W, Suh GY, et al. Clinical value of endobronchial ultrasound findings for predicting nodal metastasis in patients with suspected lymphadenopathy: a prospective study. J Korean Med Sci. 2014;29(12):1632– 1638 Dhooria S, Agarwal R, Aggarwal AN, Bal A, Gupta N, Gupta D. Differentiating tuberculosis from sarcoidosis by sonographic characteristics of lymph nodes on endobronchial ultrasonography: a study of 165 patients. J Thorac Cardiovasc Surg. 2014;148(2):662–667. Imai N, Imaizumi K, Ando M, et al. Echoic features of lymph nodes with sarcoidosis determined by endobronchial ultrasound. Intern Med. 2013;52(13):1473–1478. Ozgul MA, Cetinkaya E, Kirkil G, et al. Lymph node characteristics of sarcoidosis with endobronchial ultrasound. Endosc Ultrasound. 2014;3(4):232–237 |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional |
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48 páginas |
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Colombia |
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Universidad Nacional de Colombia |
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Bogotá - Medicina - Especialidad en Neumología Clínica |
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Departamento de Medicina Interna |
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Facultad de Medicina |
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Bogotá |
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Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Saavedra Rodríguez, Alfredo75420345eba84ad970e4e300abeaddacZamora Becerra, Leidy Vanesa3961a5b94c36e27eeb42d5339fb4f07e2022-02-01T01:19:13Z2022-02-01T01:19:13Z2021-01https://repositorio.unal.edu.co/handle/unal/80823Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/gráficas, ilustracionesEl EBUS ha sido objeto de múltiples estudios, en búsqueda de evaluar su utilidad y rendimiento diagnostico en diversas patologías, algunos de estos estudios han incluido la evaluación de las características morfológicas de los ganglios y su relación con el diagnostico de malignidad. Se realizó un estudio observacional, analítico de corte transversal, en pacientes mayores de 18 años atendidos en el servicio de neumología del Instituto Nacional de Cancerología entre 1 de enero de 2017 hasta 31 de marzo de 2021, La recolección se realizó por muestreo no probabilístico de casos consecutivos de todos los sujetos que cumplan los criterios de inclusión.Abstract Identification of the characteristics of the lymph nodes evaluated in the EBUS procedure (endobronchial ultrasound) and their relationship with the diagnosis of malignancy in patients from the National Cancer Institute of Colombia between January 1, 2017 and March 31, 2021. EBUS has been the subject of multiple studies, seeking to evaluate its usefulness and diagnostic performance in various pathologies, some of these studies have included the evaluation of the morphological characteristics of the lymph nodes and their relationship with the diagnosis of malignancy. An observational, analytical cross-sectional study was carried out in patients older than 18 years treated in the pulmonology service of the National Cancer Institute between January 1, 2017 and March 31, 2021. The collection was carried out by non-probabilistic sampling of consecutive cases of all subjects meeting the inclusion criteria.Especialidades MédicasEspecialista en Neumología Clínica48 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Especialidad en Neumología ClínicaDepartamento de Medicina InternaFacultad de MedicinaBogotáUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y saludFine-needle biopsyLymph nodesLung neoplasmsIdentificación de las características de los ganglios evaluados en el procedimiento ebus (ultrasonido endobronquial) y su relación con el diagnóstico de malignidad en pacientes del instituto nacional de cancerología de Colombia entre el 1 de enero de 2017 y 31 de marzo de 2021Identification of the characteristics of the nodules evaluated in the ebus procedure (endobronchial ultrasound) and their relationship with the diagnosis of malignancy in patients of the national institute of cancerology of Colombia between march 31, 2017 and january 31, 2021Trabajo de grado - Especialidad Médicainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMColombiaAmerican cáncer Society. cáncer Facts & Figures 2013. Atlanta, GA: American cáncer Society; 2013.MINSALUD,. observatorio nacional de cancer. https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/VS/ED/GCFI/guia-ross-cancer.pdfAgarwal R, Srinivasan A, Aggarwal AN, Gupta D. Efficacy and safety of convex probe EBUS-TBNA in sarcoidosis: A systematic review and meta-analysis. Respiratory Medicine (2012) 106, 883e892. doi:10.1016/j.rmed.2012.02.014Yasufuku K, Pierre A, Darling G, de Perrot M, Waddell T, Johnston M, et al. A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph node staging of lung cancer. The Journal of Thoracic and Cardiovascular Surgery 2011;142(6):1393e400 e1.Holty JE, Kuschner WG, Gould MK. Accuracy of transbronchial needle aspiration for mediastinal staging of non-small cell lung cancer: a meta-analysis. Thorax 2005;60:949e55Krasnik M, Vilmann P, Larsen SS, Jacobsen GK. Preliminary experience with a new method of endoscopic transbronchial real time ultrasound guided biopsy for diagnosis of mediastinal and hiliar lesions. Thorax 2003;58:1083–1086.Ernst A, Anantham D, Eberhardt R, Krasnik M, Herth FJ. Diagnosis of mediastinal adenopathy-real-time endobronchial ultrasound guided needle aspiration versus mediastinoscopy. J Thorac Oncol 2008; 3: 577–82Ayub II, Mohan A, Madan K, Hadda V, Jain D, Khilnani GC, Guleria R. Identification of specific EBUS sonographic characteristics for predicting benign mediastinal lymph nodes. Clin Respir J. 2018 Feb;12(2):681-690. doi: 10.1111/crj.12579. Epub 2016 Nov 15. PMID: 27805323.Yasufuku K, Nakajima T, Motoori K, et al. Comparison of endobronchial ultrasound, positron emisión tomography, and CT for lymph node staging of lung cancer. Chest 2006;130:710–8.VanderLaan PA, WNG hh, Majid A, Folch E. Endobronchial ultrasound-guidede transbronchial needle aspiration (EBUS-TBNA): an overview and update for the cutopathologist. cáncer cytopathologu. 2014: 561- 576. DOI: 10.1002/cncy.21431,Rintoul RC, Glover MJ, Jackson C, et al. Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective [published online ahead of print September 24, 2013]. Thorax. 2013. doi: 10.1136/thoraxjnl-2013-204374.Garcia-Olive I, Sanz-Santos J, Andreo F, Monsó E. Application of real-time endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer stagingt. Thoracic cáncer 1 (2010) 23–27Detterbeck FC, Jantz MA, Wallace M, Vansteenkiste J, Silvestri GA. Invasive mediastinal staging of lung cancer: ACCP evidencebased clinical practice guidelines (2nd edition). Chest. 2007;132: 202S-220S.Leschber G, Sperling D, Klemm W, Merk J. Does videomediastinoscopy improve the results of conventional mediastinoscopy? Eur J Cardiothorac Surg. 2008;33:289-293.Silvestri GA, Gonzalez AV, Jantz MA, et al. Methods for staging non-small cell lung cancer: diagnosis and management of lung cancer, 3rd edition: American College of Chest Physicians evidencebased clinical practice guidelines. Chest. 2013;143:e211S-e250S.Garcia-Olivé I, Valverde Forcada EX, García FA, Sanz-Santos J, Castellà E, Llatjós M, et al. La ultrasonografía endobronquial lineal como instrumento de diagnóstico inicial en el paciente con ocupación mediastínica. Archivos de Bronconeumología. 2009; 45(6): 266-270. DOI: 10.1016/j.arbres.2008.10Ayub II, Mohan A, Madan K, Hadda V, Jain D, Khilnani GC, Guleria R. Identification of specific EBUS sonographic characteristics for predicting benign mediastinal lymph nodes. Clin Respir J. 2018 Feb;12(2):681-690. doi: 10.1111/crj.12579. Epub 2016 Nov 15. PMID: 27805323.REPÚBLICA DE COLOMBIA MINISTERIO DE SALUD. RESOLUCIÓN No 008430 DE 1993. MINISTERIO DE SALUD 1993.Abedini, A., Razavi, F., Mehravaran, H., Toutkaboni, P., Kashefizadeh, A., Emami, H., Farahani, M., & Kiani, A. (2020). No Title. 35(2), 4–8. https://doi.org/10.5001/omj.2020.30Fielding, D., & Soc, F. T. (2018). E n d o b ro n c h i a l U l t r a s o u n d - G u i d e d Tr a n s b ro n c h i a l Needle Aspir ation f or D i a g n o s i s a n d St a g i n g o f Lung Cancer. 39, 111–123. https://doi.org/10.1016/j.ccm.2017.11.012Fujiwara, T., Yasufuku, K., Nakajima, T., Chiyo, M., Yoshida, S., Suzuki, M., Shibuya, K., Hiroshima, K., Nakatani, Y., & Yoshino, I. (2010). The Utility of Sonographic Features Transbronchial Needle Aspiration for Lymph Node Staging in Patients With Lung Cancer A Standard Endobronchial Ultrasound. CHEST, 138(3), 641–647. https://doi.org/10.1378/chest.09-2006Khalid, U., Akram, M. J., Butt, F. M., Bilal, M., & Khan, F. (2020). Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Of Mediastinal And Hilar Lymph Nodes- Five Years Of Experience At A Cancer Setting Hospital In Pakistan ENDOBRONCHIAL ULTRASOUND GUIDED TRANSBRONCHIAL NEEDLE ASPIRATION OF MEDIASTINAL AND HI. July.Moon, K. M., Choi, C., Ji, W., Lee, J. S., Lee, S. W., Jo, K., Song, J. W., & Lee, J. C. (n.d.). Clinical Characteristics of and Risk Factors for Fever after Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration : A Retrospective Study Involving 6336 Patients. 5–7.Murthi, M., Donna, E., Arias, S., Villamizar, N. R., Nguyen, D. M., & Biomedical, A. F. (2020). Diagnostic Accuracy of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration ( EBUS-TBNA ) in Real Life. 7(April). https://doi.org/10.3389/fmed.2020.00118Shafiek, H., Fiorentino, F., David, A., Serra, E., Esteban, B., Martinez, R., Angels, M., Moyano, P., Sala, E., Sauleda, J., & Cosío, B. G. (2014). 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