Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético

ilustraciones, diagramas, tablas

Autores:
Escobar Soto, Steffanny
Tipo de recurso:
Fecha de publicación:
2024
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/86488
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/86488
https://repositorio.unal.edu.co/
Palabra clave:
610 - Medicina y salud::612 - Fisiología humana
610 - Medicina y salud::615 - Farmacología y terapéutica
610 - Medicina y salud::616 - Enfermedades
ENFERMOS CRONICOS
ENFERMEDADES CARDIOVASCULARES
EJERCICIO
EJERCICIOS TERAPEUTICOS
Chronically ill
Cardiovascular system - Diseases
Exercise
Exercise therapy
Obstrucción parcial del flujo sanguíneo
Entrenamiento Kaatsu
Fisioterapia
Ensayos clínicos aleatorizados
Kaatsu training
Blood flow restriction
Physiotherapy
Randomized clinical trials
Rights
openAccess
License
Atribución-NoComercial-SinDerivadas 4.0 Internacional
id UNACIONAL2_91c610ccecb8d11facc496aa128e9662
oai_identifier_str oai:repositorio.unal.edu.co:unal/86488
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético
dc.title.translated.eng.fl_str_mv Effectiveness of training with partial blood flow restriction in adults with pathologies of cardiovascular and musculoskeletal origin
title Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético
spellingShingle Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético
610 - Medicina y salud::612 - Fisiología humana
610 - Medicina y salud::615 - Farmacología y terapéutica
610 - Medicina y salud::616 - Enfermedades
ENFERMOS CRONICOS
ENFERMEDADES CARDIOVASCULARES
EJERCICIO
EJERCICIOS TERAPEUTICOS
Chronically ill
Cardiovascular system - Diseases
Exercise
Exercise therapy
Obstrucción parcial del flujo sanguíneo
Entrenamiento Kaatsu
Fisioterapia
Ensayos clínicos aleatorizados
Kaatsu training
Blood flow restriction
Physiotherapy
Randomized clinical trials
title_short Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético
title_full Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético
title_fullStr Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético
title_full_unstemmed Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético
title_sort Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético
dc.creator.fl_str_mv Escobar Soto, Steffanny
dc.contributor.advisor.none.fl_str_mv Mancera Soto, Erica Mabel
Villamil Parra, Wilder Andrés
dc.contributor.author.none.fl_str_mv Escobar Soto, Steffanny
dc.subject.ddc.spa.fl_str_mv 610 - Medicina y salud::612 - Fisiología humana
610 - Medicina y salud::615 - Farmacología y terapéutica
610 - Medicina y salud::616 - Enfermedades
topic 610 - Medicina y salud::612 - Fisiología humana
610 - Medicina y salud::615 - Farmacología y terapéutica
610 - Medicina y salud::616 - Enfermedades
ENFERMOS CRONICOS
ENFERMEDADES CARDIOVASCULARES
EJERCICIO
EJERCICIOS TERAPEUTICOS
Chronically ill
Cardiovascular system - Diseases
Exercise
Exercise therapy
Obstrucción parcial del flujo sanguíneo
Entrenamiento Kaatsu
Fisioterapia
Ensayos clínicos aleatorizados
Kaatsu training
Blood flow restriction
Physiotherapy
Randomized clinical trials
dc.subject.lemb.spa.fl_str_mv ENFERMOS CRONICOS
ENFERMEDADES CARDIOVASCULARES
EJERCICIO
EJERCICIOS TERAPEUTICOS
dc.subject.lemb.eng.fl_str_mv Chronically ill
Cardiovascular system - Diseases
Exercise
Exercise therapy
dc.subject.proposal.spa.fl_str_mv Obstrucción parcial del flujo sanguíneo
Entrenamiento Kaatsu
Fisioterapia
Ensayos clínicos aleatorizados
dc.subject.proposal.eng.fl_str_mv Kaatsu training
Blood flow restriction
Physiotherapy
Randomized clinical trials
description ilustraciones, diagramas, tablas
publishDate 2024
dc.date.accessioned.none.fl_str_mv 2024-07-16T20:52:59Z
dc.date.available.none.fl_str_mv 2024-07-16T20:52:59Z
dc.date.issued.none.fl_str_mv 2024
dc.type.spa.fl_str_mv Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/TM
status_str acceptedVersion
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/86488
dc.identifier.instname.spa.fl_str_mv Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv https://repositorio.unal.edu.co/
url https://repositorio.unal.edu.co/handle/unal/86488
https://repositorio.unal.edu.co/
identifier_str_mv Universidad Nacional de Colombia
Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.references.spa.fl_str_mv Asociación Médica Mundial (AMM). (2014). Declaración de HELSINKI de la AMM: Principios éticos para las investigaciones médicas en seres humanos. chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://minciencias.gov.co/sites/default/files/ckeditor_files/6.pdf
Barbalho, M., Rocha, A. C., Seus, T. L., Raiol, R., Del Vecchio, F. B., & Coswig, V. S. (2019). Addition of blood flow restriction to passive mobilization reduces the rate of muscle wasting in elderly patients in the intensive care unit: A within-patient randomized trial. Clinical Rehabilitation, 33(2), 233-240. https://doi.org/10.1177/0269215518801440
Barili, A., Corralo, V. da S., Cardoso, A. M., Mânica, A., Bonadiman, B. da S. R., Bagatini, M. D., Da Silva-Grigoletto, M. E., de Oliveira, G. G., & De Sá, C. A. (2018). Acute responses of hemodynamic and oxidative stress parameters to aerobic exercise with blood flow restriction in hypertensive elderly women. Molecular Biology Reports, 45(5), 1099-1109. https://doi.org/10.1007/s11033-018-4261-1
Cancio, J. M., Sgromolo, N. M., & Rhee, P. C. (2019). Blood Flow Restriction Therapy after Closed Treatment of Distal Radius Fractures. Journal of Wrist Surgery, 08(04), 288-294. https://doi.org/10.1055/s-0039-1685455
Cardoso, R. K., Araujo, A. M., Del Vechio, F. B., Bohlke, M., Barcellos, F. C., Oses, J. P., de Freitas, M. P., & Rombaldi, A. J. (2020). Intradialytic exercise with blood flow restriction is more effective than conventional exercise in improving walking endurance in hemodialysis patients: A randomized controlled trial. Clinical Rehabilitation, 34(1), 91-98. Medline. https://doi.org/10.1177/0269215519880235
Centner, C., Wiegel, P., Gollhofer, A., & König, D. (2019). Effects of Blood Flow Restriction Training on Muscular Strength and Hypertrophy in Older Individuals: A Systematic Review and Meta-Analysis. Sports Medicine (Auckland, N.Z.), 49(1), 95-108. Medline. https://doi.org/10.1007/s40279-018-0994-1
Clarkson, M. J., Conway, L., & Warmington, S. A. (2017). Blood flow restriction walking and physical function in older adults: A randomized control trial. Journal of Science and Medicine in Sport, 20(12), 1041-1046. https://doi.org/10.1016/j.jsams.2017.04.012
Clínica Universidad de Navarra. (2023). Sistema músculo-esquéletico. https://www.cun.es/diccionario-medico/terminos/sistema-musculo-esqueletico
Constantinou, A., Mamais, I., Papathanasiou, G., Lamnisos, D., & Stasinopoulos, D. (2022). Comparing hip and knee focused exercises versus hip and knee focused exercises with the use of blood flow restriction training in adults with patellofemoral pain. European Journal of Physical and Rehabilitation Medicine, 58(2), 225-235. Medline. https://doi.org/10.23736/S1973-9087.22.06691-6
Cook, S. B., & Cleary, C. J. (2019). Progression of blood flow restricted resistance training in older adults at risk of mobility limitations. Frontiers in Physiology, 10(JUN). Embase. https://doi.org/10.3389/fphys.2019.00738
Cook, S. B., LaRoche, D. P., Villa, M. R., Barile, H., & Manini, T. M. (2017). Blood flow restricted resistance training in older adults at risk of mobility limitations. Experimental Gerontology, 99, 138-145. https://doi.org/10.1016/j.exger.2017.10.004
Corrêa, H. L., Neves, R. V. P., Deus, L. A., Maia, B. C. H., Maya, A. T., Tzanno-Martins, C., Souza, M. K., Silva, J. A. B., Haro, A. S., Costa, F., Moraes, M. R., Simões, H. G., Prestes, J., Stone, W., & Rosa, T. S. (2021). Low-load resistance training with blood flow restriction prevent renal function decline: The role of the redox balance, angiotensin 1–7 and vasopressin✰,✰✰. Physiology & Behavior, 230, 113295. https://doi.org/10.1016/j.physbeh.2020.113295
Curran, M. T., Bedi, A., Mendias, C. L., Wojtys, E. M., Kujawa, M. V., & Palmieri-Smith, R. M. (2020). Blood Flow Restriction Training Applied With High-Intensity Exercise Does Not Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial. The American Journal of Sports Medicine, 48(4), 825-837. https://doi.org/10.1177/0363546520904008
Dogra, S., Dunstan, D. W., Sugiyama, T., Stathi, A., Gardiner, P. A., & Owen, N. (2022). Active Aging and Public Health: Evidence, Implications, and Opportunities. Annual Review of Public Health, 43(1), 439-459. https://doi.org/10.1146/annurev-publhealth-052620-091107
Eikens, F., Lay, D., Behringer, M., & Predel, H. G. (2018). Influence of blood flow restriction training on post exercise hypotension in hypertensive subjects -a randomized controlled trial. Nieren- Und Hochdruckkrankheiten, 47(11), 558. Embase. https://doi.org/10.5414/NHX02005
Erickson, L. N., Lucas, K. C. H., Davis, K. A., Jacobs, C. A., Thompson, K. L., Hardy, P. A., Andersen, A. H., Fry, C. S., & Noehren, B. W. (2019). Effect of Blood Flow Restriction Training on Quadriceps Muscle Strength, Morphology, Physiology, and Knee Biomechanics Before and After Anterior Cruciate Ligament Reconstruction: Protocol for a Randomized Clinical Trial. Physical Therapy, 99(8), 1010-1019. https://doi.org/10.1093/ptj/pzz062
Ferraz, R. B., Gualano, B., Rodrigues, R., Kurimori, C. O., Fuller, R., Lima, F. R., DE Sá-Pinto, A. L., & Roschel, H. (2018). Benefits of Resistance Training with Blood Flow Restriction in Knee Osteoarthritis. Medicine and Science in Sports and Exercise, 50(5), 897-905. https://doi.org/10.1249/MSS.0000000000001530
Franz, A., Ji, S., Bittersohl, B., Zilkens, C., & Behringer, M. (2022). Impact of a Six-Week Prehabilitation With Blood-Flow Restriction Training on Pre- and Postoperative Skeletal Muscle Mass and Strength in Patients Receiving Primary Total Knee Arthroplasty. Frontiers in Physiology, 13((Franz A., alexander.franz@ukbonn.de) Department of Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany). Embase. https://doi.org/10.3389/fphys.2022.881484
Giles, L., Webster, K. E., McClelland, J., & Cook, J. L. (2017). Quadriceps strengthening with and without blood flow restriction in the treatment of patellofemoral pain: A double-blind randomised trial. British Journal of Sports Medicine, 51(23), 1688-1694. https://doi.org/10.1136/bjsports-2016-096329
Harper, S. A., Roberts, L. M., Layne, A. S., Jaeger, B. C., Gardner, A. K., Sibille, K. T., Wu, S. S., Vincent, K. R., Fillingim, R. B., Manini, T. M., & Buford, T. W. (2019). Blood-flow restriction resistance exercise for older adults with knee osteoarthritis: A pilot randomized clinical trial. Journal of Clinical Medicine, 8(2). Embase. https://doi.org/10.3390/jcm8020265
Higgins, J., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M., & Welch, V. (2023). Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane, 2023. www.training.cochrane.org/handbook.
Hughes, L., Paton, B., Haddad, F., Rosenblatt, B., Gissane, C., & Patterson, S. D. (2018). Comparison of the acute perceptual and blood pressure response to heavy load and light load blood flow restriction resistance exercise in anterior cruciate ligament reconstruction patients and non-injured populations. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 33, 54-61. https://doi.org/10.1016/j.ptsp.2018.07.002
Hughes, L., Paton, B., Rosenblatt, B., Gissane, C., & Patterson, S. D. (2017). Blood flow restriction training in clinical musculoskeletal rehabilitation: A systematic review and meta-analysis. British Journal of Sports Medicine, 51(13), 1003-1011. Medline. https://doi.org/10.1136/bjsports-2016-097071
Hughes, L., Patterson, S. D., Haddad, F., Rosenblatt, B., Gissane, C., McCarthy, D., Clarke, T., Ferris, G., Dawes, J., & Paton, B. (2019). Examination of the comfort and pain experienced with blood flow restriction training during post-surgery rehabilitation of anterior cruciate ligament reconstruction patients: A UK National Health Service trial. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 39, 90-98. https://doi.org/10.1016/j.ptsp.2019.06.014
Hughes, L., Rosenblatt, B., Haddad, F., Gissane, C., McCarthy, D., Clarke, T., Ferris, G., Dawes, J., Paton, B., & Patterson, S. D. (2019). Comparing the Effectiveness of Blood Flow Restriction and Traditional Heavy Load Resistance Training in the Post-Surgery Rehabilitation of Anterior Cruciate Ligament Reconstruction Patients: A UK National Health Service Randomised Controlled Trial. Sports Medicine (Auckland, N.Z.), 49(11), 1787-1805. https://doi.org/10.1007/s40279-019-01137-2
Instituto Nacional de Salud. (2013). Boletín N°1 ONS (Observatorio Nacional de Salud): Enfermedad cardiovascular principal causa de muerte en Colombia (https://www.ins.gov.co/Direcciones/ONS/Boletines/boletin_web_ONS/referencias.html). Ministerio de Salud y Protección Social.
Iversen, E., Røstad, V., & Larmo, A. (2016). Intermittent blood flow restriction does not reduce atrophy following anterior cruciate ligament reconstruction. Journal of Sport and Health Science, 5(1), 115-118. https://doi.org/10.1016/j.jshs.2014.12.005
Jack, R. A., Lambert, B. S., Hedt, C. A., Delgado, D., Goble, H., & McCulloch, P. C. (2022). Blood Flow Restriction Therapy Preserves Lower Extremity Bone and Muscle Mass After ACL Reconstruction. Sports Health, (Jack R.A.; Lambert B.S.; Hedt C.A.; Delgado D.; Goble H.; McCulloch P.C.) Orthopedic Biomechanics Research Laboratory, Department of Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, TX, 19417381221101006. Medline. https://doi.org/10.1177/19417381221101006
Jensen, K. Y., Jacobsen, M., Schrøder, H. D., Aagaard, P., Nielsen, J. L., Jørgensen, A. N., Boyle, E., Bech, R. D., Rosmark, S., Diederichsen, L. P., & Frandsen, U. (2019). The immune system in sporadic inclusion body myositis patients is not compromised by blood-flow restricted exercise training. Arthritis Research & Therapy, 21(1), 293. https://doi.org/10.1186/s13075-019-2036-2
Jønsson, A., Johansen, C., Rolving, N., & Pfeiffer-Jensen, M. (2021). Feasibility and estimated efficacy of blood flow restricted training in female patients with rheumatoid arthritis: A randomized controlled pilot study. Scandinavian Journal of Rheumatology, 50(3), 169-177. https://doi.org/10.1080/03009742.2020.1829701
Kambič, T., Novaković, M., Tomažin, K., Strojnik, V., Božič-Mijovski, M., & Jug, B. (2021). Hemodynamic and Hemostatic Response to Blood Flow Restriction Resistance Exercise in Coronary Artery Disease: A Pilot Randomized Controlled Trial. The Journal of Cardiovascular Nursing, 36(5), 507-516. Medline. https://doi.org/10.1097/JCN.0000000000000699
Kambic, T., Novakovic, M., Tomazin, K., Strojnik, V., & Jug, B. (2019). Blood flow restriction resistance exercise improves muscle strength and hemodynamics, but not vascular function in coronary artery disease patients: A pilot randomized controlled trial. Frontiers in Physiology, 10(JUN). Embase. https://doi.org/10.3389/fphys.2019.00656
Karanasios, S., Korakakis, V., Moutzouri, M., Xergia, S. Α., Tsepis, Ε., & Gioftsos, G. (2022). Low-load resistance training with blood flow restriction is effective for managing lateral elbow tendinopathy: A randomized, sham-controlled trial. The Journal of Orthopaedic and Sports Physical Therapy, (Karanasios S.; Moutzouri M.; Gioftsos G.) Laboratory of Advanced Physiotherapy (LAdPhys), Physiotherapy Department, School of Health and Care Sciences, University of West Attica, Greece, 1-30. Medline. https://doi.org/10.2519/jospt.2022.11211
Korakakis, V., Whiteley, R., & Giakas, G. (2018). Low load resistance training with blood flow restriction decreases anterior knee pain more than resistance training alone. A pilot randomised controlled trial. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 34, 121-128. https://doi.org/10.1016/j.ptsp.2018.09.007
Ladlow, P., Coppack, R. J., Dharm-Datta, S., Conway, D., Sellon, E., Patterson, S. D., & Bennett, A. N. (2018). Low-load resistance training with blood flow restriction improves clinical outcomes in musculoskeletal rehabilitation: A single-blind randomized controlled trial. Frontiers in Physiology, 9(SEP). Embase. https://doi.org/10.3389/fphys.2018.01269
Letieri, R. V., Furtado, G. E., Barros, P. M. N., Farias, M. J. A. D., Antunez, B. F., Gomes, B. B., & Teixeira, A. M. M. B. (2019). Effect of 16-Week Blood Flow Restriction Exercise on Functional Fitness in Sarcopenic Women: A Randomized Controlled Trial. International Journal of Morphology, 37(1), 59-64. https://doi.org/10.4067/S0717-95022019000100059
Li, N., Yang, J., & Liao, Y. (2023). The effect of blood flow restriction training combined with electrical muscle stimulation on neuromuscular adaptation: A randomized controlled trial. Frontiers in Physiology, 14, 1182249. https://doi.org/10.3389/fphys.2023.1182249
Lixandrão, M. E., Roschel, H., Ugrinowitsch, C., Miquelini, M., Alvarez, I. F., & Libardi, C. A. (2019). Blood-Flow Restriction Resistance Exercise Promotes Lower Pain and Ratings of Perceived Exertion Compared With Either High- or Low-Intensity Resistance Exercise Performed to Muscular Failure. Journal of Sport Rehabilitation, 28(7), 706-710. https://doi.org/10.1123/jsr.2018-0030
Londoño, J., Peláez Ballestas, I., Cuervo, F., Angarita, I., Giraldo, R., Rueda, J. C., Ballesteros, J. G., Baquero, R., Forero, E., Cardiel, M., Saldarriaga, E., Vásquez, A., Arias, S., Valero, L., González, C., Ramírez, J., Toro, C., & Santos, A. M. (2018). Prevalencia de la enfermedad reumática en Colombia, según estrategia COPCORD-Asociación Colombiana de Reumatología. Estudio de prevalencia de enfermedad reumática en población colombiana mayor de 18 años. Revista Colombiana de Reumatología, 25(4), 245-256. https://doi.org/10.1016/j.rcreu.2018.08.003
Loprinzi, P. D. (2016). Multimorbidity, cognitive function, and physical activity. AGE, 38(1), 8. https://doi.org/10.1007/s11357-016-9874-5
Madarame, H., Kurano, M., Fukumura, K., Fukuda, T., & Nakajima, T. (2013). Haemostatic and inflammatory responses to blood flow-restricted exercise in patients with ischaemic heart disease: A pilot study. Clinical Physiology and Functional Imaging, 33(1), 11-17. https://doi.org/10.1111/j.1475-097X.2012.01158.x
Mahmoud, W. S., Osailan, A., Ahmed, A. S., Elnaggar, R. K., & Radwan, N. L. (2021). Optimal parameters of blood flow restriction and resistance training on quadriceps strength and cross-sectional area and pain in knee osteoarthritis. Isokinetics and Exercise Science, 29(4), 393-402. Embase. https://doi.org/10.3233/IES-200235
Majors, I. B., Mears, S. C., Oholendt, C. K., Hargett, N. A., Barnes, C. L., & Stambough, J. B. (2022). Does Blood Flow Restriction Therapy Improve Leg Strength in Patients With a Painful Total Knee Arthroplasty? The Journal of Arthroplasty, 37(6), 1064-1068. https://doi.org/10.1016/j.arth.2022.02.021
Mason, J. S., Crowell, M. S., Brindle, R. A., Dolbeer, J. A., Miller, E. M., Telemeco, T. A., & Goss, D. L. (2022). The Effect of Blood Flow Restriction Training on Muscle Atrophy Following Meniscal Repair or Chondral Restoration Surgery in Active Duty Military: A Randomized Controlled Trial. Journal of Sport Rehabilitation, 31(1), 77-84. Medline. https://doi.org/10.1123/jsr.2020-0518
Mason, M. J. S., Owens, J. G., & Brown, L. W. J. (2018). Blood Flow Restriction Training: Current and Future Applications for the Rehabilitation of Musculoskeletal Injuries. Techniques in Orthopaedics, 33(2), 71-71. https://doi.org/10.1097/BTO.0000000000000301
May, A. K., Brandner, C. R., & Warmington, S. A. (2017). Hemodynamic responses are reduced with aerobic compared with resistance blood flow restriction exercise. Physiological Reports, 5(3). https://doi.org/10.14814/phy2.13142
McGuinness, L. A., & Higgins, J. P. T. (2020). Risk-of-bias VISualization (robvis): An R package and Shinyweb app for visualizing risk-of-bias assessments. Research Synthesis Methods. 10.1002/jrsm.1411
Miller, B. C., Tirko, A. W., Shipe, J. M., Sumeriski, O. R., & Moran, K. (2021). The Systemic Effects of Blood Flow Restriction Training: A Systematic Review. International Journal of Sports Physical Therapy, 16(4). https://doi.org/10.26603/001c.25791
Nagy-Pénzes, G., Vincze, F., & Bíró, É. (2022). A School Intervention’s Impact on Adolescents’ Health-Related Knowledge and Behavior. Frontiers in Public Health, 10, 822155. https://doi.org/10.3389/fpubh.2022.822155
National Cancer Institute. (2023). Cardiovascular Disease Definition. https://www.cancer.gov/espanol/publicaciones/diccionarios/diccionario-cancer/def/enfermedad-cardiovascular
Natsume, T., Ozaki, H., Saito, A. I., Abe, T., & Naito, H. (2015). Effects of Electrostimulation with Blood Flow Restriction on Muscle Size and Strength. Medicine & Science in Sports & Exercise, 47(12), 2621-2627. https://doi.org/10.1249/MSS.0000000000000722
Nielsen, J. L., Frandsen, U., Prokhorova, T., Bech, R. D., Nygaard, T., Suetta, C., & Aagaard, P. (2017). Delayed Effect of Blood Flow–restricted Resistance Training on Rapid Force Capacity. Medicine & Science in Sports & Exercise, 49(6), 1157-1167. https://doi.org/10.1249/MSS.0000000000001208
Ogawa, H., Nakajima, T., Shibasaki, I., Nasuno, T., Kaneda, H., Katayanagi, S., Ishizaka, H., Mizushima, Y., Uematsu, A., Yasuda, T., Yagi, H., Toyoda, S., Hortobágyi, T., Mizushima, T., Inoue, T., & Fukuda, H. (2021). Low-intensity resistance training with moderate blood flow restriction appears safe and increases skeletal muscle strength and size in cardiovascular surgery patients: A pilot study. Journal of Clinical Medicine, 10(3), 1-13. Embase. https://doi.org/10.3390/jcm10030547
Omer, K., Nermin, G., Ali, A., Mehmet, A., Unal, D., Sezen, K. S., & Hakan, K. (2017). Lesão de isquemia‐reperfusão induzida por torniquete: Comparação dos efeitos antioxidantes de propofol e cetamina em doses baixas. Brazilian Journal of Anesthesiology, 67(3), 246-250. https://doi.org/10.1016/j.bjan.2016.10.007
Owen, N., Healy, G. N., Dempsey, P. C., Salmon, J., Timperio, A., Clark, B. K., Goode, A. D., Koorts, H., Ridgers, N. D., Hadgraft, N. T., Lambert, G., Eakin, E. G., Kingwell, B. A., & Dunstan, D. W. (2020). Sedentary Behavior and Public Health: Integrating the Evidence and Identifying Potential Solutions. Annual Review of Public Health, 41(1), 265-287. https://doi.org/10.1146/annurev-publhealth-040119-094201
Patterson, S. D., Hughes, L., Head, P., Warmington, S., & Brandner, C. (2017). Blood flow restriction training: A novel approach to augment clinical rehabilitation: how to do it. British Journal of Sports Medicine, 51(23), 1648-1649. https://doi.org/10.1136/bjsports-2017-097738
Patterson, S. D., Hughes, L., Warmington, S., Burr, J., Scott, B. R., Owens, J., Abe, T., Nielsen, J. L., Libardi, C. A., Laurentino, G., Neto, G. R., Brandner, C., Martin-Hernandez, J., & Loenneke, J. (2019). Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety. Frontiers in Physiology, 10, 533. https://doi.org/10.3389/fphys.2019.00533
Prince, S. A., Gresty, K. M., Reed, J. L., Wright, E., Tremblay, M. S., & Reid, R. D. (2014). Individual, social and physical environmental correlates of sedentary behaviours in adults: A systematic review protocol.
Przkora, R., Sibille, K., Victor, S., Meroney, M., Leeuwenburgh, C., Gardner, A., Vasilopoulos, T., & Parvataneni, H. K. (2021). Blood flow restriction exercise to attenuate postoperative loss of function after total knee replacement: A randomized pilot study. European Journal of Translational Myology, 31(3). Embase. https://doi.org/10.4081/ejtm.2021.9932
Resolución No 8430 de Octubre 4 de 1993, Pub. L. No. Resolución 8430 de 1993. chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/DE/DIJ/RESOLUCION-8430-DE-1993.PDF
Rodrigues R; Ferraz RB; Kurimori CO; Guedes LK; Lima FR; de Sa-Pinto AL; Gualano B; Roschel H. (2020). Low-load resistance training with blood flow restriction increases muscle function, mass and functionality in women with rheumatoid arthritis [with consumer summary]. Arthritis Care & Research 2020 Jun;72(6):787-797. Downloaded from PEDro http://www.pedro.org.au.
Saraf, A., Goyal, M., & Goyal, K. (2022). Blood Flow Restriction Training-An Overview and Implication in New Generation Physical Therapy: A Narrative Review. Journal of Lifestyle Medicine, 12(2), 63-68. https://doi.org/10.15280/jlm.2022.12.2.63
Sato, Y. (2005). The history and future of KAATSU Training. International Journal of KAATSU Training Research, 1(1), 1-5. https://doi.org/10.3806/ijktr.1.1
Segal, N. A., Williams, G. N., Davis, M. C., Wallace, R. B., & Mikesky, A. E. (2015). Efficacy of Blood Flow–Restricted, Low-Load Resistance Training in Women with Risk Factors for Symptomatic Knee Osteoarthritis. PM&R, 7(4), 376-384. https://doi.org/10.1016/j.pmrj.2014.09.014
Sgromolo, N. M., Cancio, J. M., & Rhee, P. C. (2020). Safety and Efficacy of Blood Flow Restriction Therapy after Operative Management of Distal Radius Fractures: A Randomized Controlled Study. Journal of Wrist Surgery, 09(04), 345-352. https://doi.org/10.1055/s-0040-1712504
Silva, I. B., Barbosa, J. B. N., Araújo, A. X. P., & Marinho, P. E. M. (2021). Effect of an exercise program with blood flow restriction on the muscular strength of patients with chronic kidney disease: A randomized clinical trial. Journal of Bodywork and Movement Therapies, 28, 187-192. https://doi.org/10.1016/j.jbmt.2021.06.022
Sugawara, J., Tomoto, T., & Tanaka, H. (2015). Impact of leg blood flow restriction during walking on central arterial hemodynamics. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 309(7), R732-R739. https://doi.org/10.1152/ajpregu.00095.2015
Tramer, J. S., Khalil, L. S., Jildeh, T. R., Abbas, M. J., McGee, A., Lau, M. J., Moutzouros, V., & Okoroha, K. R. (2022). Blood Flow Restriction Therapy for Two Weeks Prior to Anterior Cruciate Ligament Reconstruction Did not Impact Quadriceps Strength Compared to Standard Therapy. Arthroscopy: The Journal of Arthroscopic & Related Surgery. https://doi.org/10.1016/j.arthro.2022.06.027
Vanwye, W. R., & Weatherholt, A. M. (2017). Blood Flow Restriction Training: Implementation into Clinical Practice.
Villamil Parra, W. A. V. (2016). REVISIÓN SISTEMÁTICA DE LA EFICACIA DEL EJERCICIO FÍSICO EN PACIENTES ADULTOS HOSPITALIZADOS EN UCI. Universidad Nacional de Colombia - Sede Bogotá.
Wernbom, M., Schoenfeld, B. J., Paulsen, G., Bjørnsen, T., Cumming, K. T., Aagaard, P., Clark, B. C., & Raastad, T. (2020). Commentary: Can Blood Flow Restricted Exercise Cause Muscle Damage? Commentary on Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety. Frontiers in Physiology, 11, 243. https://doi.org/10.3389/fphys.2020.00243
Zhang, X., Xie, W., Chen, L., Xu, G., Wu, L., Li, Y., & Wu, Y. (2022). Blood Flow Restriction Training for the Intervention of Sarcopenia: Current Stage and Future Perspective. Frontiers in Medicine, 9, 894996. https://doi.org/10.3389/fmed.2022.894996
Zhao Y; Zheng Y; Ma X; Qiang L; Lin A; Zhou M. (2022). Low-intensity resistance exercise combined with blood flow restriction is more conducive to regulate blood pressure and autonomic nervous system in hypertension patients-compared with high-intensity and low-intensity resistance exercise. Frontiers in Physiology 2022 Apr20;13(833809):Epub. Downloaded from PEDro http://www.pedro.org.au.
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dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia
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dc.publisher.faculty.spa.fl_str_mv Facultad de Medicina
dc.publisher.place.spa.fl_str_mv Bogotá, Colombia
dc.publisher.branch.spa.fl_str_mv Universidad Nacional de Colombia - Sede Bogotá
institution Universidad Nacional de Colombia
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spelling Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Mancera Soto, Erica Mabel78c6f6706f764e0fdc069d4c5643e56eVillamil Parra, Wilder Andrésebdaa333150d409c0412070d1a6066c9Escobar Soto, Steffanny4f11121f042b0202e24025e8c25ba8e92024-07-16T20:52:59Z2024-07-16T20:52:59Z2024https://repositorio.unal.edu.co/handle/unal/86488Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramas, tablasIntroducción: A través de los años se ha presentado un auge en la implementación del entrenamiento con obstrucción parcial del flujo sanguíneo (BFR) en personas potencialmente sanas, sin embargo, hay poca claridad frente a qué tan efectivo es este método en personas con carga de morbilidad asociada a la enfermedad en comparación a los procesos de fisioterapia convencional. Objetivo: Determinar la efectividad del entrenamiento con obstrucción parcial del BFR en adultos con patologías de origen cardiovascular y musculoesquelético. Método: Se realizó una búsqueda sistemática en las bases de datos Science direct, Pubmed, Embase y Pedro. Fueron seleccionados ensayos clínicos aleatorizados que relacionaran el entrenamiento BFR y su aplicación en personas con patologías cardiovascular (CV) o musculoesquelética (MSK). Se realizó una matriz de análisis final cuyo contenido fue evaluado por pares y posteriormente a través del software RevMan de Cochrane se obtuvo la significancia y heterogeneidad de los resultados, igualmente se evaluó la calidad y el riesgo de sesgo de los estudios. Resultados: Se identificaron 39 estudios en la matriz de análisis de los cuales 20 fueron seleccionados para el análisis cuantitativo relacionando 43 variables MSK y 4 variables CV. Posterior a la sistematización de las variables se agruparon los resultados en las categorías: 1) Desempeño muscular, 2) Características antropométricas, 3) Funcionalidad y calidad de vida y 4) respuesta fisiológica al ejercicio, y estas a su vez fueron diferenciadas en dos grupos de análisis: Artículos de baja y de alta heterogeneidad. No hubo efecto a favor del entrenamiento BFR en la CSA del cuádriceps con una heterogeneidad baja I2=0% y Chi2 = 0,20, tampoco lo hubo para la fuerza isocinética del cuádriceps, sin embargo este último con I2=34% y Chi2 = 4,53 con alta heterogeneidad; para la circunferencia femoral no hubo resultados significativos p = 0,70. Para las características VIII Efectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesquelético como la masa muscular total y el IMC aumentaron en pacientes sarcopénicas (p =0,01), el dolor fue una de las medidas de funcionalidad que registró mayor efecto a favor del BFR, así como las pruebas funcionales y cuestionarios auto reportados, y frente a la respuesta fisiológica se muestras efectos de adaptación crónicas a favor del BFR similares a los registrados en la práctica de ejercicio de alta intensidad. Conclusiones: La combinación de entrenamiento convencional con BFR muestra una significancia clínica en personas con alguna patología asociada en variables como el dolor, funcionalidad y calidad de vida, así como en la disminución de la atrofia post quirúrgica a pesar de no demostrar una diferencia estadística significativa en esta revisión sistemática, por lo cual el BFR puede tener mayor eficacia en comparación a la fisioterapia convencional; se requiere poder determinar parámetros de prescripción específicos en cuanto a recomendaciones de AOP (presión de oclusión arterial) y el porcentaje de intensidad generalmente dada en RM para generar las modificaciones anatómicas y fisiológicas esperadas y la replicabilidad necesaria para intervención e investigación en el área (texto tomado de la fuente).Introduction: Over the years there has been a boom in the implementation of training with partial blood flow obstruction (BFR) in potentially healthy people, however, there is little clarity regarding how effective this method is in people with burden of blood flow. morbidity associated with the disease compared to conventional physiotherapy processes. Objective: Determine the effectiveness of training with partial obstruction of the BFR in adults with pathologies of cardiovascular and musculoskeletal origin. Method: A systematic search was carried out in the Science direct, Pubmed, Embase and Pedro databases. Randomized clinical trials were selected that related BFR and its application in people with cardiovascular (CV) or musculoskeletal (MSK) pathologies. A final analysis matrix was carried out, the content of which was evaluated by peers and subsequently, through Cochrane's RevMan software, the significance and heterogeneity of the results was obtained, and the quality and risk of bias of the studies were also evaluated. Results: 39 studies were identified in the analysis matrix, of which 20 were selected for quantitative analysis relating 43 MSK variables and 4 CV variables. After the systematization of the variables, the results were grouped into the categories: 1) Muscular performance, 2) Anthropometric characteristics, 3) Functionality and quality of life and 4) physiological response to exercise, and these in turn were differentiated into two groups. analysis: Articles of low and high heterogeneity. There was no effect in favor of BFR training on quadriceps CSA with low heterogeneity I2=0% and Chi2 = 0.20, nor was there any effect for quadriceps isokinetic strength, however the latter with I2=34% and Chi2 = 4.53 with high heterogeneity; for femoral circumference there were no significant results p = 0.70. For characteristics VIII Effectiveness of training with partial obstruction of blood flow in adults with pathologies of cardiovascular and musculoskeletal origin, such as total muscle mass and BMI increased in sarcopenic patients (p =0.01), pain was one of the measures of functionality that registered a greater effect in favor of the BFR, as well as the functional tests and self-reported questionnaires, and compared to the physiological response, chronic adaptation effects were shown in favor of the BFR similar to those recorded in the practice of high intensity exercise. Conclusions: The combination of conventional training with BFR shows clinical significance in people with some associated pathology in variables such as pain, functionality and quality of life, as well as in the reduction of post-surgical atrophy despite not demonstrating a significant statistical difference. . in this systematic review, which is why BFR may be more effective compared to conventional physiotherapy; It is necessary to be able to determine specific prescription parameters in terms of AOP (arterial occlusion pressure) recommendations and the percentage of intensity generally given in MRI to generate the expected anatomical and physiological modifications and the necessary replicability for intervention and research in the area.MaestríaMagister en Fisioterapia del Deporte y la Actividad físicaMétodo descrito por Cochrane para revisiones sistemáticas. Se realizó una búsqueda sistemática en las bases de datos Science direct, Pubmed, Embase y Pedro. Fueron seleccionados ensayos clínicos aleatorizados que relacionaran el entrenamiento BFR y su aplicación en personas con patologías de origen cardiovascular (CV) o musculoesquelética (MSK). Se realizó una matriz de análisis final cuyo contenido fue evaluado por pares y posteriormente a través del software RevMan de Cochrane se obtuvo la significancia y heterogeneidad de los resultados, igualmente se evaluó la calidad y el riesgo de sesgo de los estudios.xvii, 135 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Maestría en Fisioterapia del Deporte y la Actividad FísicaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::612 - Fisiología humana610 - Medicina y salud::615 - Farmacología y terapéutica610 - Medicina y salud::616 - EnfermedadesENFERMOS CRONICOSENFERMEDADES CARDIOVASCULARESEJERCICIOEJERCICIOS TERAPEUTICOSChronically illCardiovascular system - DiseasesExerciseExercise therapyObstrucción parcial del flujo sanguíneoEntrenamiento KaatsuFisioterapiaEnsayos clínicos aleatorizadosKaatsu trainingBlood flow restrictionPhysiotherapyRandomized clinical trialsEfectividad del entrenamiento con obstrucción parcial del flujo sanguíneo en personas adultas con patologías de origen cardiovascular y musculoesqueléticoEffectiveness of training with partial blood flow restriction in adults with pathologies of cardiovascular and musculoskeletal originTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMAsociación Médica Mundial (AMM). (2014). Declaración de HELSINKI de la AMM: Principios éticos para las investigaciones médicas en seres humanos. chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://minciencias.gov.co/sites/default/files/ckeditor_files/6.pdfBarbalho, M., Rocha, A. C., Seus, T. L., Raiol, R., Del Vecchio, F. B., & Coswig, V. S. (2019). Addition of blood flow restriction to passive mobilization reduces the rate of muscle wasting in elderly patients in the intensive care unit: A within-patient randomized trial. Clinical Rehabilitation, 33(2), 233-240. https://doi.org/10.1177/0269215518801440Barili, A., Corralo, V. da S., Cardoso, A. M., Mânica, A., Bonadiman, B. da S. R., Bagatini, M. D., Da Silva-Grigoletto, M. E., de Oliveira, G. G., & De Sá, C. A. (2018). Acute responses of hemodynamic and oxidative stress parameters to aerobic exercise with blood flow restriction in hypertensive elderly women. Molecular Biology Reports, 45(5), 1099-1109. https://doi.org/10.1007/s11033-018-4261-1Cancio, J. M., Sgromolo, N. M., & Rhee, P. C. (2019). Blood Flow Restriction Therapy after Closed Treatment of Distal Radius Fractures. Journal of Wrist Surgery, 08(04), 288-294. https://doi.org/10.1055/s-0039-1685455Cardoso, R. K., Araujo, A. M., Del Vechio, F. B., Bohlke, M., Barcellos, F. C., Oses, J. P., de Freitas, M. P., & Rombaldi, A. J. (2020). Intradialytic exercise with blood flow restriction is more effective than conventional exercise in improving walking endurance in hemodialysis patients: A randomized controlled trial. Clinical Rehabilitation, 34(1), 91-98. Medline. https://doi.org/10.1177/0269215519880235Centner, C., Wiegel, P., Gollhofer, A., & König, D. (2019). Effects of Blood Flow Restriction Training on Muscular Strength and Hypertrophy in Older Individuals: A Systematic Review and Meta-Analysis. Sports Medicine (Auckland, N.Z.), 49(1), 95-108. Medline. https://doi.org/10.1007/s40279-018-0994-1Clarkson, M. J., Conway, L., & Warmington, S. A. (2017). Blood flow restriction walking and physical function in older adults: A randomized control trial. Journal of Science and Medicine in Sport, 20(12), 1041-1046. https://doi.org/10.1016/j.jsams.2017.04.012Clínica Universidad de Navarra. (2023). Sistema músculo-esquéletico. https://www.cun.es/diccionario-medico/terminos/sistema-musculo-esqueleticoConstantinou, A., Mamais, I., Papathanasiou, G., Lamnisos, D., & Stasinopoulos, D. (2022). Comparing hip and knee focused exercises versus hip and knee focused exercises with the use of blood flow restriction training in adults with patellofemoral pain. European Journal of Physical and Rehabilitation Medicine, 58(2), 225-235. Medline. https://doi.org/10.23736/S1973-9087.22.06691-6Cook, S. B., & Cleary, C. J. (2019). Progression of blood flow restricted resistance training in older adults at risk of mobility limitations. Frontiers in Physiology, 10(JUN). Embase. https://doi.org/10.3389/fphys.2019.00738Cook, S. B., LaRoche, D. P., Villa, M. R., Barile, H., & Manini, T. M. (2017). Blood flow restricted resistance training in older adults at risk of mobility limitations. Experimental Gerontology, 99, 138-145. https://doi.org/10.1016/j.exger.2017.10.004Corrêa, H. L., Neves, R. V. P., Deus, L. A., Maia, B. C. H., Maya, A. T., Tzanno-Martins, C., Souza, M. K., Silva, J. A. B., Haro, A. S., Costa, F., Moraes, M. R., Simões, H. G., Prestes, J., Stone, W., & Rosa, T. S. (2021). Low-load resistance training with blood flow restriction prevent renal function decline: The role of the redox balance, angiotensin 1–7 and vasopressin✰,✰✰. Physiology & Behavior, 230, 113295. https://doi.org/10.1016/j.physbeh.2020.113295Curran, M. T., Bedi, A., Mendias, C. L., Wojtys, E. M., Kujawa, M. V., & Palmieri-Smith, R. M. (2020). Blood Flow Restriction Training Applied With High-Intensity Exercise Does Not Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial. The American Journal of Sports Medicine, 48(4), 825-837. https://doi.org/10.1177/0363546520904008Dogra, S., Dunstan, D. W., Sugiyama, T., Stathi, A., Gardiner, P. A., & Owen, N. (2022). Active Aging and Public Health: Evidence, Implications, and Opportunities. Annual Review of Public Health, 43(1), 439-459. https://doi.org/10.1146/annurev-publhealth-052620-091107Eikens, F., Lay, D., Behringer, M., & Predel, H. G. (2018). Influence of blood flow restriction training on post exercise hypotension in hypertensive subjects -a randomized controlled trial. Nieren- Und Hochdruckkrankheiten, 47(11), 558. Embase. https://doi.org/10.5414/NHX02005Erickson, L. N., Lucas, K. C. H., Davis, K. A., Jacobs, C. A., Thompson, K. L., Hardy, P. A., Andersen, A. H., Fry, C. S., & Noehren, B. W. (2019). Effect of Blood Flow Restriction Training on Quadriceps Muscle Strength, Morphology, Physiology, and Knee Biomechanics Before and After Anterior Cruciate Ligament Reconstruction: Protocol for a Randomized Clinical Trial. Physical Therapy, 99(8), 1010-1019. https://doi.org/10.1093/ptj/pzz062Ferraz, R. B., Gualano, B., Rodrigues, R., Kurimori, C. O., Fuller, R., Lima, F. R., DE Sá-Pinto, A. L., & Roschel, H. (2018). Benefits of Resistance Training with Blood Flow Restriction in Knee Osteoarthritis. Medicine and Science in Sports and Exercise, 50(5), 897-905. https://doi.org/10.1249/MSS.0000000000001530Franz, A., Ji, S., Bittersohl, B., Zilkens, C., & Behringer, M. (2022). Impact of a Six-Week Prehabilitation With Blood-Flow Restriction Training on Pre- and Postoperative Skeletal Muscle Mass and Strength in Patients Receiving Primary Total Knee Arthroplasty. Frontiers in Physiology, 13((Franz A., alexander.franz@ukbonn.de) Department of Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany). Embase. https://doi.org/10.3389/fphys.2022.881484Giles, L., Webster, K. E., McClelland, J., & Cook, J. L. (2017). Quadriceps strengthening with and without blood flow restriction in the treatment of patellofemoral pain: A double-blind randomised trial. British Journal of Sports Medicine, 51(23), 1688-1694. https://doi.org/10.1136/bjsports-2016-096329Harper, S. A., Roberts, L. M., Layne, A. S., Jaeger, B. C., Gardner, A. K., Sibille, K. T., Wu, S. S., Vincent, K. R., Fillingim, R. B., Manini, T. M., & Buford, T. W. (2019). Blood-flow restriction resistance exercise for older adults with knee osteoarthritis: A pilot randomized clinical trial. Journal of Clinical Medicine, 8(2). Embase. https://doi.org/10.3390/jcm8020265Higgins, J., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M., & Welch, V. (2023). Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane, 2023. www.training.cochrane.org/handbook.Hughes, L., Paton, B., Haddad, F., Rosenblatt, B., Gissane, C., & Patterson, S. D. (2018). Comparison of the acute perceptual and blood pressure response to heavy load and light load blood flow restriction resistance exercise in anterior cruciate ligament reconstruction patients and non-injured populations. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 33, 54-61. https://doi.org/10.1016/j.ptsp.2018.07.002Hughes, L., Paton, B., Rosenblatt, B., Gissane, C., & Patterson, S. D. (2017). Blood flow restriction training in clinical musculoskeletal rehabilitation: A systematic review and meta-analysis. British Journal of Sports Medicine, 51(13), 1003-1011. Medline. https://doi.org/10.1136/bjsports-2016-097071Hughes, L., Patterson, S. D., Haddad, F., Rosenblatt, B., Gissane, C., McCarthy, D., Clarke, T., Ferris, G., Dawes, J., & Paton, B. (2019). Examination of the comfort and pain experienced with blood flow restriction training during post-surgery rehabilitation of anterior cruciate ligament reconstruction patients: A UK National Health Service trial. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 39, 90-98. https://doi.org/10.1016/j.ptsp.2019.06.014Hughes, L., Rosenblatt, B., Haddad, F., Gissane, C., McCarthy, D., Clarke, T., Ferris, G., Dawes, J., Paton, B., & Patterson, S. D. (2019). Comparing the Effectiveness of Blood Flow Restriction and Traditional Heavy Load Resistance Training in the Post-Surgery Rehabilitation of Anterior Cruciate Ligament Reconstruction Patients: A UK National Health Service Randomised Controlled Trial. Sports Medicine (Auckland, N.Z.), 49(11), 1787-1805. https://doi.org/10.1007/s40279-019-01137-2Instituto Nacional de Salud. (2013). Boletín N°1 ONS (Observatorio Nacional de Salud): Enfermedad cardiovascular principal causa de muerte en Colombia (https://www.ins.gov.co/Direcciones/ONS/Boletines/boletin_web_ONS/referencias.html). Ministerio de Salud y Protección Social.Iversen, E., Røstad, V., & Larmo, A. (2016). Intermittent blood flow restriction does not reduce atrophy following anterior cruciate ligament reconstruction. Journal of Sport and Health Science, 5(1), 115-118. https://doi.org/10.1016/j.jshs.2014.12.005Jack, R. A., Lambert, B. S., Hedt, C. A., Delgado, D., Goble, H., & McCulloch, P. C. (2022). Blood Flow Restriction Therapy Preserves Lower Extremity Bone and Muscle Mass After ACL Reconstruction. Sports Health, (Jack R.A.; Lambert B.S.; Hedt C.A.; Delgado D.; Goble H.; McCulloch P.C.) Orthopedic Biomechanics Research Laboratory, Department of Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, TX, 19417381221101006. Medline. https://doi.org/10.1177/19417381221101006Jensen, K. Y., Jacobsen, M., Schrøder, H. D., Aagaard, P., Nielsen, J. L., Jørgensen, A. N., Boyle, E., Bech, R. D., Rosmark, S., Diederichsen, L. P., & Frandsen, U. (2019). The immune system in sporadic inclusion body myositis patients is not compromised by blood-flow restricted exercise training. Arthritis Research & Therapy, 21(1), 293. https://doi.org/10.1186/s13075-019-2036-2Jønsson, A., Johansen, C., Rolving, N., & Pfeiffer-Jensen, M. (2021). Feasibility and estimated efficacy of blood flow restricted training in female patients with rheumatoid arthritis: A randomized controlled pilot study. Scandinavian Journal of Rheumatology, 50(3), 169-177. https://doi.org/10.1080/03009742.2020.1829701Kambič, T., Novaković, M., Tomažin, K., Strojnik, V., Božič-Mijovski, M., & Jug, B. (2021). Hemodynamic and Hemostatic Response to Blood Flow Restriction Resistance Exercise in Coronary Artery Disease: A Pilot Randomized Controlled Trial. The Journal of Cardiovascular Nursing, 36(5), 507-516. Medline. https://doi.org/10.1097/JCN.0000000000000699Kambic, T., Novakovic, M., Tomazin, K., Strojnik, V., & Jug, B. (2019). Blood flow restriction resistance exercise improves muscle strength and hemodynamics, but not vascular function in coronary artery disease patients: A pilot randomized controlled trial. Frontiers in Physiology, 10(JUN). Embase. https://doi.org/10.3389/fphys.2019.00656Karanasios, S., Korakakis, V., Moutzouri, M., Xergia, S. Α., Tsepis, Ε., & Gioftsos, G. (2022). Low-load resistance training with blood flow restriction is effective for managing lateral elbow tendinopathy: A randomized, sham-controlled trial. The Journal of Orthopaedic and Sports Physical Therapy, (Karanasios S.; Moutzouri M.; Gioftsos G.) Laboratory of Advanced Physiotherapy (LAdPhys), Physiotherapy Department, School of Health and Care Sciences, University of West Attica, Greece, 1-30. Medline. https://doi.org/10.2519/jospt.2022.11211Korakakis, V., Whiteley, R., & Giakas, G. (2018). Low load resistance training with blood flow restriction decreases anterior knee pain more than resistance training alone. A pilot randomised controlled trial. Physical Therapy in Sport : Official Journal of the Association of Chartered Physiotherapists in Sports Medicine, 34, 121-128. https://doi.org/10.1016/j.ptsp.2018.09.007Ladlow, P., Coppack, R. J., Dharm-Datta, S., Conway, D., Sellon, E., Patterson, S. D., & Bennett, A. N. (2018). Low-load resistance training with blood flow restriction improves clinical outcomes in musculoskeletal rehabilitation: A single-blind randomized controlled trial. Frontiers in Physiology, 9(SEP). Embase. https://doi.org/10.3389/fphys.2018.01269Letieri, R. V., Furtado, G. E., Barros, P. M. N., Farias, M. J. A. D., Antunez, B. F., Gomes, B. B., & Teixeira, A. M. M. B. (2019). Effect of 16-Week Blood Flow Restriction Exercise on Functional Fitness in Sarcopenic Women: A Randomized Controlled Trial. International Journal of Morphology, 37(1), 59-64. https://doi.org/10.4067/S0717-95022019000100059Li, N., Yang, J., & Liao, Y. (2023). The effect of blood flow restriction training combined with electrical muscle stimulation on neuromuscular adaptation: A randomized controlled trial. Frontiers in Physiology, 14, 1182249. https://doi.org/10.3389/fphys.2023.1182249Lixandrão, M. E., Roschel, H., Ugrinowitsch, C., Miquelini, M., Alvarez, I. F., & Libardi, C. A. (2019). Blood-Flow Restriction Resistance Exercise Promotes Lower Pain and Ratings of Perceived Exertion Compared With Either High- or Low-Intensity Resistance Exercise Performed to Muscular Failure. Journal of Sport Rehabilitation, 28(7), 706-710. https://doi.org/10.1123/jsr.2018-0030Londoño, J., Peláez Ballestas, I., Cuervo, F., Angarita, I., Giraldo, R., Rueda, J. C., Ballesteros, J. G., Baquero, R., Forero, E., Cardiel, M., Saldarriaga, E., Vásquez, A., Arias, S., Valero, L., González, C., Ramírez, J., Toro, C., & Santos, A. M. (2018). Prevalencia de la enfermedad reumática en Colombia, según estrategia COPCORD-Asociación Colombiana de Reumatología. Estudio de prevalencia de enfermedad reumática en población colombiana mayor de 18 años. Revista Colombiana de Reumatología, 25(4), 245-256. https://doi.org/10.1016/j.rcreu.2018.08.003Loprinzi, P. D. (2016). Multimorbidity, cognitive function, and physical activity. AGE, 38(1), 8. https://doi.org/10.1007/s11357-016-9874-5Madarame, H., Kurano, M., Fukumura, K., Fukuda, T., & Nakajima, T. (2013). Haemostatic and inflammatory responses to blood flow-restricted exercise in patients with ischaemic heart disease: A pilot study. Clinical Physiology and Functional Imaging, 33(1), 11-17. https://doi.org/10.1111/j.1475-097X.2012.01158.xMahmoud, W. S., Osailan, A., Ahmed, A. S., Elnaggar, R. K., & Radwan, N. L. (2021). Optimal parameters of blood flow restriction and resistance training on quadriceps strength and cross-sectional area and pain in knee osteoarthritis. Isokinetics and Exercise Science, 29(4), 393-402. Embase. https://doi.org/10.3233/IES-200235Majors, I. B., Mears, S. C., Oholendt, C. K., Hargett, N. A., Barnes, C. L., & Stambough, J. B. (2022). Does Blood Flow Restriction Therapy Improve Leg Strength in Patients With a Painful Total Knee Arthroplasty? The Journal of Arthroplasty, 37(6), 1064-1068. https://doi.org/10.1016/j.arth.2022.02.021Mason, J. S., Crowell, M. S., Brindle, R. A., Dolbeer, J. A., Miller, E. M., Telemeco, T. A., & Goss, D. L. (2022). The Effect of Blood Flow Restriction Training on Muscle Atrophy Following Meniscal Repair or Chondral Restoration Surgery in Active Duty Military: A Randomized Controlled Trial. Journal of Sport Rehabilitation, 31(1), 77-84. Medline. https://doi.org/10.1123/jsr.2020-0518Mason, M. J. S., Owens, J. G., & Brown, L. W. J. (2018). Blood Flow Restriction Training: Current and Future Applications for the Rehabilitation of Musculoskeletal Injuries. Techniques in Orthopaedics, 33(2), 71-71. https://doi.org/10.1097/BTO.0000000000000301May, A. K., Brandner, C. R., & Warmington, S. A. (2017). Hemodynamic responses are reduced with aerobic compared with resistance blood flow restriction exercise. Physiological Reports, 5(3). https://doi.org/10.14814/phy2.13142McGuinness, L. A., & Higgins, J. P. T. (2020). Risk-of-bias VISualization (robvis): An R package and Shinyweb app for visualizing risk-of-bias assessments. Research Synthesis Methods. 10.1002/jrsm.1411Miller, B. C., Tirko, A. W., Shipe, J. M., Sumeriski, O. R., & Moran, K. (2021). The Systemic Effects of Blood Flow Restriction Training: A Systematic Review. International Journal of Sports Physical Therapy, 16(4). https://doi.org/10.26603/001c.25791Nagy-Pénzes, G., Vincze, F., & Bíró, É. (2022). A School Intervention’s Impact on Adolescents’ Health-Related Knowledge and Behavior. Frontiers in Public Health, 10, 822155. https://doi.org/10.3389/fpubh.2022.822155National Cancer Institute. (2023). Cardiovascular Disease Definition. https://www.cancer.gov/espanol/publicaciones/diccionarios/diccionario-cancer/def/enfermedad-cardiovascularNatsume, T., Ozaki, H., Saito, A. I., Abe, T., & Naito, H. (2015). Effects of Electrostimulation with Blood Flow Restriction on Muscle Size and Strength. Medicine & Science in Sports & Exercise, 47(12), 2621-2627. https://doi.org/10.1249/MSS.0000000000000722Nielsen, J. L., Frandsen, U., Prokhorova, T., Bech, R. D., Nygaard, T., Suetta, C., & Aagaard, P. (2017). Delayed Effect of Blood Flow–restricted Resistance Training on Rapid Force Capacity. Medicine & Science in Sports & Exercise, 49(6), 1157-1167. https://doi.org/10.1249/MSS.0000000000001208Ogawa, H., Nakajima, T., Shibasaki, I., Nasuno, T., Kaneda, H., Katayanagi, S., Ishizaka, H., Mizushima, Y., Uematsu, A., Yasuda, T., Yagi, H., Toyoda, S., Hortobágyi, T., Mizushima, T., Inoue, T., & Fukuda, H. (2021). Low-intensity resistance training with moderate blood flow restriction appears safe and increases skeletal muscle strength and size in cardiovascular surgery patients: A pilot study. Journal of Clinical Medicine, 10(3), 1-13. Embase. https://doi.org/10.3390/jcm10030547Omer, K., Nermin, G., Ali, A., Mehmet, A., Unal, D., Sezen, K. S., & Hakan, K. (2017). Lesão de isquemia‐reperfusão induzida por torniquete: Comparação dos efeitos antioxidantes de propofol e cetamina em doses baixas. Brazilian Journal of Anesthesiology, 67(3), 246-250. https://doi.org/10.1016/j.bjan.2016.10.007Owen, N., Healy, G. N., Dempsey, P. C., Salmon, J., Timperio, A., Clark, B. K., Goode, A. D., Koorts, H., Ridgers, N. D., Hadgraft, N. T., Lambert, G., Eakin, E. G., Kingwell, B. A., & Dunstan, D. W. (2020). Sedentary Behavior and Public Health: Integrating the Evidence and Identifying Potential Solutions. Annual Review of Public Health, 41(1), 265-287. https://doi.org/10.1146/annurev-publhealth-040119-094201Patterson, S. D., Hughes, L., Head, P., Warmington, S., & Brandner, C. (2017). Blood flow restriction training: A novel approach to augment clinical rehabilitation: how to do it. British Journal of Sports Medicine, 51(23), 1648-1649. https://doi.org/10.1136/bjsports-2017-097738Patterson, S. D., Hughes, L., Warmington, S., Burr, J., Scott, B. R., Owens, J., Abe, T., Nielsen, J. L., Libardi, C. A., Laurentino, G., Neto, G. R., Brandner, C., Martin-Hernandez, J., & Loenneke, J. (2019). Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety. Frontiers in Physiology, 10, 533. https://doi.org/10.3389/fphys.2019.00533Prince, S. A., Gresty, K. M., Reed, J. L., Wright, E., Tremblay, M. S., & Reid, R. D. (2014). Individual, social and physical environmental correlates of sedentary behaviours in adults: A systematic review protocol.Przkora, R., Sibille, K., Victor, S., Meroney, M., Leeuwenburgh, C., Gardner, A., Vasilopoulos, T., & Parvataneni, H. K. (2021). Blood flow restriction exercise to attenuate postoperative loss of function after total knee replacement: A randomized pilot study. European Journal of Translational Myology, 31(3). Embase. https://doi.org/10.4081/ejtm.2021.9932Resolución No 8430 de Octubre 4 de 1993, Pub. L. No. Resolución 8430 de 1993. chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/DE/DIJ/RESOLUCION-8430-DE-1993.PDFRodrigues R; Ferraz RB; Kurimori CO; Guedes LK; Lima FR; de Sa-Pinto AL; Gualano B; Roschel H. (2020). Low-load resistance training with blood flow restriction increases muscle function, mass and functionality in women with rheumatoid arthritis [with consumer summary]. Arthritis Care & Research 2020 Jun;72(6):787-797. Downloaded from PEDro http://www.pedro.org.au.Saraf, A., Goyal, M., & Goyal, K. (2022). Blood Flow Restriction Training-An Overview and Implication in New Generation Physical Therapy: A Narrative Review. Journal of Lifestyle Medicine, 12(2), 63-68. https://doi.org/10.15280/jlm.2022.12.2.63Sato, Y. (2005). The history and future of KAATSU Training. International Journal of KAATSU Training Research, 1(1), 1-5. https://doi.org/10.3806/ijktr.1.1Segal, N. A., Williams, G. N., Davis, M. C., Wallace, R. B., & Mikesky, A. E. (2015). Efficacy of Blood Flow–Restricted, Low-Load Resistance Training in Women with Risk Factors for Symptomatic Knee Osteoarthritis. PM&R, 7(4), 376-384. https://doi.org/10.1016/j.pmrj.2014.09.014Sgromolo, N. M., Cancio, J. M., & Rhee, P. C. (2020). Safety and Efficacy of Blood Flow Restriction Therapy after Operative Management of Distal Radius Fractures: A Randomized Controlled Study. Journal of Wrist Surgery, 09(04), 345-352. https://doi.org/10.1055/s-0040-1712504Silva, I. B., Barbosa, J. B. N., Araújo, A. X. P., & Marinho, P. E. M. (2021). Effect of an exercise program with blood flow restriction on the muscular strength of patients with chronic kidney disease: A randomized clinical trial. Journal of Bodywork and Movement Therapies, 28, 187-192. https://doi.org/10.1016/j.jbmt.2021.06.022Sugawara, J., Tomoto, T., & Tanaka, H. (2015). Impact of leg blood flow restriction during walking on central arterial hemodynamics. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 309(7), R732-R739. https://doi.org/10.1152/ajpregu.00095.2015Tramer, J. S., Khalil, L. S., Jildeh, T. R., Abbas, M. J., McGee, A., Lau, M. J., Moutzouros, V., & Okoroha, K. R. (2022). Blood Flow Restriction Therapy for Two Weeks Prior to Anterior Cruciate Ligament Reconstruction Did not Impact Quadriceps Strength Compared to Standard Therapy. Arthroscopy: The Journal of Arthroscopic & Related Surgery. https://doi.org/10.1016/j.arthro.2022.06.027Vanwye, W. R., & Weatherholt, A. M. (2017). Blood Flow Restriction Training: Implementation into Clinical Practice.Villamil Parra, W. A. V. (2016). REVISIÓN SISTEMÁTICA DE LA EFICACIA DEL EJERCICIO FÍSICO EN PACIENTES ADULTOS HOSPITALIZADOS EN UCI. Universidad Nacional de Colombia - Sede Bogotá.Wernbom, M., Schoenfeld, B. J., Paulsen, G., Bjørnsen, T., Cumming, K. T., Aagaard, P., Clark, B. C., & Raastad, T. (2020). Commentary: Can Blood Flow Restricted Exercise Cause Muscle Damage? Commentary on Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety. Frontiers in Physiology, 11, 243. https://doi.org/10.3389/fphys.2020.00243Zhang, X., Xie, W., Chen, L., Xu, G., Wu, L., Li, Y., & Wu, Y. (2022). Blood Flow Restriction Training for the Intervention of Sarcopenia: Current Stage and Future Perspective. Frontiers in Medicine, 9, 894996. https://doi.org/10.3389/fmed.2022.894996Zhao Y; Zheng Y; Ma X; Qiang L; Lin A; Zhou M. (2022). Low-intensity resistance exercise combined with blood flow restriction is more conducive to regulate blood pressure and autonomic nervous system in hypertension patients-compared with high-intensity and low-intensity resistance exercise. Frontiers in Physiology 2022 Apr20;13(833809):Epub. Downloaded from PEDro http://www.pedro.org.au.EstudiantesGrupos comunitariosInvestigadoresMaestrosPúblico generalLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/86488/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL1018478394.2024.pdf1018478394.2024.pdfTesis de maestría en Fisioterapia del deporte y la actividad físicaapplication/pdf2905124https://repositorio.unal.edu.co/bitstream/unal/86488/2/1018478394.2024.pdf9da4e266b69eb906ac29f0a7ac7117a3MD52unal/86488oai:repositorio.unal.edu.co:unal/864882024-07-16 15:55:22.562Repositorio Institucional Universidad Nacional de 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