Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá

ilustraciones, diagramas, tablas

Autores:
Ramírez Pimiento, Juan David
Tipo de recurso:
Fecha de publicación:
2024
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/86498
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/86498
https://repositorio.unal.edu.co/
Palabra clave:
610 - Medicina y salud::612 - Fisiología humana
Hematócrito
Peso Corporal
Volumen Plasmático
Hematocrit
Body Weight
Plasma Volume
Ayuno
Estado de hipohidratación del organismo
Deshidratación
Periodo preoperatorio
Oliguria
Fasting
Organism hypohydration status
Dehydration
Preoperative period
Oliguria
Rights
openAccess
License
Atribución-CompartirIgual 4.0 Internacional
id UNACIONAL2_8bf64d25a652e0f2108fc6e13e231387
oai_identifier_str oai:repositorio.unal.edu.co:unal/86498
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá
dc.title.translated.eng.fl_str_mv Fasting And Hypohydration in A Period Of 24 Hours, A Quasi-Experimental Pilot in Natural Conditions in Volunteers In Bogotá
title Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá
spellingShingle Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá
610 - Medicina y salud::612 - Fisiología humana
Hematócrito
Peso Corporal
Volumen Plasmático
Hematocrit
Body Weight
Plasma Volume
Ayuno
Estado de hipohidratación del organismo
Deshidratación
Periodo preoperatorio
Oliguria
Fasting
Organism hypohydration status
Dehydration
Preoperative period
Oliguria
title_short Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá
title_full Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá
title_fullStr Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá
title_full_unstemmed Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá
title_sort Ayuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en Bogotá
dc.creator.fl_str_mv Ramírez Pimiento, Juan David
dc.contributor.advisor.none.fl_str_mv Diaztagle Fernández, Juan José
dc.contributor.author.none.fl_str_mv Ramírez Pimiento, Juan David
dc.contributor.orcid.spa.fl_str_mv Ramírez-Pimiento, Juan David [https://orcid.org/0000-0003-2259-6338]
dc.subject.ddc.spa.fl_str_mv 610 - Medicina y salud::612 - Fisiología humana
topic 610 - Medicina y salud::612 - Fisiología humana
Hematócrito
Peso Corporal
Volumen Plasmático
Hematocrit
Body Weight
Plasma Volume
Ayuno
Estado de hipohidratación del organismo
Deshidratación
Periodo preoperatorio
Oliguria
Fasting
Organism hypohydration status
Dehydration
Preoperative period
Oliguria
dc.subject.decs.spa.fl_str_mv Hematócrito
Peso Corporal
Volumen Plasmático
dc.subject.decs.eng.fl_str_mv Hematocrit
Body Weight
Plasma Volume
dc.subject.proposal.spa.fl_str_mv Ayuno
Estado de hipohidratación del organismo
Deshidratación
Periodo preoperatorio
Oliguria
dc.subject.proposal.eng.fl_str_mv Fasting
Organism hypohydration status
Dehydration
Preoperative period
Oliguria
description ilustraciones, diagramas, tablas
publishDate 2024
dc.date.accessioned.none.fl_str_mv 2024-07-16T23:22:18Z
dc.date.available.none.fl_str_mv 2024-07-16T23:22:18Z
dc.date.issued.none.fl_str_mv 2024
dc.type.spa.fl_str_mv Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/TM
status_str acceptedVersion
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/86498
dc.identifier.instname.spa.fl_str_mv Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv https://repositorio.unal.edu.co/
url https://repositorio.unal.edu.co/handle/unal/86498
https://repositorio.unal.edu.co/
identifier_str_mv Universidad Nacional de Colombia
Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.references.spa.fl_str_mv Romit JJA, van de Mortel T. Ritualistic preoperative fasting: Is it still occurring and what can we do about it? Acorn. 2011;24(1):14–20. [Internet 12/2023]; Available from: Https://research-repository.griffith.edu.au/bitstream/10072/54758/3/90088_1.pdf
Bilehjani E, Fakhari S, Yavari S, Panahi JR, Afhami M, Nagipour B, et al. Adjustment of Preoperative Fasting Guidelines for Adult Patients Undergoing Elective Surgery. Open J Intern Med. 2015;05(04):115–8. Https://doi.org/10.4236/ojim.2015.54016
Gómez A. Líquidos y electrolitos en anestesia. Rev Col Anest. 1984;(179).
Liska D, Mah E, Brisbois T, Barrios PL, Baker LB, Spriet LL. Narrative Review of Hydration and Selected Health Outcomes in the General Population. Nutrients. 2019 Jan 1;11(1):70. Https://doi.org/10.3390/nu11010070
Petri NM, Dropulić N, Kardum G. Effects of Voluntary Fluid Intake Deprivation on Mental and Psychomotor Performance. Croat Med J. 2006;47(6):855. Available from: Https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/17167858/
Miller RD, Eriksson LI, Fleisher LA, Wiener-Kronish JP, Cohen NH, Young WL. Miller’s Anesthesia. Elsevier Health Sciences; 2014. 4094 p.
Khoyratty S, Din A, Spendlove R, Teehan M, Arhi C, Modi BN, et al. The Impact of Discussing Preoperative Fasting with Patients. J Perioper Pract. 2011 Aug 1;21(8):284–6. Https://doi.org/10.1177/175045891102100805
Connolly J, Cunningham AJ. Preoperative fasting and administration of regular medications in adult patients presenting for elective surgery. Has new evidence changed clinical practice? Eur J Anaesthesiol. 2000 Apr;17(4):219– 20. Https://doi.org/10.1046/j.1365-2346.2000.00603.x
Jacob M, Chappell D. Effects of perioperative fasting on haemodynamics and intravascular volumes. Best Pract Res Clin Anaesthesiol. 2012 Dec;26(4):421–30. Https://doi.org/10.1016/j.bpa.2012.10.002
Watso JC, Babcock MC, Robinson AT, Migdal KU, Wenner MM, Stocker SD, et al. Water deprivation does not augment sympathetic or pressor responses to sciatic afferent nerve stimulation in rats or to static exercise in humans. J Appl Physiol. 2019 Jul 1;127(1):235–45. Https://doi.org/10.1152/japplphysiol.00005.2019
Danielsson EJD, Lejbman I, Åkeson J. Fluid deficits during prolonged overnight fasting in young healthy adults. Acta Anaesthesiol Scand. 2019 Feb 21;63(2):195–9. Https://doi.org/10.1111/aas.13254
Chacon MM, Markin NW. Part of the Great Fluid Debate—Are Fasting Patients Hypovolemic? J Cardiothorac Vasc Anesth. 2019 Sep;33(9):2428–30. Https://doi.org/10.1053/j.jvca.2019.03.032
Park KS, Yoo KY. Role of vasopressin in current anesthetic practice. Korean J Anesthesiol. 2017;70(3):245. Https://doi.org/10.4097/kjae.2017.70.3.245
Hall JE, Hall ME. Guyton and Hall: Textbook of Medical Physiology. 14th ed. Elsevier. Elsevier; 2021.
Koshimizu T aki, Nakamura K, Egashira N, Hiroyama M, Nonoguchi H, Tanoue A. Vasopressin V1a and V1b Receptors: From Molecules to Physiological Systems. Physiol Rev. 2012 Oct;92(4):1813–64. Https://doi.org/10.1152/physrev.00035.2011
Rabbitts JA, Charkoudian N. Sympathetic nervous system and volume-regulatory hormones: interactions during dehydration. Physiol News. 2011 Jan 1;(Winter 2010):39–40. Https://doi.org/10.36866/pn.81.39
James LJ, Shirreffs SM. Fluid and Electrolyte Balance During 24-Hour Fluid and/or Energy Restriction. Int J Sport Nutr Exerc Metab. 2013 Dec;23(6):545–53. Https://doi.org/10.1123/ijsnem.23.6.545
Oliver SJ, Laing SJ, Wilson S, Bilzon JLJ, Walsh N. Endurance Running Performance after 48 h of Restricted Fluid and/or Energy Intake. Med Sci Sport Exerc. 2007 Feb;39(2):316–22. Https://doi.org/10.1249/01.mss.0000241656.22629.57
Fawcett WJ, Thomas M. Pre-operative fasting in adults and children: clinical practice and guidelines. Anaesthesia. 2019 Jan;74(1):83–8. Https://doi.org/10.1111/anae.14500
American Society of Anesthesiologists. Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures. Anesthesiology. 2017 Mar 1;126(3):376–93. Https://doi.org/10.1097/ALN.0000000000001452
Gustafsson UO, Scott MJ, Hubner M, Nygren J, Demartines N, Francis N, et al. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018. World J Surg. 2019 Mar 13;43(3):659–95. Https://doi.org/10.1007/s00268-018-4844-y
Batchelor TJP, Rasburn NJ, Abdelnour-Berchtold E, Brunelli A, Cerfolio RJ, Gonzalez M, et al. Guidelines for enhanced recovery after lung surgery: recommendations of the Enhanced Recovery After Surgery (ERAS®) Society and the European Society of Thoracic Surgeons (ESTS). Eur J Cardio-Thoracic Surg. 2019 Jan 1;55(1):91–115. Https://doi.org/10.1093/ejcts/ezy301
Smith I, Kranke P, Murat I, Smith A, OʼSullivan G, Sreide E, et al. Perioperative fasting in adults and children. Eur J Anaesthesiol. 2011 Aug;28(8):556–69. Https://doi.org/10.1097/EJA.0b013e3283495ba1
Morrison CE, Ritchie-McLean S, Jha A, Mythen M. Two hours too long: time to review fasting guidelines for clear fluids. Br J Anaesth. 2020 Apr 1;124(4):363–6. Https://doi.org/10.1016/j.bja.2019.11.036
Green SM, Leroy PL, Roback MG, Irwin MG, Andolfatto G, Babl FE, et al. An international multidisciplinary consensus statement on fasting before procedural sedation in adults and children. Anaesthesia. 2020 Mar 2;75(3):374–85. Https://doi.org/10.1111/anae.14892
Elliott E, Isserman R, Stricker P, Yaddanapudi S, Subramanyam R. Fasting for anaesthesia: Less is more! Indian J Anaesth. 2020 Feb 1;64(2):87. Https://doi.org/10.4103/ija.IJA_936_19
Thomas M, Morrison C, Newton R, Schindler E. Consensus statement on clear fluids fasting for elective pediatric general anesthesia. Pediatr Anesth. 2018 May 1;28(5):411–4. Https://doi.org/10.1111/pan.13370
Frykholm P, Schindler E, Sümpelmann R, Walker R, Weiss M. Preoperative fasting in children: review of existing guidelines and recent developments. Br J Anaesth. 2018 Mar 1;120(3):469–74. Https://doi.org/10.1016/j.bja.2017.11.080
Frykholm P, Disma N, Andersson H, Beck C, Bouvet L, Cercueil E, et al. Pre-operative fasting in children. Eur J Anaesthesiol. 2022 Jan;39(1):4–25. Https://doi.org/10.1097/EJA.0000000000001599
Beck CE, Rudolp D, Becke-Jakob K, Schindler E, Etspüler A, Trapp A, et al. Real fasting times and incidence of pulmonary aspiration in children: Results of a German prospective multicenter observational study. Pediatr Anesth. 2019 Oct 1;29(10):1040–5. Https://doi.org/10.1111/PAN.13725
Jacob M, Chappell D, Conzen P, Finsterer U, Rehm M. Blood volume is normal after pre‐operative overnight fasting. Acta Anaesthesiol Scand. 2008 Apr 13;52(4):522–9. Https://doi.org/10.1111/j.1399-6576.2008.01587.x
Abebe WA, Rukewe A, Bekele NA, Stoffel M, Nicoh M, Zeberga J. Preoperative fasting times in elective surgical patients at a referral Hospital in Botswana. Pan Afr Med J. 2016;23:1–8. Https://doi.org/10.11604/pamj.2016.23.102.8863
Zia F, Cosic L, Wong A, Levin A, Lu P, Mitchell C, et al. Effects of a short message service (SMS) by cellular phone to improve compliance with fasting guidelines in patients undergoing elective surgery: a retrospective observational study. BMC Health Serv Res. 2021 Dec 6;21(1):27. Https://doi.org/10.1186/s12913-020-06039-y
El-Sharkawy AM, Daliya P, Lewis-Lloyd C, Adiamah A, Malcolm FL, Boyd-Carson H, et al. Fasting and surgery timing (FaST) audit. Clin Nutr. 2021 Mar;40(3):1405–12. Https://doi.org/10.1016/j.clnu.2020.08.033
Al‐Robeye AM, Barnard AN, Bew S. Thirsty work: Exploring children’s experiences of preoperative fasting. Thomas M, editor. Pediatr Anesth. 2020 Jan 19;30(1):43–9. Https://doi.org/10.1111/pan.13759
Isserman R, Elliott E, Subramanyam R, Kraus B, Sutherland T, Madu C, et al. Quality improvement project to reduce pediatric clear liquid fasting times prior to anesthesia. Veyckemans F, editor. Pediatr Anesth. 2019 Jul 2;29(7):698– 704. Https://doi.org/10.1111/pan.13661
Cestonaro T, Madalozzo Schieferdecker ME, Thieme RD, Neto Cardoso J, Ligocki Campos AC. The reality of the surgical fasting time in the era of the ERAS protocol. Nutr Hosp. 2014 Feb 1;29(2):437–43. Https://doi.org/10.3305/nh.2014.29.2.7025
Ramos-Amézquita MH. Relación entre el ayuno preoperatorio prolongado y la sensación de malestar general en cirugía ambulatoria [Internet]. Universidad Nacional de Colombia; 2019. Available from: Https://repositorio.unal.edu.co/handle/unal/69031
Rangel-Miranda FL. Ayuno prolongado y riesgo de náuseas y vómito postoperatorio: estudio de cohorte [Internet]. Universidad Autónoma de Bucaramanga; 2018. Available from: Https://repository.unab.edu.co/handle/20.500.12749/1630
Crenshaw JT, Winslow EH. Preoperative Fasting: Old Habits Die Hard. Am J Nurs. 2002 May;102(5):36–44. Https://doi.org/10.1097/00000446-200205000-00033
Maltby JR. Fasting from midnight – the history behind the dogma. Best Pract Res Clin Anaesthesiol. 2006 Sep;20(3):363–78. Https://doi.org/10.1016/j.bpa.2006.02.001
Chappell D, Jacob M, Hofmann-Kiefer K, Conzen P, Rehm M. A Rational Approach to Perioperative Fluid Management. Anesthesiology. 2008 Oct 1;109(4):723–40. Https://doi.org/10.1097/ALN.0b013e3181863117
Tsukamoto M, Hitosugi T, Yokoyama T. Influence of Fasting Duration on Body Fluid and Hemodynamics. Anesth Prog. 2017 Dec 1;64(4):226–9. Https://doi.org/10.2344/anpr-65-01-01
Muller L, Brière M, Bastide S, Roger C, Zoric L, Seni G, et al. Preoperative fasting does not affect haemodynamic status: a prospective, non-inferiority, echocardiography study. Br J Anaesth. 2014 May;112(5):835–41. Https://doi.org/10.1093/bja/aet478
Field RR, Mai T, Hanna S, Harrington B, Calderon MD, Rinehart J. Lack of impact of nil-per-os (NPO) time on goal- directed fluid delivery in first case versus afternoon case starts: A retrospective cohort study. BMC Anesthesiol. 2019 Oct 27;19(1):1–9. Https://doi.org/10.1186/S12871-019-0864-X/FIGURES/3
Kiefer N, Rode C, Baehner T, Zenker S, Hoeft A. Fasting before elective surgery does not result in hypovolaemia. Eur J Anaesthesiol. 2018 Jul;35(7):539–40. Https://doi.org/10.1097/EJA.0000000000000811
Bundgaard‐Nielsen M, Jørgensen CC, Kehlet H, Secher NH. Normovolemia defined according to cardiac stroke volume in healthy supine humans. Clin Physiol Funct Imaging. 2010 Sep 10;30(5):318–22. Https://doi.org/10.1111/j.1475-097X.2010.00944.x
Geelen G, Greenleaf JE, Keil LC. Drinking-induced plasma vasopressin and norepinephrine changes in dehydrated humans. J Clin Endocrinol Metab. 1996 Jun;81(6):2131–5. Https://doi.org/10.1210/jcem.81.6.8964840
Rehm M, Haller M, Orth V, Kreimeier U, Jacob M, Dressel H, et al. Changes in Blood Volume and Hematocrit during Acute Preoperative Volume Loading with 5% Albumin or 6% Hetastarch Solutions in Patients before Radical Hysterectomy. Anesthesiology. 2001 Oct 1;95(4):849–56. Https://doi.org/10.1097/00000542-200110000-00011
Corney RA, Horina A, Sunderland C, James LJ. Effect of hydration status and fluid availability on ad-libitum energy intake of a semi-solid breakfast. Appetite. 2015;91:399–404. Https://doi.org/10.1016/j.appet.2015.04.075
Mosek A, Korczyn AD. Fasting Headache, Weight Loss, and Dehydration. Headache J Head Face Pain. 1999 Mar;39(3):225–7. Https://doi.org/10.1046/j.1526-4610.1999.3903225.x
Tortora GJ, Derrickson B. Principios de Anatomía y Fisiología. 13th ed. Panamericana; 2011.
Gómez Castilla AM. Correlación entre el tiempo de ayuno preoperatorio y el descenso intraoperatorio de la temperatura central en adultos sometidos a cirugía no cardiaca. 2018; Available from: Https://repositorio.unal.edu.co/handle/unal/63466
Salvat Editores, editor. Diccionario Terminológico de Ciencias Médicas. 12th ed. España: Salvat; 1984.
Valero J, editor. Enciclopedia Salvat de Ciencias Médicas. 1st ed. Barcelona, España: Salvat; 1955.
Maughan RJ, Shirreffs SM. Hydration and performance during Ramadan. J Sports Sci. 2012 Jul;30(sup1):S33–41. Https://doi.org/10.1080/02640414.2012.688140
Leiper JB, Molla AM, Molla AM. Effects on health of fluid restriction during fasting in Ramadan. Eur J Clin Nutr. 2003 Dec 1;57(S2):S30–8. Https://doi.org/10.1038/sj.ejcn.1601899
Welton S, Minty R, O’Driscoll T, Willms H, Poirier D, Madden S, et al. Intermittent fasting and weight loss: Systematic review. Can Fam Physician. 2020 Feb 1;66(2):117. [Internet 05/2022]; Available from: Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021351/
Hamdan M, Pucket Y. Total Parenteral Nutrition - StatPearls - NCBI Bookshelf [Internet]. StatPearls Publishing. 2022. [Internet 05/2022]; Available from: Https://www.ncbi.nlm.nih.gov/books/NBK559036/
Herbert G, Perry R, Andersen HK, Atkinson C, Penfold C, Lewis SJ, et al. Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of hospital stay and postoperative complications. Cochrane Database Syst Rev. 2019 Jul 22;2019(7). Https://doi.org/10.1002/14651858.CD004080.pub4
Yang D, He W, Zhang S, Chen H, Zhang C, He Y. Fast-Track Surgery Improves Postoperative Clinical Recovery and Immunity After Elective Surgery for Colorectal Carcinoma: Randomized Controlled Clinical Trial. World J Surg. 2012 Aug 24;36(8):1874–80. Https://doi.org/10.1007/s00268-012-1606-0
Sawka MN, Cheuvront SN, Carter R. Human Water Needs. Nutr Rev. 2005 Jun;63:S30–9. Https://doi.org/10.1111/j.1753-4887.2005.tb00152.x
Armstrong LE. Assessing Hydration Status: The Elusive Gold Standard. J Am Coll Nutr. 2007 Oct;26(sup5):575S-584S. Https://doi.org/10.1080/07315724.2007.10719661
Lizarralde-Palacios E, Gutiérrez-Macías A, Martínez-Ortiz-de-Zárate M. Alteraciones de la termorregulación. Emergencias. 2000;12(3):192–207. Available from: Http://emergencias.portalsemes.org/numeros- anteriores/volumen-12/numero-3/alteraciones-de-la-termorregulacion/
Sawka M, Pandolf K. Effects of body water loss on physiological function and exercise performance. In: Lamb DR, Murray R, Gisolfi C V., editors. Fluid Homeostasis During Exercise. Benchmark Press; 1990.
Oppliger RA, Bartok C. Hydration Testing of Athletes. Sport Med. 2002;32(15):959–71. Https://doi.org/10.2165/00007256-200232150-00001
Johansen LB, Gharib C, Allevard AM, Sigaudo D, Christensen NJ, Drummer C, et al. Haematocrit, plasma volume and noradrenaline in humans during simulated weightlessness for 42 days. Clin Physiol. 1997 Mar;17(2):203–10. Https://doi.org/10.1046/j.1365-2281.1997.02626.x
Maw GJ. Human body-fluid distribution: postural, thermal, and exercise stress [Internet]. 1994. [Internet 05/2021]; Available from: Http://ro.uow.edu.au/theses/1086
Stachenfeld NS, Gleim GW, Zabetakis PM, Nicholas JA. Fluid balance and renal response following dehydrating exercise in well-trained men and women. Eur J Appl Physiol Occup Physiol. 1996 Mar;72–72(5–6):468–77. Https://doi.org/10.1007/BF00242277
Nose H, Mack GW, Shi XR, Nadel ER. Shift in body fluid compartments after dehydration in humans. J Appl Physiol. 1988 Jul 1;65(1):318–24. Https://doi.org/10.1152/jappl.1988.65.1.318
Owen JA, Fortes MB, Ur Rahman S, Jibani M, Walsh NP, Oliver SJ. Hydration Marker Diagnostic Accuracy to Identify Mild Intracellular and Extracellular Dehydration. Int J Sport Nutr Exerc Metab. 2019 Nov 1;29(6):604–11. Https://doi.org/10.1123/ijsnem.2019-0022
Dill DB, Costill DL. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol. 1974 Aug;37(2):247–8. Https://doi.org/10.1152/jappl.1974.37.2.247
Melin B, Jimenez C, Savourey G, Bittel J, Cottet-Emard JM, Pequignot JM, et al. Effects of hydration state on hormonal and renal responses during moderate exercise in the heat. Eur J Appl Physiol. 1997 Sep 1;76(4):320–7. Https://doi.org/10.1007/s004210050255
Jimenez C, Melin B, Koulmann N, Allevard AM, Launay JC, Savourey G. Plasma volume changes during and after acute variations of body hydration level in humans. Eur J Appl Physiol Occup Physiol. 1999 May;80(1):1–8. Https://doi.org/10.1007/s004210050550
Sawka MN. Physiological consequences of hypohydration. Med Sci Sport Exerc. 1992 Jun;24(6):657???670. Https://doi.org/10.1249/00005768-199206000-00008
Rabbitts JA, Strom NA, Sawyer JR, Curry TB, Dietz NM, Roberts SK, et al. Influence of endogenous angiotensin II on control of sympathetic nerve activity in human dehydration. J Physiol. 2009 Nov 15;587(22):5441–9. Https://doi.org/10.1113/jphysiol.2009.176693
Hahn R, Andrijauskas A, Drobin D, Svensén C, Ivaškevičius J. A volume loading test for the detection of hypovolemia and dehydration. Medicina (B Aires). 2008 Sep 28;44(12):953. Https://doi.org/10.3390/medicina44120119
Hope A, Aanderud L, Aakvaag A. Dehydration and body fluid-regulating hormones during sweating in warm (38°C) fresh- and seawater immersion. J Appl Physiol. 2001 Oct 1;91(4):1529–34. Https://doi.org/10.1152/jappl.2001.91.4.1529
Arnaoutis G, Kavouras SA, Stratakis N, Likka M, Mitrakou A, Papamichael C, et al. The effect of hypohydration on endothelial function in young healthy adults. Eur J Nutr. 2017 Apr 10;56(3):1211–7. Https://doi.org/10.1007/s00394-016-1170-8
Desborough JP. The stress response to trauma and surgery. Br J Anaesth. 2000 Jul;85(1):109–17. Https://doi.org/10.1093/bja/85.1.109
Prete A, Yan Q, Al-Tarrah K, Akturk HK, Prokop LJ, Alahdab F, et al. The cortisol stress response induced by surgery: A systematic review and meta-analysis. Clin Endocrinol (Oxf). 2018 Nov;89(5):554–67. Https://doi.org/10.1111/cen.13820
Snow J. On Chloroform and Other Anaesthetics: Their Action and Administration. Br J Anaesth. 1858 May 1;30(5):247–52. Https://doi.org/10.1093/bja/30.5.247
Knight PR, Bacon DR. An Unexplained DeathHannah Greener and Chloroform. Anesthesiology. 2002 May 1;96(5):1250–3. Https://doi.org/10.1097/00000542-200205000-00030
Sutherland AD, Stock JG, Davies JM. Effects Of Preoperative Fasting On Morbidity And Gastric Contents In Patients Undergoing Day-Stay Surgery. Br J Anaesth. 1986 Aug;58(8):876–8. Https://doi.org/10.1093/bja/58.8.876
Ho YH. Contemporary Issues in Colorectal Surgical Practice [Internet]. Croatia: IntechOpen; 2012. [Internet 07/2021]; Available from: Https://books.google.com.co/books?id=e1WRDwAAQBAJ
Barash PG, Cahalan MK, Cullen BF, Stock MC, Stoelting RK, Ortega R, editors. Clinical Anesthesia. 7th ed. USA: LIPPINCOTT WILLIAMS & WILKINS; 2013.
Mendelson CL. The Aspiration of Stomach Contents into the Lungs During Obstetric Anesthesia. Am J Obstet Gynecol. 1946 Aug 1;52(2):191–205. Https://doi.org/10.1016/S0002-9378(16)39829-5
Royal College of Nursing. Perioperative fasting in adults and children An RCN guideline for the multidisciplinary team (full version) [Internet]. 2005. [Internet 07/2021]; Available from: Https://media.gosh.nhs.uk/documents/RCN_Perioperative_Fasting_Adults_and_Children.pdf
Maltby JR, Sutherland AD, Sale JP, Shaffer EA. Preoperative Oral Fluids: Is a Five-hour Fast Justified Prior to Elective Surgery? Anesth Analg. 1986 Sep;65(11):1112–6. Available from: Https://journals.lww.com/3767008.pmid
Hutchinson A, Maltby JR, Reid CRG. Gastric fluid volume and pH in elective inpatients. Part I: coffee or orange juice versus overnight fast. Can J Anaesth. 1988 Jan;35(1):12–5. Https://doi.org/10.1007/BF03010537
Goresky G V., Maltby JR. Fasting guidelines for elective surgical patients. Can J Anaesth 1990 375. 1990 Jul;37(5):493– 5. Https://doi.org/10.1007/BF03006313
Guidelines for the Minimal Standards of Practice of Anaesthesia. The Canadian Anaesthesists’ Society; 1977.
Guidelines to the Practice of Anaesthesia. The Canadian Anaesthesists’ Society; 1987.
Fasting S, SØReide E, Raeder JC. Changing preoperative fasting policies: Impact of a national consensus. Acta Anaesthesiol Scand. 1998 Nov;42(10):1188–91. Https://doi.org/10.1111/j.1399-6576.1998.tb05275.x
Raeder JC, Fasting S, Aanderud L, Soreide E. Preoperative faste og aspirasjonrutiner. NAForum - Tidskr Nor Anestesiol Foren. 1994;7:21–2.
López Muñoz AC, Busto Aguirreurreta N, Tomás Braulio J. Guías de ayuno preoperatorio: actualización. Rev Esp Anestesiol Reanim. 2015 Mar;62(3):145–56. Https://doi.org/10.1016/j.redar.2014.09.006
College of Anaesthesiologists Academy of Medicine of Malaysia. Guidelines on preoperative fasting. 2008.
Warner MA, Caplan RA, Epstein BS, Gibbs CP, Keller CE, Leak JA, et al. Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures. Anesthesiology. 1999 Mar 1;90(3):896–905. Https://doi.org/10.1097/00000542-199903000-00034
Soreide E, Eriksson LI, Hirlekar G, Eriksson H, Henneberg SW, Sandin R, et al. Pre-operative fasting guidelines: an update. Acta Anaesthesiol Scand. 2005 Sep;49(8):1041–7. Https://doi.org/10.1111/j.1399-6576.2005.00781.x
Schmidt AR, Buehler P, Seglias L, Stark T, Brotschi B, Renner T, et al. Gastric pH and residual volume after 1 and 2 h fasting time for clear fluids in children †. Br J Anaesth. 2015 Mar 1;114(3):477–82. Https://doi.org/10.1093/bja/aeu399
Crenshaw JT. Preoperative Fasting: Will the Evidence Ever Be Put into Practice? AJN, Am J Nurs. 2011 Oct;111(10):38– 43. Https://doi.org/10.1097/01.NAJ.0000406412.57062.24
Dobson G, Chau A, Denomme J, Fuda G, McDonnell C, McIntyre I, et al. Guidelines to the Practice of Anesthesia: Revised Edition 2023. Can J Anesth Can d’anesthésie. 2023 Jan 23;70(1):16–55. Https://doi.org/10.1007/s12630-022-02368-0
Ljungqvist O, Young-Fadok T, Demartines N. The History of Enhanced Recovery After Surgery and the ERAS Society. J Laparoendosc Adv Surg Tech. 2017 Sep;27(9):860–2. Https://doi.org/10.1089/lap.2017.0350
Wilson RD, Caughey AB, Wood SL, Macones GA, Wrench IJ, Huang J, et al. Guidelines for Antenatal and Preoperative care in Cesarean Delivery: Enhanced Recovery After Surgery Society Recommendations (Part 1). Am J Obstet Gynecol. 2018 Dec;219(6):523.e1-523.e15. Https://doi.org/10.1016/j.ajog.2018.09.015
Engelman DT, Ben Ali W, Williams JB, Perrault LP, Reddy VS, Arora RC, et al. Guidelines for Perioperative Care in Cardiac Surgery. JAMA Surg. 2019 Aug 1;154(8):755. Https://doi.org/10.1001/jamasurg.2019.1153
Wainwright TW. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Acta Orthop. 2020 May 3;91(3):363– 363. Https://doi.org/10.1080/17453674.2020.1724674
Debono B, Wainwright TW, Wang MY, Sigmundsson FG, Yang MMH, Smid-Nanninga H, et al. Consensus statement for perioperative care in lumbar spinal fusion: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Spine J. 2021 May;21(5):729–52. Https://doi.org/10.1016/j.spinee.2021.01.001
Brindle ME, McDiarmid C, Short K, Miller K, MacRobie A, Lam JYK, et al. Consensus Guidelines for Perioperative Care in Neonatal Intestinal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations. World J Surg. 2020 Aug 8;44(8):2482–92. Https://doi.org/10.1007/s00268-020-05530-1
Low DE, Allum W, De Manzoni G, Ferri L, Immanuel A, Kuppusamy M, et al. Guidelines for Perioperative Care in Esophagectomy: Enhanced Recovery After Surgery (ERAS®) Society Recommendations. World J Surg. 2019 Feb 1;43(2):299–330. Https://doi.org/10.1007/s00268-018-4786-4
McGinigle KL, Spangler EL, Pichel AC, Ayyash K, Arya S, Settembrini AM, et al. Perioperative care in open aortic vascular surgery: A consensus statement by the Enhanced Recovery After Surgery (ERAS) Society and Society for Vascular Surgery. J Vasc Surg. 2022 Jun;75(6):1796–820. Https://doi.org/10.1016/j.jvs.2022.01.131
Hübner M, Kusamura S, Villeneuve L, Al-Niaimi A, Alyami M, Balonov K, et al. Guidelines for Perioperative Care in Cytoreductive Surgery (CRS) with or without hyperthermic IntraPEritoneal chemotherapy (HIPEC): Enhanced recovery after surgery (ERAS®) Society Recommendations — Part I: Preoperative and intraoperative management. Eur J Surg Oncol. 2020 Dec;46(12):2292–310. Https://doi.org/10.1016/j.ejso.2020.07.041
Peden CJ, Aggarwal G, Aitken RJ, Anderson ID, Bang Foss N, Cooper Z, et al. Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization. World J Surg. 2021 May 6;45(5):1272–90. Https://doi.org/10.1007/s00268-021-05994-9
Ljungqvist O, Scott M, Fearon KC. Enhanced Recovery After Surgery. JAMA Surg. 2017 Mar 1;152(3):292. Https://doi.org/10.1001/jamasurg.2016.4952
Nygren J, Thorell A, Ljungqvist O. Are there any benefits from minimizing fasting and optimization of nutrition and fluid management for patients undergoing day surgery? Curr Opin Anaesthesiol. 2007 Dec;20(6):540–4. Https://doi.org/10.1097/ACO.0b013e3282f15493
Currie A, Burch J, Jenkins JT, Faiz O, Kennedy RH, Ljungqvist O, et al. The Impact of Enhanced Recovery Protocol Compliance on Elective Colorectal Cancer Resection. Ann Surg. 2015 Jun;261(6):1153–9. Https://doi.org/10.1097/SLA.0000000000001029
Gustafsson UO. Adherence to the Enhanced Recovery After Surgery Protocol and Outcomes After Colorectal Cancer Surgery. Arch Surg. 2011 May 1;146(5):571. Https://doi.org/10.1001/archsurg.2010.309
Gustafsson UO, Oppelstrup H, Thorell A, Nygren J, Ljungqvist O. Adherence to the ERAS protocol is Associated with 5-Year Survival After Colorectal Cancer Surgery: A Retrospective Cohort Study. World J Surg. 2016 Jul 25;40(7):1741– 7. Https://doi.org/10.1007/s00268-016-3460-y
Robinson J. A Treatise on the Inhalation of the Vapour of Ether. London: Webster. 1847;
Snow J. On the Inhalation of the Vapour of Ether in Surgical Operations. London John Churchill. 1847;
Lister J. On anaesthetics. In: Holmes System of Surgery. 3rd ed. London: Longmans Green and Co.; 1883.
Hewitt F. The Administration of Nitrous Oxide and Oxygen for Dental Operations. 2nd ed. London: Claudius Ash, sons & Co; 1905.
Gwathmey JT, Baskerville C. Anaesthesia. New York: Appleton; 1914.
Hunt A. Anesthesia Principles and Practice. New York: GP Putnam’s Sons; 1949.
Lee J, Atkinson R. A Synopsis of Anaesthesia. 5th ed. Oxford: John Wright & Sons Ltd.; 1964.
Strunin L. How long should patients fast before surgery? Time for new guidelines. Br J Anaesth. 1993 Jan;70(1):1–3. Https://doi.org/10.1093/bja/70.1.1
Eriksson LI, Sandin R. Fasting guidelines in different countries. Acta Anaesthesiol Scand. 1996 Sep;40(8P2):971–4. Https://doi.org/10.1111/j.1399-6576.1996.tb05614.x
Rincón-Valenzuela DA, Escobar B. Manual de práctica clínica basado en la evidencia: preparación del paciente para el acto quirúrgico y traslado al quirófano. Rev Colomb Anestesiol. 2015 Jan;43(1):32–50. Https://doi.org/10.1016/j.rca.2014.10.009
Bailey CR, Ahuja M, Bartholomew K, Bew S, Forbes L, Lipp A, et al. Guidelines for day‐case surgery 2019. Anaesthesia. 2019 Jun 8;74(6):778–92. Https://doi.org/10.1111/anae.14639
Joshi GP, Abdelmalak BB, Weigel WA, Harbell MW, Kuo CI, Soriano SG, et al. 2023 American Society of Anesthesiologists Practice Guidelines for Preoperative Fasting: Carbohydrate-containing Clear Liquids with or without Protein, Chewing Gum, and Pediatric Fasting Duration—A Modular Update of the 2017 American Society of Anesthesio. Anesthesiology. 2023 Feb 1;138(2):132–51. Https://doi.org/10.1097/ALN.0000000000004381
de Aguilar-Nascimento JE, Dock-Nascimento DB, Cadavid Sierra J. El Proyecto ACERTO: un protocolo multimodal barato y eficaz para América Latina. Rev Nutr Clínica y Metab. 2020 May;3(1):91–9. Https://doi.org/10.35454/rncm.v3n1.018
Holte K, Kehlet H. Compensatory fluid administration for preoperative dehydration - does it improve outcome? Acta Anaesthesiol Scand. 2002 Oct;46(9):1089–93. Https://doi.org/10.1034/j.1399-6576.2002.460906.x
Pearson TC, Guthrie DL, Simpson J, Chinn S, Barosi G, Ferrant A, et al. Interpretation of measured red cell mass and plasma volume in adults: Expert Panel on Radionuclides of the International Council for Standardization in Haematology. Br J Haematol. 1995 Mar 12;89(4):748–56. Https://doi.org/10.1111/j.1365-2141.1995.tb08411.x
Schol PBB, Terink IM, Lancé MD, Scheepers HCJ. Liberal or restrictive fluid management during elective surgery: a systematic review and meta-analysis. J Clin Anesth. 2016;35:26–39. Https://doi.org/10.1016/j.jclinane.2016.07.010
Miller TE, Myles PS. Perioperative Fluid Therapy for Major Surgery. Anesthesiology. 2019 May 1;130(5):825–32. Https://doi.org/10.1097/ALN.0000000000002603
McCue C, Puxty K. Perioperative fluid therapy for anaesthetists and intensivists. Anaesth Intensive Care Med. 2021;22(10):611–4. Https://doi.org/10.1016/j.mpaic.2021.07.009
Aguilar-Nascimento JE de, Bicudo-Salomão A, Caporossi C, Silva R de M, Cardoso EA, Santos TP. Acerto pós- operatório: avaliação dos resultados da implantação de um protocolo multidisciplinar de cuidados peri-operatórios em cirurgia geral. Rev Col Bras Cir. 2006 Jun;33(3):181–8. Https://doi.org/10.1590/S0100-69912006000300010
Engelhardt T, Wilson G, Horne L, Weiss M, Schmitz A. Are you hungry? Are you thirsty? - fasting times in elective outpatient pediatric patients. Pediatr Anesth. 2011 Sep;21(9):964–8. Https://doi.org/10.1111/j.1460-9592.2011.03573.x
The shortened fluid fast and the Canadian Anaesthetists’ Society’s new guidelines for fasting in elective/ emergency patients. Can J Anaesth. 1990 Nov;37(8):905–6. Https://doi.org/10.1007/BF03006632
Sharma S, Deo AS, Raman P. Effectiveness of standard fasting guidelines as assessed by gastric ultrasound examination: A clinical audit. Indian J Anaesth. 2018 Oct 1;62(10):747. Https://doi.org/10.4103/IJA.IJA_54_18
Vaughan RW, Bauer S, Wise L. Volume and pH of Gastric Juice in Obese Patients. Anesthesiology. 1975 Dec 1;43(6):686–8. Https://doi.org/10.1097/00000542-197512000-00021
Sabry R, Hasanin A, Refaat S, Abdel Raouf S, Abdallah AS, Helmy N. Evaluation of gastric residual volume in fasting diabetic patients using gastric ultrasound. Acta Anaesthesiol Scand. 2019 May 4;63(5):615–9. Https://doi.org/10.1111/aas.13315
Ohashi Y, Walker JC, Zhang F, Prindiville FE, Hanrahan JP, Mendelson R, et al. Preoperative Gastric Residual Volumes in Fasted Patients Measured by Bedside Ultrasound: A Prospective Observational Study. Anaesth Intensive Care. 2018 Nov 1;46(6):608–13. Https://doi.org/10.1177/0310057X1804600612
Mohammad Khalil A, Gaber Ragab S, Makram Botros J, Ali Abd-aal H, Labib Boules M. Gastric Residual Volume Assessment by Gastric Ultrasound in Fasting Obese Patients: A Comparative Study. Anesthesiol Pain Med. 2021 Feb 3;11(1):109732. Https://doi.org/10.5812/aapm.109732
Zahorska-Markiewicz B, Jonderko K, Lelek A, Skrzypek D. Gastric emptying in obesity. Hum Nutr Clin Nutr. 1986 Jul;40(4):309–13.
Mora MEV, Scarfone A, Valenza V, Calvani M, Greco A V, Gasbarrini G, et al. Ghrelin Does Not Influence Gastric Emptying in Obese Subjects. Obes Res. 2005 Apr;13(4):739–44. Https://doi.org/10.1038/oby.2005.83
Wright RA, Krinsky S, Fleeman C, Trujillo J, Teague E. Gastric Emptying and Obesity. 1983; Https://doi.org/10.1016/0016-5085(83)90141-5
Brady MC, Kinn S, Stuart P, Ness V. Preoperative fasting for adults to prevent perioperative complications. Cochrane Database Syst Rev. 2003 Oct 20;2010(4). Https://doi.org/10.1002/14651858.CD004423
Fearon KCH, Ljungqvist O, Von Meyenfeldt M, Revhaug A, Dejong CHC, Lassen K, et al. Enhanced recovery after surgery: A consensus review of clinical care for patients undergoing colonic resection. Clin Nutr. 2005 Jun;24(3):466– 77. Https://doi.org/10.1016/j.clnu.2005.02.002
Desiderio J, Trastulli S, Cintio A Di, Commissari R, Colasanti A, Scarcella M, et al. Enhanced Recovery After Surgery (ERAS) Protocol for Gastrectomy: A Tailored Program Developed at a Gastric Cancer Unit. J Gastric Surg. 2020 Feb 29;2(1):12–7. Https://doi.org/10.36159/JGS.V2I1.21
Lassen K, Coolsen MME, Slim K, Carli F, de Aguilar-Nascimento JE, Schäfer M, et al. Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Clin Nutr. 2012 Dec 1;31(6):817–30. Https://doi.org/10.1016/J.CLNU.2012.08.011
Cheuvront SN, Kenefick RW. Dehydration: Physiology, Assessment, and Performance Effects. In: Comprehensive Physiology. Wiley; 2014. p. 257–85. Https://doi.org/10.1002/cphy.c130017
Bhave G, Neilson EG. Volume Depletion Versus Dehydration: How Understanding the Difference Can Guide Therapy. Am J Kidney Dis. 2011 Aug;58(2):302–9. Https://doi.org/10.1053/j.ajkd.2011.02.395
Walsh NP, Laing SJ, Oliver SJ, Montague JC, Walters R, Bilzon JLJ. Saliva parameters as potential indices of hydration status during acute dehydration. Med Sci Sports Exerc. 2004;36(9):1535–42. Https://doi.org/10.1249/01.MSS.0000139797.26760.06
Lawlor PG. Delirium and dehydration: some fluid for thought? Support Care Cancer. 2002 Sep 15;10(6):445–54. Https://doi.org/10.1007/s00520-001-0334-z
Sawka MN, Cheuvront SN, Kenefick RW. Hypohydration and Human Performance: Impact of Environment and Physiological Mechanisms. Sport Med. 2015 Nov 9;45(S1):51–60. Https://doi.org/10.1007/s40279-015-0395-7
Moghadamyeghaneh Z, Phelan MJ, Carmichael JC, Mills SD, Pigazzi A, Nguyen NT, et al. Preoperative Dehydration Increases Risk of Postoperative Acute Renal Failure in Colon and Rectal Surgery. J Gastrointest Surg. 2014 Dec 20;18(12):2178–85. Https://doi.org/10.1007/s11605-014-2661-7
Lacey J, Corbett J, Forni L, Hooper L, Hughes F, Minto G, et al. A multidisciplinary consensus on dehydration: definitions, diagnostic methods and clinical implications. Ann Med. 2019 May 19;51(3–4):232–51. Https://doi.org/10.1080/07853890.2019.1628352
Silva de Assis MC, Moraes Silveira CR de, Gomes Beghetto M, Mello ED de, Aula G, España M, et al. Is duration of postoperative fasting associated with infection and prolonged length of stay in surgical patients? Nutr Hosp. 2014;30:919–26. Https://doi.org/10.3305/nh.2014.30.4.7528
Stachenfeld NS, DiPietro L, Nadel ER, Mack GW. Mechanism of attenuated thirst in aging: role of central volume receptors. Am J Physiol Integr Comp Physiol. 1997 Jan 1;272(1):R148–57. Https://doi.org/10.1152/ajpregu.1997.272.1.R148
Fortes MB, Owen JA, Raymond-Barker P, Bishop C, Elghenzai S, Oliver SJ, et al. Is this elderly patient dehydrated? Diagnostic accuracy of hydration assessment using physical signs, Urine, and saliva markers. J Am Med Dir Assoc. 2015;16(3):221–8. Https://doi.org/10.1016/j.jamda.2014.09.012
Chappell D, Jacob M. Role of the glycocalyx in fluid management: Small things matter. Best Pract Res Clin Anaesthesiol. 2014;28(3):227–34. Https://doi.org/10.1016/j.bpa.2014.06.003
Starling EH. On the Absorption of Fluids from the Connective Tissue Spaces. J Physiol. 1896 May 5;19(4):312–26. Https://doi.org/10.1113/jphysiol.1896.sp000596
Molitoris BA, George AG, Murray PT, Meier D, Reilly ES, Barreto E, et al. A Novel Fluorescent Clinical Method to Rapidly Quantify Plasma Volume. Cardiorenal Med. 2019;9(3):168–79. Https://doi.org/10.1159/000496480
Costill DL, Saltin B. Changes in the ratio of venous to body hematocrit following dehydration. J Appl Physiol. 1974 May 1;36(5):608–10. Https://doi.org/10.1152/jappl.1974.36.5.608
Harrison MH, Graveney MJ, Cochrane LA. Some sources of error in the calculation of relative change in plasma volume. Eur J Appl Physiol Occup Physiol. 1982;50(1):13–21. Https://doi.org/10.1007/BF00952240
Albert SN, Gravel Y, Turmel Y, Albert CA. Pittalls in Blood Volume Measurement. Anesth Analg. 1965 Nov;44(6):805???814. Https://doi.org/10.1213/00000539-196511000-00023
Isbister JP. The F-Cell Ratio: A Clinically Important Parameter or Just Fine Tuning? Transfus Med Hemotherapy. 1995;22(2):69–70. Https://doi.org/10.1159/000223101
Fåhræus R, Lindqvist T. The Viscosity of the Blood in Narrow Capillary Tubes. Am J Physiol Content. 1931 Mar 1;96(3):562–8. Https://doi.org/10.1152/ajplegacy.1931.96.3.562
Svensen CH, Stankevičius E, Broms J, Markevičius V, Andrijauskas A. Evaluation of hydration status calculated from differences in venous and capillary plasma dilution during stepwise crystalloid infusions: A randomized crossover study in healthy volunteers. Medicina (B Aires). 2014;50(5):255–62. Https://doi.org/10.1016/j.medici.2014.09.007
Knowlton RG, Brown DD, Hetzler RK, Sikora LM. Venous and fingertip blood to calculate plasma volume shift following exercise. Med Sci Sport Exerc. 1990 Dec;22(6):854. Https://doi.org/10.1249/00005768-199012000-00019
Yang ZW, Yang SH, Chen L, Qu J, Zhu J, Tang Z. Comparison of blood counts in venous, fingertip and arterial blood and their measurement variation. Clin Lab Haematol. 2001 Jun 11;23(3):155–9. Https://doi.org/10.1046/j.1365-2257.2001.00388.x
Thompson WO, Thompson PK, Dailey ME. The Effect of Posture upon the Composition and Volume of the Blood in Man. Proc Natl Acad Sci. 1928 Jan;14(1):94–8. Https://doi.org/10.1073/pnas.14.1.94
Haller M, Brechtelsbauer H, Akbulut C, Fett W, Briegel J, Finsterer U. Isovolemic Hemodilution Alters the Ratio of Whole-Body to Large-Vessel Hematocrit (F-Cell Ratio). Transfus Med Hemotherapy. 1995;22(2):74–80. Https://doi.org/10.1159/000223103
Hooper L, Abdelhamid A, Attreed NJ, Campbell WW, Channell AM, Chassagne P, et al. Clinical symptoms, signs and tests for identification of impending and current water-loss dehydration in older people. Cochrane Database Syst Rev. 2015 Apr 30;23(4):1–10. Https://doi.org/10.1002/14651858.CD009647.pub2
Muñoz CX, Johnson EC, DeMartini JK, Huggins RA, McKenzie AL, Casa DJ, et al. Assessment of hydration biomarkers including salivary osmolality during passive and active dehydration. Eur J Clin Nutr. 2013 Dec 16;67(12):1257–63. Https://doi.org/10.1038/ejcn.2013.195
Henriksen JH, Jensen GB, Larsson HBW. A century of indicator dilution technique. Clin Physiol Funct Imaging. 2014 Jan;34(1):1–9. Https://doi.org/10.1111/cpf.12068
Ertl AC, Diedrich A, Raj SR. Techniques Used for the Determination of Blood Volume. Am J Med Sci. 2007 Jul;334(1):32–6. Https://doi.org/10.1097/MAJ.0b013e318063c6d1
Dawson AB, Evans HM, Whipple GH. Blood Volume Studies III. Behavior of Large Series of Dyes Introduced into the Circulating Blood. Am J Physiol Content. 1920 Mar 1;51(2):232–56. Https://doi.org/10.1152/ajplegacy.1920.51.2.232
Woodcock JP. Theory and Practice of Blood Flow Measurement [Internet]. Theory and Practice of Blood Flow Measurement. Elsevier; 1975. Https://doi.org/10.1016/C2013-0-06257-3
Armstrong LE. Hydration Assessment Techniques. Nutr Rev. 2005 Jun 1;63(6):40–54. Https://doi.org/10.1301/nr.2005.jun.S40-S54
Barley OR, Chapman DW, Abbiss CR. Reviewing the current methods of assessing hydration in athletes. J Int Soc Sports Nutr. 2020 Jan 3;17(1):1–13. Https://doi.org/10.1186/s12970-020-00381-6
Robarts WM, Parkin J V, Hobsley M. A simple clinical approach to quantifying losses from the extracellular and plasma compartments. Ann R Coll Surg Engl. 1979 Mar;61(2):142–5
Dasselaar JJ, van der Sande FM, Franssen CFM. Critical Evaluation of Blood Volume Measurements during Hemodialysis. Blood Purif. 2012;33(1–3):177–82. Https://doi.org/10.1159/000334142
Cheuvront SN, Ely BR, Kenefick RW, Buller MJ, Charkoudian N, Sawka MN. Hydration assessment using the cardiovascular response to standing. Eur J Appl Physiol. 2012 Dec 6;112(12):4081–9. Https://doi.org/10.1007/s00421-012-2390-0
Loeppky JA, Luther DK, Maes D, Riboni K, Hinghofer-Szalkay H, Charlton GA, et al. Plasma volume by Evans blue: Effects of eating and comparison with other methods at altitude. Aviat Sp Environ Med. 2002;73(9):902–6
Siebenmann C, Robach P, Lundby C. Regulation of blood volume in lowlanders exposed to high altitude. J Appl Physiol. 2017 Oct 1;123(4):957–66. Https://doi.org/10.1152/japplphysiol.00118.2017
Pugh LGCE. Blood volume and haemoglobin concentration at altitudes above 18,000 ft. (5500 m). J Physiol. 1964 Mar 1;170(2):344–54. Https://doi.org/10.1113/jphysiol.1964.sp0073
Aguilar-Barojas S. Fórmulas para el cálculo de la muestra en investigaciones de salud. Salud en Tabasco. 2005 Jul 21;11(1–2):333–8. Available from: Https://www.redalyc.org/articulo.oa?id=48711206
Nordin E, Hellström PM, Brunius C, Landberg R. Modest Conformity Between Self-Reporting of Bristol Stool Form and Fecal Consistency Measured by Stool Water Content in Irritable Bowel Syndrome and a FODMAP and Gluten Trial. Am J Gastroenterol. 2022 Oct;117(10):1668–74. Https://doi.org/10.14309/ajg.0000000000001942
Corney RA, Horina A, Sunderland C, James LJ. Effect of hydration status and fluid availability on ad-libitum energy intake of a semi-solid breakfast. Appetite. 2015 Aug;91:399–404. Https://doi.org/10.1016/j.appet.2015.04.075
Armstrong LE, Ganio MS, Klau JF, Johnson EC, Casa DJ, Maresh CM. Novel hydration assessment techniques employing thirst and a water intake challenge in healthy men. Appl Physiol Nutr Metab. 2014 Feb;39(2):138–44. Https://doi.org/10.1139/apnm-2012-0369
Cook RJ, Dickens BM, Fathalla MF. World Medical Association Declaration of Helsinki. JAMA. 2013 Nov 27;310(20):2191. Https://doi.org/10.1001/jama.2013.281053
Stunkel L, Grady C. More than the money: A review of the literature examining healthy volunteer motivations. Contemp Clin Trials. 2011 May;32(3):342–52. Https://doi.org/10.1016/j.cct.2010.12.003
Sawka MN, Young AJ, Francesconi RP, Muza SR, Pandolf KB. Thermoregulatory and blood responses during exercise at graded hypohydration levels. J Appl Physiol. 1985 Nov 1;59(5):1394–401. Https://doi.org/10.1152/jappl.1985.59.5.1394
Watso JC, Farquhar WB. Hydration Status and Cardiovascular Function. Nutrients. 2019 Aug 1;11(8). Https://doi.org/10.3390/NU11081866
Van PY, Riha GM, Cho SD, Underwood SJ, Hamilton GJ, Anderson R, et al. Blood Volume Analysis Can Distinguish True Anemia From Hemodilution in Critically Ill Patients. J Trauma Inj Infect Crit Care. 2011 Mar;70(3):646–51. Https://doi.org/10.1097/TA.0b013e31820d5f48
Zdolsek J, Metander A, Hahn R. Volume kinetic evaluation of fluid turnover after oral intake of tap water, lemonade and saline in volunteers. BMC Sports Sci Med Rehabil. 2016 Dec 28;8(1):22. Https://doi.org/10.1186/s13102-016-0045-x
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dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia
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dc.publisher.faculty.spa.fl_str_mv Facultad de Medicina
dc.publisher.place.spa.fl_str_mv Bogotá, Colombia
dc.publisher.branch.spa.fl_str_mv Universidad Nacional de Colombia - Sede Bogotá
institution Universidad Nacional de Colombia
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spelling Atribución-CompartirIgual 4.0 Internacionalhttp://creativecommons.org/licenses/by-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Diaztagle Fernández, Juan José9b6bcf74590947ac4e7d862ba28343d3Ramírez Pimiento, Juan David85811cd46c658b4a29c9370f163ba85bRamírez-Pimiento, Juan David [https://orcid.org/0000-0003-2259-6338]2024-07-16T23:22:18Z2024-07-16T23:22:18Z2024https://repositorio.unal.edu.co/handle/unal/86498Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramas, tablasAntecedentes: El ayuno prequirúrgico busca reducir el riesgo de aspiración pulmonar durante la anestesia. Sin embargo, a pesar de las guías actuales, el tiempo de ayuno supera frecuentemente las 12 horas antes de un procedimiento electivo. Objetivos: Describir los efectos del ayuno en el estado hídrico, gasto urinario y volúmenes plasmático y sanguíneo; evidenciados por cambios en el peso, hematocrito y volumen urinario. Métodos: Se realizó un estudio prospectivo cuasiexperimental sin grupo control; se llevaron 18 sujetos (10 hombres, 8 mujeres) a un punto de hipohidratación leve por medio de ayuno absoluto de sólidos y líquidos en un periodo máximo de 24 horas; se midió el peso y el gasto urinario de manera seriada y se tomaron muestras sanguíneas al comienzo y al final del periodo de ayuno. Resultados: Se encontró un déficit hídrico de 16 ml/Kg tras 12 horas de ayuno y una pérdida de 1,038 g/Kg/h en adelante. El tiempo medio para llegar a la hipohidratación fue de 15:09 horas (±3,3h); los sujetos presentaron un descenso del gasto urinario a un promedio de 0,6 ml/Kg/h y se calculó una reducción de los volúmenes sanguíneo y plasmático de 2,9% y 4,18% respectivamente. Conclusiones: El ayuno prolongado como aquel que se presenta antes de un procedimiento quirúrgico puede provocar hipohidratación y oliguria. Esto podría afectar la respuesta ante el reto anestésico y quirúrgico; aumentando la susceptibilidad de complicaciones renales, hemodinámicas, entre otras. Se sugiere que las instituciones tomen medidas que eviten tiempos excesivos de ayuno y las complicaciones relacionadas (Texto tomado de la fuente).Background: Preoperative fasting attempts to reduce aspiration risk during anesthesia; despite current recommendations, fasting time frequently exceeds 12 hours before elective procedures. Objectives: To describe the effects of fasting in hydration status, urinary output, plasma and blood volume; through the measuring of weight loss and changes in hematocrit and spontaneous void of the bladder. Methods: A quasi-experimental, uncontrolled, prospective study was conceived; eighteen subjects (10 male, 8 female) were taken to a mild hypohydration (defined as a water deficit equal to 2% of bodyweight) through fasting in a maximum period of 24 hours; subjects were weighted, and their urine output was measured repeatedly throughout the trial. Blood samples were drawn before and after this fasting period. Results: After 12 hours of fasting, subjects had a water deficit of 16 ml/Kg on average, with an ongoing loss of 1,038 g/Kg/h from there on. A mean time to hypohydration of 15:09 hours (±3,3h) was calculated. Moreover, a decline was observed in urinary output, plasma and blood volumes at the time of hypohydration; median urinary output fell to 0,6 ml/Kg/h, meanwhile blood volume and plasma volume decreased by 2,9% and 4,18% respectively. Conclusions: Prolonged fasting akin to that required before surgical procedures can result in hypohydration and oliguria. These may affect the system’s response to surgical stress and anesthesia management; increasing the risk of renal and hemodynamic complications, amongst others. Institutions ought to address long preoperative fasting and related complications.MaestríaMagister en FisiologíaSe realizó un estudio prospectivo cuasiexperimental sin grupo control; se llevaron 18 sujetos (10 hombres, 8 mujeres) a un punto de hipohidratación leve por medio de ayuno absoluto de sólidos y líquidos en un periodo máximo de 24 horas; se midió el peso y el gasto urinario de manera seriada y se tomaron muestras sanguíneas al comienzo y al final del periodo de ayuno.xvii, 95 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Maestría en FisiologíaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::612 - Fisiología humanaHematócritoPeso CorporalVolumen PlasmáticoHematocritBody WeightPlasma VolumeAyunoEstado de hipohidratación del organismoDeshidrataciónPeriodo preoperatorioOliguriaFastingOrganism hypohydration statusDehydrationPreoperative periodOliguriaAyuno e Hipohidratación en un Periodo de 24 horas, Estudio Piloto Cuasiexperimental en Condiciones Naturales en Voluntarios en BogotáFasting And Hypohydration in A Period Of 24 Hours, A Quasi-Experimental Pilot in Natural Conditions in Volunteers In BogotáTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMBogotáColombiaRomit JJA, van de Mortel T. Ritualistic preoperative fasting: Is it still occurring and what can we do about it? Acorn. 2011;24(1):14–20. [Internet 12/2023]; Available from: Https://research-repository.griffith.edu.au/bitstream/10072/54758/3/90088_1.pdfBilehjani E, Fakhari S, Yavari S, Panahi JR, Afhami M, Nagipour B, et al. Adjustment of Preoperative Fasting Guidelines for Adult Patients Undergoing Elective Surgery. Open J Intern Med. 2015;05(04):115–8. Https://doi.org/10.4236/ojim.2015.54016Gómez A. Líquidos y electrolitos en anestesia. Rev Col Anest. 1984;(179).Liska D, Mah E, Brisbois T, Barrios PL, Baker LB, Spriet LL. Narrative Review of Hydration and Selected Health Outcomes in the General Population. Nutrients. 2019 Jan 1;11(1):70. Https://doi.org/10.3390/nu11010070Petri NM, Dropulić N, Kardum G. Effects of Voluntary Fluid Intake Deprivation on Mental and Psychomotor Performance. Croat Med J. 2006;47(6):855. Available from: Https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/17167858/Miller RD, Eriksson LI, Fleisher LA, Wiener-Kronish JP, Cohen NH, Young WL. Miller’s Anesthesia. Elsevier Health Sciences; 2014. 4094 p.Khoyratty S, Din A, Spendlove R, Teehan M, Arhi C, Modi BN, et al. The Impact of Discussing Preoperative Fasting with Patients. J Perioper Pract. 2011 Aug 1;21(8):284–6. Https://doi.org/10.1177/175045891102100805Connolly J, Cunningham AJ. Preoperative fasting and administration of regular medications in adult patients presenting for elective surgery. Has new evidence changed clinical practice? Eur J Anaesthesiol. 2000 Apr;17(4):219– 20. Https://doi.org/10.1046/j.1365-2346.2000.00603.xJacob M, Chappell D. Effects of perioperative fasting on haemodynamics and intravascular volumes. Best Pract Res Clin Anaesthesiol. 2012 Dec;26(4):421–30. Https://doi.org/10.1016/j.bpa.2012.10.002Watso JC, Babcock MC, Robinson AT, Migdal KU, Wenner MM, Stocker SD, et al. Water deprivation does not augment sympathetic or pressor responses to sciatic afferent nerve stimulation in rats or to static exercise in humans. J Appl Physiol. 2019 Jul 1;127(1):235–45. Https://doi.org/10.1152/japplphysiol.00005.2019Danielsson EJD, Lejbman I, Åkeson J. Fluid deficits during prolonged overnight fasting in young healthy adults. Acta Anaesthesiol Scand. 2019 Feb 21;63(2):195–9. Https://doi.org/10.1111/aas.13254Chacon MM, Markin NW. Part of the Great Fluid Debate—Are Fasting Patients Hypovolemic? J Cardiothorac Vasc Anesth. 2019 Sep;33(9):2428–30. Https://doi.org/10.1053/j.jvca.2019.03.032Park KS, Yoo KY. Role of vasopressin in current anesthetic practice. Korean J Anesthesiol. 2017;70(3):245. Https://doi.org/10.4097/kjae.2017.70.3.245Hall JE, Hall ME. Guyton and Hall: Textbook of Medical Physiology. 14th ed. Elsevier. Elsevier; 2021.Koshimizu T aki, Nakamura K, Egashira N, Hiroyama M, Nonoguchi H, Tanoue A. Vasopressin V1a and V1b Receptors: From Molecules to Physiological Systems. Physiol Rev. 2012 Oct;92(4):1813–64. Https://doi.org/10.1152/physrev.00035.2011Rabbitts JA, Charkoudian N. Sympathetic nervous system and volume-regulatory hormones: interactions during dehydration. Physiol News. 2011 Jan 1;(Winter 2010):39–40. Https://doi.org/10.36866/pn.81.39James LJ, Shirreffs SM. Fluid and Electrolyte Balance During 24-Hour Fluid and/or Energy Restriction. Int J Sport Nutr Exerc Metab. 2013 Dec;23(6):545–53. Https://doi.org/10.1123/ijsnem.23.6.545Oliver SJ, Laing SJ, Wilson S, Bilzon JLJ, Walsh N. Endurance Running Performance after 48 h of Restricted Fluid and/or Energy Intake. Med Sci Sport Exerc. 2007 Feb;39(2):316–22. Https://doi.org/10.1249/01.mss.0000241656.22629.57Fawcett WJ, Thomas M. Pre-operative fasting in adults and children: clinical practice and guidelines. Anaesthesia. 2019 Jan;74(1):83–8. Https://doi.org/10.1111/anae.14500American Society of Anesthesiologists. Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures. Anesthesiology. 2017 Mar 1;126(3):376–93. Https://doi.org/10.1097/ALN.0000000000001452Gustafsson UO, Scott MJ, Hubner M, Nygren J, Demartines N, Francis N, et al. Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018. World J Surg. 2019 Mar 13;43(3):659–95. Https://doi.org/10.1007/s00268-018-4844-yBatchelor TJP, Rasburn NJ, Abdelnour-Berchtold E, Brunelli A, Cerfolio RJ, Gonzalez M, et al. Guidelines for enhanced recovery after lung surgery: recommendations of the Enhanced Recovery After Surgery (ERAS®) Society and the European Society of Thoracic Surgeons (ESTS). Eur J Cardio-Thoracic Surg. 2019 Jan 1;55(1):91–115. Https://doi.org/10.1093/ejcts/ezy301Smith I, Kranke P, Murat I, Smith A, OʼSullivan G, Sreide E, et al. Perioperative fasting in adults and children. Eur J Anaesthesiol. 2011 Aug;28(8):556–69. Https://doi.org/10.1097/EJA.0b013e3283495ba1Morrison CE, Ritchie-McLean S, Jha A, Mythen M. Two hours too long: time to review fasting guidelines for clear fluids. Br J Anaesth. 2020 Apr 1;124(4):363–6. Https://doi.org/10.1016/j.bja.2019.11.036Green SM, Leroy PL, Roback MG, Irwin MG, Andolfatto G, Babl FE, et al. An international multidisciplinary consensus statement on fasting before procedural sedation in adults and children. Anaesthesia. 2020 Mar 2;75(3):374–85. Https://doi.org/10.1111/anae.14892Elliott E, Isserman R, Stricker P, Yaddanapudi S, Subramanyam R. Fasting for anaesthesia: Less is more! Indian J Anaesth. 2020 Feb 1;64(2):87. Https://doi.org/10.4103/ija.IJA_936_19Thomas M, Morrison C, Newton R, Schindler E. Consensus statement on clear fluids fasting for elective pediatric general anesthesia. Pediatr Anesth. 2018 May 1;28(5):411–4. Https://doi.org/10.1111/pan.13370Frykholm P, Schindler E, Sümpelmann R, Walker R, Weiss M. Preoperative fasting in children: review of existing guidelines and recent developments. Br J Anaesth. 2018 Mar 1;120(3):469–74. Https://doi.org/10.1016/j.bja.2017.11.080Frykholm P, Disma N, Andersson H, Beck C, Bouvet L, Cercueil E, et al. Pre-operative fasting in children. Eur J Anaesthesiol. 2022 Jan;39(1):4–25. Https://doi.org/10.1097/EJA.0000000000001599Beck CE, Rudolp D, Becke-Jakob K, Schindler E, Etspüler A, Trapp A, et al. Real fasting times and incidence of pulmonary aspiration in children: Results of a German prospective multicenter observational study. Pediatr Anesth. 2019 Oct 1;29(10):1040–5. Https://doi.org/10.1111/PAN.13725Jacob M, Chappell D, Conzen P, Finsterer U, Rehm M. Blood volume is normal after pre‐operative overnight fasting. Acta Anaesthesiol Scand. 2008 Apr 13;52(4):522–9. Https://doi.org/10.1111/j.1399-6576.2008.01587.xAbebe WA, Rukewe A, Bekele NA, Stoffel M, Nicoh M, Zeberga J. Preoperative fasting times in elective surgical patients at a referral Hospital in Botswana. Pan Afr Med J. 2016;23:1–8. Https://doi.org/10.11604/pamj.2016.23.102.8863Zia F, Cosic L, Wong A, Levin A, Lu P, Mitchell C, et al. Effects of a short message service (SMS) by cellular phone to improve compliance with fasting guidelines in patients undergoing elective surgery: a retrospective observational study. BMC Health Serv Res. 2021 Dec 6;21(1):27. Https://doi.org/10.1186/s12913-020-06039-yEl-Sharkawy AM, Daliya P, Lewis-Lloyd C, Adiamah A, Malcolm FL, Boyd-Carson H, et al. Fasting and surgery timing (FaST) audit. Clin Nutr. 2021 Mar;40(3):1405–12. Https://doi.org/10.1016/j.clnu.2020.08.033Al‐Robeye AM, Barnard AN, Bew S. Thirsty work: Exploring children’s experiences of preoperative fasting. Thomas M, editor. Pediatr Anesth. 2020 Jan 19;30(1):43–9. Https://doi.org/10.1111/pan.13759Isserman R, Elliott E, Subramanyam R, Kraus B, Sutherland T, Madu C, et al. Quality improvement project to reduce pediatric clear liquid fasting times prior to anesthesia. Veyckemans F, editor. Pediatr Anesth. 2019 Jul 2;29(7):698– 704. Https://doi.org/10.1111/pan.13661Cestonaro T, Madalozzo Schieferdecker ME, Thieme RD, Neto Cardoso J, Ligocki Campos AC. The reality of the surgical fasting time in the era of the ERAS protocol. Nutr Hosp. 2014 Feb 1;29(2):437–43. Https://doi.org/10.3305/nh.2014.29.2.7025Ramos-Amézquita MH. Relación entre el ayuno preoperatorio prolongado y la sensación de malestar general en cirugía ambulatoria [Internet]. Universidad Nacional de Colombia; 2019. Available from: Https://repositorio.unal.edu.co/handle/unal/69031Rangel-Miranda FL. Ayuno prolongado y riesgo de náuseas y vómito postoperatorio: estudio de cohorte [Internet]. Universidad Autónoma de Bucaramanga; 2018. Available from: Https://repository.unab.edu.co/handle/20.500.12749/1630Crenshaw JT, Winslow EH. Preoperative Fasting: Old Habits Die Hard. Am J Nurs. 2002 May;102(5):36–44. Https://doi.org/10.1097/00000446-200205000-00033Maltby JR. Fasting from midnight – the history behind the dogma. Best Pract Res Clin Anaesthesiol. 2006 Sep;20(3):363–78. Https://doi.org/10.1016/j.bpa.2006.02.001Chappell D, Jacob M, Hofmann-Kiefer K, Conzen P, Rehm M. A Rational Approach to Perioperative Fluid Management. Anesthesiology. 2008 Oct 1;109(4):723–40. Https://doi.org/10.1097/ALN.0b013e3181863117Tsukamoto M, Hitosugi T, Yokoyama T. Influence of Fasting Duration on Body Fluid and Hemodynamics. Anesth Prog. 2017 Dec 1;64(4):226–9. Https://doi.org/10.2344/anpr-65-01-01Muller L, Brière M, Bastide S, Roger C, Zoric L, Seni G, et al. Preoperative fasting does not affect haemodynamic status: a prospective, non-inferiority, echocardiography study. Br J Anaesth. 2014 May;112(5):835–41. Https://doi.org/10.1093/bja/aet478Field RR, Mai T, Hanna S, Harrington B, Calderon MD, Rinehart J. Lack of impact of nil-per-os (NPO) time on goal- directed fluid delivery in first case versus afternoon case starts: A retrospective cohort study. BMC Anesthesiol. 2019 Oct 27;19(1):1–9. Https://doi.org/10.1186/S12871-019-0864-X/FIGURES/3Kiefer N, Rode C, Baehner T, Zenker S, Hoeft A. Fasting before elective surgery does not result in hypovolaemia. Eur J Anaesthesiol. 2018 Jul;35(7):539–40. Https://doi.org/10.1097/EJA.0000000000000811Bundgaard‐Nielsen M, Jørgensen CC, Kehlet H, Secher NH. Normovolemia defined according to cardiac stroke volume in healthy supine humans. Clin Physiol Funct Imaging. 2010 Sep 10;30(5):318–22. Https://doi.org/10.1111/j.1475-097X.2010.00944.xGeelen G, Greenleaf JE, Keil LC. Drinking-induced plasma vasopressin and norepinephrine changes in dehydrated humans. J Clin Endocrinol Metab. 1996 Jun;81(6):2131–5. Https://doi.org/10.1210/jcem.81.6.8964840Rehm M, Haller M, Orth V, Kreimeier U, Jacob M, Dressel H, et al. Changes in Blood Volume and Hematocrit during Acute Preoperative Volume Loading with 5% Albumin or 6% Hetastarch Solutions in Patients before Radical Hysterectomy. Anesthesiology. 2001 Oct 1;95(4):849–56. Https://doi.org/10.1097/00000542-200110000-00011Corney RA, Horina A, Sunderland C, James LJ. Effect of hydration status and fluid availability on ad-libitum energy intake of a semi-solid breakfast. Appetite. 2015;91:399–404. Https://doi.org/10.1016/j.appet.2015.04.075Mosek A, Korczyn AD. Fasting Headache, Weight Loss, and Dehydration. Headache J Head Face Pain. 1999 Mar;39(3):225–7. Https://doi.org/10.1046/j.1526-4610.1999.3903225.xTortora GJ, Derrickson B. Principios de Anatomía y Fisiología. 13th ed. Panamericana; 2011.Gómez Castilla AM. Correlación entre el tiempo de ayuno preoperatorio y el descenso intraoperatorio de la temperatura central en adultos sometidos a cirugía no cardiaca. 2018; Available from: Https://repositorio.unal.edu.co/handle/unal/63466Salvat Editores, editor. Diccionario Terminológico de Ciencias Médicas. 12th ed. España: Salvat; 1984.Valero J, editor. Enciclopedia Salvat de Ciencias Médicas. 1st ed. Barcelona, España: Salvat; 1955.Maughan RJ, Shirreffs SM. Hydration and performance during Ramadan. J Sports Sci. 2012 Jul;30(sup1):S33–41. Https://doi.org/10.1080/02640414.2012.688140Leiper JB, Molla AM, Molla AM. Effects on health of fluid restriction during fasting in Ramadan. Eur J Clin Nutr. 2003 Dec 1;57(S2):S30–8. Https://doi.org/10.1038/sj.ejcn.1601899Welton S, Minty R, O’Driscoll T, Willms H, Poirier D, Madden S, et al. Intermittent fasting and weight loss: Systematic review. Can Fam Physician. 2020 Feb 1;66(2):117. [Internet 05/2022]; Available from: Https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7021351/Hamdan M, Pucket Y. Total Parenteral Nutrition - StatPearls - NCBI Bookshelf [Internet]. StatPearls Publishing. 2022. [Internet 05/2022]; Available from: Https://www.ncbi.nlm.nih.gov/books/NBK559036/Herbert G, Perry R, Andersen HK, Atkinson C, Penfold C, Lewis SJ, et al. Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of hospital stay and postoperative complications. Cochrane Database Syst Rev. 2019 Jul 22;2019(7). Https://doi.org/10.1002/14651858.CD004080.pub4Yang D, He W, Zhang S, Chen H, Zhang C, He Y. Fast-Track Surgery Improves Postoperative Clinical Recovery and Immunity After Elective Surgery for Colorectal Carcinoma: Randomized Controlled Clinical Trial. World J Surg. 2012 Aug 24;36(8):1874–80. Https://doi.org/10.1007/s00268-012-1606-0Sawka MN, Cheuvront SN, Carter R. Human Water Needs. Nutr Rev. 2005 Jun;63:S30–9. Https://doi.org/10.1111/j.1753-4887.2005.tb00152.xArmstrong LE. Assessing Hydration Status: The Elusive Gold Standard. J Am Coll Nutr. 2007 Oct;26(sup5):575S-584S. Https://doi.org/10.1080/07315724.2007.10719661Lizarralde-Palacios E, Gutiérrez-Macías A, Martínez-Ortiz-de-Zárate M. Alteraciones de la termorregulación. Emergencias. 2000;12(3):192–207. Available from: Http://emergencias.portalsemes.org/numeros- anteriores/volumen-12/numero-3/alteraciones-de-la-termorregulacion/Sawka M, Pandolf K. Effects of body water loss on physiological function and exercise performance. In: Lamb DR, Murray R, Gisolfi C V., editors. Fluid Homeostasis During Exercise. Benchmark Press; 1990.Oppliger RA, Bartok C. Hydration Testing of Athletes. Sport Med. 2002;32(15):959–71. Https://doi.org/10.2165/00007256-200232150-00001Johansen LB, Gharib C, Allevard AM, Sigaudo D, Christensen NJ, Drummer C, et al. Haematocrit, plasma volume and noradrenaline in humans during simulated weightlessness for 42 days. Clin Physiol. 1997 Mar;17(2):203–10. Https://doi.org/10.1046/j.1365-2281.1997.02626.xMaw GJ. Human body-fluid distribution: postural, thermal, and exercise stress [Internet]. 1994. [Internet 05/2021]; Available from: Http://ro.uow.edu.au/theses/1086Stachenfeld NS, Gleim GW, Zabetakis PM, Nicholas JA. Fluid balance and renal response following dehydrating exercise in well-trained men and women. Eur J Appl Physiol Occup Physiol. 1996 Mar;72–72(5–6):468–77. Https://doi.org/10.1007/BF00242277Nose H, Mack GW, Shi XR, Nadel ER. Shift in body fluid compartments after dehydration in humans. J Appl Physiol. 1988 Jul 1;65(1):318–24. Https://doi.org/10.1152/jappl.1988.65.1.318Owen JA, Fortes MB, Ur Rahman S, Jibani M, Walsh NP, Oliver SJ. Hydration Marker Diagnostic Accuracy to Identify Mild Intracellular and Extracellular Dehydration. Int J Sport Nutr Exerc Metab. 2019 Nov 1;29(6):604–11. Https://doi.org/10.1123/ijsnem.2019-0022Dill DB, Costill DL. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol. 1974 Aug;37(2):247–8. Https://doi.org/10.1152/jappl.1974.37.2.247Melin B, Jimenez C, Savourey G, Bittel J, Cottet-Emard JM, Pequignot JM, et al. Effects of hydration state on hormonal and renal responses during moderate exercise in the heat. Eur J Appl Physiol. 1997 Sep 1;76(4):320–7. Https://doi.org/10.1007/s004210050255Jimenez C, Melin B, Koulmann N, Allevard AM, Launay JC, Savourey G. Plasma volume changes during and after acute variations of body hydration level in humans. Eur J Appl Physiol Occup Physiol. 1999 May;80(1):1–8. Https://doi.org/10.1007/s004210050550Sawka MN. Physiological consequences of hypohydration. Med Sci Sport Exerc. 1992 Jun;24(6):657???670. Https://doi.org/10.1249/00005768-199206000-00008Rabbitts JA, Strom NA, Sawyer JR, Curry TB, Dietz NM, Roberts SK, et al. Influence of endogenous angiotensin II on control of sympathetic nerve activity in human dehydration. J Physiol. 2009 Nov 15;587(22):5441–9. Https://doi.org/10.1113/jphysiol.2009.176693Hahn R, Andrijauskas A, Drobin D, Svensén C, Ivaškevičius J. A volume loading test for the detection of hypovolemia and dehydration. Medicina (B Aires). 2008 Sep 28;44(12):953. Https://doi.org/10.3390/medicina44120119Hope A, Aanderud L, Aakvaag A. Dehydration and body fluid-regulating hormones during sweating in warm (38°C) fresh- and seawater immersion. J Appl Physiol. 2001 Oct 1;91(4):1529–34. Https://doi.org/10.1152/jappl.2001.91.4.1529Arnaoutis G, Kavouras SA, Stratakis N, Likka M, Mitrakou A, Papamichael C, et al. The effect of hypohydration on endothelial function in young healthy adults. Eur J Nutr. 2017 Apr 10;56(3):1211–7. Https://doi.org/10.1007/s00394-016-1170-8Desborough JP. The stress response to trauma and surgery. Br J Anaesth. 2000 Jul;85(1):109–17. Https://doi.org/10.1093/bja/85.1.109Prete A, Yan Q, Al-Tarrah K, Akturk HK, Prokop LJ, Alahdab F, et al. The cortisol stress response induced by surgery: A systematic review and meta-analysis. Clin Endocrinol (Oxf). 2018 Nov;89(5):554–67. Https://doi.org/10.1111/cen.13820Snow J. On Chloroform and Other Anaesthetics: Their Action and Administration. Br J Anaesth. 1858 May 1;30(5):247–52. Https://doi.org/10.1093/bja/30.5.247Knight PR, Bacon DR. An Unexplained DeathHannah Greener and Chloroform. Anesthesiology. 2002 May 1;96(5):1250–3. Https://doi.org/10.1097/00000542-200205000-00030Sutherland AD, Stock JG, Davies JM. Effects Of Preoperative Fasting On Morbidity And Gastric Contents In Patients Undergoing Day-Stay Surgery. Br J Anaesth. 1986 Aug;58(8):876–8. Https://doi.org/10.1093/bja/58.8.876Ho YH. Contemporary Issues in Colorectal Surgical Practice [Internet]. Croatia: IntechOpen; 2012. [Internet 07/2021]; Available from: Https://books.google.com.co/books?id=e1WRDwAAQBAJBarash PG, Cahalan MK, Cullen BF, Stock MC, Stoelting RK, Ortega R, editors. Clinical Anesthesia. 7th ed. USA: LIPPINCOTT WILLIAMS & WILKINS; 2013.Mendelson CL. The Aspiration of Stomach Contents into the Lungs During Obstetric Anesthesia. Am J Obstet Gynecol. 1946 Aug 1;52(2):191–205. Https://doi.org/10.1016/S0002-9378(16)39829-5Royal College of Nursing. Perioperative fasting in adults and children An RCN guideline for the multidisciplinary team (full version) [Internet]. 2005. [Internet 07/2021]; Available from: Https://media.gosh.nhs.uk/documents/RCN_Perioperative_Fasting_Adults_and_Children.pdfMaltby JR, Sutherland AD, Sale JP, Shaffer EA. Preoperative Oral Fluids: Is a Five-hour Fast Justified Prior to Elective Surgery? Anesth Analg. 1986 Sep;65(11):1112–6. Available from: Https://journals.lww.com/3767008.pmidHutchinson A, Maltby JR, Reid CRG. Gastric fluid volume and pH in elective inpatients. Part I: coffee or orange juice versus overnight fast. Can J Anaesth. 1988 Jan;35(1):12–5. Https://doi.org/10.1007/BF03010537Goresky G V., Maltby JR. Fasting guidelines for elective surgical patients. Can J Anaesth 1990 375. 1990 Jul;37(5):493– 5. Https://doi.org/10.1007/BF03006313Guidelines for the Minimal Standards of Practice of Anaesthesia. The Canadian Anaesthesists’ Society; 1977.Guidelines to the Practice of Anaesthesia. The Canadian Anaesthesists’ Society; 1987.Fasting S, SØReide E, Raeder JC. Changing preoperative fasting policies: Impact of a national consensus. Acta Anaesthesiol Scand. 1998 Nov;42(10):1188–91. Https://doi.org/10.1111/j.1399-6576.1998.tb05275.xRaeder JC, Fasting S, Aanderud L, Soreide E. Preoperative faste og aspirasjonrutiner. NAForum - Tidskr Nor Anestesiol Foren. 1994;7:21–2.López Muñoz AC, Busto Aguirreurreta N, Tomás Braulio J. Guías de ayuno preoperatorio: actualización. Rev Esp Anestesiol Reanim. 2015 Mar;62(3):145–56. Https://doi.org/10.1016/j.redar.2014.09.006College of Anaesthesiologists Academy of Medicine of Malaysia. Guidelines on preoperative fasting. 2008.Warner MA, Caplan RA, Epstein BS, Gibbs CP, Keller CE, Leak JA, et al. Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures. Anesthesiology. 1999 Mar 1;90(3):896–905. Https://doi.org/10.1097/00000542-199903000-00034Soreide E, Eriksson LI, Hirlekar G, Eriksson H, Henneberg SW, Sandin R, et al. Pre-operative fasting guidelines: an update. Acta Anaesthesiol Scand. 2005 Sep;49(8):1041–7. Https://doi.org/10.1111/j.1399-6576.2005.00781.xSchmidt AR, Buehler P, Seglias L, Stark T, Brotschi B, Renner T, et al. Gastric pH and residual volume after 1 and 2 h fasting time for clear fluids in children †. Br J Anaesth. 2015 Mar 1;114(3):477–82. Https://doi.org/10.1093/bja/aeu399Crenshaw JT. Preoperative Fasting: Will the Evidence Ever Be Put into Practice? AJN, Am J Nurs. 2011 Oct;111(10):38– 43. Https://doi.org/10.1097/01.NAJ.0000406412.57062.24Dobson G, Chau A, Denomme J, Fuda G, McDonnell C, McIntyre I, et al. Guidelines to the Practice of Anesthesia: Revised Edition 2023. Can J Anesth Can d’anesthésie. 2023 Jan 23;70(1):16–55. Https://doi.org/10.1007/s12630-022-02368-0Ljungqvist O, Young-Fadok T, Demartines N. The History of Enhanced Recovery After Surgery and the ERAS Society. J Laparoendosc Adv Surg Tech. 2017 Sep;27(9):860–2. Https://doi.org/10.1089/lap.2017.0350Wilson RD, Caughey AB, Wood SL, Macones GA, Wrench IJ, Huang J, et al. Guidelines for Antenatal and Preoperative care in Cesarean Delivery: Enhanced Recovery After Surgery Society Recommendations (Part 1). Am J Obstet Gynecol. 2018 Dec;219(6):523.e1-523.e15. Https://doi.org/10.1016/j.ajog.2018.09.015Engelman DT, Ben Ali W, Williams JB, Perrault LP, Reddy VS, Arora RC, et al. Guidelines for Perioperative Care in Cardiac Surgery. JAMA Surg. 2019 Aug 1;154(8):755. Https://doi.org/10.1001/jamasurg.2019.1153Wainwright TW. Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Acta Orthop. 2020 May 3;91(3):363– 363. Https://doi.org/10.1080/17453674.2020.1724674Debono B, Wainwright TW, Wang MY, Sigmundsson FG, Yang MMH, Smid-Nanninga H, et al. Consensus statement for perioperative care in lumbar spinal fusion: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Spine J. 2021 May;21(5):729–52. Https://doi.org/10.1016/j.spinee.2021.01.001Brindle ME, McDiarmid C, Short K, Miller K, MacRobie A, Lam JYK, et al. Consensus Guidelines for Perioperative Care in Neonatal Intestinal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations. World J Surg. 2020 Aug 8;44(8):2482–92. Https://doi.org/10.1007/s00268-020-05530-1Low DE, Allum W, De Manzoni G, Ferri L, Immanuel A, Kuppusamy M, et al. Guidelines for Perioperative Care in Esophagectomy: Enhanced Recovery After Surgery (ERAS®) Society Recommendations. World J Surg. 2019 Feb 1;43(2):299–330. Https://doi.org/10.1007/s00268-018-4786-4McGinigle KL, Spangler EL, Pichel AC, Ayyash K, Arya S, Settembrini AM, et al. Perioperative care in open aortic vascular surgery: A consensus statement by the Enhanced Recovery After Surgery (ERAS) Society and Society for Vascular Surgery. J Vasc Surg. 2022 Jun;75(6):1796–820. Https://doi.org/10.1016/j.jvs.2022.01.131Hübner M, Kusamura S, Villeneuve L, Al-Niaimi A, Alyami M, Balonov K, et al. Guidelines for Perioperative Care in Cytoreductive Surgery (CRS) with or without hyperthermic IntraPEritoneal chemotherapy (HIPEC): Enhanced recovery after surgery (ERAS®) Society Recommendations — Part I: Preoperative and intraoperative management. Eur J Surg Oncol. 2020 Dec;46(12):2292–310. Https://doi.org/10.1016/j.ejso.2020.07.041Peden CJ, Aggarwal G, Aitken RJ, Anderson ID, Bang Foss N, Cooper Z, et al. Guidelines for Perioperative Care for Emergency Laparotomy Enhanced Recovery After Surgery (ERAS) Society Recommendations: Part 1—Preoperative: Diagnosis, Rapid Assessment and Optimization. World J Surg. 2021 May 6;45(5):1272–90. Https://doi.org/10.1007/s00268-021-05994-9Ljungqvist O, Scott M, Fearon KC. Enhanced Recovery After Surgery. JAMA Surg. 2017 Mar 1;152(3):292. Https://doi.org/10.1001/jamasurg.2016.4952Nygren J, Thorell A, Ljungqvist O. Are there any benefits from minimizing fasting and optimization of nutrition and fluid management for patients undergoing day surgery? Curr Opin Anaesthesiol. 2007 Dec;20(6):540–4. Https://doi.org/10.1097/ACO.0b013e3282f15493Currie A, Burch J, Jenkins JT, Faiz O, Kennedy RH, Ljungqvist O, et al. The Impact of Enhanced Recovery Protocol Compliance on Elective Colorectal Cancer Resection. Ann Surg. 2015 Jun;261(6):1153–9. Https://doi.org/10.1097/SLA.0000000000001029Gustafsson UO. Adherence to the Enhanced Recovery After Surgery Protocol and Outcomes After Colorectal Cancer Surgery. Arch Surg. 2011 May 1;146(5):571. Https://doi.org/10.1001/archsurg.2010.309Gustafsson UO, Oppelstrup H, Thorell A, Nygren J, Ljungqvist O. Adherence to the ERAS protocol is Associated with 5-Year Survival After Colorectal Cancer Surgery: A Retrospective Cohort Study. World J Surg. 2016 Jul 25;40(7):1741– 7. Https://doi.org/10.1007/s00268-016-3460-yRobinson J. A Treatise on the Inhalation of the Vapour of Ether. London: Webster. 1847;Snow J. On the Inhalation of the Vapour of Ether in Surgical Operations. London John Churchill. 1847;Lister J. On anaesthetics. In: Holmes System of Surgery. 3rd ed. London: Longmans Green and Co.; 1883.Hewitt F. The Administration of Nitrous Oxide and Oxygen for Dental Operations. 2nd ed. London: Claudius Ash, sons & Co; 1905.Gwathmey JT, Baskerville C. Anaesthesia. New York: Appleton; 1914.Hunt A. Anesthesia Principles and Practice. New York: GP Putnam’s Sons; 1949.Lee J, Atkinson R. A Synopsis of Anaesthesia. 5th ed. Oxford: John Wright & Sons Ltd.; 1964.Strunin L. How long should patients fast before surgery? Time for new guidelines. Br J Anaesth. 1993 Jan;70(1):1–3. Https://doi.org/10.1093/bja/70.1.1Eriksson LI, Sandin R. Fasting guidelines in different countries. Acta Anaesthesiol Scand. 1996 Sep;40(8P2):971–4. Https://doi.org/10.1111/j.1399-6576.1996.tb05614.xRincón-Valenzuela DA, Escobar B. Manual de práctica clínica basado en la evidencia: preparación del paciente para el acto quirúrgico y traslado al quirófano. Rev Colomb Anestesiol. 2015 Jan;43(1):32–50. Https://doi.org/10.1016/j.rca.2014.10.009Bailey CR, Ahuja M, Bartholomew K, Bew S, Forbes L, Lipp A, et al. Guidelines for day‐case surgery 2019. Anaesthesia. 2019 Jun 8;74(6):778–92. Https://doi.org/10.1111/anae.14639Joshi GP, Abdelmalak BB, Weigel WA, Harbell MW, Kuo CI, Soriano SG, et al. 2023 American Society of Anesthesiologists Practice Guidelines for Preoperative Fasting: Carbohydrate-containing Clear Liquids with or without Protein, Chewing Gum, and Pediatric Fasting Duration—A Modular Update of the 2017 American Society of Anesthesio. Anesthesiology. 2023 Feb 1;138(2):132–51. Https://doi.org/10.1097/ALN.0000000000004381de Aguilar-Nascimento JE, Dock-Nascimento DB, Cadavid Sierra J. El Proyecto ACERTO: un protocolo multimodal barato y eficaz para América Latina. Rev Nutr Clínica y Metab. 2020 May;3(1):91–9. Https://doi.org/10.35454/rncm.v3n1.018Holte K, Kehlet H. Compensatory fluid administration for preoperative dehydration - does it improve outcome? Acta Anaesthesiol Scand. 2002 Oct;46(9):1089–93. Https://doi.org/10.1034/j.1399-6576.2002.460906.xPearson TC, Guthrie DL, Simpson J, Chinn S, Barosi G, Ferrant A, et al. Interpretation of measured red cell mass and plasma volume in adults: Expert Panel on Radionuclides of the International Council for Standardization in Haematology. Br J Haematol. 1995 Mar 12;89(4):748–56. Https://doi.org/10.1111/j.1365-2141.1995.tb08411.xSchol PBB, Terink IM, Lancé MD, Scheepers HCJ. Liberal or restrictive fluid management during elective surgery: a systematic review and meta-analysis. J Clin Anesth. 2016;35:26–39. Https://doi.org/10.1016/j.jclinane.2016.07.010Miller TE, Myles PS. Perioperative Fluid Therapy for Major Surgery. Anesthesiology. 2019 May 1;130(5):825–32. Https://doi.org/10.1097/ALN.0000000000002603McCue C, Puxty K. Perioperative fluid therapy for anaesthetists and intensivists. Anaesth Intensive Care Med. 2021;22(10):611–4. Https://doi.org/10.1016/j.mpaic.2021.07.009Aguilar-Nascimento JE de, Bicudo-Salomão A, Caporossi C, Silva R de M, Cardoso EA, Santos TP. Acerto pós- operatório: avaliação dos resultados da implantação de um protocolo multidisciplinar de cuidados peri-operatórios em cirurgia geral. Rev Col Bras Cir. 2006 Jun;33(3):181–8. Https://doi.org/10.1590/S0100-69912006000300010Engelhardt T, Wilson G, Horne L, Weiss M, Schmitz A. Are you hungry? Are you thirsty? - fasting times in elective outpatient pediatric patients. Pediatr Anesth. 2011 Sep;21(9):964–8. Https://doi.org/10.1111/j.1460-9592.2011.03573.xThe shortened fluid fast and the Canadian Anaesthetists’ Society’s new guidelines for fasting in elective/ emergency patients. Can J Anaesth. 1990 Nov;37(8):905–6. Https://doi.org/10.1007/BF03006632Sharma S, Deo AS, Raman P. Effectiveness of standard fasting guidelines as assessed by gastric ultrasound examination: A clinical audit. Indian J Anaesth. 2018 Oct 1;62(10):747. Https://doi.org/10.4103/IJA.IJA_54_18Vaughan RW, Bauer S, Wise L. Volume and pH of Gastric Juice in Obese Patients. Anesthesiology. 1975 Dec 1;43(6):686–8. Https://doi.org/10.1097/00000542-197512000-00021Sabry R, Hasanin A, Refaat S, Abdel Raouf S, Abdallah AS, Helmy N. Evaluation of gastric residual volume in fasting diabetic patients using gastric ultrasound. Acta Anaesthesiol Scand. 2019 May 4;63(5):615–9. Https://doi.org/10.1111/aas.13315Ohashi Y, Walker JC, Zhang F, Prindiville FE, Hanrahan JP, Mendelson R, et al. Preoperative Gastric Residual Volumes in Fasted Patients Measured by Bedside Ultrasound: A Prospective Observational Study. Anaesth Intensive Care. 2018 Nov 1;46(6):608–13. Https://doi.org/10.1177/0310057X1804600612Mohammad Khalil A, Gaber Ragab S, Makram Botros J, Ali Abd-aal H, Labib Boules M. Gastric Residual Volume Assessment by Gastric Ultrasound in Fasting Obese Patients: A Comparative Study. Anesthesiol Pain Med. 2021 Feb 3;11(1):109732. Https://doi.org/10.5812/aapm.109732Zahorska-Markiewicz B, Jonderko K, Lelek A, Skrzypek D. Gastric emptying in obesity. Hum Nutr Clin Nutr. 1986 Jul;40(4):309–13.Mora MEV, Scarfone A, Valenza V, Calvani M, Greco A V, Gasbarrini G, et al. Ghrelin Does Not Influence Gastric Emptying in Obese Subjects. Obes Res. 2005 Apr;13(4):739–44. Https://doi.org/10.1038/oby.2005.83Wright RA, Krinsky S, Fleeman C, Trujillo J, Teague E. Gastric Emptying and Obesity. 1983; Https://doi.org/10.1016/0016-5085(83)90141-5Brady MC, Kinn S, Stuart P, Ness V. Preoperative fasting for adults to prevent perioperative complications. Cochrane Database Syst Rev. 2003 Oct 20;2010(4). Https://doi.org/10.1002/14651858.CD004423Fearon KCH, Ljungqvist O, Von Meyenfeldt M, Revhaug A, Dejong CHC, Lassen K, et al. Enhanced recovery after surgery: A consensus review of clinical care for patients undergoing colonic resection. Clin Nutr. 2005 Jun;24(3):466– 77. Https://doi.org/10.1016/j.clnu.2005.02.002Desiderio J, Trastulli S, Cintio A Di, Commissari R, Colasanti A, Scarcella M, et al. Enhanced Recovery After Surgery (ERAS) Protocol for Gastrectomy: A Tailored Program Developed at a Gastric Cancer Unit. J Gastric Surg. 2020 Feb 29;2(1):12–7. Https://doi.org/10.36159/JGS.V2I1.21Lassen K, Coolsen MME, Slim K, Carli F, de Aguilar-Nascimento JE, Schäfer M, et al. Guidelines for perioperative care for pancreaticoduodenectomy: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Clin Nutr. 2012 Dec 1;31(6):817–30. Https://doi.org/10.1016/J.CLNU.2012.08.011Cheuvront SN, Kenefick RW. Dehydration: Physiology, Assessment, and Performance Effects. In: Comprehensive Physiology. Wiley; 2014. p. 257–85. Https://doi.org/10.1002/cphy.c130017Bhave G, Neilson EG. Volume Depletion Versus Dehydration: How Understanding the Difference Can Guide Therapy. Am J Kidney Dis. 2011 Aug;58(2):302–9. Https://doi.org/10.1053/j.ajkd.2011.02.395Walsh NP, Laing SJ, Oliver SJ, Montague JC, Walters R, Bilzon JLJ. Saliva parameters as potential indices of hydration status during acute dehydration. Med Sci Sports Exerc. 2004;36(9):1535–42. Https://doi.org/10.1249/01.MSS.0000139797.26760.06Lawlor PG. Delirium and dehydration: some fluid for thought? Support Care Cancer. 2002 Sep 15;10(6):445–54. Https://doi.org/10.1007/s00520-001-0334-zSawka MN, Cheuvront SN, Kenefick RW. Hypohydration and Human Performance: Impact of Environment and Physiological Mechanisms. Sport Med. 2015 Nov 9;45(S1):51–60. Https://doi.org/10.1007/s40279-015-0395-7Moghadamyeghaneh Z, Phelan MJ, Carmichael JC, Mills SD, Pigazzi A, Nguyen NT, et al. Preoperative Dehydration Increases Risk of Postoperative Acute Renal Failure in Colon and Rectal Surgery. J Gastrointest Surg. 2014 Dec 20;18(12):2178–85. Https://doi.org/10.1007/s11605-014-2661-7Lacey J, Corbett J, Forni L, Hooper L, Hughes F, Minto G, et al. A multidisciplinary consensus on dehydration: definitions, diagnostic methods and clinical implications. Ann Med. 2019 May 19;51(3–4):232–51. Https://doi.org/10.1080/07853890.2019.1628352Silva de Assis MC, Moraes Silveira CR de, Gomes Beghetto M, Mello ED de, Aula G, España M, et al. Is duration of postoperative fasting associated with infection and prolonged length of stay in surgical patients? Nutr Hosp. 2014;30:919–26. Https://doi.org/10.3305/nh.2014.30.4.7528Stachenfeld NS, DiPietro L, Nadel ER, Mack GW. Mechanism of attenuated thirst in aging: role of central volume receptors. Am J Physiol Integr Comp Physiol. 1997 Jan 1;272(1):R148–57. Https://doi.org/10.1152/ajpregu.1997.272.1.R148Fortes MB, Owen JA, Raymond-Barker P, Bishop C, Elghenzai S, Oliver SJ, et al. Is this elderly patient dehydrated? Diagnostic accuracy of hydration assessment using physical signs, Urine, and saliva markers. J Am Med Dir Assoc. 2015;16(3):221–8. Https://doi.org/10.1016/j.jamda.2014.09.012Chappell D, Jacob M. Role of the glycocalyx in fluid management: Small things matter. Best Pract Res Clin Anaesthesiol. 2014;28(3):227–34. Https://doi.org/10.1016/j.bpa.2014.06.003Starling EH. On the Absorption of Fluids from the Connective Tissue Spaces. J Physiol. 1896 May 5;19(4):312–26. Https://doi.org/10.1113/jphysiol.1896.sp000596Molitoris BA, George AG, Murray PT, Meier D, Reilly ES, Barreto E, et al. A Novel Fluorescent Clinical Method to Rapidly Quantify Plasma Volume. Cardiorenal Med. 2019;9(3):168–79. Https://doi.org/10.1159/000496480Costill DL, Saltin B. Changes in the ratio of venous to body hematocrit following dehydration. J Appl Physiol. 1974 May 1;36(5):608–10. Https://doi.org/10.1152/jappl.1974.36.5.608Harrison MH, Graveney MJ, Cochrane LA. Some sources of error in the calculation of relative change in plasma volume. Eur J Appl Physiol Occup Physiol. 1982;50(1):13–21. Https://doi.org/10.1007/BF00952240Albert SN, Gravel Y, Turmel Y, Albert CA. Pittalls in Blood Volume Measurement. Anesth Analg. 1965 Nov;44(6):805???814. Https://doi.org/10.1213/00000539-196511000-00023Isbister JP. The F-Cell Ratio: A Clinically Important Parameter or Just Fine Tuning? Transfus Med Hemotherapy. 1995;22(2):69–70. Https://doi.org/10.1159/000223101Fåhræus R, Lindqvist T. The Viscosity of the Blood in Narrow Capillary Tubes. Am J Physiol Content. 1931 Mar 1;96(3):562–8. Https://doi.org/10.1152/ajplegacy.1931.96.3.562Svensen CH, Stankevičius E, Broms J, Markevičius V, Andrijauskas A. Evaluation of hydration status calculated from differences in venous and capillary plasma dilution during stepwise crystalloid infusions: A randomized crossover study in healthy volunteers. Medicina (B Aires). 2014;50(5):255–62. Https://doi.org/10.1016/j.medici.2014.09.007Knowlton RG, Brown DD, Hetzler RK, Sikora LM. Venous and fingertip blood to calculate plasma volume shift following exercise. Med Sci Sport Exerc. 1990 Dec;22(6):854. Https://doi.org/10.1249/00005768-199012000-00019Yang ZW, Yang SH, Chen L, Qu J, Zhu J, Tang Z. Comparison of blood counts in venous, fingertip and arterial blood and their measurement variation. Clin Lab Haematol. 2001 Jun 11;23(3):155–9. Https://doi.org/10.1046/j.1365-2257.2001.00388.xThompson WO, Thompson PK, Dailey ME. The Effect of Posture upon the Composition and Volume of the Blood in Man. Proc Natl Acad Sci. 1928 Jan;14(1):94–8. Https://doi.org/10.1073/pnas.14.1.94Haller M, Brechtelsbauer H, Akbulut C, Fett W, Briegel J, Finsterer U. Isovolemic Hemodilution Alters the Ratio of Whole-Body to Large-Vessel Hematocrit (F-Cell Ratio). Transfus Med Hemotherapy. 1995;22(2):74–80. Https://doi.org/10.1159/000223103Hooper L, Abdelhamid A, Attreed NJ, Campbell WW, Channell AM, Chassagne P, et al. Clinical symptoms, signs and tests for identification of impending and current water-loss dehydration in older people. Cochrane Database Syst Rev. 2015 Apr 30;23(4):1–10. Https://doi.org/10.1002/14651858.CD009647.pub2Muñoz CX, Johnson EC, DeMartini JK, Huggins RA, McKenzie AL, Casa DJ, et al. Assessment of hydration biomarkers including salivary osmolality during passive and active dehydration. Eur J Clin Nutr. 2013 Dec 16;67(12):1257–63. Https://doi.org/10.1038/ejcn.2013.195Henriksen JH, Jensen GB, Larsson HBW. A century of indicator dilution technique. Clin Physiol Funct Imaging. 2014 Jan;34(1):1–9. Https://doi.org/10.1111/cpf.12068Ertl AC, Diedrich A, Raj SR. Techniques Used for the Determination of Blood Volume. Am J Med Sci. 2007 Jul;334(1):32–6. Https://doi.org/10.1097/MAJ.0b013e318063c6d1Dawson AB, Evans HM, Whipple GH. Blood Volume Studies III. Behavior of Large Series of Dyes Introduced into the Circulating Blood. Am J Physiol Content. 1920 Mar 1;51(2):232–56. Https://doi.org/10.1152/ajplegacy.1920.51.2.232Woodcock JP. Theory and Practice of Blood Flow Measurement [Internet]. Theory and Practice of Blood Flow Measurement. Elsevier; 1975. Https://doi.org/10.1016/C2013-0-06257-3Armstrong LE. Hydration Assessment Techniques. Nutr Rev. 2005 Jun 1;63(6):40–54. Https://doi.org/10.1301/nr.2005.jun.S40-S54Barley OR, Chapman DW, Abbiss CR. Reviewing the current methods of assessing hydration in athletes. J Int Soc Sports Nutr. 2020 Jan 3;17(1):1–13. Https://doi.org/10.1186/s12970-020-00381-6Robarts WM, Parkin J V, Hobsley M. A simple clinical approach to quantifying losses from the extracellular and plasma compartments. Ann R Coll Surg Engl. 1979 Mar;61(2):142–5Dasselaar JJ, van der Sande FM, Franssen CFM. Critical Evaluation of Blood Volume Measurements during Hemodialysis. Blood Purif. 2012;33(1–3):177–82. Https://doi.org/10.1159/000334142Cheuvront SN, Ely BR, Kenefick RW, Buller MJ, Charkoudian N, Sawka MN. Hydration assessment using the cardiovascular response to standing. Eur J Appl Physiol. 2012 Dec 6;112(12):4081–9. Https://doi.org/10.1007/s00421-012-2390-0Loeppky JA, Luther DK, Maes D, Riboni K, Hinghofer-Szalkay H, Charlton GA, et al. Plasma volume by Evans blue: Effects of eating and comparison with other methods at altitude. Aviat Sp Environ Med. 2002;73(9):902–6Siebenmann C, Robach P, Lundby C. Regulation of blood volume in lowlanders exposed to high altitude. J Appl Physiol. 2017 Oct 1;123(4):957–66. Https://doi.org/10.1152/japplphysiol.00118.2017Pugh LGCE. Blood volume and haemoglobin concentration at altitudes above 18,000 ft. (5500 m). J Physiol. 1964 Mar 1;170(2):344–54. Https://doi.org/10.1113/jphysiol.1964.sp0073Aguilar-Barojas S. Fórmulas para el cálculo de la muestra en investigaciones de salud. Salud en Tabasco. 2005 Jul 21;11(1–2):333–8. Available from: Https://www.redalyc.org/articulo.oa?id=48711206Nordin E, Hellström PM, Brunius C, Landberg R. Modest Conformity Between Self-Reporting of Bristol Stool Form and Fecal Consistency Measured by Stool Water Content in Irritable Bowel Syndrome and a FODMAP and Gluten Trial. Am J Gastroenterol. 2022 Oct;117(10):1668–74. Https://doi.org/10.14309/ajg.0000000000001942Corney RA, Horina A, Sunderland C, James LJ. Effect of hydration status and fluid availability on ad-libitum energy intake of a semi-solid breakfast. Appetite. 2015 Aug;91:399–404. Https://doi.org/10.1016/j.appet.2015.04.075Armstrong LE, Ganio MS, Klau JF, Johnson EC, Casa DJ, Maresh CM. Novel hydration assessment techniques employing thirst and a water intake challenge in healthy men. Appl Physiol Nutr Metab. 2014 Feb;39(2):138–44. Https://doi.org/10.1139/apnm-2012-0369Cook RJ, Dickens BM, Fathalla MF. World Medical Association Declaration of Helsinki. JAMA. 2013 Nov 27;310(20):2191. Https://doi.org/10.1001/jama.2013.281053Stunkel L, Grady C. More than the money: A review of the literature examining healthy volunteer motivations. Contemp Clin Trials. 2011 May;32(3):342–52. Https://doi.org/10.1016/j.cct.2010.12.003Sawka MN, Young AJ, Francesconi RP, Muza SR, Pandolf KB. Thermoregulatory and blood responses during exercise at graded hypohydration levels. J Appl Physiol. 1985 Nov 1;59(5):1394–401. Https://doi.org/10.1152/jappl.1985.59.5.1394Watso JC, Farquhar WB. Hydration Status and Cardiovascular Function. Nutrients. 2019 Aug 1;11(8). Https://doi.org/10.3390/NU11081866Van PY, Riha GM, Cho SD, Underwood SJ, Hamilton GJ, Anderson R, et al. Blood Volume Analysis Can Distinguish True Anemia From Hemodilution in Critically Ill Patients. J Trauma Inj Infect Crit Care. 2011 Mar;70(3):646–51. Https://doi.org/10.1097/TA.0b013e31820d5f48Zdolsek J, Metander A, Hahn R. Volume kinetic evaluation of fluid turnover after oral intake of tap water, lemonade and saline in volunteers. BMC Sports Sci Med Rehabil. 2016 Dec 28;8(1):22. 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