Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method
The implementation of primary quantification methods in the National Metrology Institute of Colombia (INM) will allow the certification of reference materials (CRMs) required by Colombia's industrial and scientific fields. One of these materials is potassium hydrogen phthalate (KHP). Furthermor...
- Autores:
-
Smith Osorio, Jessica Lorena
- Tipo de recurso:
- Fecha de publicación:
- 2023
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/83952
- Palabra clave:
- 540 - Química y ciencias afines::543 - Química analítica
540 - Química y ciencias afines::541 - Química física
Potassium hydrogen phthalate
Coulometric titration
Theoretical titration curve
Exponential W-function
Carbon dioxide
Validation
Uncertainty
Coulometric cell geometry
Convection mode
Titulación coulombimetrica
Incertidumbre
Biftalato de potasio
Curva téorica de titulación
Función exponential W
Dióxido de carbono
Geometría de la celda coulombimétrica
Método de convección
Validación
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
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| dc.title.eng.fl_str_mv |
Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method |
| dc.title.translated.spa.fl_str_mv |
Optimización y validación de la titulación coulombimétrica de biftalato de potasio: Un método potencialmente primario |
| title |
Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method |
| spellingShingle |
Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method 540 - Química y ciencias afines::543 - Química analítica 540 - Química y ciencias afines::541 - Química física Potassium hydrogen phthalate Coulometric titration Theoretical titration curve Exponential W-function Carbon dioxide Validation Uncertainty Coulometric cell geometry Convection mode Titulación coulombimetrica Incertidumbre Biftalato de potasio Curva téorica de titulación Función exponential W Dióxido de carbono Geometría de la celda coulombimétrica Método de convección Validación |
| title_short |
Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method |
| title_full |
Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method |
| title_fullStr |
Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method |
| title_full_unstemmed |
Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method |
| title_sort |
Optimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary method |
| dc.creator.fl_str_mv |
Smith Osorio, Jessica Lorena |
| dc.contributor.advisor.none.fl_str_mv |
Ágreda Bastidas, Jesús Alberto Torres Quezada, Henry |
| dc.contributor.author.none.fl_str_mv |
Smith Osorio, Jessica Lorena |
| dc.contributor.educationalvalidator.none.fl_str_mv |
Andrea del Pilar Sandoval Rojas |
| dc.contributor.researchgroup.spa.fl_str_mv |
Grupo de Estudios para la Remediación y Mitigación de Impactos Negativos al Ambiente Germina |
| dc.contributor.orcid.spa.fl_str_mv |
0000-0001-7124-5935 |
| dc.contributor.cvlac.spa.fl_str_mv |
https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001770778 Smith Jessica [0001770778] |
| dc.contributor.researchgate.spa.fl_str_mv |
Smith Jessica [Jessica-Smith-138] |
| dc.subject.ddc.spa.fl_str_mv |
540 - Química y ciencias afines::543 - Química analítica 540 - Química y ciencias afines::541 - Química física |
| topic |
540 - Química y ciencias afines::543 - Química analítica 540 - Química y ciencias afines::541 - Química física Potassium hydrogen phthalate Coulometric titration Theoretical titration curve Exponential W-function Carbon dioxide Validation Uncertainty Coulometric cell geometry Convection mode Titulación coulombimetrica Incertidumbre Biftalato de potasio Curva téorica de titulación Función exponential W Dióxido de carbono Geometría de la celda coulombimétrica Método de convección Validación |
| dc.subject.proposal.eng.fl_str_mv |
Potassium hydrogen phthalate Coulometric titration Theoretical titration curve Exponential W-function Carbon dioxide Validation Uncertainty Coulometric cell geometry Convection mode Titulación coulombimetrica Incertidumbre |
| dc.subject.proposal.spa.fl_str_mv |
Biftalato de potasio Curva téorica de titulación Función exponential W Dióxido de carbono Geometría de la celda coulombimétrica Método de convección |
| dc.subject.proposal.jpn.fl_str_mv |
Validación |
| description |
The implementation of primary quantification methods in the National Metrology Institute of Colombia (INM) will allow the certification of reference materials (CRMs) required by Colombia's industrial and scientific fields. One of these materials is potassium hydrogen phthalate (KHP). Furthermore, coulometry is a well-known potentially primary method because it directly relates the amount of substance to the international system of units (SI). Therefore, we implemented a coulometric system for KHP quantification. Also, a nonlinear regression to the experimental data was made with two models, an exponential W-function (eWf) and our proposal, the theoretical titration curve (TC). One of the main advantages of the TC is the possibility to study and correct the effect of CO2 as the main impurity in the coulometric system. Additionally, the TC allows us to directly estimate the KHP concentration without estimating the endpoint time. On the other hand, using a coulometer developed in this work (CC), we have found that the TC has a better relative uncertainty (0.102 %) compared to the eWf (0.247 %). We also studied the coulometric cell geometry, vertical and horizontal, with two convection modes, ultrasound and magnetic stirring. We obtained no statistical difference between the cell geometry in the amount of substance, and the best convection mode is still magnetic stirring. Finally, using the coulometer developed in INM of Colombia (CC) and the TC, we decreased the uncertainty and bias of the amount of substance of KHP obtained by coulometric titration with respect to the results obtained in the INM of Colombia in the intercomparison study between national metrology institutes in 2016. |
| publishDate |
2023 |
| dc.date.accessioned.none.fl_str_mv |
2023-06-01T20:38:15Z |
| dc.date.available.none.fl_str_mv |
2023-06-01T20:38:15Z |
| dc.date.issued.none.fl_str_mv |
2023-01-10 |
| dc.type.spa.fl_str_mv |
Trabajo de grado - Maestría |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/masterThesis |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
| dc.type.content.spa.fl_str_mv |
Text |
| dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/TM |
| status_str |
acceptedVersion |
| dc.identifier.uri.none.fl_str_mv |
https://repositorio.unal.edu.co/handle/unal/83952 |
| dc.identifier.instname.spa.fl_str_mv |
Universidad Nacional de Colombia |
| dc.identifier.reponame.spa.fl_str_mv |
Repositorio Institucional Universidad Nacional de Colombia |
| dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.unal.edu.co/ |
| url |
https://repositorio.unal.edu.co/handle/unal/83952 https://repositorio.unal.edu.co/ |
| identifier_str_mv |
Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.references.spa.fl_str_mv |
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Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Ágreda Bastidas, Jesús Albertof10aa87ab74187beed42678b5b978ba6Torres Quezada, Henry3bd619086eb9cb9a9a9ef31ae5de0653Smith Osorio, Jessica Lorenad21d2404fc75ccf5fa23dbc3e756b4a0Andrea del Pilar Sandoval RojasGrupo de Estudios para la Remediación y Mitigación de Impactos Negativos al Ambiente Germina0000-0001-7124-5935https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001770778Smith Jessica [0001770778]Smith Jessica [Jessica-Smith-138]2023-06-01T20:38:15Z2023-06-01T20:38:15Z2023-01-10https://repositorio.unal.edu.co/handle/unal/83952Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/The implementation of primary quantification methods in the National Metrology Institute of Colombia (INM) will allow the certification of reference materials (CRMs) required by Colombia's industrial and scientific fields. One of these materials is potassium hydrogen phthalate (KHP). Furthermore, coulometry is a well-known potentially primary method because it directly relates the amount of substance to the international system of units (SI). Therefore, we implemented a coulometric system for KHP quantification. Also, a nonlinear regression to the experimental data was made with two models, an exponential W-function (eWf) and our proposal, the theoretical titration curve (TC). One of the main advantages of the TC is the possibility to study and correct the effect of CO2 as the main impurity in the coulometric system. Additionally, the TC allows us to directly estimate the KHP concentration without estimating the endpoint time. On the other hand, using a coulometer developed in this work (CC), we have found that the TC has a better relative uncertainty (0.102 %) compared to the eWf (0.247 %). We also studied the coulometric cell geometry, vertical and horizontal, with two convection modes, ultrasound and magnetic stirring. We obtained no statistical difference between the cell geometry in the amount of substance, and the best convection mode is still magnetic stirring. Finally, using the coulometer developed in INM of Colombia (CC) and the TC, we decreased the uncertainty and bias of the amount of substance of KHP obtained by coulometric titration with respect to the results obtained in the INM of Colombia in the intercomparison study between national metrology institutes in 2016.La implementación de métodos primarios de medición en el Instituto Nacional de Metrología de Colombia (INM) permitirá la certificación de materiales de referencia (MRCs) los cuales son requeridos en el sector industrial y científico del país. Uno de los MRCs más importantes es el biftalato de potasio (KHP). Por su parte, la coulombimetría es un método altamente conocido por ser potencialmente primario, ya que permite la cuantificación de la cantidad de sustancia en magnitudes del sistema internacional de medidas (SI). En este trabajo, se implementó la titulación coulombimétrica de KHP a nivel metrológico. La implementación incluyó el ajuste de dos modelos a los datos experimentales mediante regresión no lineal: la función exponencial W (eWf) que se ha usado hace varios años, y nuestra nueva propuesta la curva teórica de titulación (TC). Con la TC se pudo estudiar el efecto del CO₂ sobre los resultados de la titulación. El CO₂ es la principal impureza en la titulación coulombimétrica de KHP, y su efecto en el resultado final se corrigió mediante la estimación directa de la concentración de KHP, cosa que se logra con la TC pero que es imposible hacer con la eWf. Por otro lado, y de acuerdo a los parámetros de validación del método desarrollado, se encontró que las incertidumbres relativas obtenidas con TC (0.102 % ) fueron mejores que las obtenidas con eWf (0.247 %). También se estudió la geometría de la celda coulombimétrica, celdas horizontal y vertical, junto con dos métodos de convección, ultrasonido y la agitación magnética. Los resultados indican que no hay diferencia significativa entre la celda vertical y la horizontal. Además, el mejor método de convección resultó ser la agitación magnética. Finalmente, se adecuó un coulombímetro, el cual junto con el uso de la TC, nos permitió disminuir el porcentaje de incertidumbre y sesgo de la cantidad de sustancia de KHP obtenida por titulación coulombimétrica respecto a lo obtenido en el Instituto Nacional de Metrología de Colombia en el estudio de intercomparación de Institutos Nacionales de Metrología de 2.016. (Texto tomado de la fuente)MaestríaMagíster en Ciencias - QuímicaProyecto 9932100271370 ”Plan de fortalecimiento del instituto nacional de metrología como centro de investigación”Química analíticaxxi, 90 páginasapplication/pdfengUniversidad Nacional de ColombiaBogotá - Ciencias - Maestría en Ciencias - QuímicaFacultad de CienciasBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá540 - Química y ciencias afines::543 - Química analítica540 - Química y ciencias afines::541 - Química físicaPotassium hydrogen phthalateCoulometric titrationTheoretical titration curveExponential W-functionCarbon dioxideValidationUncertaintyCoulometric cell geometryConvection modeTitulación coulombimetricaIncertidumbreBiftalato de potasioCurva téorica de titulaciónFunción exponential WDióxido de carbonoGeometría de la celda coulombimétricaMétodo de convecciónValidaciónOptimization and validation of potassium hydrogen phthalate coulometric titration: A potentially primary methodOptimización y validación de la titulación coulombimétrica de biftalato de potasio: Un método potencialmente primarioTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMBIPM et al. 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Elsevier, 1998, pp. 171–230. doi: https://doi.org/10.1016/S0922- 3487(97)80038-X. url: https://www.sciencedirect.com/science/article/pii/ S092234879780038X.Plan de fortalecimiento del instituto nacional de metrología como centro de investigaciónMinCienciasEstudiantesInvestigadoresPúblico generalLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/83952/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINALTesis maestria repositorio 31 mayo.pdfTesis maestria repositorio 31 mayo.pdfTesis de Maestría en Ciencias - Químicaapplication/pdf10792464https://repositorio.unal.edu.co/bitstream/unal/83952/4/Tesis%20maestria%20repositorio%2031%20mayo.pdfae74832f65c9484e20de89220bb8b52dMD54Anexos.zipAnexos.zipAnexosapplication/zip9698484https://repositorio.unal.edu.co/bitstream/unal/83952/3/Anexos.zip1da1768533f0bd07ac8c6254e7a9e789MD53THUMBNAILTesis maestria repositorio 31 mayo.pdf.jpgTesis maestria repositorio 31 mayo.pdf.jpgGenerated 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