Oxidative stress and pesticide disease: a challenge for toxicology
Introduction: In the past decades, the synthesis of chemical compounds has resulted in a high number of substances used to protect crops from pests. Most pesticides have been used in large quantities for agricultural purposes. Acute and chronic poisoning are common among agricultural workers and the...
- Autores:
-
Cortés-Iza, Sandra Catalina
Rodríguez, Alba Isabel
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/64957
- Acceso en línea:
- https://repositorio.unal.edu.co/handle/unal/64957
http://bdigital.unal.edu.co/65980/
- Palabra clave:
- 61 Ciencias médicas; Medicina / Medicine and health
Estrés oxidativo
Pesticidas
Peroxidación de lípido
Toxicidad
Oxidative Stress
Pesticides
Lipid Peroxidation
Toxicity
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
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Oxidative stress and pesticide disease: a challenge for toxicology |
| title |
Oxidative stress and pesticide disease: a challenge for toxicology |
| spellingShingle |
Oxidative stress and pesticide disease: a challenge for toxicology 61 Ciencias médicas; Medicina / Medicine and health Estrés oxidativo Pesticidas Peroxidación de lípido Toxicidad Oxidative Stress Pesticides Lipid Peroxidation Toxicity |
| title_short |
Oxidative stress and pesticide disease: a challenge for toxicology |
| title_full |
Oxidative stress and pesticide disease: a challenge for toxicology |
| title_fullStr |
Oxidative stress and pesticide disease: a challenge for toxicology |
| title_full_unstemmed |
Oxidative stress and pesticide disease: a challenge for toxicology |
| title_sort |
Oxidative stress and pesticide disease: a challenge for toxicology |
| dc.creator.fl_str_mv |
Cortés-Iza, Sandra Catalina Rodríguez, Alba Isabel |
| dc.contributor.author.spa.fl_str_mv |
Cortés-Iza, Sandra Catalina Rodríguez, Alba Isabel |
| dc.subject.ddc.spa.fl_str_mv |
61 Ciencias médicas; Medicina / Medicine and health |
| topic |
61 Ciencias médicas; Medicina / Medicine and health Estrés oxidativo Pesticidas Peroxidación de lípido Toxicidad Oxidative Stress Pesticides Lipid Peroxidation Toxicity |
| dc.subject.proposal.spa.fl_str_mv |
Estrés oxidativo Pesticidas Peroxidación de lípido Toxicidad Oxidative Stress Pesticides Lipid Peroxidation Toxicity |
| description |
Introduction: In the past decades, the synthesis of chemical compounds has resulted in a high number of substances used to protect crops from pests. Most pesticides have been used in large quantities for agricultural purposes. Acute and chronic poisoning are common among agricultural workers and the general population because of their use in different fields. Toxic exposure to these compounds is a major problem for toxicology, as it has an impact on public health due to its significant morbidity and disability. These compounds, when in contact with the human body, produce neurotoxic alterations and trigger molecular mechanisms related to lipid peroxidation, where reactive oxygen species can increase intracellular oxidative processes.Objective: To carry out a review of the scientific literature related to diseases caused by oxidative stress induced by pesticides.Materials and methods: A review of articles in PubMed was carried out using the keywords: Oxidative stress; Pesticides; Lipid peroxidation; Toxicity. The articles related to oxidative stress induced by pesticides were selected.Results: Some hematological, neurological, metabolic and genotoxic diseases may be related to lipid peroxidation induced by pesticides.Conclusion: This article presents a review of the scientific literature on oxidative stress, lipid peroxidation induced by pesticides and the different related diseases that can affect the general population. |
| publishDate |
2018 |
| dc.date.issued.spa.fl_str_mv |
2018-04-01 |
| dc.date.accessioned.spa.fl_str_mv |
2019-07-02T23:37:07Z |
| dc.date.available.spa.fl_str_mv |
2019-07-02T23:37:07Z |
| dc.type.spa.fl_str_mv |
Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_6501 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Text |
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http://purl.org/redcol/resource_type/ART |
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publishedVersion |
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ISSN: 2357-3848 |
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https://repositorio.unal.edu.co/handle/unal/64957 |
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http://bdigital.unal.edu.co/65980/ |
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ISSN: 2357-3848 |
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https://repositorio.unal.edu.co/handle/unal/64957 http://bdigital.unal.edu.co/65980/ |
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spa |
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spa |
| dc.relation.spa.fl_str_mv |
https://revistas.unal.edu.co/index.php/revfacmed/article/view/60783 |
| dc.relation.ispartof.spa.fl_str_mv |
Universidad Nacional de Colombia Revistas electrónicas UN Revista de la Facultad de Medicina Revista de la Facultad de Medicina |
| dc.relation.references.spa.fl_str_mv |
Cortés-Iza, Sandra Catalina and Rodríguez, Alba Isabel (2018) Oxidative stress and pesticide disease: a challenge for toxicology. Revista de la Facultad de Medicina, 66 (2). pp. 261-267. ISSN 2357-3848 |
| dc.rights.spa.fl_str_mv |
Derechos reservados - Universidad Nacional de Colombia |
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http://purl.org/coar/access_right/c_abf2 |
| dc.rights.license.spa.fl_str_mv |
Atribución-NoComercial 4.0 Internacional |
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http://creativecommons.org/licenses/by-nc/4.0/ |
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info:eu-repo/semantics/openAccess |
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Atribución-NoComercial 4.0 Internacional Derechos reservados - Universidad Nacional de Colombia http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
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Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina |
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Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/bitstream/unal/64957/1/60783-389466-1-PB.pdf https://repositorio.unal.edu.co/bitstream/unal/64957/2/60783-389466-1-PB.pdf.jpg |
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Repositorio Institucional Universidad Nacional de Colombia |
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repositorio_nal@unal.edu.co |
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1814089743192817664 |
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Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Cortés-Iza, Sandra Catalina40c5b725-6706-422d-a626-100986e78ba1300Rodríguez, Alba Isabel2203f894-cc1f-4f5b-afbf-2b4798e88ee23002019-07-02T23:37:07Z2019-07-02T23:37:07Z2018-04-01ISSN: 2357-3848https://repositorio.unal.edu.co/handle/unal/64957http://bdigital.unal.edu.co/65980/Introduction: In the past decades, the synthesis of chemical compounds has resulted in a high number of substances used to protect crops from pests. Most pesticides have been used in large quantities for agricultural purposes. Acute and chronic poisoning are common among agricultural workers and the general population because of their use in different fields. Toxic exposure to these compounds is a major problem for toxicology, as it has an impact on public health due to its significant morbidity and disability. These compounds, when in contact with the human body, produce neurotoxic alterations and trigger molecular mechanisms related to lipid peroxidation, where reactive oxygen species can increase intracellular oxidative processes.Objective: To carry out a review of the scientific literature related to diseases caused by oxidative stress induced by pesticides.Materials and methods: A review of articles in PubMed was carried out using the keywords: Oxidative stress; Pesticides; Lipid peroxidation; Toxicity. The articles related to oxidative stress induced by pesticides were selected.Results: Some hematological, neurological, metabolic and genotoxic diseases may be related to lipid peroxidation induced by pesticides.Conclusion: This article presents a review of the scientific literature on oxidative stress, lipid peroxidation induced by pesticides and the different related diseases that can affect the general population.Introducción. En los últimos decenios, la síntesis de compuestos químicos ha producido un alto número de sustancias utilizadas para proteger los cultivos y las cosechas de las plagas. La mayoría de pesticidas han sido usados en grandes cantidades para fines agrícolas y la exposición tóxica a estos compuestos es un problema de gran envergadura para la toxicología, pues tiene impacto en la salud pública por su importante morbilidad y discapacidad. Así, las intoxicaciones agudas y crónicas pueden ser comunes entre trabajadores agrícolas y población general. Estos compuestos desencadenan mecanismos moleculares relacionados con la peroxidación lipídica, donde las especies reactivas de oxigeno pueden incrementar procesos oxidativos intracelulares.Objetivo. Realizar una revisión de la literatura científica relacionada con enfermedades por estrés oxidativo producido por pesticidas.Materiales y métodos. Revisión de artículos que utilizó las palabras clave Estrés oxidativo; Pesticidas; Peroxidación de lípido; Toxicidad. Se eligieron los artículos relacionados con las enfermedades por estrés oxidativo producido por pesticidas.Resultados. Se encontró que algunas enfermedades hematológicas, neurológicas, metabólicas y genotóxicas pueden estar relacionadas con la peroxidación lipídica que producen los pesticidas.Conclusión. Se presenta una revisión de la literatura científica sobre el estrés oxidativo, la peroxidación lipídica inducida por pesticidas y las diferentes enfermedades que pueden afectar a la población en general.application/pdfspaUniversidad Nacional de Colombia - Sede Bogotá - Facultad de Medicinahttps://revistas.unal.edu.co/index.php/revfacmed/article/view/60783Universidad Nacional de Colombia Revistas electrónicas UN Revista de la Facultad de MedicinaRevista de la Facultad de MedicinaCortés-Iza, Sandra Catalina and Rodríguez, Alba Isabel (2018) Oxidative stress and pesticide disease: a challenge for toxicology. Revista de la Facultad de Medicina, 66 (2). pp. 261-267. ISSN 2357-384861 Ciencias médicas; Medicina / Medicine and healthEstrés oxidativoPesticidasPeroxidación de lípidoToxicidadOxidative StressPesticidesLipid PeroxidationToxicityOxidative stress and pesticide disease: a challenge for toxicologyArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTORIGINAL60783-389466-1-PB.pdfapplication/pdf500907https://repositorio.unal.edu.co/bitstream/unal/64957/1/60783-389466-1-PB.pdf472b40c5659a1179575caf7ae865347fMD51THUMBNAIL60783-389466-1-PB.pdf.jpg60783-389466-1-PB.pdf.jpgGenerated Thumbnailimage/jpeg8915https://repositorio.unal.edu.co/bitstream/unal/64957/2/60783-389466-1-PB.pdf.jpgf30dc29d81e6929e960ced26305af161MD52unal/64957oai:repositorio.unal.edu.co:unal/649572023-04-28 23:05:46.005Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co |