Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental

ilustraciones, diagramas, mapas

Autores:: Garcia Cuellar, Yury Paola

Tipo de recurso:

Fecha de publicación:: 2023

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: spa

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network_acronym_str	UNACIONAL2
network_name_str	Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv	Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental
dc.title.translated.eng.fl_str_mv	Determination of persistent organic pollutants in foods with high fat content as an indicator of environmental contamination
title	Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental
spellingShingle	Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental Plaguicidas Contaminación Pesticides Environmental pollution Pollution QuEChERS Contaminantes orgánicos persistentes Leche Cromatografía de gases Análisis de riesgo QuEChERS Persistent organic pollutants Milk Gas chromatography Risk analysis
title_short	Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental
title_full	Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental
title_fullStr	Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental
title_full_unstemmed	Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental
title_sort	Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental
dc.creator.fl_str_mv	Garcia Cuellar, Yury Paola
dc.contributor.advisor.none.fl_str_mv	Guerrero Dallos, Jairo Arturo
dc.contributor.author.none.fl_str_mv	Garcia Cuellar, Yury Paola
dc.contributor.researchgroup.spa.fl_str_mv	Residualidad y Destino Ambiental de Plaguicidas en Sistemas Agricolas
dc.subject.lemb.spa.fl_str_mv	Plaguicidas Contaminación
topic	Plaguicidas Contaminación Pesticides Environmental pollution Pollution QuEChERS Contaminantes orgánicos persistentes Leche Cromatografía de gases Análisis de riesgo QuEChERS Persistent organic pollutants Milk Gas chromatography Risk analysis
dc.subject.lemb.eng.fl_str_mv	Pesticides Environmental pollution Pollution
dc.subject.proposal.spa.fl_str_mv	QuEChERS Contaminantes orgánicos persistentes Leche Cromatografía de gases Análisis de riesgo
dc.subject.proposal.eng.fl_str_mv	QuEChERS Persistent organic pollutants Milk Gas chromatography Risk analysis
description	ilustraciones, diagramas, mapas
publishDate	2023
dc.date.accessioned.none.fl_str_mv	2023-07-19T14:53:12Z
dc.date.available.none.fl_str_mv	2023-07-19T14:53:12Z
dc.date.issued.none.fl_str_mv	2023
dc.type.spa.fl_str_mv	Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv	Text
dc.type.redcol.spa.fl_str_mv	http://purl.org/redcol/resource_type/TM
status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/84220
dc.identifier.instname.spa.fl_str_mv	Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv	https://repositorio.unal.edu.co/
url	https://repositorio.unal.edu.co/handle/unal/84220 https://repositorio.unal.edu.co/
identifier_str_mv	Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv	spa
language	spa
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spelling	Reconocimiento 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Guerrero Dallos, Jairo Arturoa756ad2dad10a8fa9eeb0587db7ee9d3Garcia Cuellar, Yury Paola9c2e4af992ff97f1af8f9c3a20fff70fResidualidad y Destino Ambiental de Plaguicidas en Sistemas Agricolas2023-07-19T14:53:12Z2023-07-19T14:53:12Z2023https://repositorio.unal.edu.co/handle/unal/84220Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramas, mapasEn el presente estudio se implementaron y validaron metodologías para la determinación simultanea de contaminantes organoclorados (COs) y bifenilos policlorados (PCBs) en leche bovina y leche materna por el método QuEChERS con algunas modificaciones, por cromatografía de gases con detector μECD y por espectrometría de masas con cuadrupolo simple y triple cuadrupolo. La idoneidad de los métodos propuestos se ratificó con dos materiales de referencia certificados (BCR 188 y BCR 450). La aplicabilidad se llevó a cabo en 50 muestras de leche bovina y 56 muestras de leche materna, procedentes de diferentes departamentos de Colombia. A partir de los resultados obtenidos se realizó un análisis de riesgo con un enfoque determinístico y probabilístico para identificar el grado de exposición a los contaminantes orgánicos persistentes (COPs). Los métodos validados demostraron ser altamente selectivos/específicos, lineales, exactos, y sensibles, permitiendo obtener límites de cuantificación menores a los límites máximos de residuos (LMR) establecidos por la Comisión Europea y el Codex Alimentario. Los COPs encontrados en leche bovina y materna no superaron los LMR, sin embargo, en la mayoría de las muestras se evidenció la presencia de DDE, DDT y algunos PCBs. El análisis de riesgo determinístico efectuado en ambas matrices permitió identificar porcentajes de la ingesta diaria admisible (%IDA) inferiores al 50%, indicando que no hay riesgos potenciales para la salud de la población. Sin embargo, al realizar el análisis con un enfoque probabilístico se obtuvo que el DDE representaba una probabilidad de 1% en leche bovina y 5.3% en leche materna de superar el umbral toxicológico seguro para el grupo poblacional más expuesto que es la población infantil. Los hallazgos de este estudio proporcionan información valiosa para la determinación de COPs como una herramienta para el análisis de muestras indicadoras de contaminación ambiental. (Texto tomado de la fuente)In the present study, methodologies were implemented and validated for the simultaneous determination of organochlorine contaminants (COs) and polychlorinated biphenyls (PCBs) in bovine milk and breast milk by the QuEChERS method with some modifications, by gas chromatography with μECD detector and by spectrometry of masses with simple quadrupole and triple quadrupole. The suitability of the proposed methods was confirmed with two certified reference materials (BCR 188 and BCR 450). The applicability was carried out in 50 samples of bovine milk and 56 samples of breast milk, coming from different departments of Colombia. Based on the results obtained, a risk analysis was carried out with a deterministic and probabilistic approach to identify the degree of exposure to persistent organic pollutants (POPs). The validated methods proved to be highly selective/specific, linear, exact (absolute error less than 20% with the reference materials), and sensitive, allowing to obtain limits of quantification lower than the maximum residue limits (MRL) established by the European Commission. and the Alimentary Codex. The POPs found in bovine and breast milk did not exceed the MRLs, however, the presence of DDE, DDT and some PCBs was evidenced in most of the samples. The deterministic risk analysis carried out in both matrices made it possible to identify percentages of the acceptable daily intake (% ADI) (a parameter that was considered as an exposure indicator), lower than 50%, indicating that there are no potential risks for the health of the population. However, when carrying out the analysis with a probabilistic approach, it was obtained that the DDE represented a probability of 1% in bovine milk and 5.3% in breast milk of exceeding the safe toxicological threshold for the most exposed population group, which is the infant population. 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Environmental Pollution, 159(2), 524–531. https://doi.org/10.1016/J.ENVPOL.2010.10.014PlaguicidasContaminaciónPesticidesEnvironmental pollutionPollutionQuEChERSContaminantes orgánicos persistentesLecheCromatografía de gasesAnálisis de riesgoQuEChERSPersistent organic pollutantsMilkGas chromatographyRisk analysisPúblico generalLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/84220/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL1083898609.2023.pdf1083898609.2023.pdfTesis de Maestría en Ciencias - Químicaapplication/pdf3511579https://repositorio.unal.edu.co/bitstream/unal/84220/2/1083898609.2023.pdfae0a6d2650a3bd4d482b39b4f5ad6f78MD52THUMBNAIL1083898609.2023.pdf.jpg1083898609.2023.pdf.jpgGenerated Thumbnailimage/jpeg5203https://repositorio.unal.edu.co/bitstream/unal/84220/3/1083898609.2023.pdf.jpg4cdb1ca80924b738309441fb1bb4f9b7MD53unal/84220oai:repositorio.unal.edu.co:unal/842202023-08-12 23:04:14.208Repositorio 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Determinación de contaminantes orgánicos persistentes en alimentos con alto contenido de grasa como indicador de contaminación ambiental

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