Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia
ilustraciones, tablas
- Autores:
-
Rodríguez Criollo, Jairo Alonso
- Tipo de recurso:
- Fecha de publicación:
- 2022
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/81064
- Palabra clave:
- 610 - Medicina y salud::616 - Enfermedades
Infecciones por Coronavirus
Enfermedades del Sistema Digestivo
Hepatopatías
Coronavirus Infections
Digestive System Diseases
Liver Diseases
COVID-19
SARS-CoV-2
Liver function tests
Perfil hepático
Coronavirus
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
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Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia |
| dc.title.translated.eng.fl_str_mv |
Prevalence of gastrointestinal manifestations in patients with COVID-19: Cross sectional study in Bogotá, Colombia |
| title |
Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia |
| spellingShingle |
Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia 610 - Medicina y salud::616 - Enfermedades Infecciones por Coronavirus Enfermedades del Sistema Digestivo Hepatopatías Coronavirus Infections Digestive System Diseases Liver Diseases COVID-19 SARS-CoV-2 Liver function tests Perfil hepático Coronavirus |
| title_short |
Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia |
| title_full |
Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia |
| title_fullStr |
Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia |
| title_full_unstemmed |
Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia |
| title_sort |
Prevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia |
| dc.creator.fl_str_mv |
Rodríguez Criollo, Jairo Alonso |
| dc.contributor.advisor.spa.fl_str_mv |
Otero Regino, William Alberto Ruíz Morales, Oscar Fernando |
| dc.contributor.author.spa.fl_str_mv |
Rodríguez Criollo, Jairo Alonso |
| dc.subject.ddc.spa.fl_str_mv |
610 - Medicina y salud::616 - Enfermedades |
| topic |
610 - Medicina y salud::616 - Enfermedades Infecciones por Coronavirus Enfermedades del Sistema Digestivo Hepatopatías Coronavirus Infections Digestive System Diseases Liver Diseases COVID-19 SARS-CoV-2 Liver function tests Perfil hepático Coronavirus |
| dc.subject.decs.spa.fl_str_mv |
Infecciones por Coronavirus Enfermedades del Sistema Digestivo Hepatopatías |
| dc.subject.decs.eng.fl_str_mv |
Coronavirus Infections Digestive System Diseases Liver Diseases |
| dc.subject.proposal.eng.fl_str_mv |
COVID-19 SARS-CoV-2 Liver function tests |
| dc.subject.proposal.spa.fl_str_mv |
Perfil hepático Coronavirus |
| description |
ilustraciones, tablas |
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2022 |
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2022-02-25T22:36:17Z |
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2022-02-25T22:36:17Z |
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2022 |
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Trabajo de grado - Especialidad Médica |
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info:eu-repo/semantics/masterThesis |
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Universidad Nacional de Colombia |
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Repositorio Institucional Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/ |
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Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
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spa |
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Organización Mundial de la Salud. COVID-19 : Cronología de la actuación de la OMS. Organización Mundial de la Salud. 2020. p. 1–5. Ding S, Liang TJ. Is SARS-CoV-2 Also an Enteric Pathogen With Potential Fecal–Oral Transmission? A COVID-19 Virological and Clinical Review. Gastroenterology. 2020 Jul;159(1):53–61 Taneja S, Mehtani R, Chawla YK. Gastrointestinal and Liver Manifestations of COVID-19. Annals of the National Academy of Medical Sciences (India). 2020 Apr 30;56(02):091–8. Pascarella G, Strumia A, Piliego C, Bruno F, del Buono R, Costa F, et al. COVID‐19 diagnosis and management: a comprehensive review. Journal of Internal Medicine [Internet]. 2020 Aug 13;288(2):192–206. Available from: https://onlinelibrary.wiley.com/doi/10.1111/joim.13091 Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA - Journal of the American Medical Association. 2020;323(11):1061–9. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical characteristics of coronavirus disease 2019 in China. New England Journal of Medicine. 2020;382(18):1708–20 Guo Y-R, Cao Q-D, Hong Z-S, Tan Y-Y, Chen S-D, Jin H-J, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status. Military Medical Research. 2020 Dec 13;7(1):11. Dong E, Du H, Gardner L. An interactive web-based dashboard to track COVID-19 in real time. The Lancet Infectious Diseases. 2020;20(5):533–4. COVID-19 en Colombia [Internet]. Ins. 2021 [cited 2021 Mar 13]. Available from: https://www.ins.gov.co/Noticias/Paginas/Coronavirus.aspx Lai C, Ko W, Lee P, Jean S, Hsueh P. Extra-respiratory manifestations of COVID-19. International Journal of Antimicrobial Agents. 2020 Aug;56(2):106024 Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003 Nov;426(6965):450–4. Luo S, Zhang X, Xu H. Don’t Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19). Clinical Gastroenterology and Hepatology [Internet]. 2020 Jun 1;18(7):1636–7. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1542356520304018 Fang D, Ma J, Guan J, Wang M, Song Y, Tian D, et al. Manifestations of Digestive system in hospitalized patients with novel coronavirus pneumonia in Wuhan, China: a single-center, descriptive study. Chinese Journal of Digestion. 2020;40(00). Cheung KS, Hung IFN, Chan PPY, Lung KC, Tso E, Liu R, et al. Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples From a Hong Kong Cohort: Systematic Review and Meta-analysis. Gastroenterology. 2020 Jul;159(1):81–95. Lai CC, Ko WC, Lee PI, Jean SS, Hsueh PR. Extra-respiratory manifestations of COVID-19. International Journal of Antimicrobial Agents. 2020 Aug 1;56(2). Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine [Internet]. 2020 Apr 30;382(18):1708–20. Available from: http://www.nejm.org/doi/10.1056/NEJMoa2002032 Weber S, Mayerle J, Irlbeck M, Gerbes AL. Severe liver failure during SARS-CoV-2 infection. Gut. 2020 Jul 18;69(7):1365–7 Gandhi RT, Lynch JB, del Rio C. Mild or Moderate Covid-19. Solomon CG, editor. New England Journal of Medicine. 2020 Oct 29;383(18):1757–66. Lavezzo E, Franchin E, Ciavarella C, Cuomo-Dannenburg G, Barzon L, Vecchio C Del, et al. Suppression of COVID-19 outbreak in the municipality of Vo’, Italy. medRxiv. 2020;1–23 Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. JAMA [Internet]. 2020 Mar 17;323(11):1061. Available from: https://jamanetwork.com/journals/jama/fullarticle/2761044 Zhang J, Dong X, Cao Y, Yuan Y, Yang Y, Yan Y, et al. Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China. Allergy [Internet]. 2020 Jul 27;75(7):1730–41. Available from: https://onlinelibrary.wiley.com/doi/10.1111/all.14238 Mao R, Qiu Y, He J-S, Tan J-Y, Li X-H, Liang J, et al. Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis. The Lancet Gastroenterology & Hepatology [Internet]. 2020 Jul 1;5(7):667–78. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2468125320301266 Luo S, Zhang X, Xu H. Don’t Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19). Clinical Gastroenterology and Hepatology. 2020 Jun;18(7):1636–7. Saavedra Trujillo CH. Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID 19 en establecimientos de atención de la salud. Recomendaciones basadas en consenso de expertos e informadas en la evidencia. Infectio [Internet]. 2020 Mar 26;24(3):1. Available from: http://www.revistainfectio.org/index.php/infectio/article/view/851 Kelly CR, Fischer M, Allegretti JR, LaPlante K, Stewart DB, Limketkai BN, et al. ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections. American Journal of Gastroenterology [Internet]. 2021 Jun 1;116(6):1124–47. Available from: https://journals.lww.com/10.14309/ajg.0000000000001278 Otero Regino W, Gómez Zuleta MA, Angel Arango LA, Ruíz Morales OF, Marulanda Fernández H, Riveros J, et al. Procedimientos endoscópicos y pandemia COVID19. Consideraciones básicas. Revista Colombiana de Gastroenterología [Internet]. 2020 Mar 27;35(1):65–75. Available from: https://revistagastrocol.com/index.php/rcg/article/view/526 Chai X, Hu L, Zhang Y, Han W, Lu Z, Ke A, et al. Specific ACE2 expression in cholangiocytes may cause liver damage after 2019-nCoV infection. bioRxiv. 2020 Sheinenzon A, Shehadeh M, Michelis R, Shaoul E, Ronen O. Serum albumin levels and inflammation. International Journal of Biological Macromolecules [Internet]. 2021 Aug 1;184:857–62. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0141813021013696 Mendizabal M, Piñero F, Ridruejo E, Anders M, Silveyra MD, Torre A, et al. Prospective Latin American cohort evaluating outcomes of patients with COVID-19 and abnormal liver tests on admission. Annals of Hepatology [Internet]. 2021 Mar 1;21:100298. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1665268120302234 Zhang Y, Zheng L, Liu L, Zhao M, Xiao J, Zhao Q. Liver impairment in COVID‐19 patients: A retrospective analysis of 115 cases from a single centre in Wuhan city, China. Liver International [Internet]. 2020 Sep 28;40(9):2095–103. Available from: https://onlinelibrary.wiley.com/doi/10.1111/liv.14455 Cai Q, Huang D, Yu H, Zhu Z, Xia Z, Su Y, et al. COVID-19: Abnormal liver function tests. Journal of Hepatology [Internet]. 2020 Sep 1;73(3):566–74. Available from: https://linkinghub.elsevier.com/retrieve/pii/S016882782030218X |
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28 páginas |
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Bogotá |
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Colombia |
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Universidad Nacional de Colombia |
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Bogotá - Medicina - Especialidad en Gastroenterología |
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Departamento de Medicina Interna |
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Facultad de Medicina |
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Bogotá, Colombia |
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Universidad Nacional de Colombia - Sede Bogotá |
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Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Otero Regino, William Alberto554008ee5d0709d2d4b0ba1218488e20Ruíz Morales, Oscar Fernando55459175041891e42c31e14379458886600Rodríguez Criollo, Jairo Alonso1c82267e3e67cbd107c3e635c50624c02022-02-25T22:36:17Z2022-02-25T22:36:17Z2022https://repositorio.unal.edu.co/handle/unal/81064Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, tablasPrevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, Colombia Introducción: El compromiso gastrointestinal en COVID-19 se presenta en el 20% de los pacientes aproximadamente y puede incluir nauseas, vomito, dolor abdominal, diarrea o alteración del perfil hepático. En nuestro país, no se han estudiado las características del compromiso gastrointestinal en los pacientes con COVID-19. Objetivos: Determinar la prevalencia de compromiso gastrointestinal y hepático en pacientes con COVID-19 atendidos en dos hospitales de Bogotá, Colombia. Determinar la asociación del compromiso gastrointestinal por COVID-19 con estancia hospitalaria, severidad y mortalidad. Metodología: Estudio de corte transversal, realizado en dos hospitales de una subred hospitalaria de Bogotá, Colombia, entre febrero del 2020 y marzo del 2021. Resultados. Se incluyeron 1176 pacientes con RT-PCR respiratoria positiva. Las manifestaciones gastrointestinales se presentaron en el 50% (IC95% 47-52%), las más frecuentes fueron diarrea en el 18,4%, odinofagia 17,6%, anorexia 14.7% y dolor abdominal en el 8,8%. Se demostró asociación de la diarrea durante la hospitalización con hospitalización prolongada (OR 1.93 IC95% 1.19-3.13), sangrado gastrointestinal al ingreso con mortalidad (OR 3.13, IC95% 1.1-9.1), entre otros. Las alteraciones del perfil hepático se presentaron en el 46% (IC95% 43-49%), siendo mayor la alteración en pacientes con enfermedad grave o mortalidad. Conclusiones: La prevalencia de las manifestaciones gastrointestinales en pacientes con COVID-19 fue de 50%. La diarrea se asoció a una mayor estancia hospitalaria, el sangrado gastrointestinal se asoció a falla ventilatoria y mortalidad. Las alteraciones del perfil hepático se observaron en el 46% de los pacientes, siendo la elevación de transaminasas el hallazgo más frecuente. Se demostró que la elevación de la AST desde el ingreso se asocia a mayor mortalidad. (Texto tomado de la fuente).Prevalence of gastrointestinal manifestations in patients with COVID-19: Cross sectional study in Bogotá, Colombia Introduction: Approximately 20% of patients with COVID-19 have gastrointestinal compromise. This can include sickness, vomit, abdominal pain, diarrhea, and abnormalities in the hepatic function tests. In Colombia, there are not studies of the characteristics of the gastrointestinal compromise in patients with COVID-19. Objectives: Establish the prevalence of gastrointestinal and hepatic compromise in patients with COVID-19 treated in two hospitals of Bogotá, Colombia. Establish the association of the gastrointestinal compromise in patients with COVID-19 with long hospital stay, severity of disease and mortality. Materials and methods: Cross sectional study made in two hospitals of one sub-network of Health Service in Bogotá, Colombia, between February 2020 and March 2021. Results: We included 1176 patients with COVID-19 confirmed with respiratory RT-PCR. The gastrointestinal manifestations were present in 50% (CI95% 47-52%), the most prevalent manifestation was diarrhea in the 18,4%, odynophagia in the 17,6%, anorexia 14,7% and abdominal pain in 8,8%. There was association of diarrhea and long hospital stay (OR 1.93 CI95% 1.19-3.13), gastrointestinal bleeding with mortality (OR 3.13, CI95% 1.1-9.1), among others. The hepatic function tests were abnormal in 46% of the patients (CI95% 43-49%), the abnormalities were worst in patients with severe COVID-19 or mortality. Conclusions: The prevalence of gastrointestinal manifestation in patients with COVID-19 was 50%. The diarrhea was associated with long hospital stay and the gastrointestinal bleeding was associated with respiratory failure and mortality. The abnormalities of hepatic function tests were present in the 46% of the patients and thEspecialidades MédicasEspecialista en GastroenterologíaEste es un estudio de corte transversal realizado en la USS Occidente de Kennedy y USS Fontibón, ambos hospitales de la Subred integrada de servicios de salud suroccidente ESE de Bogotá, Colombia, desde febrero 2020 hasta marzo del 2021. Los incluyeron pacientes mayores de 18 años con diagnóstico confirmado de infección por SARS-CoV-2 por RT-PCR respiratoria. Se excluyeron a los pacientes con historia clínica no accesible, incompleta o con incongruencias significativas, remitidos y gestantes. Se clasificó la severidad de COVID-19 como crítico si hubo falla ventilatoria con ventilación mecánica invasiva, choque o disfunción multiorgánica; severo si había saturación de oxígeno < 90%, frecuencia respiratoria > 30 respiraciones por minuto, infiltrados pulmonares > 50% de los campos pulmonares; moderado si había compromiso pulmonar dado por disnea o alteraciones en la radiografía de tórax con saturación de oxígeno > 90% y leve si no había disnea ni hipoxemia y fue manejado en casa(18). Se obtuvo la aprobación del comité de ética e investigación de la subred integrada de servicios de salud suroccidente ESE de Bogotá y del comité de ética de la facultad de medicina de la Universidad Nacional de Colombia.28 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Especialidad en GastroenterologíaDepartamento de Medicina InternaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::616 - EnfermedadesInfecciones por CoronavirusEnfermedades del Sistema DigestivoHepatopatíasCoronavirus InfectionsDigestive System DiseasesLiver DiseasesCOVID-19SARS-CoV-2Liver function testsPerfil hepáticoCoronavirusPrevalencia de manifestaciones gastrointestinales de la COVID-19 en pacientes de una institución hospitalaria de Bogotá, ColombiaPrevalence of gastrointestinal manifestations in patients with COVID-19: Cross sectional study in Bogotá, ColombiaTrabajo de grado - Especialidad Médicainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMBogotáColombiaOrganización Mundial de la Salud. COVID-19 : Cronología de la actuación de la OMS. Organización Mundial de la Salud. 2020. p. 1–5.Ding S, Liang TJ. Is SARS-CoV-2 Also an Enteric Pathogen With Potential Fecal–Oral Transmission? A COVID-19 Virological and Clinical Review. Gastroenterology. 2020 Jul;159(1):53–61Taneja S, Mehtani R, Chawla YK. Gastrointestinal and Liver Manifestations of COVID-19. Annals of the National Academy of Medical Sciences (India). 2020 Apr 30;56(02):091–8.Pascarella G, Strumia A, Piliego C, Bruno F, del Buono R, Costa F, et al. COVID‐19 diagnosis and management: a comprehensive review. Journal of Internal Medicine [Internet]. 2020 Aug 13;288(2):192–206. Available from: https://onlinelibrary.wiley.com/doi/10.1111/joim.13091Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA - Journal of the American Medical Association. 2020;323(11):1061–9.Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical characteristics of coronavirus disease 2019 in China. New England Journal of Medicine. 2020;382(18):1708–20Guo Y-R, Cao Q-D, Hong Z-S, Tan Y-Y, Chen S-D, Jin H-J, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status. Military Medical Research. 2020 Dec 13;7(1):11.Dong E, Du H, Gardner L. An interactive web-based dashboard to track COVID-19 in real time. The Lancet Infectious Diseases. 2020;20(5):533–4.COVID-19 en Colombia [Internet]. Ins. 2021 [cited 2021 Mar 13]. Available from: https://www.ins.gov.co/Noticias/Paginas/Coronavirus.aspxLai C, Ko W, Lee P, Jean S, Hsueh P. Extra-respiratory manifestations of COVID-19. International Journal of Antimicrobial Agents. 2020 Aug;56(2):106024Li W, Moore MJ, Vasilieva N, Sui J, Wong SK, Berne MA, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature. 2003 Nov;426(6965):450–4.Luo S, Zhang X, Xu H. Don’t Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19). Clinical Gastroenterology and Hepatology [Internet]. 2020 Jun 1;18(7):1636–7. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1542356520304018Fang D, Ma J, Guan J, Wang M, Song Y, Tian D, et al. Manifestations of Digestive system in hospitalized patients with novel coronavirus pneumonia in Wuhan, China: a single-center, descriptive study. Chinese Journal of Digestion. 2020;40(00).Cheung KS, Hung IFN, Chan PPY, Lung KC, Tso E, Liu R, et al. Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples From a Hong Kong Cohort: Systematic Review and Meta-analysis. Gastroenterology. 2020 Jul;159(1):81–95.Lai CC, Ko WC, Lee PI, Jean SS, Hsueh PR. Extra-respiratory manifestations of COVID-19. International Journal of Antimicrobial Agents. 2020 Aug 1;56(2).Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine [Internet]. 2020 Apr 30;382(18):1708–20. Available from: http://www.nejm.org/doi/10.1056/NEJMoa2002032Weber S, Mayerle J, Irlbeck M, Gerbes AL. Severe liver failure during SARS-CoV-2 infection. Gut. 2020 Jul 18;69(7):1365–7Gandhi RT, Lynch JB, del Rio C. Mild or Moderate Covid-19. Solomon CG, editor. New England Journal of Medicine. 2020 Oct 29;383(18):1757–66.Lavezzo E, Franchin E, Ciavarella C, Cuomo-Dannenburg G, Barzon L, Vecchio C Del, et al. Suppression of COVID-19 outbreak in the municipality of Vo’, Italy. medRxiv. 2020;1–23Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. JAMA [Internet]. 2020 Mar 17;323(11):1061. Available from: https://jamanetwork.com/journals/jama/fullarticle/2761044Zhang J, Dong X, Cao Y, Yuan Y, Yang Y, Yan Y, et al. Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China. Allergy [Internet]. 2020 Jul 27;75(7):1730–41. Available from: https://onlinelibrary.wiley.com/doi/10.1111/all.14238Mao R, Qiu Y, He J-S, Tan J-Y, Li X-H, Liang J, et al. Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis. The Lancet Gastroenterology & Hepatology [Internet]. 2020 Jul 1;5(7):667–78. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2468125320301266Luo S, Zhang X, Xu H. Don’t Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19). Clinical Gastroenterology and Hepatology. 2020 Jun;18(7):1636–7.Saavedra Trujillo CH. Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID 19 en establecimientos de atención de la salud. Recomendaciones basadas en consenso de expertos e informadas en la evidencia. Infectio [Internet]. 2020 Mar 26;24(3):1. Available from: http://www.revistainfectio.org/index.php/infectio/article/view/851Kelly CR, Fischer M, Allegretti JR, LaPlante K, Stewart DB, Limketkai BN, et al. ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections. American Journal of Gastroenterology [Internet]. 2021 Jun 1;116(6):1124–47. Available from: https://journals.lww.com/10.14309/ajg.0000000000001278Otero Regino W, Gómez Zuleta MA, Angel Arango LA, Ruíz Morales OF, Marulanda Fernández H, Riveros J, et al. Procedimientos endoscópicos y pandemia COVID19. Consideraciones básicas. Revista Colombiana de Gastroenterología [Internet]. 2020 Mar 27;35(1):65–75. Available from: https://revistagastrocol.com/index.php/rcg/article/view/526Chai X, Hu L, Zhang Y, Han W, Lu Z, Ke A, et al. Specific ACE2 expression in cholangiocytes may cause liver damage after 2019-nCoV infection. bioRxiv. 2020Sheinenzon A, Shehadeh M, Michelis R, Shaoul E, Ronen O. Serum albumin levels and inflammation. International Journal of Biological Macromolecules [Internet]. 2021 Aug 1;184:857–62. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0141813021013696Mendizabal M, Piñero F, Ridruejo E, Anders M, Silveyra MD, Torre A, et al. Prospective Latin American cohort evaluating outcomes of patients with COVID-19 and abnormal liver tests on admission. Annals of Hepatology [Internet]. 2021 Mar 1;21:100298. Available from: https://linkinghub.elsevier.com/retrieve/pii/S1665268120302234Zhang Y, Zheng L, Liu L, Zhao M, Xiao J, Zhao Q. Liver impairment in COVID‐19 patients: A retrospective analysis of 115 cases from a single centre in Wuhan city, China. Liver International [Internet]. 2020 Sep 28;40(9):2095–103. Available from: https://onlinelibrary.wiley.com/doi/10.1111/liv.14455Cai Q, Huang D, Yu H, Zhu Z, Xia Z, Su Y, et al. COVID-19: Abnormal liver function tests. Journal of Hepatology [Internet]. 2020 Sep 1;73(3):566–74. Available from: https://linkinghub.elsevier.com/retrieve/pii/S016882782030218XEstudiantesORIGINAL1033712804.2022.pdf1033712804.2022.pdfTesis de Especialidad en Gastroenterologíaapplication/pdf528995https://repositorio.unal.edu.co/bitstream/unal/81064/3/1033712804.2022.pdf631d3a433d028b383d290a1ace61dd21MD53LICENSElicense.txtlicense.txttext/plain; charset=utf-84074https://repositorio.unal.edu.co/bitstream/unal/81064/4/license.txt8153f7789df02f0a4c9e079953658ab2MD54THUMBNAIL1033712804.2022.pdf.jpg1033712804.2022.pdf.jpgGenerated Thumbnailimage/jpeg4916https://repositorio.unal.edu.co/bitstream/unal/81064/5/1033712804.2022.pdf.jpgb82edae5422922c25745e3d1f3572778MD55unal/81064oai:repositorio.unal.edu.co:unal/810642023-08-02 23:03:35.933Repositorio Institucional Universidad Nacional de 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