Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation

This thesis presents a model based on cellular automata and evolutionary computation, the purpose of the model is to abstract the behaviour and properties of a bacterial colony. In the bacterial colony, each bacterium has a set of properties and interacts with the environment and other bacteria. Dep...

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Autores:: Panche Gutierrez, Stifen

Tipo de recurso:

Fecha de publicación:: 2015

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: spa

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spelling	Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Gómez Perdomo, JonatanPanche Gutierrez, Stifen49a0ed1b-1605-45e4-a601-aa720e676ac33002019-06-29T18:30:58Z2019-06-29T18:30:58Z2015-05-15https://repositorio.unal.edu.co/handle/unal/53824http://bdigital.unal.edu.co/48494/This thesis presents a model based on cellular automata and evolutionary computation, the purpose of the model is to abstract the behaviour and properties of a bacterial colony. In the bacterial colony, each bacterium has a set of properties and interacts with the environment and other bacteria. Depending on environment characteristics, a bacterium can carry out a set of actions (to reproduce itself, transfer plasmids, die). The obtained results show that the application of the correct use of antibiotics (the correct type of antibiotics, at the correct generation, with the correct dosis) may cause the extinction of the bacterial colony; on the opposite, the antibiotic resistance is obtained as emergent property in the bacterial colony if the mechanism of action of antibiotics is not appropriate.Resumen. Esta tesis presenta un modelo basado en autómatas celulares y computación evolutiva que permite abstraer el comportamiento de una población bacteriana en un ambiente hóstil. Se define un ecosistema donde convive una población de bacterias y a cada bacteria se le definen un conjunto de propiedades; las bacterias interactúan con el ambiente y con las bacterias que la rodean permitiendo que la colonia bacteriana evolucione. En las bacterias a través de varias generaciones pueden surgir mutaciones, procesos de conjugación y muerte de manera natural o a causa de la acción de antibióticos. Los resultados experimentales muestran que el uso de un antibiótico apropiado, con la dosis apropiada, puede causar la desaparición de la colonia bacteriana; al contrario, si el proceso de suministro de antibióticos no es el apropiado, se genera la resistencia a antibióticos como una propiedad emergente en la colonia bacteriana.Maestríaapplication/pdfspaUniversidad Nacional de Colombia Sede Bogotá Facultad de Ingeniería Departamento de Ingeniería de Sistemas e IndustrialDepartamento de Ingeniería de Sistemas e IndustrialPanche Gutierrez, Stifen (2015) Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation. Maestría thesis, Universidad Nacional de Colombia.0 Generalidades / Computer science, information and general works57 Ciencias de la vida; Biología / Life sciences; biology62 Ingeniería y operaciones afines / EngineeringBacterial ConjugationCellular AutomataMechanism of Action of AntibioticsEvolutionary ComputationMutationPlasmidsAntibiotics ResistanceConjugación BacterianaAutómatas CelularesMecanismo de Acción de AntibióticosComputación EvolutivaMutaciónPlásmidosResistencia a AntibióticosModel of Bacterial Conjugation using a Cellular Automaton and Evolutionary ComputationTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMORIGINAL1032387866.2015.pdfapplication/pdf2111150https://repositorio.unal.edu.co/bitstream/unal/53824/1/1032387866.2015.pdf39ae32c645668c1dcc3e7052bf780f85MD51THUMBNAIL1032387866.2015.pdf.jpg1032387866.2015.pdf.jpgGenerated Thumbnailimage/jpeg4410https://repositorio.unal.edu.co/bitstream/unal/53824/2/1032387866.2015.pdf.jpg86d2aed6089179596edb49bc63913eb7MD52unal/53824oai:repositorio.unal.edu.co:unal/538242024-03-09 23:07:55.899Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co
dc.title.spa.fl_str_mv	Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation
title	Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation
spellingShingle	Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation 0 Generalidades / Computer science, information and general works 57 Ciencias de la vida; Biología / Life sciences; biology 62 Ingeniería y operaciones afines / Engineering Bacterial Conjugation Cellular Automata Mechanism of Action of Antibiotics Evolutionary Computation Mutation Plasmids Antibiotics Resistance Conjugación Bacteriana Autómatas Celulares Mecanismo de Acción de Antibióticos Computación Evolutiva Mutación Plásmidos Resistencia a Antibióticos
title_short	Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation
title_full	Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation
title_fullStr	Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation
title_full_unstemmed	Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation
title_sort	Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation
dc.creator.fl_str_mv	Panche Gutierrez, Stifen
dc.contributor.author.spa.fl_str_mv	Panche Gutierrez, Stifen
dc.contributor.spa.fl_str_mv	Gómez Perdomo, Jonatan
dc.subject.ddc.spa.fl_str_mv	0 Generalidades / Computer science, information and general works 57 Ciencias de la vida; Biología / Life sciences; biology 62 Ingeniería y operaciones afines / Engineering
topic	0 Generalidades / Computer science, information and general works 57 Ciencias de la vida; Biología / Life sciences; biology 62 Ingeniería y operaciones afines / Engineering Bacterial Conjugation Cellular Automata Mechanism of Action of Antibiotics Evolutionary Computation Mutation Plasmids Antibiotics Resistance Conjugación Bacteriana Autómatas Celulares Mecanismo de Acción de Antibióticos Computación Evolutiva Mutación Plásmidos Resistencia a Antibióticos
dc.subject.proposal.spa.fl_str_mv	Bacterial Conjugation Cellular Automata Mechanism of Action of Antibiotics Evolutionary Computation Mutation Plasmids Antibiotics Resistance Conjugación Bacteriana Autómatas Celulares Mecanismo de Acción de Antibióticos Computación Evolutiva Mutación Plásmidos Resistencia a Antibióticos
description	This thesis presents a model based on cellular automata and evolutionary computation, the purpose of the model is to abstract the behaviour and properties of a bacterial colony. In the bacterial colony, each bacterium has a set of properties and interacts with the environment and other bacteria. Depending on environment characteristics, a bacterium can carry out a set of actions (to reproduce itself, transfer plasmids, die). The obtained results show that the application of the correct use of antibiotics (the correct type of antibiotics, at the correct generation, with the correct dosis) may cause the extinction of the bacterial colony; on the opposite, the antibiotic resistance is obtained as emergent property in the bacterial colony if the mechanism of action of antibiotics is not appropriate.
publishDate	2015
dc.date.issued.spa.fl_str_mv	2015-05-15
dc.date.accessioned.spa.fl_str_mv	2019-06-29T18:30:58Z
dc.date.available.spa.fl_str_mv	2019-06-29T18:30:58Z
dc.type.spa.fl_str_mv	Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv	Text
dc.type.redcol.spa.fl_str_mv	http://purl.org/redcol/resource_type/TM
status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/53824
dc.identifier.eprints.spa.fl_str_mv	http://bdigital.unal.edu.co/48494/
url	https://repositorio.unal.edu.co/handle/unal/53824 http://bdigital.unal.edu.co/48494/
dc.language.iso.spa.fl_str_mv	spa
language	spa
dc.relation.ispartof.spa.fl_str_mv	Universidad Nacional de Colombia Sede Bogotá Facultad de Ingeniería Departamento de Ingeniería de Sistemas e Industrial Departamento de Ingeniería de Sistemas e Industrial
dc.relation.references.spa.fl_str_mv	Panche Gutierrez, Stifen (2015) Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation. Maestría thesis, Universidad Nacional de Colombia.
dc.rights.spa.fl_str_mv	Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv	http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv	Atribución-NoComercial 4.0 Internacional
dc.rights.uri.spa.fl_str_mv	http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.accessrights.spa.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	Atribución-NoComercial 4.0 Internacional Derechos reservados - Universidad Nacional de Colombia http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv	openAccess
dc.format.mimetype.spa.fl_str_mv	application/pdf
institution	Universidad Nacional de Colombia
bitstream.url.fl_str_mv	https://repositorio.unal.edu.co/bitstream/unal/53824/1/1032387866.2015.pdf https://repositorio.unal.edu.co/bitstream/unal/53824/2/1032387866.2015.pdf.jpg
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repository.name.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
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Model of Bacterial Conjugation using a Cellular Automaton and Evolutionary Computation

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