High yield fermentation of haemophilus influenzae and protein p6 expression: an approach to the production of a purified vaccine. part i
The present article describes an efficient, simple and unexpensive method for the production of high cellular densities of Haemophilus influenzae for cellular and cell free vaccine production. We present here a liquid culture-based method that had not been successfully implemented in Colombia, so fa...
- Autores:
-
Zuluaga, D.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 1998
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/40848
- Acceso en línea:
- https://repositorio.unal.edu.co/handle/unal/40848
http://bdigital.unal.edu.co/30945/
- Palabra clave:
- Haemophilus influenciae
fermentation
outer membrane antigens
P6 protein
Haemophilus influenzae
Fermentación
Antígenos de membrana externa
proteina P6
- Rights
- closedAccess
- License
- Atribución-NoComercial 4.0 Internacional
| Summary: | The present article describes an efficient, simple and unexpensive method for the production of high cellular densities of Haemophilus influenzae for cellular and cell free vaccine production. We present here a liquid culture-based method that had not been successfully implemented in Colombia, so far having given low yields and high costs. The kinetics, costs and production of the most promisory antigen candidates for vaccine production were evaluated in liquid and solid reference media. |
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