Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño

Objective: A cost-effectiveness analysis was conducted for the control and eradication program of bovine Brucellosis using the vaccine against strain 19 in the Department of Nariño (Colombia). Materials and methods: A cost-effectiveness study was conducted using a deterministic model with a hypothet...

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Autores:
Astaiza Martínez, Juan M.
Benavides-Melo, Janneth C.
Díaz-Rojas, Jorge A.
Tipo de recurso:
Article of journal
Fecha de publicación:
2012
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/49312
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/49312
http://bdigital.unal.edu.co/42769/
http://bdigital.unal.edu.co/42769/2/
Palabra clave:
brucelosis
bovinos
costo-efectividad
eficiencia
Nariño
farmacoeconomía
brucellosis
bovine
cost-effectiveness
efficiency
Nariño
pharmacoeconomics
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
id UNACIONAL2_5d804b0ddd2b205ffcdb71fc34540335
oai_identifier_str oai:repositorio.unal.edu.co:unal/49312
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño
title Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño
spellingShingle Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño
brucelosis
bovinos
costo-efectividad
eficiencia
Nariño
farmacoeconomía
brucellosis
bovine
cost-effectiveness
efficiency
Nariño
pharmacoeconomics
title_short Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño
title_full Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño
title_fullStr Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño
title_full_unstemmed Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño
title_sort Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño
dc.creator.fl_str_mv Astaiza Martínez, Juan M.
Benavides-Melo, Janneth C.
Díaz-Rojas, Jorge A.
dc.contributor.author.spa.fl_str_mv Astaiza Martínez, Juan M.
Benavides-Melo, Janneth C.
Díaz-Rojas, Jorge A.
dc.subject.proposal.spa.fl_str_mv brucelosis
bovinos
costo-efectividad
eficiencia
Nariño
farmacoeconomía
brucellosis
bovine
cost-effectiveness
efficiency
Nariño
pharmacoeconomics
topic brucelosis
bovinos
costo-efectividad
eficiencia
Nariño
farmacoeconomía
brucellosis
bovine
cost-effectiveness
efficiency
Nariño
pharmacoeconomics
description Objective: A cost-effectiveness analysis was conducted for the control and eradication program of bovine Brucellosis using the vaccine against strain 19 in the Department of Nariño (Colombia). Materials and methods: A cost-effectiveness study was conducted using a deterministic model with a hypothetic cohort of 100.000 animals, the time horizon was from the time of vaccination until the animals go into production (24 months). A model of the natural history of disease was constructed with data extracted from literature review, the costs were established from the perspective of SAGAN in 2008, the lowest effectiveness figure for the vaccine was used with a conservative illness scenario, and a sensitivity analysis was performed for the prevalence variables, milk price, and the cost and coverage of the vaccine. Results: A favorable cost-effectiveness relation for the different health outcomes analyzed within this work (Abortions, temporal infertility, mortality, prenatal mortality, milk and meat Production) was found. Conclusions: The Brucellosis control and eradication program in the Department Nariño against strain 19 is efficient from SAGAN's perspective; this program should count with support on the part of relevant institutions for the epidemiologic vigilance of this disease.
publishDate 2012
dc.date.issued.spa.fl_str_mv 2012
dc.date.accessioned.spa.fl_str_mv 2019-06-29T08:34:48Z
dc.date.available.spa.fl_str_mv 2019-06-29T08:34:48Z
dc.type.spa.fl_str_mv Artículo de revista
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
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dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/49312
dc.identifier.eprints.spa.fl_str_mv http://bdigital.unal.edu.co/42769/
http://bdigital.unal.edu.co/42769/2/
url https://repositorio.unal.edu.co/handle/unal/49312
http://bdigital.unal.edu.co/42769/
http://bdigital.unal.edu.co/42769/2/
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.spa.fl_str_mv http://revistas.unal.edu.co/index.php/rccquifa/article/view/45095
dc.relation.ispartof.spa.fl_str_mv Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico Farmacéuticas
Revista Colombiana de Ciencias Químico Farmacéuticas
dc.relation.ispartofseries.none.fl_str_mv Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 2 (2012); 167-186 0034-7418 1909-6356
dc.relation.references.spa.fl_str_mv Astaiza Martínez, Juan M. and Benavides-Melo, Janneth C. and Díaz-Rojas, Jorge A. (2012) Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño. Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 2 (2012); 167-186 0034-7418 1909-6356 .
dc.rights.spa.fl_str_mv Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
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dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
Derechos reservados - Universidad Nacional de Colombia
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Revista Colombiana de Ciencias Químico Farmacéuticas
institution Universidad Nacional de Colombia
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spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Astaiza Martínez, Juan M.a215fc9e-3248-406f-accc-b0dc1d04244e300Benavides-Melo, Janneth C.d6eaf587-0f5d-4295-b24b-24a475bb3656300Díaz-Rojas, Jorge A.8742ac30-3dd0-4e31-9671-7938a04f33a73002019-06-29T08:34:48Z2019-06-29T08:34:48Z2012https://repositorio.unal.edu.co/handle/unal/49312http://bdigital.unal.edu.co/42769/http://bdigital.unal.edu.co/42769/2/Objective: A cost-effectiveness analysis was conducted for the control and eradication program of bovine Brucellosis using the vaccine against strain 19 in the Department of Nariño (Colombia). Materials and methods: A cost-effectiveness study was conducted using a deterministic model with a hypothetic cohort of 100.000 animals, the time horizon was from the time of vaccination until the animals go into production (24 months). A model of the natural history of disease was constructed with data extracted from literature review, the costs were established from the perspective of SAGAN in 2008, the lowest effectiveness figure for the vaccine was used with a conservative illness scenario, and a sensitivity analysis was performed for the prevalence variables, milk price, and the cost and coverage of the vaccine. Results: A favorable cost-effectiveness relation for the different health outcomes analyzed within this work (Abortions, temporal infertility, mortality, prenatal mortality, milk and meat Production) was found. Conclusions: The Brucellosis control and eradication program in the Department Nariño against strain 19 is efficient from SAGAN's perspective; this program should count with support on the part of relevant institutions for the epidemiologic vigilance of this disease.Objetivo. Determinar la eficiencia del programa de vacunación en bovinos contra Brucella abortus en el departamento de Nariño, desde la perspectiva de la Sociedad de Agricultores y Ganaderos de Nariño (Sagán). Materiales y métodos. Se realizó un estudio costo-efectividad empleando un modelo determinístico, el horizonte de tiempo fue desde la vacunación de los animales hasta que inician producción (24 meses). Se construyó un modelo de la historia natural de la enfermedad basado en revisión de literatura; los costos se establecieron desde la perspectiva de Sagán en el año 2008, se utilizó la menor efectividad de la vacuna reportada en la literatura y el escenario más conservador de la enfermedad mediante un análisis de sensibilidad en las principales variables. Resultados. Se encontró que la vacuna cepa 19 en una cohorte hipotética de 100.000 animales y con una prevalencia de la enfermedad de 8,6% permite un ahorro de $1.302.670.935. Al analizar la razón costo-efectividad incremental se observa que en las diferentes variables el programa de vacunación es dominante y se produce una relación costo-efectividad favorable en los diversos resultados en salud analizados.Conclusiones. El programa de control y erradicación de brucelosis en el departamento de Nariño con vacuna cepa 19 es eficiente desde la perspectiva de Sagán.application/pdfspaRevista Colombiana de Ciencias Químico Farmacéuticashttp://revistas.unal.edu.co/index.php/rccquifa/article/view/45095Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico FarmacéuticasRevista Colombiana de Ciencias Químico FarmacéuticasRevista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 2 (2012); 167-186 0034-7418 1909-6356Astaiza Martínez, Juan M. and Benavides-Melo, Janneth C. and Díaz-Rojas, Jorge A. (2012) Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariño. Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 2 (2012); 167-186 0034-7418 1909-6356 .Cost-effectiveness analysis of the vaccination program against bovine brucella abortus in the department of nariñoArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTbrucelosisbovinoscosto-efectividadeficienciaNariñofarmacoeconomíabrucellosisbovinecost-effectivenessefficiencyNariñopharmacoeconomicsORIGINAL45095-216208-1-SM.pdfapplication/pdf329417https://repositorio.unal.edu.co/bitstream/unal/49312/1/45095-216208-1-SM.pdf7496ffb686a171e3c93c74031f505219MD51THUMBNAIL45095-216208-1-SM.pdf.jpg45095-216208-1-SM.pdf.jpgGenerated Thumbnailimage/jpeg6475https://repositorio.unal.edu.co/bitstream/unal/49312/2/45095-216208-1-SM.pdf.jpg39a56001ec713115bd9f68ab28be12dfMD52unal/49312oai:repositorio.unal.edu.co:unal/493122022-12-14 23:03:51.563Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co