La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura

ilustraciones, graficas

Autores:: Hernandez Tilaguy, Lorena Sofia

Tipo de recurso:

Fecha de publicación:: 2022

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: spa

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oai_identifier_str	oai:repositorio.unal.edu.co:unal/81634
network_acronym_str	UNACIONAL2
network_name_str	Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv	La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura
dc.title.translated.eng.fl_str_mv	Saliva as an alternative for the detection of drugs of abuse: a systematic review of the literature
title	La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura
spellingShingle	La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura 610 - Medicina y salud::614 - Medicina Forense; incidencia de lesiones, heridas, enfermedades; medicina preventiva pública Pruebas de Toxicidad Toxicity Tests Saliva Drogas ilicitas Diagnostico Análisis Detección de abuso de sustancias Saliva Illicit drugs Diagnosis Analysis Substance abuse detection
title_short	La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura
title_full	La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura
title_fullStr	La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura
title_full_unstemmed	La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura
title_sort	La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura
dc.creator.fl_str_mv	Hernandez Tilaguy, Lorena Sofia
dc.contributor.advisor.none.fl_str_mv	Chaves Silva, Diana Carolina
dc.contributor.author.none.fl_str_mv	Hernandez Tilaguy, Lorena Sofia
dc.contributor.researchgroup.spa.fl_str_mv	Sustancias Psicoactivas
dc.subject.ddc.spa.fl_str_mv	610 - Medicina y salud::614 - Medicina Forense; incidencia de lesiones, heridas, enfermedades; medicina preventiva pública
topic	610 - Medicina y salud::614 - Medicina Forense; incidencia de lesiones, heridas, enfermedades; medicina preventiva pública Pruebas de Toxicidad Toxicity Tests Saliva Drogas ilicitas Diagnostico Análisis Detección de abuso de sustancias Saliva Illicit drugs Diagnosis Analysis Substance abuse detection
dc.subject.other.spa.fl_str_mv	Pruebas de Toxicidad
dc.subject.other.eng.fl_str_mv	Toxicity Tests
dc.subject.proposal.spa.fl_str_mv	Saliva Drogas ilicitas Diagnostico Análisis Detección de abuso de sustancias
dc.subject.proposal.eng.fl_str_mv	Saliva Illicit drugs Diagnosis Analysis Substance abuse detection
description	ilustraciones, graficas
publishDate	2022
dc.date.accessioned.none.fl_str_mv	2022-06-28T16:31:58Z
dc.date.available.none.fl_str_mv	2022-06-28T16:31:58Z
dc.date.issued.none.fl_str_mv	2022
dc.type.spa.fl_str_mv	Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv	Text
dc.type.redcol.spa.fl_str_mv	http://purl.org/redcol/resource_type/TM
status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/81634
dc.identifier.instname.spa.fl_str_mv	Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv	https://repositorio.unal.edu.co/
url	https://repositorio.unal.edu.co/handle/unal/81634 https://repositorio.unal.edu.co/
identifier_str_mv	Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv	spa
language	spa
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spelling	Reconocimiento 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Chaves Silva, Diana Carolina20e776318a9d5628459c32150f5783c2Hernandez Tilaguy, Lorena Sofia6ae17d62e5f6d47a308c040e98b938c1Sustancias Psicoactivas2022-06-28T16:31:58Z2022-06-28T16:31:58Z2022https://repositorio.unal.edu.co/handle/unal/81634Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, graficasEl incremento en el consumo de drogas de abuso es una problemática mundial que afecta negativamente, no solo a la persona que decide consumir sino también a su entorno, la gran dificultad social que desencadena dicho consumo estimula a la comunidad científica a investigar sobre metodologías que ayuden a la detección de dichas sustancias. La detección de drogas de abuso en saliva es un tema que no cuenta con información detallada y consensuada, presentándose la necesidad de dar a conocer dichas metodologías con el fin de aportar evidencia científica que pueda ser usada en diferentes ámbitos poblacionales. El presente estudio tuvo como objetivo evaluar mediante una revisión sistemática los parámetros de desempeño analítico que presentan las pruebas de detección de drogas de abuso en saliva, mediante una búsqueda en las bases de datos: Pubmed, Scielo, Scopus, CINALH, Cochrane library, Redalyc y Doaj,, se tuvieron en cuenta artículos científicos (de tipo experimental, in vitro, in vivo, poblacional) con estudios de las drogas de abuso clásicas como: THC, cocaína, anfetaminas, benzodiacepinas y sobre nuevas sustancias psicoactivas. Se incluyeron 69 artículos de los últimos 10 años en los resultados y discusión donde se abarcó la toxicocinética de las drogas en saliva, se comparó dicha toxicocinética con otras matrices de análisis, se abarcaron los métodos de detección y los factores que influyen en la detección. Se concluye que la saliva es de utilidad en la detección de las drogas de abuso estudiadas tras un consumo agudo, sin embargo, se debe tener en cuenta diferentes variables que influyen en la detección de cada tipo de droga. (Texto tomado de la fuente)The increase in the consumption of drugs of abuse is a global problem that adversely affects not only the person who decides to consume but also their environment, the great social difficulty that triggers such consumption stimulates the scientific community to investigate methodologies that help to the detection of these substances. The detection of drugs of abuse in saliva it is a topic that does not have detailed and consensual information, presenting the need to publicize these methodologies to provide scientific evidence that can be used in different population settings. The objective of this study was to evaluate, through a systematic review, the analytical performance parameters presented by the tests for the detection of drugs of abuse in saliva, through a search in the following databases: Pubmed, Scielo, Scopus, CINALH, Cochrane library, Redalyc and Doaj,, scientific articles (experimental, in vitro, in vivo, population) were taken into account with studies of classic drugs of abuse such as: THC, cocaine, amphetamines, benzodiazepines and on novel psychoactive substances. 69 articles from the last 10 years were included in the results and discussion where the toxicokinetic of drugs in saliva were covered, said toxicokinetic was compared with other analysis samples, detection methods and factors that influence detection were covered. It is concluded that saliva is useful in the detection of drugs of abuse studied after acute consumption, however, different variables that influence the detection of each type of drug must be considered.MaestríaMagíster en ToxicologíaSustancias Psicoactivasxvi, 112 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Maestría en ToxicologíaDepartamento de ToxicologíaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::614 - Medicina Forense; incidencia de lesiones, heridas, enfermedades; medicina preventiva públicaPruebas de ToxicidadToxicity TestsSalivaDrogas ilicitasDiagnosticoAnálisisDetección de abuso de sustanciasSalivaIllicit drugsDiagnosisAnalysisSubstance abuse detectionLa saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literaturaSaliva as an alternative for the detection of drugs of abuse: a systematic review of the literatureTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMAccioni, F., Nieddu, M., Corona, P., & Boatto, G. 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Auxiliar de diagnóstico. https://doi.org/10.22201/fesz.9786070299780e.2018EstudiantesInvestigadoresMaestrosPúblico generalORIGINAL1026581820.2022.pdf1026581820.2022.pdfTesis de Maestría en Toxicologíaapplication/pdf1630694https://repositorio.unal.edu.co/bitstream/unal/81634/1/1026581820.2022.pdfa428bdf1822ae6a10e585967106d51c6MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-84074https://repositorio.unal.edu.co/bitstream/unal/81634/2/license.txt8153f7789df02f0a4c9e079953658ab2MD52THUMBNAIL1026581820.2022.pdf.jpg1026581820.2022.pdf.jpgGenerated Thumbnailimage/jpeg4792https://repositorio.unal.edu.co/bitstream/unal/81634/3/1026581820.2022.pdf.jpg26c391958f84ae6b2bd16c358278265aMD53unal/81634oai:repositorio.unal.edu.co:unal/816342023-08-05 23:04:03.998Repositorio Institucional Universidad Nacional de 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La saliva como alternativa para la detección de drogas de abuso: una revisión sistemática de la literatura

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