Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018

Tramadol is an analgesic family of opioids, which has monoaminergic effects on its mechanism of action. In Colombia this is regulated with medical establishing sale with medical prescription; although this has been reported consumption purposes including recreation, as I express the United Nations O...

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Autores:
Gutiérrez Salamanca, Loren Marcela
Tipo de recurso:
Work document
Fecha de publicación:
2020
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/75628
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https://repositorio.unal.edu.co/handle/unal/75628
Palabra clave:
Toxicología
Tramadol
Post mortem
Toxicología
Epidemiologia
Forense
Tramadol
Post mortem
Toxicology
Epidemiology
Forensic
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id UNACIONAL2_5b1ddabf770a6d2c6e640a94e3ea1442
oai_identifier_str oai:repositorio.unal.edu.co:unal/75628
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018
title Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018
spellingShingle Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018
Toxicología
Tramadol
Post mortem
Toxicología
Epidemiologia
Forense
Tramadol
Post mortem
Toxicology
Epidemiology
Forensic
title_short Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018
title_full Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018
title_fullStr Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018
title_full_unstemmed Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018
title_sort Caracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018
dc.creator.fl_str_mv Gutiérrez Salamanca, Loren Marcela
dc.contributor.advisor.spa.fl_str_mv Quevedo Buitrago, Giovanni
González Urrego, Ana Georgina
dc.contributor.author.spa.fl_str_mv Gutiérrez Salamanca, Loren Marcela
dc.contributor.researchgroup.spa.fl_str_mv En sustancias psicoactivas
dc.subject.ddc.spa.fl_str_mv Toxicología
topic Toxicología
Tramadol
Post mortem
Toxicología
Epidemiologia
Forense
Tramadol
Post mortem
Toxicology
Epidemiology
Forensic
dc.subject.proposal.spa.fl_str_mv Tramadol
Post mortem
Toxicología
Epidemiologia
Forense
dc.subject.proposal.eng.fl_str_mv Tramadol
Post mortem
Toxicology
Epidemiology
Forensic
description Tramadol is an analgesic family of opioids, which has monoaminergic effects on its mechanism of action. In Colombia this is regulated with medical establishing sale with medical prescription; although this has been reported consumption purposes including recreation, as I express the United Nations Office on Drugs and Crime, in its World Report 2018 in Africa. For this reason we sought to characterize epidemiologically fatal cases with positive report for tramadol attended by the National Institute of Legal Medicine and Forensic Sciences, Bogotá, between 2013 and 2018, through a cross-sectional study. Thus a total of 35 cases, of which most are occupationally active adults and male was obtained. In fact, 40,00% had cause of death tramadol intoxication, in any of its various presentations. Added to this, 25,71% of the samples showed any laboratory other substance present. By contrast, the existence of the above 3 cases of minors who had an accidental with consumption due to mistakes in handling the drug is observed.
publishDate 2020
dc.date.accessioned.spa.fl_str_mv 2020-02-18T12:48:50Z
dc.date.available.spa.fl_str_mv 2020-02-18T12:48:50Z
dc.date.issued.spa.fl_str_mv 2020-02-14
dc.type.spa.fl_str_mv Documento de trabajo
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/workingPaper
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_8042
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/WP
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dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/75628
url https://repositorio.unal.edu.co/handle/unal/75628
dc.language.iso.spa.fl_str_mv spa
language spa
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spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de ColombiaAcceso abiertohttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Quevedo Buitrago, Giovanniad16546d-2f6b-4027-b72d-47b7778ffaca-1González Urrego, Ana Georgina21b623f5-9827-444e-80b1-e9a47858bdf5-1Gutiérrez Salamanca, Loren Marcela894d8c3f-7a35-4d2d-9884-308dd5de2de1En sustancias psicoactivas2020-02-18T12:48:50Z2020-02-18T12:48:50Z2020-02-14https://repositorio.unal.edu.co/handle/unal/75628Tramadol is an analgesic family of opioids, which has monoaminergic effects on its mechanism of action. In Colombia this is regulated with medical establishing sale with medical prescription; although this has been reported consumption purposes including recreation, as I express the United Nations Office on Drugs and Crime, in its World Report 2018 in Africa. For this reason we sought to characterize epidemiologically fatal cases with positive report for tramadol attended by the National Institute of Legal Medicine and Forensic Sciences, Bogotá, between 2013 and 2018, through a cross-sectional study. Thus a total of 35 cases, of which most are occupationally active adults and male was obtained. In fact, 40,00% had cause of death tramadol intoxication, in any of its various presentations. Added to this, 25,71% of the samples showed any laboratory other substance present. By contrast, the existence of the above 3 cases of minors who had an accidental with consumption due to mistakes in handling the drug is observed.El tramadol es un analgésico de la familia de los opioides, con efectos monoaminérgicos en su mecanismo de acción. En Colombia el medicamento se encuentra regulado estableciéndose su venta con fórmula médica; a pesar de esto se han descrito casos de consumo con fines diferentes al control del dolor, como lo es el recreativo, como lo expresó United Nations Office on Drugs and Crime, en su reporte mundial del 2018 en África. Por esta razón se buscó caracterizar epidemiológicamente los casos fatales con reporte positivo para tramadol atendidos por el Instituto Nacional de Medicina Legal y Ciencias Forenses, Sede Bogotá, entre los años del 2013 y 2018, por medio de un estudio de corte transversal, obteniendo un total de 35 casos, correspondiendo su mayoría adultos activos laboralmente y de sexo masculino. Por otra parte, el 40,00% de los individuos tenían como causa de muerte la intoxicación con tramadol, en alguna de sus diferentes presentaciones. Sumado a esto, el 25,71% de las muestras de laboratorio mostraban algún otro tipo de sustancia presente en el análisis toxicológico. En contraste a lo anterior, se observa la existencia de 3 casos de menores de edad quienes presentaron un con consumo accidental, debido a errores en el manejo o disposición del medicamento.Este proyecto se realiza en colaboración con el Instituto Nacional de Medicina Legal y Ciencias ForensesMagister en Toxicología. Línea de Investigación:Comportamiento de las Variables Sociales Relacionadas con el Consumo de Sustancias Psicoactivas.152application/pdfspaToxicologíaTramadolPost mortemToxicologíaEpidemiologiaForenseTramadolPost mortemToxicologyEpidemiologyForensicCaracterización epidemiológica de los casos fatales con reporte positivo para Tramadol atendidos por el instituto nacional de medicina legal y ciencias forenses, sede Bogotá, entre 2013 Y 2018Documento de trabajoinfo:eu-repo/semantics/workingPaperinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_8042Texthttp://purl.org/redcol/resource_type/WPUniversidad Nacional de Colombia - Sede BogotáUniversidad Nacional de Colombia - Sede Bogotá1. Ministerio de Justicia y del Derecho-Observatorio de Drogas de Colombia. Alerta informativa acerca del uso de sustancias y preparados con actividad psicoactiva utilizadas para el manejo del dolor (opioides) [Internet]. Sistema de Alerta Tempranas. 2019. p. 1–8. Available from: http://www.odc.gov.co/Portals/1/SAT/Alerta Opioides.pdf 2. United Nations Office on Drugs and Crime (UNODC). Global overview of drug demand and supply. In: World Drug Report 2018 [Internet]. 2017. p. 1–66. Available from: https://www.un-ilibrary.org/drugs-crime-and-terrorism/world-drug-report-2017_bdc264f4-en 3. United Nations Office on Drugs and Crime (UNODC). Analysis of drug markets. In: (United Nations publication, Sales No E18XI9) [Internet]. 2018. p. 1–72. Available from: https://www.unodc.org/wdr2018 4. Bravo L, Mico JA, Berrocoso E. Discovery and development of tramadol for the treatment of pain. Expert Opin Drug Discov [Internet]. 2017 Dec 2;12(12):1281–91. Available from: https://doi.org/10.1080/17460441.2017.1377697 5. Häkkinen M, Vuori E, Ojanperä I. Prescription opioid abuse based on representative postmortem toxicology. Forensic Sci Int [Internet]. 2014 Dec;245:121–5. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0379073814004435 6. 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Available from: https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-evaluating-risks-using-pain-medicine-tramadol-children-aged-17-andORIGINAL1032402030.2020.pdf1032402030.2020.pdfapplication/pdf1354805https://repositorio.unal.edu.co/bitstream/unal/75628/1/1032402030.2020.pdfbe448423231861f0c6cc3f379c49d332MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-83991https://repositorio.unal.edu.co/bitstream/unal/75628/2/license.txt6f3f13b02594d02ad110b3ad534cd5dfMD52CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8701https://repositorio.unal.edu.co/bitstream/unal/75628/3/license_rdf42fd4ad1e89814f5e4a476b409eb708cMD53THUMBNAIL1032402030.2020.pdf.jpg1032402030.2020.pdf.jpgGenerated Thumbnailimage/jpeg4766https://repositorio.unal.edu.co/bitstream/unal/75628/4/1032402030.2020.pdf.jpgded6e71502e55a1c6f6686d54c683005MD54unal/75628oai:repositorio.unal.edu.co:unal/756282023-02-28 23:08:04.913Repositorio Institucional Universidad Nacional 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