Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón
ilustraciones, diagramas, fotografías, tablas
- Autores:
-
Cuaspud Ruiz, Cristian Dario
- Tipo de recurso:
- Fecha de publicación:
- 2024
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/86942
- Palabra clave:
- 530 - Física
610 - Medicina y salud::615 - Farmacología y terapéutica
610 - Medicina y salud::616 - Enfermedades
Carga Corporal (Radioterapia)
Neoplasias Pulmonares
Evaluación Preclínica de Medicamentos
Body Burden
Lung Neoplasms
Drug Evaluation, Preclinical
SBRT pulmonar
Algoritmo Analítico Anisotrópico
Acuros XB
VeriQA
SciMoCa
TPS Eclipse
E2E
WL
Lung SBRT
Anisotropic Analytical Algorithm
Acuros XB
VeriQA
- Rights
- openAccess
- License
- Reconocimiento 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón |
| dc.title.translated.eng.fl_str_mv |
Dosimetric validation of plans stereotactic radiotherapy in cancer lung |
| title |
Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón |
| spellingShingle |
Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón 530 - Física 610 - Medicina y salud::615 - Farmacología y terapéutica 610 - Medicina y salud::616 - Enfermedades Carga Corporal (Radioterapia) Neoplasias Pulmonares Evaluación Preclínica de Medicamentos Body Burden Lung Neoplasms Drug Evaluation, Preclinical SBRT pulmonar Algoritmo Analítico Anisotrópico Acuros XB VeriQA SciMoCa TPS Eclipse E2E WL Lung SBRT Anisotropic Analytical Algorithm Acuros XB VeriQA |
| title_short |
Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón |
| title_full |
Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón |
| title_fullStr |
Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón |
| title_full_unstemmed |
Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón |
| title_sort |
Validación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmón |
| dc.creator.fl_str_mv |
Cuaspud Ruiz, Cristian Dario |
| dc.contributor.advisor.spa.fl_str_mv |
Torres Forero, Adriana Marcela Plazas de Pinzón, Maria Cristina |
| dc.contributor.author.spa.fl_str_mv |
Cuaspud Ruiz, Cristian Dario |
| dc.subject.ddc.spa.fl_str_mv |
530 - Física 610 - Medicina y salud::615 - Farmacología y terapéutica 610 - Medicina y salud::616 - Enfermedades |
| topic |
530 - Física 610 - Medicina y salud::615 - Farmacología y terapéutica 610 - Medicina y salud::616 - Enfermedades Carga Corporal (Radioterapia) Neoplasias Pulmonares Evaluación Preclínica de Medicamentos Body Burden Lung Neoplasms Drug Evaluation, Preclinical SBRT pulmonar Algoritmo Analítico Anisotrópico Acuros XB VeriQA SciMoCa TPS Eclipse E2E WL Lung SBRT Anisotropic Analytical Algorithm Acuros XB VeriQA |
| dc.subject.decs.spa.fl_str_mv |
Carga Corporal (Radioterapia) Neoplasias Pulmonares Evaluación Preclínica de Medicamentos |
| dc.subject.decs.eng.fl_str_mv |
Body Burden Lung Neoplasms Drug Evaluation, Preclinical |
| dc.subject.proposal.spa.fl_str_mv |
SBRT pulmonar Algoritmo Analítico Anisotrópico Acuros XB VeriQA SciMoCa TPS Eclipse E2E WL |
| dc.subject.proposal.eng.fl_str_mv |
Lung SBRT Anisotropic Analytical Algorithm Acuros XB VeriQA |
| description |
ilustraciones, diagramas, fotografías, tablas |
| publishDate |
2024 |
| dc.date.accessioned.none.fl_str_mv |
2024-10-15T12:56:16Z |
| dc.date.available.none.fl_str_mv |
2024-10-15T12:56:16Z |
| dc.date.issued.none.fl_str_mv |
2024 |
| dc.type.spa.fl_str_mv |
Trabajo de grado - Maestría |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/masterThesis |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
| dc.type.content.spa.fl_str_mv |
Text |
| dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/TM |
| status_str |
acceptedVersion |
| dc.identifier.uri.none.fl_str_mv |
https://repositorio.unal.edu.co/handle/unal/86942 |
| dc.identifier.instname.spa.fl_str_mv |
Universidad Nacional de Colombia |
| dc.identifier.reponame.spa.fl_str_mv |
Repositorio Institucional Universidad Nacional de Colombia |
| dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.unal.edu.co/ |
| url |
https://repositorio.unal.edu.co/handle/unal/86942 https://repositorio.unal.edu.co/ |
| identifier_str_mv |
Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
| dc.language.iso.spa.fl_str_mv |
spa |
| language |
spa |
| dc.relation.references.spa.fl_str_mv |
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Reconocimiento 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Torres Forero, Adriana Marcela6d7ce06184e2539ca834825261fd8a89Plazas de Pinzón, Maria Cristinab91ad651f3859d1aa80f6a452771c039Cuaspud Ruiz, Cristian Darioc6b9e7ad822dec8edaed75f930a9ad4b2020-20232024-10-15T12:56:16Z2024-10-15T12:56:16Z2024https://repositorio.unal.edu.co/handle/unal/86942Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramas, fotografías, tablasEste trabajo presenta un análisis de los aspectos dosimétricos en planes de tratamiento de Radioterapia Corporal Estereotáctica de cáncer de pulmón, realizados utilizando el sistema de planificación de tratamiento Eclipse. Estos planes fueron calculados con el Algoritmo Analítico Anisotrópico y el algoritmo Acuros XB, y entregados en el acelerador lineal Halcyon de Varian. Se llevó a cabo un estudio de casos de tipo experimental, utilizando imágenes tomográficas de pacientes que ya han recibido SBRT pulmonar. La población de estudio consistió en imágenes tomográficas de registros de planeaciones de SBRT pulmonar de pacientes con NSCLC en etapa temprana, tratados entre los años 2020 y 2023. Se evaluaron e implementan métodos que permitan disminuir imprecisiones que se generan en el flujo clínico de los tratamientos en el Servicio de Radioterapia del Instituto Médico Oncológico S.A.S. Estos métodos incluyeron validaciones dosimétricas mediante cálculos independientes con el algoritmo SciMoCa del software VeriQA de PTW, comprobaciones de entrega de dosis utilizando el sistema para control de paciente específico Octavius 4D de PTW, la automatización del cálculo de índices dosimétricos para la evaluación clínica de los planes mediante un script implementado en la interfaz de programación de aplicaciones de Eclipse. También, se determinó el impacto del simulador físico Ruby de PTW en la realización de pruebas de extremo a extremo y la prueba Winston Lutz. Finalmente, se implementó un código en el lenguaje de programación Python que utiliza la librería PyLinac para el análisis de la prueba Winston Lutz. Los resultados ofrecen beneficios significativos en el desarrollo de un flujo clínico con mayor precisión en la entrega de dosis, reducción de los tiempos de planificación y optimización de los recursos disponibles (Texto tomado de la fuente).This work presents an analysis of dosimetric aspects in stereotactic body radiotherapy treatment plans for lung cancer, performed using the Eclipse Treatment Planning System. These plans were calculated with the Anisotropic Analytical Algorithm and the Acuros XB algorithm, and delivered on the Varian Halcyon linear accelerator. An experimental case study was carried out, utilizing tomographic images of patients who had already undergone SBRT for lung cancer. The study population consisted of tomographic images from lung SBRT planning records of patients with early-stage NSCLC, treated between the years 2020 and 2023. Methods were evaluated and implemented to reduce inaccuracies that occur in the clinical workflow of treatments at the Radiotherapy Service of the Instituto Medico Oncologico S.A.S. These methods included dosimetric validations through independent calculations with the SciMoCa algorithm from PTW’s VeriQA software, dose delivery verifications using PTW’s patient-specific QA system Octavius 4D, automation of dosimetric index calculations for clinical plan evaluation through a script implemented in the Eclipse Scripting Application Programming Interface. Additionally, the impact of PTW’s Ruby physical simulator on the execution of end-to-end tests and the Winston Lutz test was assessed. Finally, a Python code was implemented using the PyLinac library for the analysis of the Winston Lutz test. The results offer significant benefits in the development of a clinical workflow with greater accuracy in dose delivery, reduction in planning times, and optimization of available resources.MaestríaMagíster en Física MédicaSe realizó un estudio de casos de tipo experimental utilizando imágenes tomografícas de pacientes que han recibido SBRT pulmonar. El estudio se centra en una validación dosimétrica de los planes calculados en el TPS Eclipse de Varian con los algoritmos AAA y AXB, mediante cálculos independientes realizados con el algoritmo SciMoCa del software VeriQA de PTW. Además, se evalúan métodos para mejorar aspectos en el flujo clínico de los tratamientos de SBRT pulmonar en el Servicio de Radioterapia del Instituto Médico Oncológico S.A.S, incluyeno el control de paciente especifico con el sistema Octavius de PTW, el impacto del simulador físico Ruby de PTW en la ejecución de pruebas de extremo a extremo y Winston Lutz, y la evaluación de los planes con un script que permite la obtención de índices dosimétricos.Radioterapia135 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Ciencias - Maestría en Física MédicaFacultad de CienciasBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá530 - Física610 - Medicina y salud::615 - Farmacología y terapéutica610 - Medicina y salud::616 - EnfermedadesCarga Corporal (Radioterapia)Neoplasias PulmonaresEvaluación Preclínica de MedicamentosBody BurdenLung NeoplasmsDrug Evaluation, PreclinicalSBRT pulmonarAlgoritmo Analítico AnisotrópicoAcuros XBVeriQASciMoCaTPS EclipseE2EWLLung SBRTAnisotropic Analytical AlgorithmAcuros XBVeriQAValidación dosimétrica de planes de radioterapia estereotáctica en cáncer de pulmónDosimetric validation of plans stereotactic radiotherapy in cancer lungTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TM[1] National Cancer Institute - USA, “Radiation Therapy to Treat Cancer”. 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