Molecular mechanisms of autophagy and its role in cancer development

Autophagy is an evolutionary process preserved in eukaryotes, which removes harmful components and maintains cell homeostasis in response to a variety of extracellular stimuli. It is involved in both physiological and pathological conditions, including cancer.The role of autophagy in the treatment o...

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Autores:: Salazar-Ramírez, Kathleen
Molinares-Rodríguez, Jhonny
Bolívar-González, Samir

Tipo de recurso:: Article of journal

Fecha de publicación:: 2016

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: spa

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dc.title.spa.fl_str_mv	Molecular mechanisms of autophagy and its role in cancer development
title	Molecular mechanisms of autophagy and its role in cancer development
spellingShingle	Molecular mechanisms of autophagy and its role in cancer development 61 Ciencias médicas; Medicina / Medicine and health Autophagy Cancer Tumorigenesis Proliferation Autofagia Cáncer Tumorigénesis Proliferación
title_short	Molecular mechanisms of autophagy and its role in cancer development
title_full	Molecular mechanisms of autophagy and its role in cancer development
title_fullStr	Molecular mechanisms of autophagy and its role in cancer development
title_full_unstemmed	Molecular mechanisms of autophagy and its role in cancer development
title_sort	Molecular mechanisms of autophagy and its role in cancer development
dc.creator.fl_str_mv	Salazar-Ramírez, Kathleen Molinares-Rodríguez, Jhonny Bolívar-González, Samir
dc.contributor.author.spa.fl_str_mv	Salazar-Ramírez, Kathleen Molinares-Rodríguez, Jhonny Bolívar-González, Samir
dc.subject.ddc.spa.fl_str_mv	61 Ciencias médicas; Medicina / Medicine and health
topic	61 Ciencias médicas; Medicina / Medicine and health Autophagy Cancer Tumorigenesis Proliferation Autofagia Cáncer Tumorigénesis Proliferación
dc.subject.proposal.spa.fl_str_mv	Autophagy Cancer Tumorigenesis Proliferation Autofagia Cáncer Tumorigénesis Proliferación
description	Autophagy is an evolutionary process preserved in eukaryotes, which removes harmful components and maintains cell homeostasis in response to a variety of extracellular stimuli. It is involved in both physiological and pathological conditions, including cancer.The role of autophagy in the treatment of cancer is described as a “double-edged sword”, which reflects its involvement in tumor suppression, survival and subsequent proliferation of tumor cells. Recent advances are useful for planning appropriate adjustments to inhibit or promote autophagy in order to obtain therapeutic efficacy in cancer patients. The objectives of this review are to clarify the role of autophagy in cancer and to highlight the need for more research in the field.
publishDate	2016
dc.date.issued.spa.fl_str_mv	2016-07-01
dc.date.accessioned.spa.fl_str_mv	2019-07-02T23:58:36Z
dc.date.available.spa.fl_str_mv	2019-07-02T23:58:36Z
dc.type.spa.fl_str_mv	Artículo de revista
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dc.identifier.issn.spa.fl_str_mv	ISSN: 2357-3848
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identifier_str_mv	ISSN: 2357-3848
url	https://repositorio.unal.edu.co/handle/unal/65199 http://bdigital.unal.edu.co/66222/
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dc.relation.spa.fl_str_mv	https://revistas.unal.edu.co/index.php/revfacmed/article/view/54152
dc.relation.ispartof.spa.fl_str_mv	Universidad Nacional de Colombia Revistas electrónicas UN Revista de la Facultad de Medicina Revista de la Facultad de Medicina
dc.relation.references.spa.fl_str_mv	Salazar-Ramírez, Kathleen and Molinares-Rodríguez, Jhonny and Bolívar-González, Samir (2016) Molecular mechanisms of autophagy and its role in cancer development. Revista de la Facultad de Medicina, 64 (3). pp. 529-535. ISSN 2357-3848
dc.rights.spa.fl_str_mv	Derechos reservados - Universidad Nacional de Colombia
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dc.publisher.spa.fl_str_mv	Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina
institution	Universidad Nacional de Colombia
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Molecular mechanisms of autophagy and its role in cancer development

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