Hypertriglyceridemia and adverse outcomes during pregnancy

Introduction: During pregnancy, levels of maternal serum triglycerides increase as a physiological adaptation mechanism to meet the needs of the developing fetus. However, although an excessive increase has been associated with preeclampsia, macrosomia and preterm delivery, the levels from which mea...

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Autores:
Cortés-Vásquez, Jonathan
Noreña, Islendy
Mockus, Ismena
Tipo de recurso:
Article of journal
Fecha de publicación:
2018
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/64958
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/64958
http://bdigital.unal.edu.co/65981/
Palabra clave:
61 Ciencias médicas; Medicina / Medicine and health
Embarazo
Hipertrigliceridemia
Intercambio materno-fetal
Desarrollo fetal
Complicaciones del embarazo
Pregnancy
Hypertriglyceridemia
Maternal-Fetal Exchange
Fetal Development
Pregnancy Complications
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
id UNACIONAL2_568706597ea5ed43faa6540ee6e25a74
oai_identifier_str oai:repositorio.unal.edu.co:unal/64958
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Hypertriglyceridemia and adverse outcomes during pregnancy
title Hypertriglyceridemia and adverse outcomes during pregnancy
spellingShingle Hypertriglyceridemia and adverse outcomes during pregnancy
61 Ciencias médicas; Medicina / Medicine and health
Embarazo
Hipertrigliceridemia
Intercambio materno-fetal
Desarrollo fetal
Complicaciones del embarazo
Pregnancy
Hypertriglyceridemia
Maternal-Fetal Exchange
Fetal Development
Pregnancy Complications
title_short Hypertriglyceridemia and adverse outcomes during pregnancy
title_full Hypertriglyceridemia and adverse outcomes during pregnancy
title_fullStr Hypertriglyceridemia and adverse outcomes during pregnancy
title_full_unstemmed Hypertriglyceridemia and adverse outcomes during pregnancy
title_sort Hypertriglyceridemia and adverse outcomes during pregnancy
dc.creator.fl_str_mv Cortés-Vásquez, Jonathan
Noreña, Islendy
Mockus, Ismena
dc.contributor.author.spa.fl_str_mv Cortés-Vásquez, Jonathan
Noreña, Islendy
Mockus, Ismena
dc.subject.ddc.spa.fl_str_mv 61 Ciencias médicas; Medicina / Medicine and health
topic 61 Ciencias médicas; Medicina / Medicine and health
Embarazo
Hipertrigliceridemia
Intercambio materno-fetal
Desarrollo fetal
Complicaciones del embarazo
Pregnancy
Hypertriglyceridemia
Maternal-Fetal Exchange
Fetal Development
Pregnancy Complications
dc.subject.proposal.spa.fl_str_mv Embarazo
Hipertrigliceridemia
Intercambio materno-fetal
Desarrollo fetal
Complicaciones del embarazo
Pregnancy
Hypertriglyceridemia
Maternal-Fetal Exchange
Fetal Development
Pregnancy Complications
description Introduction: During pregnancy, levels of maternal serum triglycerides increase as a physiological adaptation mechanism to meet the needs of the developing fetus. However, although an excessive increase has been associated with preeclampsia, macrosomia and preterm delivery, the levels from which measurements should be taken in each trimester to prevent complications have not been established conclusively.Objective: To review the physiopathology, effects on mother and child, expected values in each trimester and therapeutic interventions in maternal hypertriglyceridemia.Materials and methods: A review was made based on a search of articles in the ScienceDirect, Pubmed, Scopus, LILACS, Cochrane and SciELO databases, with the terms: Pregnancy; Hypertriglyceridemia; Maternal-Fetal Exchange; Fetal Development; Pregnancy Complications in English and its equivalents in Spanish.Results: 59 articles met the search criteria and responded to the objectives.Conclusions: The limited amount and the great variability of the data indicate the need to carry out further research to establish the normal triglycerides ranges during the three trimesters of pregnancy and to determine risks and effective interventions before pregnancy in order to reduce maternal and child morbidity and mortality.
publishDate 2018
dc.date.issued.spa.fl_str_mv 2018-04-01
dc.date.accessioned.spa.fl_str_mv 2019-07-02T23:37:12Z
dc.date.available.spa.fl_str_mv 2019-07-02T23:37:12Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.issn.spa.fl_str_mv ISSN: 2357-3848
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/64958
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identifier_str_mv ISSN: 2357-3848
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dc.relation.ispartof.spa.fl_str_mv Universidad Nacional de Colombia Revistas electrónicas UN Revista de la Facultad de Medicina
Revista de la Facultad de Medicina
dc.relation.references.spa.fl_str_mv Cortés-Vásquez, Jonathan and Noreña, Islendy and Mockus, Ismena (2018) Hypertriglyceridemia and adverse outcomes during pregnancy. Revista de la Facultad de Medicina, 66 (2). pp. 247-253. ISSN 2357-3848
dc.rights.spa.fl_str_mv Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
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dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
Derechos reservados - Universidad Nacional de Colombia
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina
institution Universidad Nacional de Colombia
bitstream.url.fl_str_mv https://repositorio.unal.edu.co/bitstream/unal/64958/1/60791-389463-1-PB.pdf
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spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Cortés-Vásquez, Jonathan52f66cff-1057-4de3-92c3-2b5f538b3a55300Noreña, Islendy9a22cde5-c494-4fad-a1f4-ccc1e51c47fd300Mockus, Ismena957c0e44-08e5-4849-b52a-7a1218d0deda3002019-07-02T23:37:12Z2019-07-02T23:37:12Z2018-04-01ISSN: 2357-3848https://repositorio.unal.edu.co/handle/unal/64958http://bdigital.unal.edu.co/65981/Introduction: During pregnancy, levels of maternal serum triglycerides increase as a physiological adaptation mechanism to meet the needs of the developing fetus. However, although an excessive increase has been associated with preeclampsia, macrosomia and preterm delivery, the levels from which measurements should be taken in each trimester to prevent complications have not been established conclusively.Objective: To review the physiopathology, effects on mother and child, expected values in each trimester and therapeutic interventions in maternal hypertriglyceridemia.Materials and methods: A review was made based on a search of articles in the ScienceDirect, Pubmed, Scopus, LILACS, Cochrane and SciELO databases, with the terms: Pregnancy; Hypertriglyceridemia; Maternal-Fetal Exchange; Fetal Development; Pregnancy Complications in English and its equivalents in Spanish.Results: 59 articles met the search criteria and responded to the objectives.Conclusions: The limited amount and the great variability of the data indicate the need to carry out further research to establish the normal triglycerides ranges during the three trimesters of pregnancy and to determine risks and effective interventions before pregnancy in order to reduce maternal and child morbidity and mortality.Introducción. Durante el embarazo, los niveles séricos de triglicéridos maternos aumentan como un mecanismo de adaptación fisiológica para suplir las necesidades del feto en desarrollo. Pese a que el incremento excesivo se ha asociado a preeclampsia, macrosomía y parto pretérmino, no se han establecido de manera contundente los niveles a partir de los cuales se deben tomar medidas en cada trimestre para prevenir complicaciones.Objetivo. Hacer una revisión sobre fisiopatología, efectos en madre e hijo, valores esperados en cada trimestre e intervenciones terapéuticas en hipertrigliceridemia gestacional.Materiales y métodos. Se realizó una revisión con la búsqueda de artículos en las bases de datos ScienceDirect, PubMed, Scopus, LILACS, Cochrane y SciELO con los términos: Pregnancy; Hypertriglyceridemia; Maternal-Fetal Exchange; Fetal Development; Pregnancy Complications y sus equivalentes en español.Resultados. Se encontraron 59 artículos que cumplieron los criterios de búsqueda y daban respuesta a los objetivos.Conclusiones. El número limitado y la gran variabilidad de los datos indican la necesidad de realizar más investigaciones que establezcan los rangos de normalidad de los triglicéridos durante los tres trimestres del embarazo y así determinar riesgos e intervenciones eficaces antes de la gestación y reducir la morbimortalidad materno-infantil.application/pdfspaUniversidad Nacional de Colombia - Sede Bogotá - Facultad de Medicinahttps://revistas.unal.edu.co/index.php/revfacmed/article/view/60791Universidad Nacional de Colombia Revistas electrónicas UN Revista de la Facultad de MedicinaRevista de la Facultad de MedicinaCortés-Vásquez, Jonathan and Noreña, Islendy and Mockus, Ismena (2018) Hypertriglyceridemia and adverse outcomes during pregnancy. Revista de la Facultad de Medicina, 66 (2). pp. 247-253. ISSN 2357-384861 Ciencias médicas; Medicina / Medicine and healthEmbarazoHipertrigliceridemiaIntercambio materno-fetalDesarrollo fetalComplicaciones del embarazoPregnancyHypertriglyceridemiaMaternal-Fetal ExchangeFetal DevelopmentPregnancy ComplicationsHypertriglyceridemia and adverse outcomes during pregnancyArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTORIGINAL60791-389463-1-PB.pdfapplication/pdf605814https://repositorio.unal.edu.co/bitstream/unal/64958/1/60791-389463-1-PB.pdfaeda02198a69113a2310b0ef8ed320b0MD51THUMBNAIL60791-389463-1-PB.pdf.jpg60791-389463-1-PB.pdf.jpgGenerated Thumbnailimage/jpeg8142https://repositorio.unal.edu.co/bitstream/unal/64958/2/60791-389463-1-PB.pdf.jpgdbbfcfe125bde5f22669e0a265fde73dMD52unal/64958oai:repositorio.unal.edu.co:unal/649582023-04-28 23:05:46.507Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co