Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida
ilustraciones, gráficas, tablas
- Autores:
-
Bedoya Morales, Ana Maritza
- Tipo de recurso:
- Fecha de publicación:
- 2021
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/80888
- Palabra clave:
- 610 - Medicina y salud
Salud del Niño
Epilepsia/cirugía
Comodidad del Paciente
Child Health
Epilepsy/surgery
Patient Comfort
Epilepsia
Pediatría
Cirugía de epilepsia
Calidad de vida
Epilepsy
Pediatrics
Epilepsy surgery
Quality of life
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
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Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida |
| dc.title.translated.eng.fl_str_mv |
Characterization of pediatric patients before and after epilepsy surgery: a focus on quality of life |
| title |
Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida |
| spellingShingle |
Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida 610 - Medicina y salud Salud del Niño Epilepsia/cirugía Comodidad del Paciente Child Health Epilepsy/surgery Patient Comfort Epilepsia Pediatría Cirugía de epilepsia Calidad de vida Epilepsy Pediatrics Epilepsy surgery Quality of life |
| title_short |
Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida |
| title_full |
Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida |
| title_fullStr |
Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida |
| title_full_unstemmed |
Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida |
| title_sort |
Caracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vida |
| dc.creator.fl_str_mv |
Bedoya Morales, Ana Maritza |
| dc.contributor.advisor.spa.fl_str_mv |
Uscategui Daccarett, Angélica María |
| dc.contributor.author.spa.fl_str_mv |
Bedoya Morales, Ana Maritza |
| dc.contributor.researchgroup.spa.fl_str_mv |
Neuroped-Unal |
| dc.contributor.subjectmatterexpert.spa.fl_str_mv |
Echeverria Palacio, Carlos Mario |
| dc.subject.ddc.spa.fl_str_mv |
610 - Medicina y salud |
| topic |
610 - Medicina y salud Salud del Niño Epilepsia/cirugía Comodidad del Paciente Child Health Epilepsy/surgery Patient Comfort Epilepsia Pediatría Cirugía de epilepsia Calidad de vida Epilepsy Pediatrics Epilepsy surgery Quality of life |
| dc.subject.decs.spa.fl_str_mv |
Salud del Niño Epilepsia/cirugía Comodidad del Paciente |
| dc.subject.decs.eng.fl_str_mv |
Child Health Epilepsy/surgery Patient Comfort |
| dc.subject.proposal.spa.fl_str_mv |
Epilepsia Pediatría Cirugía de epilepsia Calidad de vida |
| dc.subject.proposal.eng.fl_str_mv |
Epilepsy Pediatrics Epilepsy surgery Quality of life |
| description |
ilustraciones, gráficas, tablas |
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2021 |
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2021 |
| dc.date.accessioned.none.fl_str_mv |
2022-02-05T01:45:55Z |
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2022-02-05T01:45:55Z |
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Trabajo de grado - Especialidad Médica |
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info:eu-repo/semantics/masterThesis |
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Text |
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Universidad Nacional de Colombia |
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Repositorio Institucional Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/ |
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https://repositorio.unal.edu.co/handle/unal/80888 https://repositorio.unal.edu.co/ |
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Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
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spa |
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Neurol Clin. 2019;27(4):1003–13. The WHOQOL group. The World Health organization Quality of Life Assessment: The development and psychometric properties. Soc Sci Med. 1998;46(12):1569–85. Cross JH, Jayakar P, Nordli D, Delalande O, Duchowny M, Wieser HG, et al. Proposed criteria for referral and evaluation of children for epilepsy surgery: Recommendations of the subcommission for pediatric epilepsy surgery. Epilepsia [Internet]. 2006;47(6):952–9. Available from: http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=reference&D=emed7&NEWS=N&AN=2006257121 Larysz D, Larysz P, Mandera M. Evaluation of quality of life and clinical status of children operated on for intractable epilepsy. Child’s Nerv Syst. 2007;23(1):91–7. Ramirez R SM. Diseño de una escala para evaluar Calidad de Vida en niños y Adolescentes con epilepsia ECANIVAE-LICCE. 2015;5–27. Titus JB, Lee A, Kasasbeh A, Thio LL, Stephenson J, Steger-May K, et al. Health-related quality of life before and after pediatric epilepsy surgery: The influence of seizure outcome on changes in physical functioning and social functioning. Epilepsy Behav [Internet]. 2013;27(3):477–83. Available from: http://dx.doi.org/10.1016/j.yebeh.2013.03.003 Zupanc ML, dos Santos Rubio EJ, Werner RR, Schwabe MJ, Mueller WM, Lew SM, et al. Epilepsy Surgery Outcomes: Quality of Life and Seizure Control. Pediatr Neurol [Internet]. 2010;42(1):12–20. Available from: http://dx.doi.org/10.1016/j.pediatrneurol.2009.07.018 Janszky J, Janszky I, Schulz R, Hoppe M, Behne F, Pannek HW, et al. Temporal lobe epilepsy with hippocampal sclerosis: Predictors for long-term surgical outcome. Brain. 2005;128(2):395–404. Edelvik A, Taft C, Ekstedt G, Malmgren K. Health-related quality of life and emotional well-being after epilepsy surgery: A prospective, controlled, long-term follow-up. Epilepsia. 2017;58(10):1706–15. Reilly C, Taft C, Edelvik A, Olsson I, Malmgren K. Health-related quality of life and emotional wellbeing improve in parents after their children have undergone epilepsy surgery — A prospective population-based study. Epilepsy Behav [Internet]. 2017;75:196–202. Available from: http://dx.doi.org/10.1016/j.yebeh.2017.07.042 Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, et al. A practical clinical definition of epilepsy. 2014;1–8. Engel J. A Proposed Diagnostic Scheme for People with Epileptic Seizures and with Epilepsy: Report of the ILAE Task Force on Classification and Terminology. 2001;42(6):796–803. Scheffer IE, Berkovic S, Capovilla G, Connolly MB, French J, Guilhoto L, et al. Classification of the epilepsies : Position paper of the ILAE Commission for Classification and Terminology. 2017;512–21. Cormack F, Cross JH, Isaacs E, Harkness W, Wright I, Vargha-khadem F, et al. The Development of Intellectual Abilities in Pediatric Temporal Lobe Epilepsy. 2007;48(1):201–4. Spencer S, Huh L. Outcomes of epilepsy surgery in adults and children. Lancet Neurol. 2008;7(6):525–37. Laxer KD, Trinka E, Hirsch LJ, Cendes F, Lang J, Delanty N, et al. The consequences of refractory epilepsy and its treatment. Epilepsy Behav. 2014;37:59–70. Raspall-chaure M, Neville BG, Scott RC. The medical management of the epilepsies in children : conceptual and practical considerations. 2008;9–12. Louw E Van Der, Hurk D Van Den, Neal E, Fitzsimmon G, Dority L, Dudzi M, et al. Ketogenic diet guidelines for infants with refractory epilepsy. 2016;0. Neal EG, Chaff H, Schwartz RH, Lawson MS, Edwards N, Fitzsimmons G, et al. The ketogenic diet for the treatment of childhood epilepsy : a randomised controlled trial. 2008;7(June). Mehta V, Cd F, Jh C, Vadlamani G. Corticosteroids including ACTH for childhood epilepsy other than epileptic spasms. 2015;(6). Mbbs KHA, Mbbs ROA, Mbbs AAA, Mbbs ZHA, Mbbs SNM, Mbbs DSA, et al. Intravenous Methylprednisolone for Intractable Childhood Epilepsy. Pediatr Neurol [Internet]. 2014;50(4):334–6. Available from: http://dx.doi.org/10.1016/j.pediatrneurol.2013.12.015 Spencer SS, Berg AT, Vickrey BG, Sperling MR, Bazil CW, Haut S, et al. Health-related quality of life over time since resective epilepsy surgery. Ann Neurol. 2007;62(4):327–34. Jayakar P, Gaillard WD, Tripathi M, Libenson MH, Mathern GW, Cross JH. Diagnostic test utilization in evaluation for resective epilepsy surgery in children. Epilepsia. 2014;55(4):507–18. David B, Elger CE, Theodor R. MRI in epilepsy: clinical standard and evolution. 2018; Bernasconi A, Gill RS, Ryvlin P, Koepp MJ, Bernasconi N, Hogan RE, et al. Recommendations for the use of structural magnetic resonance imaging in the care of patients with epilepsy : A consensus report from the International League Against Epilepsy Neuroimaging Task Force. 2019;(April):1054–68. Baxendale S, Wilson SJ, Baker GA, Barr W, Helmstaedter C, Hermann BP, et al. Indications and expectations for neuropsychological assessment in epilepsy surgery in children and adults Report of the ILAE Neuropsychology Task Force Diagnostic Methods Commission : 2017-2021 Neuropsychological assessment in epilepsy surgery. 2021;21(3):674–81. Vogt VL, Äikiä M, del Barrio A, Boon P, Borbély C, Bran E, et al. Current standards of neuropsychological assessment in epilepsy surgery centers across Europe. Epilepsia. 2017;58(3):343–55. Fan H, Hsu T, Chang K, Chen S, Tsai J, Tcns VNS. Vagus nerve stimulation for 6- to 12-year-old children with refractory epilepsy : Impact on seizure frequency and parenting stress index. Epilepsy Behav [Internet]. 2018;83:119–23. Available from: https://doi.org/10.1016/j.yebeh.2017.12.009 Mikati MA, Ataya NF, El-Ferezli JC, Baghdadi TS, Turkmani AH, Comair YG, et al. Quality of life after vagal nerve stimulator insertion. Epileptic Disord. 2009;11(1):67–74. Englot DJ, Hassnain KH, Rolston JD, Harward SC, Sinha SR, Haglund MM. Quality-of-life metrics with vagus nerve stimulation for epilepsy from provider survey data. Epilepsy Behav. 2017;66(415):4–9. Elliott IM, Lach L, Lou M. I just want to be normal : A qualitative study exploring how children and adolescents view the impact of intractable epilepsy on their quality of life. 2005;7:664–78. Taft C, Sager Magnusson E, Ekstedt G, Malmgren K. Health-related quality of life, mood, and patient satisfaction after epilepsy surgery in Sweden - A prospective controlled observational study. Epilepsia. 2014;55(6):878–85. Smith JAD, Armacost M, Ensign E, Shaw S, Jimenez N, Millett D, et al. Epilepsy surgery in the underserved Hispanic population improves depression, anxiety, and quality of life. Epilepsy Behav [Internet]. 2018;83:1–6. Available from: https://doi.org/10.1016/j.yebeh.2018.03.015 Fiest KM, Sajobi TT, Wiebe S. Epilepsy surgery and meaningful improvements in quality of life: Results from a randomized controlled trial. Epilepsia. 2014;55(6):886–92. Liu S-Y, Yang X-L, Chen B, Hou Z, An N, Yang M-H, et al. Clinical Outcomes and Quality of Life Following Surgical Treatment for Refractory Epilepsy. Medicine (Baltimore). 2015;94(6):e500. Conway L, Widjaja E, Smith M Lou. Impact of resective epilepsy surgery on health-related quality of life in children with and without low intellectual ability. Epilepsy Behav [Internet]. 2018;83:131–6. Available from: https://doi.org/10.1016/j.yebeh.2018.03.036 Mikati MA, Ataya N, Ferzli J, Kurdi R, El-Banna D, Rahi A, et al. Quality of life after surgery for intractable partial epilepsy in children: A cohort study with controls. Epilepsy Res [Internet]. 2010;90(3):207–13. Available from: http://dx.doi.org/10.1016/j.eplepsyres.2010.05.002 Elliott I, Kadis DS, Lach L, Olds J, McCleary L, Whiting S, et al. Quality of life in young adults who underwent resective surgery for epilepsy in childhood. Epilepsia. 2012;53(9):1577–86. Birbeck GL, Hays RD, Cui X, Vickrey BG. Seizure reduction and quality of life improvements in people with epilepsy. Epilepsia. 2002;43(5):535–8. Puka K, Smith M Lou. Predictors of long-term quality of life after pediatric epilepsy surgery. Epilepsia. 2015;56(6):873–81. Seiam AHR, Dhaliwal H, Wiebe S. Determinants of quality of life after epilepsy surgery: Systematic review and evidence summary. Epilepsy Behav [Internet]. 2011;21(4):441–5. Available from: http://dx.doi.org/10.1016/j.yebeh.2011.05.005 Choi-Kwon S, Chung CK, Lee SK, Choi J, Han K, Lee EH. Quality of life after epilepsy surgery in Korea. J Clin Neurol. 2008;4(3):116–22. Mohammed HS, Kaufman CB, Limbrick DD, Steger-May K, Grubb RL, Rothman SM, et al. Impact of epilepsy surgery on seizure control and quality of life: A 26-year follow-up study. Epilepsia. 2012;53(4):712–20. Langfitt JT, Westerveld M, Hamberger MJ, Walczak TS, Cicchetti D V, Berg AT, et al. Worsening of quality of life after epilepsy surgery. Neurology. 2007;68(23):1988. Cousino MK, Hazen RA. Parenting Stress Among Caregivers of Children With Chronic Illness : A Systematic Review. 2013;38(8):809–28. Jones C, Reilly C. Parental anxiety in childhood epilepsy : A systematic review. 2016;57(4):529–37. Gagliardi IC, Guimarães CA, Souza EAP, Schmutzler KMR, Guerreiro MM. Quality of life and epilepsy surgery in childhood and adolescence. Arq Neuropsiquiatr [Internet]. 2011;69(1):23–6. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21359418 Karakis I, Montouris GD, Piperidou C, Luciano MS, Meador KJ, Cole AJ. The effect of epilepsy surgery on caregiver quality of life. Epilepsy Res [Internet]. 2013;107(1–2):181–9. Available from: http://dx.doi.org/10.1016/j.eplepsyres.2013.08.006 Torres X, Arroyo S, Araya S, De Pablo J. The Spanish version of the Quality-of-Life in Epilepsy Inventory (QOLIE- 31): Translation, validity, and reliability. Epilepsia. 1999;40(9):1299–304. Sabaz M, Lawson JA, Cairns DR, Duchowny MS, Resnick TJ, Dean PM, et al. Validation of the Quality of Life in Childhood Epilepsy Questionnaire in American epilepsy patients. 2003;4:680–91. Sabaz M, Cairns DR, Lawson JA, Nheu N, Bleasel AF, Bye AME. Validation of a New Quality of Life Measure for Children with Epilepsy. 2000;41(6):765–74. Sabaz M, Cairns DR, Lawson JA, Bleasel AF, Bye AME. The Health-Related Quality of Life of Children with Refractory Epilepsy : A Comparison of Those With and Without Intellectual Disability. 2001;42(5):621–8. Herranz JL, Casas C. Escala de calidad de vida del niño con epilepsia ( CAVE ). Rev Neurol. 1996;24(125):28–30. García-galicia A, García-carrasco M, Montiel-jarquín ÁJ, García-cuautitla MA, Barragán-hervella RG, Romero-figueroa MS. Validez y consistencia de las escalas ECAVIPEP y CAVE para evaluar la calidad de vida en pacientes pediátricos con epilepsia. Rev Neurol. 2014;59(7):301–6. Hosoyama H, Matsuda K, Mihara T, Usui N, Baba K, Inoue Y, et al. Long-term outcomes of epilepsy surgery in 85 pediatric patients followed up for over 10 years: a retrospective survey. J Neurosurg Pediatr. 2017;19(5):606–15. Timotheo S, Leal F, Volpon M, Thomé U, Rubens H, Escorsi-rosset S, et al. Epilepsy & Behavior Impact of epilepsy surgery on quality of life and burden of caregivers in children and adolescents. Epilepsy Behav [Internet]. 2020;106:106961. Available from: https://doi.org/10.1016/j.yebeh.2020.106961 M. S, J.A. L, D.R. C, M.S. D, T.J. R, P.M. D, et al. The impact of epilepsy surgery on quality of life in children. Neurology [Internet]. 2006;66(4):557–61. Available from: http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L43739887%5Cnhttp://dx.doi.org/10.1212/01.wnl.0000197788.38783.09%5Cnhttp://cy7sh3vq3t.search.serialssolutions.com?sid=EMBASE&sid=EMBASE&issn=00283878&id=doi:10.1212/01.wnl.000019778 Gutierrez-Angel AM, Martinez-Juarez IE, Hernandez-Vanegas LE, Crail-Melendez D. Quality of life and level of burden in primary caregivers of patients with epilepsy: Effect of neuropsychiatric comorbidity. Epilepsy Behav. 2018 Apr;81:12–7. Sajobi TT, Fiest KM, Wiebe S. Changes in quality of life after epilepsy surgery: The role of reprioritization response shift. Epilepsia. 2014;55(9):1331–8. Gallop K, Lloyd AJ, Olt J, Marshall J. Impact of developmental and epileptic encephalopathies on caregivers: A literature review. Epilepsy Behav. 2021 Nov;124:108324. Karakis C, Cole AJ, Montouris GD, Luciano MS, Meador KJ, Piperidou C, et al. Caregiver Burden in Epilepsy: Determinants and Impact. Epilepsy Res Treat. 2014 Apr;2014(1):1–9. |
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xvii, 61 páginas |
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Universidad Nacional de Colombia |
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Bogotá - Medicina - Especialidad en Neuropediatría |
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Departamento de Pediatría |
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Facultad de Medicina |
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Bogotá, Colombia |
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Universidad Nacional de Colombia - Sede Bogotá |
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Universidad Nacional de Colombia |
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Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Uscategui Daccarett, Angélica Maríabe2829b0c8f54cc9114a94eabf0dc5ba600Bedoya Morales, Ana Maritza447c5ec2f753160dd0334f28816cee26Neuroped-UnalEcheverria Palacio, Carlos Mario2022-02-05T01:45:55Z2022-02-05T01:45:55Z2021https://repositorio.unal.edu.co/handle/unal/80888Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, gráficas, tablasIntroducción: La epilepsia es una patología importante con consecuencias neurobiológicas, cognitivas, psicológicas y sociales, entre un 10-20% de los pacientes serán refractarios a manejo farmacológico, el pobre control de crisis epilépticas tiene un impacto negativo para el individuo y su familia, generando un compromiso en la calidad de vida. Dentro de las opciones de tratamiento se encuentra la cirugía de epilepsia, que busca impactar de forma integral en los pacientes. Objetivo: Determinar el impacto en calidad de vida de los niños y adolescentes con epilepsia refractaria que han sido tratados con cirugía de epilepsia, usando como herramienta de medición la escala ECANIVAE-LICCE. Metodología: Estudio observacional, se revisaron las historias clínicas de los pacientes pediátricos ingresados al programa de cirugía de epilepsia entre enero de 2017 y diciembre de 2019, se evaluó la escala ECANIVAE-LICCE pre y postquirúrgica. Resultados: Se analizaron 24 pacientes, 91,7% con un síndrome epiléptico focal, 100% con alteraciones en neuroimagenes, en promedio requirieron el uso de 3 medicamentos de forma simultánea, el 37,5% recibieron intervenciones no farmacológicas, la mediana de edad al momento de la cirugía fue de 10.5 años, 54,2% de los pacientes quedaron libres de crisis posterior a cirugía. Continuaban con igual puntuación en la escala de calidad de vida el 54,2%, estaban en peor condición el 25% y con una mejor condición que previo a la intervención el 20,8%. Conclusiones: Los pacientes evaluados lograron disminución en la frecuencia de crisis posterior a la intervención quirúrgica, sin embargo esto no influyó en la modificación de la escala de calidad vida. (Texto tomado de la fuente).Introduction: Epilepsy is an important pathology with neurobiological, cognitive, psychological and social consequences, between 10-20% of patients will be refractory to pharmacological management, poor control of epileptic seizures has a negative impact on the individual and their family, generating a commitment to quality of life. Among the treatment options is epilepsy surgery, which seeks to have a comprehensive impact on patients. Objective: To determine the impact on the quality of life of children and adolescents with refractory epilepsy who have been treated with epilepsy surgery, using the ECANIVAE-LICCE scale as a measurement tool. Methodology: Observational study, the medical records of pediatric patients admitted to the epilepsy surgery program between January 2017 and December 2019 were reviewed, the pre and post-surgical ECANIVAE-LICCE scale was evaluated. Results: 24 patients were analyzed, 91.7% with a focal epileptic syndrome, 100% with neuroimaging alterations, on average they required the use of 3 drugs simultaneously, 37.5% received non-pharmacological interventions, the median age at the time of surgery, it was 10.5 years, 54.2% of the patients were seizure-free after surgery. 54.2% continued with the same score on the quality of life scale, 25% were in a worse condition and 20.8% were in a better condition than before the intervention. Conclusions: The evaluated patients achieved a decrease in the frequency of seizures after the surgical intervention, however it did not influence the modification of the quality of life scale.Incluye anexosEspecialidades MédicasEspecialista en Neuropediatría-Tipo de estudio Estudio observacional con componente descriptivo y analítico de tipo corte transversal. -Población de estudio Niños y adolescentes con epilepsia refractaria que fueron valorados en el programa de cirugía de epilepsia de UNIEPILEPSIAS, durante el periodo de enero de 2017 a diciembre de 2019. -Criterios de inclusión • Edad entre 0 y 17 años y 11 meses. • Diagnóstico de epilepsia refractaria. • Ingresados en el programa de cirugía de epilepsia durante el periodo de enero de 2017 a diciembre de 2019. • Que hayan sido tratados con cualquier tipo de procedimiento quirúrgico para el tratamiento de la epilepsia. • Que hayan diligenciado la escala de calidad de vida ECAVINAE-LICCE al ingreso y a los 6 meses de la intervención. -Criterios de exclusión • Niños y adolescentes que no hayan diligenciado la escala ECANIVAE-LICCE. • Que no sean candidatos a ningún tipo de manejo quirúrgico para la epilepsia. -Diseño muestral Muestra por conveniencia de niños y adolescentes que cumplieron con los criterios de inclusión y exclusión. -Instrumento utilizado para evaluación de calidad de vida Escala ECANIVAE-LICCE según grupo de edad correspondiente: - 0 a 3 años. - 4 a 10 años. - 11 a 17 años y 11 meses. -Instrumento de recolección de la información Diseño de instrumento de recolección de datos (Anexo A). - Aspectos operativos - Identificación de pacientes: Se buscará pacientes con diagnóstico de epilepsia refractaria ingresados al programa de cirugía de epilepsia del centro UNIEPILEPSIAS, basados en los registros de la institución y las historias clínicas de los pacientes - Los datos sociodemográficos, clínicos, y los resultados de la aplicación de la escala ECAVINAE-LICCE (Anexo D) serán obtenidos a partir de la historia clínica institucional. - Los datos que no puedan recolectarse de la historia clínica, serán diligenciados a través de llamada telefónica al paciente y/o acudiente del paciente -Variables del estudio Ver tabla de descripción de variables en el Anexo C. -Programa a utilizar para análisis de datos Se digitarán los datos en una hoja de cálculo de Microsoft Excel, cuya tabulación corresponderá a lo establecido en la definición para cada variable estudiada definido en el instrumento de recolección de datos, de forma posterior se realizará un análisis estadístico con el programa Statistical Package for the Social Sciences (SPSS). -Plan de análisis de la información Se realizará un análisis univariado de las variables cualitativas en términos de frecuencias absolutas y relativas, Se determinará la distribución de estas variables como normal o no normal con el uso de la prueba estadística de normalidad de Shapiro-Wilks, con lo cual se podrá definir para las variables de distribución no normal la mediana y los percentiles, y para las variables de distribución normal se definirá la media y sus desviaciones estándar. Para el análisis bivariado de las variables cuantitativas se buscará su asociación tomando como significativa un valor de p <0.05%, la medida de asociación será el Odds ratio (OR), sobre el que se estimarán sus respectivos intervalos de confianza (IC) a 95%. Para estimar las asociaciones con variables cuantitativas se utilizará la prueba de Mann-Whitney U. Recursos -Recurso humano Para la investigación se requirió: • Estudiante investigador • Tutor • Epidemiólogo -Recursos físicos Para la realización del estudio se usaron los siguientes componentes físicos: • Computador con acceso a internet • Papelería (hojas y lapiceros) • Acceso al archivo de historias clínicas en físicoLínea de investigación en epilepsiaxvii, 61 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Especialidad en NeuropediatríaDepartamento de PediatríaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y saludSalud del NiñoEpilepsia/cirugíaComodidad del PacienteChild HealthEpilepsy/surgeryPatient ComfortEpilepsiaPediatríaCirugía de epilepsiaCalidad de vidaEpilepsyPediatricsEpilepsy surgeryQuality of lifeCaracterización de pacientes pediátricos antes y después de la realización de cirugía de epilepsia: un enfoque en calidad de vidaCharacterization of pediatric patients before and after epilepsy surgery: a focus on quality of lifeTrabajo de grado - Especialidad Médicainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMBiremeFisher RS, Beghi E, Berg A, Carpio A, Forsgren L, Hesdorffer DC, et al. 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Epilepsy Res Treat. 2014 Apr;2014(1):1–9.Público generalORIGINAL1094916048.2022.pdf1094916048.2022.pdfTesis de Especialidad en Neuropediatríaapplication/pdf459181https://repositorio.unal.edu.co/bitstream/unal/80888/3/1094916048.2022.pdfbb5ea1246f991aa19ab5748442a7935dMD53LICENSElicense.txtlicense.txttext/plain; charset=utf-84074https://repositorio.unal.edu.co/bitstream/unal/80888/4/license.txt8153f7789df02f0a4c9e079953658ab2MD54THUMBNAIL1094916048.2022.pdf.jpg1094916048.2022.pdf.jpgGenerated Thumbnailimage/jpeg5379https://repositorio.unal.edu.co/bitstream/unal/80888/5/1094916048.2022.pdf.jpg54a4533a717a09913d89ff68b67e5886MD55unal/80888oai:repositorio.unal.edu.co:unal/808882023-07-31 23:04:47.084Repositorio Institucional Universidad Nacional de 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