Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field

The blood flow of a wide neck saccular cerebral aneurysm is modeled using numerical methods, before and after positioning a diverter flow or stent as endovascular treatment. Blood, as a magnetic fluid, is modeled computationally under the influence of different external magnetic fields. For this, a...

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Autores:
Cardona Taborda, Melisa
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/76458
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/76458
http://bdigital.unal.edu.co/72872/
Palabra clave:
Wide neck aneurysm
Endothelization
Magnetic field fishing
Computational Fluid Dynamics
Magnetohydrodynamics.
Dinámica de fluidos computacional
Magneto-hidrodinámica.
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
id UNACIONAL2_4add8376062c87529c81d686ca5a8b41
oai_identifier_str oai:repositorio.unal.edu.co:unal/76458
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field
title Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field
spellingShingle Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field
Wide neck aneurysm
Endothelization
Magnetic field fishing
Computational Fluid Dynamics
Magnetohydrodynamics.
Dinámica de fluidos computacional
Magneto-hidrodinámica.
title_short Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field
title_full Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field
title_fullStr Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field
title_full_unstemmed Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field
title_sort Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field
dc.creator.fl_str_mv Cardona Taborda, Melisa
dc.contributor.author.spa.fl_str_mv Cardona Taborda, Melisa
dc.contributor.spa.fl_str_mv Ramírez Patiño, Juan Fernando
dc.subject.proposal.spa.fl_str_mv Wide neck aneurysm
Endothelization
Magnetic field fishing
Computational Fluid Dynamics
Magnetohydrodynamics.
Dinámica de fluidos computacional
Magneto-hidrodinámica.
topic Wide neck aneurysm
Endothelization
Magnetic field fishing
Computational Fluid Dynamics
Magnetohydrodynamics.
Dinámica de fluidos computacional
Magneto-hidrodinámica.
description The blood flow of a wide neck saccular cerebral aneurysm is modeled using numerical methods, before and after positioning a diverter flow or stent as endovascular treatment. Blood, as a magnetic fluid, is modeled computationally under the influence of different external magnetic fields. For this, a list of factors that can be varied in the external magnetic field configuration and, in turn, can affect the velocity field of the blood flow of the stented aneurysm is selected. By varying the amplitude, direction and frequency of the magnetic field, it is concluded that the amplitude has an incidence on blood velocity and shear stress in the regions where the aneurysm starts and in the stent spires. After studying the changes in blood flow, a suspension of idealized endothelial cells is computationally injected, the trajectory is modeled and the cells that are trapped on the stent spires are quantified. With this, it is possible to understand the changes in the flow conditions of the cells and to examine whether, when the blood flow is subjected to an external magnetic field, it is possible to trap endothelial cells in the region of the stent. Trapped cells finally would promote complete occlusion of the neck of the aneurysm through the stimulation of tissue growth called endothelialization.
publishDate 2019
dc.date.issued.spa.fl_str_mv 2019-06-27
dc.date.accessioned.spa.fl_str_mv 2020-03-30T06:20:20Z
dc.date.available.spa.fl_str_mv 2020-03-30T06:20:20Z
dc.type.spa.fl_str_mv Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/TM
status_str acceptedVersion
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/76458
dc.identifier.eprints.spa.fl_str_mv http://bdigital.unal.edu.co/72872/
url https://repositorio.unal.edu.co/handle/unal/76458
http://bdigital.unal.edu.co/72872/
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.ispartof.spa.fl_str_mv Universidad Nacional de Colombia Sede Medellín Facultad de Minas Escuela de Ingeniería Eléctrica y Mecánica
Escuela de Ingeniería Eléctrica y Mecánica
dc.relation.haspart.spa.fl_str_mv 62 Ingeniería y operaciones afines / Engineering
dc.relation.references.spa.fl_str_mv Cardona Taborda, Melisa (2019) Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field. Maestría thesis, Universidad Nacional de Colombia - Sede Medellín.
dc.rights.spa.fl_str_mv Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.spa.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
Derechos reservados - Universidad Nacional de Colombia
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
institution Universidad Nacional de Colombia
bitstream.url.fl_str_mv https://repositorio.unal.edu.co/bitstream/unal/76458/1/1152445568.2019.pdf
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bitstream.checksum.fl_str_mv 809fb5fb7f27b3a52fbcf316b1628906
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bitstream.checksumAlgorithm.fl_str_mv MD5
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repository.name.fl_str_mv Repositorio Institucional Universidad Nacional de Colombia
repository.mail.fl_str_mv repositorio_nal@unal.edu.co
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spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Ramírez Patiño, Juan FernandoCardona Taborda, Melisa695394ac-f60f-402a-bf0b-09a5416142773002020-03-30T06:20:20Z2020-03-30T06:20:20Z2019-06-27https://repositorio.unal.edu.co/handle/unal/76458http://bdigital.unal.edu.co/72872/The blood flow of a wide neck saccular cerebral aneurysm is modeled using numerical methods, before and after positioning a diverter flow or stent as endovascular treatment. Blood, as a magnetic fluid, is modeled computationally under the influence of different external magnetic fields. For this, a list of factors that can be varied in the external magnetic field configuration and, in turn, can affect the velocity field of the blood flow of the stented aneurysm is selected. By varying the amplitude, direction and frequency of the magnetic field, it is concluded that the amplitude has an incidence on blood velocity and shear stress in the regions where the aneurysm starts and in the stent spires. After studying the changes in blood flow, a suspension of idealized endothelial cells is computationally injected, the trajectory is modeled and the cells that are trapped on the stent spires are quantified. With this, it is possible to understand the changes in the flow conditions of the cells and to examine whether, when the blood flow is subjected to an external magnetic field, it is possible to trap endothelial cells in the region of the stent. Trapped cells finally would promote complete occlusion of the neck of the aneurysm through the stimulation of tissue growth called endothelialization.Resumen: El flujo de sangre de un aneurisma cerebral, sacular de cuello amplio, es modelado usando métodos numéricos, antes y después de posicionar un diversor de flujo o stent como tratamiento endovascular. La sangre, como fluido magnético, es modelada computacionalmente bajo la influencia de diferentes campos magnéticos externos. Para esto, se selecciona una lista de factores que pueden ser variados en la configuración del campo magnético externo y a su vez pueden afectar el campo de velocidades del flujo de sangre del aneurisma con stent. Al variar la magnitud, dirección y frecuencia del campo magnético, se concluye que la magnitud tiene incidencia en la velocidad de la sangre y en el esfuerzo cortante en las regiones donde se inicia el aneurisma y en las espiras del stent. Después de estudiar los cambios en el flujo de sangre, se inyectan computacionalmente una suspensión de células endoteliales idealizadas, se modela su trayectoria y se cuantifican las células que son atrapadas por las espiras del stent en la región del cuello del aneurisma. Con esto, es posible comprender los cambios en las condiciones de flujo de las células y examinar si cuando el flujo de sangre es sometido a un campo magnético externo, es posible atrapar células endoteliales en la región del stent para finalmente promover la oclusión completa del cuello del aneurisma a través del estímulo del crecimiento de tejido llamado endotelizaciónMaestríaapplication/pdfspaUniversidad Nacional de Colombia Sede Medellín Facultad de Minas Escuela de Ingeniería Eléctrica y MecánicaEscuela de Ingeniería Eléctrica y Mecánica62 Ingeniería y operaciones afines / EngineeringCardona Taborda, Melisa (2019) Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic field. Maestría thesis, Universidad Nacional de Colombia - Sede Medellín.Blood flow computational characterization inside an idealized saccular aneurysm in presence of magnetic fieldTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMWide neck aneurysmEndothelizationMagnetic field fishingComputational Fluid DynamicsMagnetohydrodynamics.Dinámica de fluidos computacionalMagneto-hidrodinámica.ORIGINAL1152445568.2019.pdfTesis de Maestría en Ingeniería Mecánicaapplication/pdf3382964https://repositorio.unal.edu.co/bitstream/unal/76458/1/1152445568.2019.pdf809fb5fb7f27b3a52fbcf316b1628906MD51THUMBNAIL1152445568.2019.pdf.jpg1152445568.2019.pdf.jpgGenerated Thumbnailimage/jpeg5132https://repositorio.unal.edu.co/bitstream/unal/76458/2/1152445568.2019.pdf.jpg02fcd6341c20f9c99fd2c6d3e4ea332fMD52unal/76458oai:repositorio.unal.edu.co:unal/764582023-08-04 10:03:11.266Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co