Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos

ilustraciones, gráficas, tablas

Autores:: Gómez Tovar, Luz Omaira

Tipo de recurso:: Doctoral thesis

Fecha de publicación:: 2022

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: spa

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network_acronym_str	UNACIONAL2
network_name_str	Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv	Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos
dc.title.translated.eng.fl_str_mv	Nursing intervention to reduce incidence and duration of delirium in patients in intensive care
title	Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos
spellingShingle	Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos 610 - Medicina y salud::614 - Medicina Forense; incidencia de lesiones, heridas, enfermedades; medicina preventiva pública Trastornos Mentales/enfermería Delirio/enfermería Mental Disorders/nursing Delirium/nursing Delirium Enfermería de Cuidados Críticos Investigación en Enfermería Atención de Enfermería Teoría de enfermería Ensayo Clínico Critical Care Nursing Nursing Research Nursing Care Nursing Theory Clinical Trial Servicio de enfermería Nursing
title_short	Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos
title_full	Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos
title_fullStr	Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos
title_full_unstemmed	Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos
title_sort	Intervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivos
dc.creator.fl_str_mv	Gómez Tovar, Luz Omaira
dc.contributor.advisor.spa.fl_str_mv	Henao Castaño, Ángela María
dc.contributor.author.spa.fl_str_mv	Gómez Tovar, Luz Omaira
dc.contributor.researchgroup.spa.fl_str_mv	Urgencias y Cuidado Crítico
dc.contributor.orcid.spa.fl_str_mv	Gómez Tovar, Luz Omaira [0000-0003-1054-8697]
dc.contributor.cvlac.spa.fl_str_mv	Gómez Tovar, Luz Omaira [0001509431]
dc.contributor.scopus.spa.fl_str_mv	Gómez Tovar, Luz Omaira [57112723700]
dc.contributor.researchgate.spa.fl_str_mv	Gómez Tovar, Luz Omaira [Luz-Gomez-Tovar-2]
dc.contributor.googlescholar.spa.fl_str_mv	Gómez Tovar, Luz Omaira [fJIhbO8AAAAJ&hl]
dc.subject.ddc.spa.fl_str_mv	610 - Medicina y salud::614 - Medicina Forense; incidencia de lesiones, heridas, enfermedades; medicina preventiva pública
topic	610 - Medicina y salud::614 - Medicina Forense; incidencia de lesiones, heridas, enfermedades; medicina preventiva pública Trastornos Mentales/enfermería Delirio/enfermería Mental Disorders/nursing Delirium/nursing Delirium Enfermería de Cuidados Críticos Investigación en Enfermería Atención de Enfermería Teoría de enfermería Ensayo Clínico Critical Care Nursing Nursing Research Nursing Care Nursing Theory Clinical Trial Servicio de enfermería Nursing
dc.subject.decs.spa.fl_str_mv	Trastornos Mentales/enfermería Delirio/enfermería
dc.subject.decs.eng.fl_str_mv	Mental Disorders/nursing Delirium/nursing
dc.subject.proposal.spa.fl_str_mv	Delirium Enfermería de Cuidados Críticos Investigación en Enfermería Atención de Enfermería Teoría de enfermería Ensayo Clínico
dc.subject.proposal.eng.fl_str_mv	Critical Care Nursing Nursing Research Nursing Care Nursing Theory Clinical Trial
dc.subject.unesco.none.fl_str_mv	Servicio de enfermería Nursing
description	ilustraciones, gráficas, tablas
publishDate	2022
dc.date.issued.none.fl_str_mv	2022-11-29
dc.date.accessioned.none.fl_str_mv	2023-01-20T17:35:27Z
dc.date.available.none.fl_str_mv	2023-01-20T17:35:27Z
dc.type.spa.fl_str_mv	Trabajo de grado - Doctorado
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/doctoralThesis
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/acceptedVersion
dc.type.coar.spa.fl_str_mv	http://purl.org/coar/resource_type/c_db06
dc.type.content.spa.fl_str_mv	Text
dc.type.redcol.spa.fl_str_mv	http://purl.org/redcol/resource_type/TD
format	http://purl.org/coar/resource_type/c_db06
status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/83048
dc.identifier.instname.spa.fl_str_mv	Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv	https://repositorio.unal.edu.co/
url	https://repositorio.unal.edu.co/handle/unal/83048 https://repositorio.unal.edu.co/
identifier_str_mv	Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv	spa
language	spa
dc.relation.indexed.spa.fl_str_mv	Bireme
dc.relation.references.spa.fl_str_mv	American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders [Internet]. 5a Edition. Diagnostic and Statistical Manual of Mental Disorders. Washington; 2013. 991 p. Available from: https://cdn.website-editor.net/30f11123991548a0af708722d458e476/files/uploaded/DSM%2520V.pdf Burry LD, Williamson DR, Mehta S, Perreault MM, Mantas I, Mallick R, et al. Delirium and exposure to psychoactive medications in critically ill adults: A multi-centre observational study. J Crit Care [Internet]. 2017;42:268–74. Available from: https://doi.org/10.1016/j.jcrc.2017.08.003 Mitchell ML, Keane S, Rattrayf JE, Hullg AM, Davisd C, Murfieldb JE, et al. A family intervention to reduce delirium in hospitalised ICU patients: A feasibility randomised controlled trial. Intensive Crit Care Nurs [Internet]. 2017;40(9):77–84. Available from: http://doi.org/10.1016/j.iccn.2017.01.001 Lee A, Mu L, Chiu H, Gin T, Underwood MJ, Cth F, et al. Effect of motor subtypes of delirium in the intensive care unit on fast-track failure after cardiac surgery. J Thorac Cardiovasc Surg [Internet]. 2018;155(1):268-275.e1. Available from: https://doi.org/10.1016/j.jtcvs.2017.08.139 Tian J, Chen X, Liu D. Prediction of length of hospital stay and mortality in patients with delirium: A prospective cohort analysis of 200 icu patients. J Biol Regul Homeost Agents [Internet]. 2018;32(3):681–5. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29921399 Henao Castaño ÁM, Amaya Rey MCDP. Estudio piloto: Monitoreo del delirium en pacientes adultos despiertos con ventilación mecánica en la Unidad de Cuidado Intensivo. Conoc en Enfermería. 2017;1(1):4–12 Zamoscik K, Godbold R, Freeman P. Intensive care nurses’ experiences and perceptions of delirium and delirium care. Intensive Crit Care Nurs [Internet]. 2017;40:94–100. Available from: http://dx.doi.org/10.1016/j.iccn.2017.01.003 Barr J, Fraser G, Puntillo K, Wesley E, Gélinas C, Dasta J, et al. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit: Executive summary. Am J Heal Pharm [Internet]. 2013;70:53–8. Available from: http://www.ajhp.org/content/70/1/53.long?sso-checked=true Devlin JW, Skrobik Y, Gélinas C, Needham DM, Slooter AJC, Pandharipande PP, et al. Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Crit Care Med [Internet]. 2018;46(9):825–73. Available from: https://doi.org/10.1097/CCM.0000000000003299 Baron R, Binder A, Biniek R, Braune S, Buerkle H, Dall P, et al. Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015). Ger Med Sci [Internet]. 2015;13(12):42. Available from: https://doi.org/10.3205/000223 Von Rueden KT, Wallizer B, Thurman P, McQuillan K, Andrews T, Merenda J, et al. Delirium in Trauma Patients: Prevalence and Predictors. Crit Care Nurse [Internet]. 2017;37(1):40–9. Available from: //doi.org/10.4037/ccn2017373 40 Donovan AL, Matthew Aldrich J, Kendall Gross A, Barchas DM, Thornton KC, Schell-Chaple HM, et al. Interprofessional care and teamwork in the ICU. Crit Care Med. 2018;46(6):980–90. Karabulut N, Aktas YY. Nursing Management of Delirium in the Postanesthesia Care Unit and Intensive Care Unit. J PeriAnesthesia Nurs [Internet]. 2016;31(5):397–405. Available from: http://doi.org/10.1016/j.jopan.2014.10.006 Gómez Tovar LO, Henao Castaño AM. Analysis of Delirium From the Dynamic Symptoms Model: A Literature Review. Crit Care Nurs Q. 2020;43(3):312–36. Sidani S, Jo Braden C. Design, Evaluation, and Translation of Nursing Interventions. Design, Evaluation, and Translation of Nursing Interventions. 2013. 1–304 p. Fawcett J. Analysis and Evaluation of Contemporary Nursing Knowledge: Nursing Models and Theories. Philadelphia; 1992. 812 p. Pinho C, Cruz S, Santos A, Abelha FJ. Postoperative delirium: age and low functional reserve as independent risk factors. J Clin Anesth [Internet]. 2016;33:507–13. Available from: http://dx.doi.org/10.1016/j.jclinane.2015.09.002 Zhang W, Hu W, Shen M, Ye X, Huang Y, Sun Y. Profiles of delirium and the clinical outcomes of patients who underwent coronary artery bypass grafting : a prospective study from. J Clin Nurs [Internet]. 2016;25:631–41. Available from: https://doi.org/10.1111/jocn.13089 Smulter N, Claesson H, Gustafson Y, Olofsson B. Delirium after cardiac surgery: incidence and risk factors†. Interact Cardiovasc Thorac Surg. 2013;17(July):790–6. Svenningsen H, Tønnesen EK, Videbech P, Frydenberg M, Christensen D. Intensive care delirium – effect on memories and health-related quality of life – a follow-up study. J Clin Nurs [Internet]. 2013;23:634–44. Available from: https://doi.org/10.1111/jocn.12250 Patel J, Baldwin J, Bunting P, Laha S. The effect of a multicomponent multidisciplinary bundle of interventions on sleep and delirium in medical and surgical intensive care patients. Anaesthesia [Internet]. 2014;69:540–9. Available from: https://doi.org/10.1111/anae.12638 Park SA, Tomimaru Y, Shibata A, Miyagawa S, Noguchi K, Dono K. Incidence and Risk Factors for Postoperative Delirium in Patients After Hepatectomy. World J Surg [Internet]. 2017;41(11):2847–53. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28608014 Dotti S, Bigalli D, Pouso M. Delirium in the postoperative period of cardiac surgery. Rev Uruguaya Cardiol [Internet]. 2017;32(2):150–7. Available from: http://www.scielo.edu.uy/pdf/ruc/v32n2/1688-0420-ruc-32-02-00150.pdf Mesa P, Previgliano IJ, Altez S, Favretto S, Orellano M, Lecor C, et al. Delirium in a Latin American intensive care unit. A prospective cohort study of mechanically ventilated patients. Rev Bras Ter Intensiva [Internet]. 2017;29(3):337–45. Available from: https://doi.org/10.5935/0103-507x.20170058 Shankar P, Mueller A, Packiasabapathy S, Gasangwa D, Patxot M, O’Gara B, et al. Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): Protocol for a prospective randomized controlled trial. Trials [Internet]. 2018;19(1):1–8. Available from: //doi.org/10.1186/s13063-018-2718-0 Jaiswal SJ, McCarthy TJ, Wineinger NE, Kang DY, Song J, Garcia S, et al. Melatonin and Sleep in Preventing Hospitalized Delirium: A Randomized Clinical Trial. Am J Med [Internet]. 2018;131(9):1110-1117.e4. Available from: https://doi.org/10.1016/j.amjmed.2018.04.009 Sosa FA, Roberti J, Franco MT, Kleinert MM, Patrón AR, Osatnik J. Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina. Rev Bras Ter Intensiva [Internet]. 2018;30(1):50–6. Available from: 10.5935/0103-507X.20180010 Stewart C, Bench S. Evaluating the implementation of confusion assessment method-intensive care unit using a quality improvement approach. Br Assoc Crit Care Nurses [Internet]. 2018;23(4):172–8. Available from: 10.1111/nicc.12354 Pan Y, Jiang Z, Wang L, Yuan C, Wng L, Zhang J, et al. Influence of physical restraint on delirium of adult patients in ICU: A nested case – control study. J Clin Nurs. 2018;27(February):1950–7. Barman A, Pradhan D, Bhattacharyya P, Dey S, Bhattacharjee A. Diagnostic accuracy of delirium assessment methods in critical care patients. J Crit Care [Internet]. 2018;44:82–6. Available from: https://doi.org/10.1016/j.jcrc.2017.10.013 Ingalls MNK, Mc U, Armstrong CB, Mc U, Hester CM, Nc U, et al. The Fog of War: Delirium Prevalence in a Combat Intensive Care Unit. Mil Med [Internet]. 2016;181(3):209–12. Available from: http://doi.org/10.7205/MILMED-D-15-00064 Panitchote A, Tangvoraphonkchai K, Suebsoh N, Eanmma W, Chanthonglarng B, Tiamkao S, et al. Under-recognition of delirium in older adults by nurses in the intensive care unit setting. Aging Clin Exp Res [Internet]. 2015;27(5):735–40. Available from: https://doi.org/10.1007/s40520-015-0323-6 Carrasco M, Villarroel, Luis. Calderón J, Martínez, Gabriel. Andrade Maricarmen. Gonzále M. Riesgo de delirium durante la hospitalización en personas mayores: desarrollo y validación de un modelo de predicción clínica. Rev Med Chil [Internet]. 2014;142:826–32. Available from: //dx.doi.org/10.4067/S0034-98872014000700002 Adam BD, Holcomb R, Buser M, Mayfield B, Thomas J. Enhancing Food Safety, Product Quality, and Value-Added in Food Supply Chains Using Whole-Chain Traceability. Int Food Agribus Manag Rev. 2016;19:191–213. Lin Y, Chen J, Wang Z. Meta-Analysis of Factors Which Influence Delirium Following Cardiac Surgery. J Card Surg. 2012;27(2):481–92. Johnson K, Diana S, Todd J, Mcfarren A, Domb A, Mangram A, et al. Early recognition of delirium in trauma patients. Intensive Crit Care Nurs [Internet]. 2016;34:28–32. Available from: http://dx.doi.org/10.1016/j.iccn.2015.10.001 Henao Castaño AM. Delirium en pacientes con ventilación mecánica en la UCI: factores asociados y cuidado de enfermería [Internet]. 2013. Available from: http://www.bdigital.unal.edu.co/10551/1/539640.2013.pdf Gómez Tovar LO, Díaz Suarez L, Cortés Muñóz F. Cuidados de enfermería basados en evidencia y modelo de Betty Neuman, para controlar estresores del entorno que pueden ocasionar delirium en unidad de cuidados intensivos. Enfermería Glob. 2016;No 41:49–63. Todd OM, Gelrich L, Maclullich AM, Driessen M, Thomas C, Kreisel SH. Sleep Disruption at Home as an Independent Risk Factor for Postoperative Delirium. Am Geriatr Soc [Internet]. 2017;65(5):949–57. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28306148 Watson PL, Ceriana P, Fanfulla F. Delirium: Is sleep important? Best Pract Res Clin Anaesthesiol [Internet]. 2012;26(3):355–66. Available from: http://dx.doi.org/10.1016/j.bpa.2012.08.005 Henao Castaño ÁM, Amaya Rey MCDP. Delirium in awake patients with mechanical ventilation in intensive care unit. Rev Latinoam Bioética [Internet]. 2015;15(1):120–9. Available from: http://www.scielo.org.co/pdf/rlb/v15n1/v15n1a11.pdf Torres-Contreras CC, Páez-Esteban AN, Hinestrosa-Díaz del Castillo A, Rincón-Romero MK, Amaris-Vega A, Martínez-Patiño JP. Factores asociados con el delirium en pacientes críticos de una institución de salud de Bucaramanga, Colombia. Enferm Intensiva [Internet]. 2018;30(4):1–8. Available from: https://doi.org/10.1016/j.enfi.2018.03.002 Durán Cárdenas LD, Suárez Salamanca N, Mesa Villamizar Y. Modelo de Betty Newman aplicado a la prevención deldelirium en pacientes de la unidad de cuidados intensivos de Los Comuneros Hospital Universitario De Bucaramanga. Universidad de Santander; 2016. Hoyos Pinedo LE. Prevalencia Y Factores De Riesgo Asociados Al Desarrollo De Delirium En La Unidad De Críticos De Gestión Salud En Cartagena De Indias. Universidad de Cartagena; 2018. Restrepo D, Duque M, Montoya L, Berrouet MC, Rojas M, Lopera G, et al. Risk Factors and Hospital Mortality in Surgical and Non-surgical Patients with Delirium. Rev Colomb Psiquiatr [Internet]. 2018;47(3):148–54. Available from: http://dx.doi.org/10.1016/j.rcp.2017.03.001 Van De Pol I, Iterson M Van, Maaskant J. Intensive and Critical Care Nursing Effect of nocturnal sound reduction on the incidence of delirium in intensive care unit patients : An interrupted time series analysis. Intensive Crit Care Nurs [Internet]. 2017;41:18–25. Available from: http://dx.doi.org/10.1016/j.iccn.2017.01.008 Shehabi Y, Riker RR, Bokesch PM, Wisemandle W, Shintani A, Ely EW. Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients. Crit Care Med. 2010;38(12):2311–8. Henao Castaño AM, Amaya Rey MCDP. Nursing and patients with delirium: a literature review. Investig y Educ en enfermería [Internet]. 2014;32(1):148–56. Available from: https://aprendeenlinea.udea.edu.co/revistas/index.php/iee/article/view/18614/15969 Teoria de mediano rango hilando investigacion y practica para crear conocimiento para el nuevo milenio Lierh, Smith 1999.pdf. Mori S, Takeda JRT, Fernanda Souza Angotti Carrara CRC, Zanei SSV, Whitaker IY. Incidência e fatores relacionados ao delirium em Unidade de Terapia Intensiva. Rev Esc Enferm [Internet]. 2016;50(4):587–93. Available from: //dx.doi.org/10.1590/S0080-623420160000500007 Hickin SL, White S, Knopp-sihota J. Intensive and Critical Care Nursing Nurses ’ knowledge and perception of delirium screening and assessment in the intensive care unit : Long-term effectiveness of an education-based knowledge translation intervention. Intensive Crit Care Nurs [Internet]. 2017;41:43–9. Available from: http://dx.doi.org/10.1016/j.iccn.2017.03.010 Pollock JS, Hollenbeck RD, Wang L, Holmes B, Young MN, Peters M, et al. Delirium in survivors of Cardiac Arrest Treated with Mild Therapeutic Hypothermia. Am J Crit Care [Internet]. 2016;25(4):81–90. Available from: https://dx.doi.org/10.4037/ajcc201658 Gélinas C, Bérubé M, Chevrier A, Pun BT, Ely DEW, Skrobik Y, et al. Delirium Assessment Tools for Use in Critically Ill Adults: A Psychometric Analysis and Systematic Review. CriticalCareNurse [Internet]. 2018;38(1):38–50. Available from: https://doi.org/10.4037/ccn2018633 Marra A, Wesley E, Pandharipande PP, Patel MB. The ABCDEF Bundle in Critical Care. Crit Care Clin [Internet]. 2017;33(2):225–43. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351776/ Boehm L, Vasilevskis E, Dietrich MS, Wells N, Wesley E, Pandharinpande P, et al. Organizational Domains and Variation in Attitudes of Intensive Care Providers Toward The ABCDE Bundle. Am J Crit Care [Internet]. 2017;26(3):18–28. Available from: https://doi.org/10.4037/ajcc2017297 Faustino TN, Pedreira LC, Freitas YS de, Silva RM de O, Amaral JB do. Prevention and monitoring of delirium in older adults: an educational intervention. Rev Bras Enferm [Internet]. 2016;69(4):725–32. Available from: http://doi.org/10.1590/0034-7167.2016690416i Girard T, Pandharipande P, Wesley E. Delirium in the Intensive Care Unit. Crit Care [Internet]. 2008;12(1):1–9. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391269/ Page V, Wesley E. Delirium in Critical Care: Core Critical Care. [Internet]. First Ed. Vol. 28, Intensive & Critical Care Nursing. Cambridge; 2012. 251 p. Available from: http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=2011609350&site=ehost-live&scope=site Page VJ, Wesley E. Delirium in Critical Care. Second Edi. Cambridge UK: Cambridge University Press; 2015. 228 p. Heras La Calle G. Humanizando los cuidados intensivos, Presente y Futuro centrado en las personas [Internet]. Primera Ed. Patient experience and co-creation in health. Madrid: Distribuna; 2017. 325 p. Available from: https://healthcocreation.wordpress.com/2014/12/09/humanizando-los-cuidados-intensivos/ Cerejeira J, Firmino H, Vaz-Serra A, Mukaetova-Ladinska EB. The neuroinflammatory hypothesis of delirium. Acta Neuropathol [Internet]. 2010;119(6):737–54. Available from: https://link.springer.com/article/10.1007%2Fs00401-010-0674-1 Maldonado JR. Neuropathogenesis of delirium: Review of current etiologic theories and common pathways. Am J Geriatr Psychiatry [Internet]. 2013;21(12):1190–222. Available from: https://doi.org/10.1016/j.jagp.2013.09.005 Wesley E, Gautam S, Margolin R, Francis J, May L, Speroff T, et al. The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med. 2001;27(12):1892–900. Moon K, Lee S. International Journal of Nursing Studies The effects of a tailored intensive care unit delirium prevention protocol: A randomized controlled trial. Int J Nurs Stud [Internet]. 2015;52(9):1423–32. Available from: http://dx.doi.org/10.1016/j.ijnurstu.2015.04.021 Amaya H. La Humanización en los lineamientos del Plan Nacional de Mejoramiento de la Calidad en Salud. 2014. Brant JM, Beck S, Miaskowski C. Building dynamic models and theories to advance the science of symptom management research. J Adv Nurs [Internet]. 2010;66(1):228–40. Available from: https://doi.org/10.1111/j.1365-2648.2009.05179.x Brant J, Dudley W, Beck S, Miaskowski C. Evolution of the Dynamic Symptoms Model. Oncol Nurs Forum [Internet]. 2016;43(5):651–4. Available from: http://onf.ons.org/onf/43/5/evolution-dynamic-symptoms-model Brant JM, Dudley WN, Beck S, Miaskowski C. Evolution of the Dynamic Symptoms Model. Oncol Nurs Forum [Internet]. 2016;43(5):651–4. Available from: https://www.ncbi.nlm.nih.gov/pubmed/27541557 Gosselin TK, Beck S, Abbott DH, Grambow SC. The Symptom Experience in Rectal Cancer Survivors. J Pain Symptom Manage [Internet]. 2016;52(5):709–18. Available from: https://doi.org/10.1016/j.jpainsymman.2016.05.027 Albrecht TA. Physiologic and Psychological Symptoms Experienced by Adults With Acute Leukemia: An Integrative Literature Review. Oncol Nurs Forum [Internet]. 2014;41(3):286–95. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368444/ Matzka M, Mayer H, Köck-Hódi S, Moses-Passini C, Dubey C, Jahn P, et al. Relationship between resilience, psychological distress and physical activity in cancer patients: A cross-sectional observation study. PLoS One [Internet]. 2016;11(4):1–13. Available from: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0154496 Rowley-Conwy G. Intensive and Critical Care Nursing Barriers to delirium assessment in the intensive care unit: A literature review. Intensive Crit Care Nurs [Internet]. 2018;44:99–104. Available from: https://doi.org/10.1016/j.iccn.2017.09.001 González-Robledo G, León J, Buitrago AF, Carvajalino S, Abril D, González V, et al. Cuidado paliativo en falla cardiaca. Rev Colomb Cardiol [Internet]. 2017;24(3):286–96. Available from: http://dx.doi.org/10.1016/j.rccar.2016.10.049 Lara BA, Cataldo A, Castro R, Aguilera PR, Ruiz C, Andresen M. Medicina de urgencia y unidades de cuidados intensivos: Una alianza necesaria en busca de la mejoría de la atención de pacientes críticos TT - The impact of a better coordination between emergency and intensive care units in the care of critically ill pa. Rev Med Chil [Internet]. 2016;144:917–24. Available from: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000700014&lang=pt Newman MA, Smith MC, Pharris MD, Jones D. The Focus of the Discipline. Revisited. Adv Nurs Sci. 2008;31(1):16–27. Wesley Ely E. The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families. Crit Care Med [Internet]. 2017;45(2):321–30. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830123/ Velasco Bueno JM, Heras La Calle G, Ortega Guerrero Á, Gómez Tello V. Manual de buenas prácticas de Humanización en las Unidades de Cuidados Intensivos [Internet]. Madrid; 2017. Available from: http://humanizandoloscuidadosintensivos.com/es/buenas-practicas/ Balas MC, Vasilevskis EE, Burke WJ, Boehm L, Pun BT, Olsen KM, et al. Critical Care Nurses’ Role in Implementing the “ABCDE Bundle” Into Practice. Crit Care Nurse [Internet]. 2012;32(2):35–47. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375171/ Smith MC. Regenerating Nursing’s Disciplinary Perspective. Adv Nurs Sci. 2019;42(1):3–16. Trogrlic Z, Jagt M Van Der, Bakker J, Balas MC, Ely EW, Voort PHJ Van Der, et al. A systematic review of implementation strategies for assessment, prevention, and management of ICU delirium and their effect on clinical outcomes. Crit Care [Internet]. 2015;19(157):1–17. Available from: 10.1186/s13054-015-0886-9 Balas MC, Devlin JW, Verceles AC, Morris P, Wesley Ely E, Cartin-Ceba R, et al. Adapting the ABCDEF Bundle to Meet the Needs of Patients Requiring Prolonged Mechanical Ventilation in the Long-Term Acute Care Hospital Setting: Historical Perspectives and Practical Implications. Tennessee Semin Respir Crit Care Med [Internet]. 2016;37:119–35. Available from: 10.1055/s-0035-1570361 Luetz A, Weiss B, Boettcher S, Burmeister J, Wernecke KD, Spies C. Routine delirium monitoring is independently associated with a reduction of hospital mortality in critically ill surgical patients: A prospective, observational cohort study. J Crit Care [Internet]. 2016;35:168–73. Available from: http://dx.doi.org/10.1016/j.jcrc.2016.05.028 Boehm BLM, Dietrich MS, Vasilevskis EE, Wells N, Pandharipande P, Wesley E, et al. Perceptions of Workload Burden and Adherence to ABCDE Bundle Among intensive Care Providers. Am J Crit Care [Internet]. 2017;26(4):38–47. Available from: https://doi.org/10.4037/ajcc2017544 Prescott HC, Costa DK. Improving Long-Term Outcomes After Sepsis. Crit Care Clin [Internet]. 2018;34(1):175–88. Available from: https://doi.org/10.1016/j.ccc.2017.08.013 Barnes-Daly MA, Phillips G, Ely EW. Improving hospital survival and reducing brain dysfunction at Seven California Community Hospitals: Implementing PAD guidelines via the ABCDEF bundle in 6,064 patients. Crit Care Med [Internet]. 2017;45(2):171–8. Available from: https://doi.org/10.1097/CCM.0000000000002149 Mart MF, Brummel NE, Wesley E. The ABCDEF Bundle for the Respiratory Therapist. Respir Care [Internet]. 2019;64(12):1561–73. Available from: https://doi.org/10.4187/respcare.07235 Marra A, Pandharipande PP, Patel MB. Intensive Care Unit Delirium and Intensive Care Unit–Related Posttraumatic Stress Disorder. Surg Clin North Am [Internet]. 2017;97(6):1215–35. Available from: https://doi.org/10.1016/j.suc.2017.07.008 Morandi A, Piva S, Ely EW, Myatra SN, Salluh JIF, Amare D, et al. Worldwide ABCDEF (Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium monitoring/management, Early exercise/mobility, and Family Empowerment) Survey. Crit Care Med [Internet]. 2017;45(11):1111–22. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640479/ Sosnowski K, Mitchell ML, White H, Morrison L, Sutton J, Sharratt J, et al. A feasibility study of a randomised controlled trial to examine the impact of the ABCDE bundle on quality of life in ICU survivors. Pilot Feasibility Stud [Internet]. 2018;4(1):1–12. Available from: https://doi.org/10.1186/s40814-017-0224-x Brenda T. Pun, Balas MC, Barnes-Daly MA, Thompson JL, J. Aldrich M, Barr J, et al. Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. Crit Care Med [Internet]. 2019;47(1):139–48. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298815/ Girard TD. “Wake Up and Breathe” Protocol Spontaneous Awakening Trials (SATs) + Spontaneous Breathing Trials (SBTs). Lancet [Internet]. 2008;2008(371):126–34. Available from: papers2://publication/uuid/0066DE15-A7ED-470B-AF2A-E094E16E0535 Klompas M, Anderson D, Trick W, Babcock H, Kerlin MP, Li L, et al. The preventability of ventilator-associated events: The CDC Prevention Epicenters Wake Up and Breathe Collaborative. Am J Respir Crit Care Med [Internet]. 2015;191(3):292–301. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447286/ McGinn K, Miller R, Ding L, Brevard S., Simmos J., Kahn S. 200 Spontaneous Breathing and Awakening Trials Plus a Multimodal Sedation/ Agitation Protocol Decrease Vent Days and Benzodiazepine Use in the Burn ICU. J Burn Care Res [Internet]. 2018;39(1):66-. Available from: https://doi.org/10.1093/jbcr/iry006.123 Devlin JW, Pohlman AS. Everybody, every day: An “Awakening and breathing coordination, delirium monitoring/management, and early exercise/mobility” culture is feasible in your ICU. Crit Care Med [Internet]. 2014;42(5):1280–1. Available from: https://journals.lww.com/ccmjournal/Citation/2014/05000/Everybody,_Every_Day___An__Awakening_and_Breathing.30.aspx Balas MC, Weinhouse GL, Denehy L, Chanques G, Rochwerg B, Misak CJ, et al. Interpreting and Implementing the 2018 Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption Clinical Practice Guideline. Crit Care Med [Internet]. 2018;46(9):1464–70. Available from: https://doi.org/10.1097/CCM.0000000000003307 Sessler CN, Gosnell MS, Grap MJ, Brophy GM, O’Neal P V., Keane KA, et al. The Richmond Agitation-Sedation Scale: Validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med. 2002;166(10):1338–44. Rojas-Gambasica JA, Valencia-Moreno A, Nieto-Estrada VH, Méndez-Osorio P, Molano-Franco D, Jiménez-Quimbaya ÁT, et al. Validación transcultural y lingüística de la escala de sedación y agitación Richmond al español. Rev Colomb Anestesiol [Internet]. 2016;44(3):218–23. Available from: http://dx.doi.org/10.1016/j.rca.2016.04.003 Shetty RM, Bellini A, Wijayatilake DS, Hamilton MA, Jain R, Karanth S, et al. BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the intensive care unit and its impact on clinical outcomes and resource utilization. Cochrane Database Syst Rev. 2018;2018(2). Cullen E, Balas MC. Delirium monitoring and management in the acute care setting. Nurse Pract. 2017;42(12):37–42. Miranda F, Arevalo‐Rodriguez I, Díaz G, Gonzalez F, Plana MN, Zamora J, et al. Confusion Assessment Method for the intensive care unit (CAM‐ICU) for the diagnosis of delirium in adults in critical care settings. Cochrane Database Syst Rev [Internet]. 2018;(9). Available from: http://dx.doi.org/10.1002/14651858.CD013126 American Society of Anesthesiologists Task Force on Moderate Procedural Sedation and Analgesia, the American Association of Oral and Maxillofacial Surgeons, American College of Radiology, American Dental Association, American Society of Dentist Anesthesio and S of IR. Practice Guidelines for Moderate Procedural Sedation and Analgesia 2018. Anesthesiology [Internet]. 2018;128(3):437–79. Available from: https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2670190 NICE. Delirium: pre Delirium: prevention, diagnosis and ention, diagnosis and management management Clinical guideline [Internet]. 2010. Available from: https://www.nice.org.uk/guidance/cg103/resources/delirium-prevention-diagnosis-and-management-pdf-174507018181 Munro CL, Cairns P, Ji M, Calero K, Anderson WM, Liang Z. Delirium prevention in critically ill adults through an automated reorientation intervention e A pilot randomized controlled trial. Hear Lung J Acute Crit Care [Internet]. 2017;46(4):234–8. Available from: http://dx.doi.org/10.1016/j.hrtlng.2017.05.002 Rivosecchi RM, Kane-Gill SL, Svec S, Campbell S, Smithburger PL. The implementation of a nonpharmacologic protocol to prevent intensive care delirium. J Crit Care [Internet]. 2016;31(1):206–11. Available from: http://dx.doi.org/10.1016/j.jcrc.2015.09.031 Voyer P, Champoux N, Desrosiers J, Landreville P, Mccusker J, Monette J, et al. Recognizing acute delirium as part of your routine [ RADAR ]: a validation study. BioMed Cent [Internet]. 2015;14(19):1–13. Available from: https://bmcnurs.biomedcentral.com/articles/10.1186/s12912-015-0070-1 Thomas E, Smith JE, Forrester AD, Heider G, Jadotte YT, Holly C. The effectiveness of non-pharmacological multi-component interventions for the prevention of delirium in non-intensive care unit older adult hospitalized patients: a systematic review protocol. JBI Database Syst Rev Implement Reports [Internet]. 2013;11(7):361–74. Available from: https://insights.ovid.com/crossref?an=01938924-201311070-00011 Litton E, Carnegie V, Elliott R, Webb SAR. The Efficacy of Earplugs as a Sleep Hygiene Strategy for Reducing Delirium in the ICU: A Systematic Review and Meta-Analysis*. Crit Care Med [Internet]. 2016;44(5):992–9. Available from: https://doi.org/10.1097/CCM.0000000000001557 Litton E, Elliott R, Thompson K, Nicola W, Sppelt I, Webb S. Using Clinically Accessible Tools to Measure Sound Levels and Sleep Disruption in the ICU: A Prospective Multicenter Observational Study. Crit Care Med [Internet]. 2017;45(6):966–71. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28362644 Corcoran JR, Herbsman JM, Bushnik T, Van Lew S, Stolfi A, Parkin K, et al. Early Rehabilitation in the Medical and Surgical Intensive Care Units for Patients With and Without Mechanical Ventilation: An Interprofessional Performance Improvement Project. PM R [Internet]. 2017;9(2):113–9. Available from: http://dx.doi.org/10.1016/j.pmrj.2016.06.015 Page VJ, Casarin A, Ely EW, Zhao XB, McDowell C, Murphy L, et al. Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial. Lancet Respir Med [Internet]. 2017;5(9):727–37. Available from: http://dx.doi.org/10.1016/S2213-2600(17)30234-5 Zhang W, Sun Y, Liu Y, Qiu W, Ye X, Zhang G, et al. A nursing protocol targeting risk factors for reducing postoperative delirium in patients following coronary artery bypass grafting: Results of a prospective before-after study. Int J Nurs Sci [Internet]. 2017;4(2):81–7. Available from: http://dx.doi.org/10.1016/j.ijnss.2017.02.002 Freeman S, Hallett C, Mchugh G. Physical restraint: experiences, attitudes and opinions of adult intensive care unit nurses. Nurs Crit Care [Internet]. 2015;21(2):78–87. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/nicc.12197 Birge AÖ, Aydin HT. The effect of nonpharmacological training on delirium identification and intervention strategies of intensive care nurses. Intensive Crit Care Nurs [Internet]. 2017;41:33–42. Available from: https://doi.org/10.1016/j.iccn.2016.08.009 Davidson JE, Winkelman C, Gélinas C, Dermenchyan A. Pain, Agitation, and Delirium Guidelines: Nurses’ Involvement in Development and Implementation. Crit Care Nurse [Internet]. 2015;35(3):17–33. Available from: https://doi.org/10.4037/ccn2015824 White BL, Zomorodi M. Perceived and actual noise levels in critical care units. Intensive Crit Care Nurs [Internet]. 2017;38:18–23. Available from: http://dx.doi.org/10.1016/j.iccn.2016.06.004 Girard TD, Exline MC, Carson SS, Hough CL, Rock P, Gong MN, et al. Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. N Engl J Med [Internet]. 2018;379:2506–16. Available from: http://www.nejm.org/doi/10.1056/NEJMoa1808217 Reade MC, Eastwood GM, Bellomo R, Bailey M, Bersten A, Cheung B, et al. Effect of dexmedetomidine added to standard care on ventilator-free time in patients with agitated delirium a randomized clinical trial. JAMA - J Am Med Assoc [Internet]. 2016;315(14):1460–8. Available from: https://doi.org/10.1001/jama.2016.2707 Morris PE, Goad A, Thompson C, Taylor K, Harry B, Passmore L, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med. 2008;36(8):2238–43. Nydahl P, Sricharoenchai T, Chandra S, Sari F, Ma MPH, Huang M, et al. Safety of Patient Mobilization and Rehabilitation in the ICU: Systematic Review with Meta- Analysis. Am Thorac Soc. 2017;6:1–67. Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet [Internet]. 2009;373(9678):1874–82. Available from: http://dx.doi.org/10.1016/S0140-6736(09)60658-9 Vanderbilt University Medical Center. Early Mobility and Exercise [Internet]. Icu delirium. 2013. p. 1–7. Available from: http://www.icudelirium.org/earlymobility.html Mitchell ML, Kean S, Rattray JE, Hull AM, Davis C, Murfield JE, et al. A family intervention to reduce delirium in hospitalised ICU patients: A feasibility randomised controlled trial. Intensive Crit Care Nurs [Internet]. 2017;40:77–84. Available from: http://dx.doi.org/10.1016/j.iccn.2017.01.001 Davidson JE, Aslakson RA, Long AC, Puntillo KA, Kross EK, Hart J, et al. Guidelines for Family-Centered Care in the Neonatal, Pediatric, and Adult ICU. Crit Care Med [Internet]. 2017;45(1):103–28. Available from: https://insights.ovid.com/pubmed?pmid=27984278 Liput SA, Kane-Gill SL, Seybert AL, Smithburger PL. A review of the perceptions of healthcare providers and family members toward family involvement in active adult patient care in the ICU. Crit Care Med. 2016;44(6):1191–7. Garrouste-Orgeas M, Max A, Lerin T, Grégoire C, Ruckly S, Kloeckner M, et al. Impact of proactive nurse participation in ICU family conferences: A mixed-method study. Crit Care Med. 2016;44(6):1116–28. Kram SL, Dibartolo MC, Hinderer K, Jones RA. Implementation of the ABCDE Bundle to Improve Patient Outcomes in the Intensive Care Unit in a Rural Community Hospital. Dimens Crit Care Nurs [Internet]. 2015;34(5):250–8. Available from: https://doi.org/10.1097/DCC.0000000000000129 Kang J, Lee M, Ko H, Kim S, Yun S, Jeong Y, et al. Effect of nonpharmacological interventions for the prevention of delirium in the intensive care unit: A systematic review and meta-analysis. J Crit Care [Internet]. 2018;48:372–84. Available from: https://www.sciencedirect.com/science/article/pii/S0883944118310013?dgcid=rss_sd_all Martínez F, Donoso AM, Marquez C, Labarca E. Implementing a multicomponent intervention to prevent delirium among critically ill patients. Crit Care Nurse [Internet]. 2017;37(6):36–47. Available from: http://doi.org/10.4037/ccn2017531 Rosa RG, Tonietto TF, Da Silva DB, Gutierres FA, Ascoli AM, Madeira LC, et al. Effectiveness and safety of an extended icu visitation model for delirium prevention: A before and after study. Crit Care Med. 2017;45(10):1660–7. Mailhot T, Cossette S, Côté J, Bourbonnais A, Côté MC, Lamarche Y, et al. A post cardiac surgery intervention to manage delirium involving families: a randomized pilot study. Nurs Crit Care. 2017;22(4):221–8. Johnson K, Curry V, Steubing A, Diana S, Mccray A, Mcfarren A, et al. A non-pharmacologic approach to decrease restraint use. Intensive Crit Care Nurs [Internet]. 2016;34:20–7. Available from: http://dx.doi.org/10.1016/j.iccn.2015.08.004 Smith JM, Aman MN Van. Assessment of Delirium in Intensive Care Unit Patients : Educational Strategies. J Contin Edication Nurs. 2017;48(5):239–44. Fraser V, Cossette S, Mailhot T, Brisebois A. Evaluation of an Intervention With Nurses for Delirium Detection After Cardiac Surgery. Worldviews Evidence-Based Nurs. 2018;15(1):38–44. Marino J, Bucher D, Beach M, Cooper B. Implementation of an Intensive Care Unit Delirium Protocol. Dimens Crit Care Nurs. 2015;34(5):273–84. Speed G. The Impact of a Delirium Educational Intervention With Intensive Care Unit Nurses. Clin Nurse Spec. 2015;29(2):89–94. Stadtmann MP, Maercker A, Binder J, Schnepp W. Why do I to suffer? Symptom management, views, and experiences of relatives of persons with CPTSD: a grounded theory study. J Patient-Reported Outcomes [Internet]. 2018;2(1):1–11. Available from: https://doi.org/10.1186/s41687-018-0070-5 Lin Y, Docherty SL, Porter LS, Bailey DE. Symptom experience and self-management for multiple co-occurring symptoms in patients with gastric cancer: A qualitative study. Eur J Oncol Nurs [Internet]. 2020;49. Available from: https://doi.org/10.1016/j.ejon.2020.101860 Whisenant M, Wong B, Mitchell S, Beck S, Mooney K. Distinct Trajectories of Fatigue and Sleep Disturbance in Women Receiving Chemotherapy for Breast Cancer. Oncol Nurs Forum [Internet]. 2017;44(6):739–50. Available from: http://onf.ons.org/onf/44/6/distinct-trajectories-fatigue-and-sleep-disturbance-women-receiving-chemotherapy-breast Whisenant M, Wong B, Mitchell SA, Beck SL, Mooney K. Symptom Trajectories Are Associated With Co-Occurring Symptoms During Chemotherapy For Breast Cancer. J Pain Symptom Manage [Internet]. 2018; Available from: https://linkinghub.elsevier.com/retrieve/pii/S0885392418310716%0Ahttp://www.ncbi.nlm.nih.gov/pubmed/30453052 Whisenant M, Wong B, Mitchell SA, Beck SL, Mooney K. Trajectories of Depressed Mood and Anxiety during Chemotherapy for Breast Cancer. Cancer Nurs [Internet]. 2020;43(1):22–31. Available from: https://doi.org/10.1097/NCC.0000000000000670 Partington L. Researchers The presence and intensity and the related changes over time of physical symptoms in the dying phase : A prospective cohort study of residents dying in care homes [Internet]. Lancaster University; 2020. Available from: https://doi.org/10.17635/lancaster/thesis/1102 Pinzón Casas EY. Validación del Instrumento PSCAM-ICU en su versión en español [Internet]. Universidad Nacional de Colombia; 2018. Available from: https://repositorio.unal.edu.co/handle/unal/69806 Shin H. Physical and Psychological Late Effects on Health-Related Quality of Life in Long-Term Survivors of Childhood Cancer. University of North Carolina; 2017. Riegel B, Jaarsma T, Lee CS, Strömberg A. Integrating Symptoms Into the Middle-Range Theory of Self-Care of Chronic Illness. Adv Nurs Sci. 2019;42(3):206–15. White LL, Cohen MZ, Berger AM, Kupzyk KA, Bierman PJ. Self-efficacy for management of symptoms and symptom distress in adults with cancer: An integrative review. Oncol Nurs Forum [Internet]. 2019;46(1):113–28. Available from: https://doi.org/10.1188/19.ONF.113-128 Mohr C, Jensen C, Padden N, Besel JM, Brant JM. Peppermint Essential Oil for Nausea and Vomiting in Hospitalized Patients: Incorporating Holistic Patient Decision Making Into the Research Design. J Holist Nurs [Internet]. 2020;1–9. Available from: https://doi.org/10.1177/0898010120961579 Fawcett J, DeSanto Madeya S. Contemporary Nursing Knowledge. Analysis and Evaluation of Nursing Models and Theories. Third Edit. Philadelphia: F.A. Davis Company; 2013. 642 p. Monti EJ, Tingen MS. Multiple Paradigms of Nursing Science. Adv Nurs Sci [Internet]. 1999;21(4):64–80. Available from: https://doi.org/10.1097/00012272-199906000-00010 Fawcett J, Garity J. Evaluating Research for Evidence-Based Nursing Practice. Company FAD, editor. Philadelphia; 2009. 337 p. Bueno-Robles LS. Aspectos ontológicos y epistemológicos de las visiones de enfermería inmeras en el quehacer profesional. Cienc y Enfermería. 2011;XVII(1):37–43. Newman MA, Smith MC, Pharris MD, Jones D. The focus of the discipline of nursing. Adv Nurs Sci [Internet]. 2008;31(1):16–27. Available from: http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107510098&site=ehost-live Friedman LM, Furberg CD, DeMets DL. Fundamentals of Clínical Trials. 4th Editio. Journal of Chemical Information and Modeling. New York: Springer; 2010. 464 p. Lemeshow S, Hosmer DW, Klar J, Lwanga SK. Adequacy of Sample Size in Health Studies. World Health Organization. New York: John Wiley & Sons; 1999. Wesley E, Margolin R, Francis J, May L, Truman B, Dittus R, et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med. 2001;29(7):1370–9. Tobar E, Romero C, Galleguillos T, Fuentes P, Cornejo R, Lira MT, et al. Método para la evaluación de la confusión en la unidad de cuidados intensivos para el diagnóstico de delírium: adaptación cultural y validación de la versión en idioma español. Med Intensiva. 2010;34(1):4–13. Toro AC, Escobar LM, Franco JG, Díaz-Gómez JL, Muñoz JF, Molina F, et al. Versión en español del método para la evaluación de la confusión en cuidados intensivos, estudio piloto de validación. Med Intensiva. 2010;34(1):14–21. Salinas Mendez MA. Escalas para valoración del dolor en pacientes sometidos a ventilación mecáninca con sedación y analgesia: revisión integrativa [Internet]. Universidad de Sonora; 2019. Available from: http://www.repositorioinstitucional.uson.mx/handle/unison/4156 Pardo C, Muñoz T, Chamorro C, Grupo de trabajo de analgesia y sedación de la SEMICYUC. Monitorización del dolor. Recomendaciones del grupo de trabajo de analgesia y sedación de la SEMICYUC. Med Intensiva [Internet]. 2006;30(8):379–85. Available from: https://doi.org/10.1016/s0210-5691(06)74552-1 Eizaga-Rebollar R, García-Palacios MV. Escalas de valoración del dolor [Internet]. Mexico; 2015. 82 p. Available from: http://www.1aria.com/docs/sections/areaDolor/escalasValoracion/EscalasValoracionDolor.pdf Vicente Herrero MT, Delgado Bueno S, Bandrés Moyá F, Ramírez Iñiguez de la Torre MV, Capdevila García L. Valoración del dolor. Revisión Comparativa de Escalas y Cuestionarios. Rev la Soc Española del Dolor. 2018;25(4):228–36. Rivas E, Alarcón M, Gatica V, Neupayante K, Schneider MB. Escalas de valoración de dolor en pacientes críticos no comunicaticos. Enfermería Cuid Humaniz [Internet]. 2018;7:115–29. Available from: http://www.scielo.edu.uy/pdf/ech/v7n1/2393-6606-ech-7-01-57.pdf González Pérez LX. Adaptación de la escala de Campbell para la evaluación del dolor en una unidad de cuidado intensivo de la ciudad de Bogotá [Internet]. Universidad del Rosario; 2019. Available from: https://repository.urosario.edu.co/handle/10336/19810?show=full Thabane L, Mbuagbaw L, Zhang S, Samaan Z, Marcucci M, Ye C, et al. A tutorial on sensitivity analyses in clinical trials: The what, why, when and how. BMC Med Res Methodol [Internet]. 2013;13(1). Available from: https://doi.org/10.1186/1471-2288-13-92 McCoy CE. Understanding the intention-to-treat principle in randomized controlled trials. West J Emerg Med [Internet]. 2017;18(6):1075–8. Available from: https://doi.org/10.5811/westjem.2017.8.35985 Manterola C, Otzen T. Los Sesgos en Investigación Clínica. Int J Morphol [Internet]. 2015;33(3):1156–64. Available from: https://doi.org/10.4067/s0717-95022015000300056 Hernández-Avila M, Garrido F, Salazar-Martínez E. Sesgos en estudos epidemiológicos. Salud Publica Mex [Internet]. 2000;42(5):438–46. Available from: https://www.scielosp.org/article/ssm/content/raw/?resource_ssm_path=/media/assets/spm/v42n5/3995.pdf Mundial AM. Declaración de Helsinki de la AMM - Principios éticos para las Investigaciones médicas en Seres Humanos. 1964. Instituto Nacional de Salud de los Estados Unidos. Informe de Belmont [Internet]. The Belmont Report Ethical Principles and Guidelines for the Protection of Human Subjects of Research Estados Unidos de América; 1979. Available from: http://www.pcb.ub.edu/bioeticaidret/archivos/norm/InformeBelmont.pdf Consejo de Organizaciones Internacionales de las Ciencias Médicas. Pautas éticas internacionales para la investigación relacionada con la salud con seres humanos. Organización Panamericana de la Salud. 2017. 150 p. República de Colombia. Ley Estatutaria 1581 de 2012 [Internet]. Colombia; 2012. Available from: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/DE/DIJ/RESOLUCION-8430-DE-1993.PDF República de Colombia Gobierno Nacional. Ley 911 de 2004. Colombia; 2004. Gobierno Nacional de Colombia. Ley 1581 de 2012 [Internet]. Colombia: presidencia.gov.co; 2012 p. 301. Available from: https://www.funcionpublica.gov.co/eva/gestornormativo/norma.php?i=50364 República de Colombia Ministerio de Comercio Industria y Turismo. DECRETO 1377 DE 2013 [Internet]. 1377 Colombia: Ministerio de las TIC; 2013 p. 11. Available from: https://www.funcionpublica.gov.co/eva/gestornormativo/norma.php?i=53646 Gallagher E, Rogers BB, Brant JM. Cancer-Related Pain Assessment: Monitoring the effectiveness of interventions. Clin J Oncol Nursingournal Oncol Nurs [Internet]. 2015;21(3):8–13. Available from: http://doi.org/10.1188/17.CJON.S3.8-12 Gómez Tovar LO, Henao Castaño ÁM. Intervenciones y efectividad del Paquete ABCDEF en el tratamiento de delirium: revisión de alcance. Av en Enfermería [Internet]. 2021;39(3):395–414. Available from: https://doi.org/10.15446/av.enferm.v39n3.85828 Manterola C, Asenjo-Lobos C, Otzen T. Jerarquización de la evidencia. Niveles de evidencia y grados de recomendación de uso actual. Rev Chil infectología [Internet]. 2014;31(6):705–18. Available from: https://scielo.conicyt.cl/pdf/rci/v31n6/art11.pdf Roy C. Nursing Knowledge in the 21st Century Domain-Derived and Basic Science Practice-Shaped. Adv Nurs Sci [Internet]. 2018;42(1):28–42. Available from: http://doi.org/10.1097/ANS.0000000000000240 Fawcett J. Thoughts About Thinking Theoretically and Atheoretically. Essays Nurs Sci Thoughts [Internet]. 2020;33(3):272–3. Available from: https://doi.org/10.1177/0894318420920623 Chinn PL. The Discipline of Nursing: Moving Forward Boldly [Internet]. Case Western Reserve University Frances Payne Bolton School of Nursing. 2019. p. 1–31. Available from: https://nursology.net/2019-03-21-case-keynote/%0A1 Fonsmark L, Hein L, Nibroe H, Bundgaard H, De Haas I, Iversen S, et al. Danish national sedation strategy. Targeted therapy of discomfort associated with critical illness. Danish society of intensive care medicine (DSIT) and the Danish society of Anesthesiology and intensive care medicine (DASAIM). Dan Med J [Internet]. 2015;62(4):C5052. Available from: https://ugeskriftet.dk/files/scientific_article_files/2018-11/b5052.pdf Tang B, Wang XT, Chen WJ, Zhu SH, Chao YG, Zhu B, et al. Experts consensus on the management of delirium in critically ill patients. Zhonghua nei ke za zhi [Internet]. 2019;58(2):108–18. Available from: https://pubmed.ncbi.nlm.nih.gov/30704197/ Celis-Rodríguez E, Díaz Cortés JC, Cárdenas Bolívar YR, Carrizosa González JA, Pinilla DI, Ferrer Záccaro LE, et al. Guías de práctica clínica basadas en la evidencia para el manejo de la sedoanalgesia y delirium en el paciente adulto críticamente enfermo. Med Intensiva [Internet]. 2020;44(3):171–84. Available from: https://doi.org/10.1016/j.medin.2019.07.013 Vincent JL, Shehabi Y, Walsh TS, Pandharipande PP, Ball JA, Spronk P, et al. Comfort and patient-centred care without excessive sedation: the eCASH concept. Intensive Care Med [Internet]. 2016;42(6):962–71. Available from: https://doi.org/10.1007/s00134-016-4297-4 Guo Y, Sun L, Li L, Jia P, Zhang J, Jiang H, et al. Impact of multicomponent, nonpharmacologic interventions on perioperative cortisol and melatonin levels and postoperative delirium in elderly oral cancer patients. Arch Gerontol Geriatr. 2016;62:112–7. Álvarez EA, Garrido MA, Tobar EA, Prieto SA, Vergara SO, Briceño CD, et al. Occupational therapy for delirium management in elderly patients without mechanical ventilation in an intensive care unit: A pilot randomized clinical trial. J Crit Care [Internet]. 2017;37:85–90. Available from: http://dx.doi.org/10.1016/j.jcrc.2016.09.002 Rood PJT, Zegers M, Ramnarain D, Koopmans M, Klarenbeek T, Ewalds E, et al. The Impact of Nursing Delirium Preventive Interventions in the ICU A Multicenter Cluster-randomized Controlled Clinical Trial. Am J Respir Crit Care Med [Internet]. 2021;204(6):682–91. Available from: https://doi.org/10.1164/rccm.202101-0082OC Torres Contreras CC, Páez Esteban AN, Duran Parra M, Romero Rincón MK, Giordani da Silva C, Duarte Buitrago NP. Programa de enfermería multicomponente para prevención del delirium en pacientes críticamente enfermos : ensayo clínico aleatorizado. Rev Gaúcha Enferm [Internet]. 2021;42:e20200278. Available from: https://doi.org/10.1590/1983-1447.2021.20200278 Truman B, Balas MC, Barnes-Daly MA, Thompson JL, Aldrich JM, Barr J, et al. Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. Crit Care Med [Internet]. 2019;47(1):3–14. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298815/
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dc.rights.license.spa.fl_str_mv	Atribución-NoComercial-SinDerivadas 4.0 Internacional
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dc.publisher.spa.fl_str_mv	Universisad Nacional de Colombia
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dc.publisher.faculty.spa.fl_str_mv	Facultad de Enfermería
dc.publisher.place.spa.fl_str_mv	Bogotá, Colombia
dc.publisher.branch.spa.fl_str_mv	Universidad Nacional de Colombia - Sede Bogotá
institution	Universidad Nacional de Colombia
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spelling	Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Henao Castaño, Ángela María60d6be3047a6e117bf669f77a6b73994Gómez Tovar, Luz Omaira52c9e336654bc23fe5ee7b7345b8ffa4600Urgencias y Cuidado CríticoGómez Tovar, Luz Omaira [0000-0003-1054-8697]Gómez Tovar, Luz Omaira [0001509431]Gómez Tovar, Luz Omaira [57112723700]Gómez Tovar, Luz Omaira [Luz-Gomez-Tovar-2]Gómez Tovar, Luz Omaira [fJIhbO8AAAAJ&hl]2023-01-20T17:35:27Z2023-01-20T17:35:27Z2022-11-29https://repositorio.unal.edu.co/handle/unal/83048Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, gráficas, tablasObjetivo: determinar la efectividad de la intervención de enfermería basada en el Modelo de Síntomas Dinámicos (MSD) y en evidencia científica, frente al cuidado cotidiano, para la reducción de la incidencia y duración del delirium en personas en cuidados intensivos. Método: se emplearon dos fases, diseño y evaluación de la intervención. El diseño siguió las recomendaciones de Sidani desde el enfoque teórico con aplicación del MSD y desde el enfoque empírico con una revisión sistemática. La evaluación de la intervención se realizó con un ensayo clínico aleatorizado de grupos paralelos doble ciego. La muestra fueron 213 personas en UCI. El análisis empleó estadística analítica, paramétrica y no paramétrica. Resultados: se diseñó la intervención denominada Dynamic Delirium (DyDel) con 10 cuidados y 33 actividades. Los cuidados partieron de los componentes fisiológico, psicológico, spiritual y social, ambiental, experiencia y trayectoria del MSD. Las actividades de cada cuidado surgieron de la evidencia científica. Al probar la intervención se halló que la incidencia y duración del delirium fueron significativamente menor en el grupo intervención frente al grupo control (incidencia 5,6% Vs. 14,8%, respectivamente, (p=0.037)) (duración 0.07±0.308 Vs. 0.34±1.28, respectivamente (p=0.016)). El grupo intervención también logró más cantidad de días con dolor leve y sin uso de inmovilizaciones físicas. Conclusión: la intervención DyDel, basada en el MSD y en evidencia científica, fue multicomponente, no farmacológica y vincula a la familia, y fue efectiva para reducir el delirium en personas en UCI. Se comprobó que el conocimiento propio de enfermería mejora la práctica. (Texto tomado de la fuente).Objective: to determine the effectiveness of a nursing intervention based on the Dynamic Symptom Model (DSM) and scientific evidence, versus daily care, in reducing the incidence and duration of delirium in intensive care patients. Method: two phases were used, design and evaluation of the intervention. The design followed Sidani's recommendations from the theoretical approach with the application of the DSM and the empirical approach with a systematic review. The evaluation of the intervention was carried out with a randomized clinical trial of parallel groups, double-blind. The sample consisted of 213 ICU patients. The analysis used analytical, parametric and nonparametric statistics. Results: the intervention called Dynamic Delirium (Dydel) was designed with ten care and 33 activities. Care was based on the physiological, psychological, spiritual and social, environmental, experience and MSD trajectory components. The activities for each care were derived from scientific evidence. When testing the intervention, it was found that the incidence and duration of delirium were significantly lower in the intervention group versus the control group (incidence 5.6% vs 14.8%, respectively, (p=0.037)) (duration 0.07±0.308 vs 0.34±1.28, respectively (p=0.016)). The intervention group also achieved more days with mild pain and without the use of physical immobilizations. Conclusion: the DyDel intervention, based on the DSM and scientific evidence, was multicomponent, non-pharmacological and linked to the family, and was effective in reducing delirium in ICU patients. It was proven that nursing knowledge improves practice.Incluye anexosDoctoradoDoctor en EnfermeríaMetodología: se emplearon dos fases, diseño y evaluación de la intervención. El diseño siguió las recomendaciones de Sidani desde el enfoque teórico con aplicación del Modelo de los Síntomas Dinámicos, y desde el enfoque empírico con una revisión sistemática. La evaluación de la intervención se realizó con un ensayo clínico aleatorizado de grupos paralelos doble ciego.Construcción de modelos de cuidado para el paciente en situaciones de urgencia y cuidado críticoxviii, 173 páginasapplication/pdfspaUniversisad Nacional de ColombiaBogotá - Enfermería - Doctorado en EnfermeríaFacultad de EnfermeríaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::614 - Medicina Forense; incidencia de lesiones, heridas, enfermedades; medicina preventiva públicaTrastornos Mentales/enfermeríaDelirio/enfermeríaMental Disorders/nursingDelirium/nursingDeliriumEnfermería de Cuidados CríticosInvestigación en EnfermeríaAtención de EnfermeríaTeoría de enfermeríaEnsayo ClínicoCritical Care NursingNursing ResearchNursing CareNursing TheoryClinical TrialServicio de enfermeríaNursingIntervención de enfermería para reducir incidencia y duración del delirium en personas en cuidados intensivosNursing intervention to reduce incidence and duration of delirium in patients in intensive careTrabajo de grado - Doctoradoinfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_db06Texthttp://purl.org/redcol/resource_type/TDBiremeAmerican Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders [Internet]. 5a Edition. Diagnostic and Statistical Manual of Mental Disorders. Washington; 2013. 991 p. Available from: https://cdn.website-editor.net/30f11123991548a0af708722d458e476/files/uploaded/DSM%2520V.pdfBurry LD, Williamson DR, Mehta S, Perreault MM, Mantas I, Mallick R, et al. Delirium and exposure to psychoactive medications in critically ill adults: A multi-centre observational study. J Crit Care [Internet]. 2017;42:268–74. Available from: https://doi.org/10.1016/j.jcrc.2017.08.003Mitchell ML, Keane S, Rattrayf JE, Hullg AM, Davisd C, Murfieldb JE, et al. A family intervention to reduce delirium in hospitalised ICU patients: A feasibility randomised controlled trial. Intensive Crit Care Nurs [Internet]. 2017;40(9):77–84. Available from: http://doi.org/10.1016/j.iccn.2017.01.001Lee A, Mu L, Chiu H, Gin T, Underwood MJ, Cth F, et al. Effect of motor subtypes of delirium in the intensive care unit on fast-track failure after cardiac surgery. J Thorac Cardiovasc Surg [Internet]. 2018;155(1):268-275.e1. Available from: https://doi.org/10.1016/j.jtcvs.2017.08.139Tian J, Chen X, Liu D. Prediction of length of hospital stay and mortality in patients with delirium: A prospective cohort analysis of 200 icu patients. J Biol Regul Homeost Agents [Internet]. 2018;32(3):681–5. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29921399Henao Castaño ÁM, Amaya Rey MCDP. Estudio piloto: Monitoreo del delirium en pacientes adultos despiertos con ventilación mecánica en la Unidad de Cuidado Intensivo. Conoc en Enfermería. 2017;1(1):4–12Zamoscik K, Godbold R, Freeman P. Intensive care nurses’ experiences and perceptions of delirium and delirium care. Intensive Crit Care Nurs [Internet]. 2017;40:94–100. Available from: http://dx.doi.org/10.1016/j.iccn.2017.01.003Barr J, Fraser G, Puntillo K, Wesley E, Gélinas C, Dasta J, et al. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit: Executive summary. Am J Heal Pharm [Internet]. 2013;70:53–8. Available from: http://www.ajhp.org/content/70/1/53.long?sso-checked=trueDevlin JW, Skrobik Y, Gélinas C, Needham DM, Slooter AJC, Pandharipande PP, et al. Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Crit Care Med [Internet]. 2018;46(9):825–73. Available from: https://doi.org/10.1097/CCM.0000000000003299Baron R, Binder A, Biniek R, Braune S, Buerkle H, Dall P, et al. Evidence and consensus based guideline for the management of delirium, analgesia, and sedation in intensive care medicine. Revision 2015 (DAS-Guideline 2015). Ger Med Sci [Internet]. 2015;13(12):42. Available from: https://doi.org/10.3205/000223Von Rueden KT, Wallizer B, Thurman P, McQuillan K, Andrews T, Merenda J, et al. Delirium in Trauma Patients: Prevalence and Predictors. Crit Care Nurse [Internet]. 2017;37(1):40–9. Available from: //doi.org/10.4037/ccn2017373 40Donovan AL, Matthew Aldrich J, Kendall Gross A, Barchas DM, Thornton KC, Schell-Chaple HM, et al. Interprofessional care and teamwork in the ICU. Crit Care Med. 2018;46(6):980–90.Karabulut N, Aktas YY. Nursing Management of Delirium in the Postanesthesia Care Unit and Intensive Care Unit. J PeriAnesthesia Nurs [Internet]. 2016;31(5):397–405. Available from: http://doi.org/10.1016/j.jopan.2014.10.006Gómez Tovar LO, Henao Castaño AM. Analysis of Delirium From the Dynamic Symptoms Model: A Literature Review. Crit Care Nurs Q. 2020;43(3):312–36.Sidani S, Jo Braden C. Design, Evaluation, and Translation of Nursing Interventions. Design, Evaluation, and Translation of Nursing Interventions. 2013. 1–304 p.Fawcett J. Analysis and Evaluation of Contemporary Nursing Knowledge: Nursing Models and Theories. Philadelphia; 1992. 812 p.Pinho C, Cruz S, Santos A, Abelha FJ. Postoperative delirium: age and low functional reserve as independent risk factors. J Clin Anesth [Internet]. 2016;33:507–13. Available from: http://dx.doi.org/10.1016/j.jclinane.2015.09.002Zhang W, Hu W, Shen M, Ye X, Huang Y, Sun Y. Profiles of delirium and the clinical outcomes of patients who underwent coronary artery bypass grafting : a prospective study from. J Clin Nurs [Internet]. 2016;25:631–41. Available from: https://doi.org/10.1111/jocn.13089Smulter N, Claesson H, Gustafson Y, Olofsson B. Delirium after cardiac surgery: incidence and risk factors†. Interact Cardiovasc Thorac Surg. 2013;17(July):790–6.Svenningsen H, Tønnesen EK, Videbech P, Frydenberg M, Christensen D. Intensive care delirium – effect on memories and health-related quality of life – a follow-up study. J Clin Nurs [Internet]. 2013;23:634–44. Available from: https://doi.org/10.1111/jocn.12250Patel J, Baldwin J, Bunting P, Laha S. The effect of a multicomponent multidisciplinary bundle of interventions on sleep and delirium in medical and surgical intensive care patients. Anaesthesia [Internet]. 2014;69:540–9. Available from: https://doi.org/10.1111/anae.12638Park SA, Tomimaru Y, Shibata A, Miyagawa S, Noguchi K, Dono K. Incidence and Risk Factors for Postoperative Delirium in Patients After Hepatectomy. World J Surg [Internet]. 2017;41(11):2847–53. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28608014Dotti S, Bigalli D, Pouso M. Delirium in the postoperative period of cardiac surgery. Rev Uruguaya Cardiol [Internet]. 2017;32(2):150–7. Available from: http://www.scielo.edu.uy/pdf/ruc/v32n2/1688-0420-ruc-32-02-00150.pdfMesa P, Previgliano IJ, Altez S, Favretto S, Orellano M, Lecor C, et al. Delirium in a Latin American intensive care unit. A prospective cohort study of mechanically ventilated patients. Rev Bras Ter Intensiva [Internet]. 2017;29(3):337–45. Available from: https://doi.org/10.5935/0103-507x.20170058Shankar P, Mueller A, Packiasabapathy S, Gasangwa D, Patxot M, O’Gara B, et al. Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): Protocol for a prospective randomized controlled trial. Trials [Internet]. 2018;19(1):1–8. Available from: //doi.org/10.1186/s13063-018-2718-0Jaiswal SJ, McCarthy TJ, Wineinger NE, Kang DY, Song J, Garcia S, et al. Melatonin and Sleep in Preventing Hospitalized Delirium: A Randomized Clinical Trial. Am J Med [Internet]. 2018;131(9):1110-1117.e4. Available from: https://doi.org/10.1016/j.amjmed.2018.04.009Sosa FA, Roberti J, Franco MT, Kleinert MM, Patrón AR, Osatnik J. Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina. Rev Bras Ter Intensiva [Internet]. 2018;30(1):50–6. Available from: 10.5935/0103-507X.20180010Stewart C, Bench S. Evaluating the implementation of confusion assessment method-intensive care unit using a quality improvement approach. Br Assoc Crit Care Nurses [Internet]. 2018;23(4):172–8. Available from: 10.1111/nicc.12354Pan Y, Jiang Z, Wang L, Yuan C, Wng L, Zhang J, et al. Influence of physical restraint on delirium of adult patients in ICU: A nested case – control study. J Clin Nurs. 2018;27(February):1950–7.Barman A, Pradhan D, Bhattacharyya P, Dey S, Bhattacharjee A. Diagnostic accuracy of delirium assessment methods in critical care patients. J Crit Care [Internet]. 2018;44:82–6. Available from: https://doi.org/10.1016/j.jcrc.2017.10.013Ingalls MNK, Mc U, Armstrong CB, Mc U, Hester CM, Nc U, et al. The Fog of War: Delirium Prevalence in a Combat Intensive Care Unit. Mil Med [Internet]. 2016;181(3):209–12. Available from: http://doi.org/10.7205/MILMED-D-15-00064Panitchote A, Tangvoraphonkchai K, Suebsoh N, Eanmma W, Chanthonglarng B, Tiamkao S, et al. Under-recognition of delirium in older adults by nurses in the intensive care unit setting. Aging Clin Exp Res [Internet]. 2015;27(5):735–40. Available from: https://doi.org/10.1007/s40520-015-0323-6Carrasco M, Villarroel, Luis. Calderón J, Martínez, Gabriel. Andrade Maricarmen. Gonzále M. Riesgo de delirium durante la hospitalización en personas mayores: desarrollo y validación de un modelo de predicción clínica. Rev Med Chil [Internet]. 2014;142:826–32. Available from: //dx.doi.org/10.4067/S0034-98872014000700002Adam BD, Holcomb R, Buser M, Mayfield B, Thomas J. Enhancing Food Safety, Product Quality, and Value-Added in Food Supply Chains Using Whole-Chain Traceability. Int Food Agribus Manag Rev. 2016;19:191–213.Lin Y, Chen J, Wang Z. Meta-Analysis of Factors Which Influence Delirium Following Cardiac Surgery. J Card Surg. 2012;27(2):481–92.Johnson K, Diana S, Todd J, Mcfarren A, Domb A, Mangram A, et al. Early recognition of delirium in trauma patients. Intensive Crit Care Nurs [Internet]. 2016;34:28–32. Available from: http://dx.doi.org/10.1016/j.iccn.2015.10.001Henao Castaño AM. Delirium en pacientes con ventilación mecánica en la UCI: factores asociados y cuidado de enfermería [Internet]. 2013. Available from: http://www.bdigital.unal.edu.co/10551/1/539640.2013.pdfGómez Tovar LO, Díaz Suarez L, Cortés Muñóz F. Cuidados de enfermería basados en evidencia y modelo de Betty Neuman, para controlar estresores del entorno que pueden ocasionar delirium en unidad de cuidados intensivos. Enfermería Glob. 2016;No 41:49–63.Todd OM, Gelrich L, Maclullich AM, Driessen M, Thomas C, Kreisel SH. Sleep Disruption at Home as an Independent Risk Factor for Postoperative Delirium. Am Geriatr Soc [Internet]. 2017;65(5):949–57. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28306148Watson PL, Ceriana P, Fanfulla F. Delirium: Is sleep important? Best Pract Res Clin Anaesthesiol [Internet]. 2012;26(3):355–66. Available from: http://dx.doi.org/10.1016/j.bpa.2012.08.005Henao Castaño ÁM, Amaya Rey MCDP. Delirium in awake patients with mechanical ventilation in intensive care unit. Rev Latinoam Bioética [Internet]. 2015;15(1):120–9. Available from: http://www.scielo.org.co/pdf/rlb/v15n1/v15n1a11.pdfTorres-Contreras CC, Páez-Esteban AN, Hinestrosa-Díaz del Castillo A, Rincón-Romero MK, Amaris-Vega A, Martínez-Patiño JP. Factores asociados con el delirium en pacientes críticos de una institución de salud de Bucaramanga, Colombia. Enferm Intensiva [Internet]. 2018;30(4):1–8. Available from: https://doi.org/10.1016/j.enfi.2018.03.002Durán Cárdenas LD, Suárez Salamanca N, Mesa Villamizar Y. Modelo de Betty Newman aplicado a la prevención deldelirium en pacientes de la unidad de cuidados intensivos de Los Comuneros Hospital Universitario De Bucaramanga. Universidad de Santander; 2016.Hoyos Pinedo LE. Prevalencia Y Factores De Riesgo Asociados Al Desarrollo De Delirium En La Unidad De Críticos De Gestión Salud En Cartagena De Indias. Universidad de Cartagena; 2018.Restrepo D, Duque M, Montoya L, Berrouet MC, Rojas M, Lopera G, et al. Risk Factors and Hospital Mortality in Surgical and Non-surgical Patients with Delirium. Rev Colomb Psiquiatr [Internet]. 2018;47(3):148–54. Available from: http://dx.doi.org/10.1016/j.rcp.2017.03.001Van De Pol I, Iterson M Van, Maaskant J. Intensive and Critical Care Nursing Effect of nocturnal sound reduction on the incidence of delirium in intensive care unit patients : An interrupted time series analysis. Intensive Crit Care Nurs [Internet]. 2017;41:18–25. Available from: http://dx.doi.org/10.1016/j.iccn.2017.01.008Shehabi Y, Riker RR, Bokesch PM, Wisemandle W, Shintani A, Ely EW. Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients. Crit Care Med. 2010;38(12):2311–8.Henao Castaño AM, Amaya Rey MCDP. Nursing and patients with delirium: a literature review. Investig y Educ en enfermería [Internet]. 2014;32(1):148–56. Available from: https://aprendeenlinea.udea.edu.co/revistas/index.php/iee/article/view/18614/15969Teoria de mediano rango hilando investigacion y practica para crear conocimiento para el nuevo milenio Lierh, Smith 1999.pdf.Mori S, Takeda JRT, Fernanda Souza Angotti Carrara CRC, Zanei SSV, Whitaker IY. Incidência e fatores relacionados ao delirium em Unidade de Terapia Intensiva. Rev Esc Enferm [Internet]. 2016;50(4):587–93. Available from: //dx.doi.org/10.1590/S0080-623420160000500007Hickin SL, White S, Knopp-sihota J. Intensive and Critical Care Nursing Nurses ’ knowledge and perception of delirium screening and assessment in the intensive care unit : Long-term effectiveness of an education-based knowledge translation intervention. Intensive Crit Care Nurs [Internet]. 2017;41:43–9. Available from: http://dx.doi.org/10.1016/j.iccn.2017.03.010Pollock JS, Hollenbeck RD, Wang L, Holmes B, Young MN, Peters M, et al. Delirium in survivors of Cardiac Arrest Treated with Mild Therapeutic Hypothermia. Am J Crit Care [Internet]. 2016;25(4):81–90. Available from: https://dx.doi.org/10.4037/ajcc201658Gélinas C, Bérubé M, Chevrier A, Pun BT, Ely DEW, Skrobik Y, et al. Delirium Assessment Tools for Use in Critically Ill Adults: A Psychometric Analysis and Systematic Review. CriticalCareNurse [Internet]. 2018;38(1):38–50. Available from: https://doi.org/10.4037/ccn2018633Marra A, Wesley E, Pandharipande PP, Patel MB. The ABCDEF Bundle in Critical Care. Crit Care Clin [Internet]. 2017;33(2):225–43. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351776/Boehm L, Vasilevskis E, Dietrich MS, Wells N, Wesley E, Pandharinpande P, et al. Organizational Domains and Variation in Attitudes of Intensive Care Providers Toward The ABCDE Bundle. Am J Crit Care [Internet]. 2017;26(3):18–28. Available from: https://doi.org/10.4037/ajcc2017297Faustino TN, Pedreira LC, Freitas YS de, Silva RM de O, Amaral JB do. Prevention and monitoring of delirium in older adults: an educational intervention. Rev Bras Enferm [Internet]. 2016;69(4):725–32. Available from: http://doi.org/10.1590/0034-7167.2016690416iGirard T, Pandharipande P, Wesley E. Delirium in the Intensive Care Unit. Crit Care [Internet]. 2008;12(1):1–9. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2391269/Page V, Wesley E. Delirium in Critical Care: Core Critical Care. [Internet]. First Ed. Vol. 28, Intensive & Critical Care Nursing. Cambridge; 2012. 251 p. Available from: http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=2011609350&site=ehost-live&scope=sitePage VJ, Wesley E. Delirium in Critical Care. Second Edi. Cambridge UK: Cambridge University Press; 2015. 228 p.Heras La Calle G. Humanizando los cuidados intensivos, Presente y Futuro centrado en las personas [Internet]. Primera Ed. Patient experience and co-creation in health. Madrid: Distribuna; 2017. 325 p. Available from: https://healthcocreation.wordpress.com/2014/12/09/humanizando-los-cuidados-intensivos/Cerejeira J, Firmino H, Vaz-Serra A, Mukaetova-Ladinska EB. The neuroinflammatory hypothesis of delirium. Acta Neuropathol [Internet]. 2010;119(6):737–54. Available from: https://link.springer.com/article/10.1007%2Fs00401-010-0674-1Maldonado JR. Neuropathogenesis of delirium: Review of current etiologic theories and common pathways. Am J Geriatr Psychiatry [Internet]. 2013;21(12):1190–222. Available from: https://doi.org/10.1016/j.jagp.2013.09.005Wesley E, Gautam S, Margolin R, Francis J, May L, Speroff T, et al. The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med. 2001;27(12):1892–900.Moon K, Lee S. International Journal of Nursing Studies The effects of a tailored intensive care unit delirium prevention protocol: A randomized controlled trial. Int J Nurs Stud [Internet]. 2015;52(9):1423–32. Available from: http://dx.doi.org/10.1016/j.ijnurstu.2015.04.021Amaya H. La Humanización en los lineamientos del Plan Nacional de Mejoramiento de la Calidad en Salud. 2014.Brant JM, Beck S, Miaskowski C. Building dynamic models and theories to advance the science of symptom management research. J Adv Nurs [Internet]. 2010;66(1):228–40. Available from: https://doi.org/10.1111/j.1365-2648.2009.05179.xBrant J, Dudley W, Beck S, Miaskowski C. Evolution of the Dynamic Symptoms Model. Oncol Nurs Forum [Internet]. 2016;43(5):651–4. Available from: http://onf.ons.org/onf/43/5/evolution-dynamic-symptoms-modelBrant JM, Dudley WN, Beck S, Miaskowski C. Evolution of the Dynamic Symptoms Model. Oncol Nurs Forum [Internet]. 2016;43(5):651–4. Available from: https://www.ncbi.nlm.nih.gov/pubmed/27541557Gosselin TK, Beck S, Abbott DH, Grambow SC. The Symptom Experience in Rectal Cancer Survivors. J Pain Symptom Manage [Internet]. 2016;52(5):709–18. Available from: https://doi.org/10.1016/j.jpainsymman.2016.05.027Albrecht TA. Physiologic and Psychological Symptoms Experienced by Adults With Acute Leukemia: An Integrative Literature Review. Oncol Nurs Forum [Internet]. 2014;41(3):286–95. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368444/Matzka M, Mayer H, Köck-Hódi S, Moses-Passini C, Dubey C, Jahn P, et al. Relationship between resilience, psychological distress and physical activity in cancer patients: A cross-sectional observation study. PLoS One [Internet]. 2016;11(4):1–13. Available from: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0154496Rowley-Conwy G. Intensive and Critical Care Nursing Barriers to delirium assessment in the intensive care unit: A literature review. Intensive Crit Care Nurs [Internet]. 2018;44:99–104. Available from: https://doi.org/10.1016/j.iccn.2017.09.001González-Robledo G, León J, Buitrago AF, Carvajalino S, Abril D, González V, et al. Cuidado paliativo en falla cardiaca. Rev Colomb Cardiol [Internet]. 2017;24(3):286–96. Available from: http://dx.doi.org/10.1016/j.rccar.2016.10.049Lara BA, Cataldo A, Castro R, Aguilera PR, Ruiz C, Andresen M. Medicina de urgencia y unidades de cuidados intensivos: Una alianza necesaria en busca de la mejoría de la atención de pacientes críticos TT - The impact of a better coordination between emergency and intensive care units in the care of critically ill pa. Rev Med Chil [Internet]. 2016;144:917–24. Available from: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872016000700014&lang=ptNewman MA, Smith MC, Pharris MD, Jones D. The Focus of the Discipline. Revisited. Adv Nurs Sci. 2008;31(1):16–27.Wesley Ely E. The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families. Crit Care Med [Internet]. 2017;45(2):321–30. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830123/Velasco Bueno JM, Heras La Calle G, Ortega Guerrero Á, Gómez Tello V. Manual de buenas prácticas de Humanización en las Unidades de Cuidados Intensivos [Internet]. Madrid; 2017. Available from: http://humanizandoloscuidadosintensivos.com/es/buenas-practicas/Balas MC, Vasilevskis EE, Burke WJ, Boehm L, Pun BT, Olsen KM, et al. Critical Care Nurses’ Role in Implementing the “ABCDE Bundle” Into Practice. Crit Care Nurse [Internet]. 2012;32(2):35–47. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375171/Smith MC. Regenerating Nursing’s Disciplinary Perspective. Adv Nurs Sci. 2019;42(1):3–16.Trogrlic Z, Jagt M Van Der, Bakker J, Balas MC, Ely EW, Voort PHJ Van Der, et al. A systematic review of implementation strategies for assessment, prevention, and management of ICU delirium and their effect on clinical outcomes. Crit Care [Internet]. 2015;19(157):1–17. Available from: 10.1186/s13054-015-0886-9Balas MC, Devlin JW, Verceles AC, Morris P, Wesley Ely E, Cartin-Ceba R, et al. Adapting the ABCDEF Bundle to Meet the Needs of Patients Requiring Prolonged Mechanical Ventilation in the Long-Term Acute Care Hospital Setting: Historical Perspectives and Practical Implications. Tennessee Semin Respir Crit Care Med [Internet]. 2016;37:119–35. Available from: 10.1055/s-0035-1570361Luetz A, Weiss B, Boettcher S, Burmeister J, Wernecke KD, Spies C. Routine delirium monitoring is independently associated with a reduction of hospital mortality in critically ill surgical patients: A prospective, observational cohort study. J Crit Care [Internet]. 2016;35:168–73. Available from: http://dx.doi.org/10.1016/j.jcrc.2016.05.028Boehm BLM, Dietrich MS, Vasilevskis EE, Wells N, Pandharipande P, Wesley E, et al. Perceptions of Workload Burden and Adherence to ABCDE Bundle Among intensive Care Providers. Am J Crit Care [Internet]. 2017;26(4):38–47. Available from: https://doi.org/10.4037/ajcc2017544Prescott HC, Costa DK. Improving Long-Term Outcomes After Sepsis. Crit Care Clin [Internet]. 2018;34(1):175–88. Available from: https://doi.org/10.1016/j.ccc.2017.08.013Barnes-Daly MA, Phillips G, Ely EW. Improving hospital survival and reducing brain dysfunction at Seven California Community Hospitals: Implementing PAD guidelines via the ABCDEF bundle in 6,064 patients. Crit Care Med [Internet]. 2017;45(2):171–8. Available from: https://doi.org/10.1097/CCM.0000000000002149Mart MF, Brummel NE, Wesley E. The ABCDEF Bundle for the Respiratory Therapist. Respir Care [Internet]. 2019;64(12):1561–73. Available from: https://doi.org/10.4187/respcare.07235Marra A, Pandharipande PP, Patel MB. Intensive Care Unit Delirium and Intensive Care Unit–Related Posttraumatic Stress Disorder. Surg Clin North Am [Internet]. 2017;97(6):1215–35. Available from: https://doi.org/10.1016/j.suc.2017.07.008Morandi A, Piva S, Ely EW, Myatra SN, Salluh JIF, Amare D, et al. Worldwide ABCDEF (Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium monitoring/management, Early exercise/mobility, and Family Empowerment) Survey. Crit Care Med [Internet]. 2017;45(11):1111–22. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640479/Sosnowski K, Mitchell ML, White H, Morrison L, Sutton J, Sharratt J, et al. A feasibility study of a randomised controlled trial to examine the impact of the ABCDE bundle on quality of life in ICU survivors. Pilot Feasibility Stud [Internet]. 2018;4(1):1–12. Available from: https://doi.org/10.1186/s40814-017-0224-xBrenda T. Pun, Balas MC, Barnes-Daly MA, Thompson JL, J. Aldrich M, Barr J, et al. Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. Crit Care Med [Internet]. 2019;47(1):139–48. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298815/Girard TD. “Wake Up and Breathe” Protocol Spontaneous Awakening Trials (SATs) + Spontaneous Breathing Trials (SBTs). Lancet [Internet]. 2008;2008(371):126–34. Available from: papers2://publication/uuid/0066DE15-A7ED-470B-AF2A-E094E16E0535Klompas M, Anderson D, Trick W, Babcock H, Kerlin MP, Li L, et al. The preventability of ventilator-associated events: The CDC Prevention Epicenters Wake Up and Breathe Collaborative. Am J Respir Crit Care Med [Internet]. 2015;191(3):292–301. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447286/McGinn K, Miller R, Ding L, Brevard S., Simmos J., Kahn S. 200 Spontaneous Breathing and Awakening Trials Plus a Multimodal Sedation/ Agitation Protocol Decrease Vent Days and Benzodiazepine Use in the Burn ICU. J Burn Care Res [Internet]. 2018;39(1):66-. Available from: https://doi.org/10.1093/jbcr/iry006.123Devlin JW, Pohlman AS. Everybody, every day: An “Awakening and breathing coordination, delirium monitoring/management, and early exercise/mobility” culture is feasible in your ICU. Crit Care Med [Internet]. 2014;42(5):1280–1. Available from: https://journals.lww.com/ccmjournal/Citation/2014/05000/Everybody,_Every_Day___An__Awakening_and_Breathing.30.aspxBalas MC, Weinhouse GL, Denehy L, Chanques G, Rochwerg B, Misak CJ, et al. Interpreting and Implementing the 2018 Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption Clinical Practice Guideline. Crit Care Med [Internet]. 2018;46(9):1464–70. Available from: https://doi.org/10.1097/CCM.0000000000003307Sessler CN, Gosnell MS, Grap MJ, Brophy GM, O’Neal P V., Keane KA, et al. The Richmond Agitation-Sedation Scale: Validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med. 2002;166(10):1338–44.Rojas-Gambasica JA, Valencia-Moreno A, Nieto-Estrada VH, Méndez-Osorio P, Molano-Franco D, Jiménez-Quimbaya ÁT, et al. Validación transcultural y lingüística de la escala de sedación y agitación Richmond al español. Rev Colomb Anestesiol [Internet]. 2016;44(3):218–23. Available from: http://dx.doi.org/10.1016/j.rca.2016.04.003Shetty RM, Bellini A, Wijayatilake DS, Hamilton MA, Jain R, Karanth S, et al. BIS monitoring versus clinical assessment for sedation in mechanically ventilated adults in the intensive care unit and its impact on clinical outcomes and resource utilization. Cochrane Database Syst Rev. 2018;2018(2).Cullen E, Balas MC. Delirium monitoring and management in the acute care setting. Nurse Pract. 2017;42(12):37–42.Miranda F, Arevalo‐Rodriguez I, Díaz G, Gonzalez F, Plana MN, Zamora J, et al. Confusion Assessment Method for the intensive care unit (CAM‐ICU) for the diagnosis of delirium in adults in critical care settings. Cochrane Database Syst Rev [Internet]. 2018;(9). Available from: http://dx.doi.org/10.1002/14651858.CD013126American Society of Anesthesiologists Task Force on Moderate Procedural Sedation and Analgesia, the American Association of Oral and Maxillofacial Surgeons, American College of Radiology, American Dental Association, American Society of Dentist Anesthesio and S of IR. Practice Guidelines for Moderate Procedural Sedation and Analgesia 2018. Anesthesiology [Internet]. 2018;128(3):437–79. Available from: https://anesthesiology.pubs.asahq.org/article.aspx?articleid=2670190NICE. Delirium: pre Delirium: prevention, diagnosis and ention, diagnosis and management management Clinical guideline [Internet]. 2010. Available from: https://www.nice.org.uk/guidance/cg103/resources/delirium-prevention-diagnosis-and-management-pdf-174507018181Munro CL, Cairns P, Ji M, Calero K, Anderson WM, Liang Z. Delirium prevention in critically ill adults through an automated reorientation intervention e A pilot randomized controlled trial. Hear Lung J Acute Crit Care [Internet]. 2017;46(4):234–8. Available from: http://dx.doi.org/10.1016/j.hrtlng.2017.05.002Rivosecchi RM, Kane-Gill SL, Svec S, Campbell S, Smithburger PL. The implementation of a nonpharmacologic protocol to prevent intensive care delirium. J Crit Care [Internet]. 2016;31(1):206–11. Available from: http://dx.doi.org/10.1016/j.jcrc.2015.09.031Voyer P, Champoux N, Desrosiers J, Landreville P, Mccusker J, Monette J, et al. Recognizing acute delirium as part of your routine [ RADAR ]: a validation study. BioMed Cent [Internet]. 2015;14(19):1–13. Available from: https://bmcnurs.biomedcentral.com/articles/10.1186/s12912-015-0070-1Thomas E, Smith JE, Forrester AD, Heider G, Jadotte YT, Holly C. The effectiveness of non-pharmacological multi-component interventions for the prevention of delirium in non-intensive care unit older adult hospitalized patients: a systematic review protocol. JBI Database Syst Rev Implement Reports [Internet]. 2013;11(7):361–74. Available from: https://insights.ovid.com/crossref?an=01938924-201311070-00011Litton E, Carnegie V, Elliott R, Webb SAR. The Efficacy of Earplugs as a Sleep Hygiene Strategy for Reducing Delirium in the ICU: A Systematic Review and Meta-Analysis*. Crit Care Med [Internet]. 2016;44(5):992–9. Available from: https://doi.org/10.1097/CCM.0000000000001557Litton E, Elliott R, Thompson K, Nicola W, Sppelt I, Webb S. Using Clinically Accessible Tools to Measure Sound Levels and Sleep Disruption in the ICU: A Prospective Multicenter Observational Study. Crit Care Med [Internet]. 2017;45(6):966–71. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28362644Corcoran JR, Herbsman JM, Bushnik T, Van Lew S, Stolfi A, Parkin K, et al. Early Rehabilitation in the Medical and Surgical Intensive Care Units for Patients With and Without Mechanical Ventilation: An Interprofessional Performance Improvement Project. PM R [Internet]. 2017;9(2):113–9. Available from: http://dx.doi.org/10.1016/j.pmrj.2016.06.015Page VJ, Casarin A, Ely EW, Zhao XB, McDowell C, Murphy L, et al. Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation (MoDUS): a randomised, double-blind, placebo-controlled trial. Lancet Respir Med [Internet]. 2017;5(9):727–37. Available from: http://dx.doi.org/10.1016/S2213-2600(17)30234-5Zhang W, Sun Y, Liu Y, Qiu W, Ye X, Zhang G, et al. A nursing protocol targeting risk factors for reducing postoperative delirium in patients following coronary artery bypass grafting: Results of a prospective before-after study. Int J Nurs Sci [Internet]. 2017;4(2):81–7. Available from: http://dx.doi.org/10.1016/j.ijnss.2017.02.002Freeman S, Hallett C, Mchugh G. Physical restraint: experiences, attitudes and opinions of adult intensive care unit nurses. Nurs Crit Care [Internet]. 2015;21(2):78–87. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/nicc.12197Birge AÖ, Aydin HT. The effect of nonpharmacological training on delirium identification and intervention strategies of intensive care nurses. Intensive Crit Care Nurs [Internet]. 2017;41:33–42. Available from: https://doi.org/10.1016/j.iccn.2016.08.009Davidson JE, Winkelman C, Gélinas C, Dermenchyan A. Pain, Agitation, and Delirium Guidelines: Nurses’ Involvement in Development and Implementation. Crit Care Nurse [Internet]. 2015;35(3):17–33. Available from: https://doi.org/10.4037/ccn2015824White BL, Zomorodi M. Perceived and actual noise levels in critical care units. Intensive Crit Care Nurs [Internet]. 2017;38:18–23. Available from: http://dx.doi.org/10.1016/j.iccn.2016.06.004Girard TD, Exline MC, Carson SS, Hough CL, Rock P, Gong MN, et al. Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness. N Engl J Med [Internet]. 2018;379:2506–16. Available from: http://www.nejm.org/doi/10.1056/NEJMoa1808217Reade MC, Eastwood GM, Bellomo R, Bailey M, Bersten A, Cheung B, et al. Effect of dexmedetomidine added to standard care on ventilator-free time in patients with agitated delirium a randomized clinical trial. JAMA - J Am Med Assoc [Internet]. 2016;315(14):1460–8. Available from: https://doi.org/10.1001/jama.2016.2707Morris PE, Goad A, Thompson C, Taylor K, Harry B, Passmore L, et al. Early intensive care unit mobility therapy in the treatment of acute respiratory failure. Crit Care Med. 2008;36(8):2238–43.Nydahl P, Sricharoenchai T, Chandra S, Sari F, Ma MPH, Huang M, et al. Safety of Patient Mobilization and Rehabilitation in the ICU: Systematic Review with Meta- Analysis. Am Thorac Soc. 2017;6:1–67.Schweickert WD, Pohlman MC, Pohlman AS, Nigos C, Pawlik AJ, Esbrook CL, et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled trial. Lancet [Internet]. 2009;373(9678):1874–82. Available from: http://dx.doi.org/10.1016/S0140-6736(09)60658-9Vanderbilt University Medical Center. Early Mobility and Exercise [Internet]. Icu delirium. 2013. p. 1–7. Available from: http://www.icudelirium.org/earlymobility.htmlMitchell ML, Kean S, Rattray JE, Hull AM, Davis C, Murfield JE, et al. A family intervention to reduce delirium in hospitalised ICU patients: A feasibility randomised controlled trial. Intensive Crit Care Nurs [Internet]. 2017;40:77–84. Available from: http://dx.doi.org/10.1016/j.iccn.2017.01.001Davidson JE, Aslakson RA, Long AC, Puntillo KA, Kross EK, Hart J, et al. Guidelines for Family-Centered Care in the Neonatal, Pediatric, and Adult ICU. Crit Care Med [Internet]. 2017;45(1):103–28. Available from: https://insights.ovid.com/pubmed?pmid=27984278Liput SA, Kane-Gill SL, Seybert AL, Smithburger PL. A review of the perceptions of healthcare providers and family members toward family involvement in active adult patient care in the ICU. Crit Care Med. 2016;44(6):1191–7.Garrouste-Orgeas M, Max A, Lerin T, Grégoire C, Ruckly S, Kloeckner M, et al. Impact of proactive nurse participation in ICU family conferences: A mixed-method study. Crit Care Med. 2016;44(6):1116–28.Kram SL, Dibartolo MC, Hinderer K, Jones RA. Implementation of the ABCDE Bundle to Improve Patient Outcomes in the Intensive Care Unit in a Rural Community Hospital. Dimens Crit Care Nurs [Internet]. 2015;34(5):250–8. Available from: https://doi.org/10.1097/DCC.0000000000000129Kang J, Lee M, Ko H, Kim S, Yun S, Jeong Y, et al. Effect of nonpharmacological interventions for the prevention of delirium in the intensive care unit: A systematic review and meta-analysis. J Crit Care [Internet]. 2018;48:372–84. Available from: https://www.sciencedirect.com/science/article/pii/S0883944118310013?dgcid=rss_sd_allMartínez F, Donoso AM, Marquez C, Labarca E. Implementing a multicomponent intervention to prevent delirium among critically ill patients. Crit Care Nurse [Internet]. 2017;37(6):36–47. Available from: http://doi.org/10.4037/ccn2017531Rosa RG, Tonietto TF, Da Silva DB, Gutierres FA, Ascoli AM, Madeira LC, et al. Effectiveness and safety of an extended icu visitation model for delirium prevention: A before and after study. Crit Care Med. 2017;45(10):1660–7.Mailhot T, Cossette S, Côté J, Bourbonnais A, Côté MC, Lamarche Y, et al. A post cardiac surgery intervention to manage delirium involving families: a randomized pilot study. Nurs Crit Care. 2017;22(4):221–8.Johnson K, Curry V, Steubing A, Diana S, Mccray A, Mcfarren A, et al. A non-pharmacologic approach to decrease restraint use. Intensive Crit Care Nurs [Internet]. 2016;34:20–7. Available from: http://dx.doi.org/10.1016/j.iccn.2015.08.004Smith JM, Aman MN Van. Assessment of Delirium in Intensive Care Unit Patients : Educational Strategies. J Contin Edication Nurs. 2017;48(5):239–44.Fraser V, Cossette S, Mailhot T, Brisebois A. Evaluation of an Intervention With Nurses for Delirium Detection After Cardiac Surgery. Worldviews Evidence-Based Nurs. 2018;15(1):38–44.Marino J, Bucher D, Beach M, Cooper B. Implementation of an Intensive Care Unit Delirium Protocol. Dimens Crit Care Nurs. 2015;34(5):273–84.Speed G. The Impact of a Delirium Educational Intervention With Intensive Care Unit Nurses. Clin Nurse Spec. 2015;29(2):89–94.Stadtmann MP, Maercker A, Binder J, Schnepp W. Why do I to suffer? Symptom management, views, and experiences of relatives of persons with CPTSD: a grounded theory study. J Patient-Reported Outcomes [Internet]. 2018;2(1):1–11. Available from: https://doi.org/10.1186/s41687-018-0070-5Lin Y, Docherty SL, Porter LS, Bailey DE. Symptom experience and self-management for multiple co-occurring symptoms in patients with gastric cancer: A qualitative study. Eur J Oncol Nurs [Internet]. 2020;49. Available from: https://doi.org/10.1016/j.ejon.2020.101860Whisenant M, Wong B, Mitchell S, Beck S, Mooney K. Distinct Trajectories of Fatigue and Sleep Disturbance in Women Receiving Chemotherapy for Breast Cancer. Oncol Nurs Forum [Internet]. 2017;44(6):739–50. Available from: http://onf.ons.org/onf/44/6/distinct-trajectories-fatigue-and-sleep-disturbance-women-receiving-chemotherapy-breastWhisenant M, Wong B, Mitchell SA, Beck SL, Mooney K. Symptom Trajectories Are Associated With Co-Occurring Symptoms During Chemotherapy For Breast Cancer. J Pain Symptom Manage [Internet]. 2018; Available from: https://linkinghub.elsevier.com/retrieve/pii/S0885392418310716%0Ahttp://www.ncbi.nlm.nih.gov/pubmed/30453052Whisenant M, Wong B, Mitchell SA, Beck SL, Mooney K. Trajectories of Depressed Mood and Anxiety during Chemotherapy for Breast Cancer. Cancer Nurs [Internet]. 2020;43(1):22–31. Available from: https://doi.org/10.1097/NCC.0000000000000670Partington L. Researchers The presence and intensity and the related changes over time of physical symptoms in the dying phase : A prospective cohort study of residents dying in care homes [Internet]. Lancaster University; 2020. Available from: https://doi.org/10.17635/lancaster/thesis/1102Pinzón Casas EY. Validación del Instrumento PSCAM-ICU en su versión en español [Internet]. Universidad Nacional de Colombia; 2018. Available from: https://repositorio.unal.edu.co/handle/unal/69806Shin H. Physical and Psychological Late Effects on Health-Related Quality of Life in Long-Term Survivors of Childhood Cancer. University of North Carolina; 2017.Riegel B, Jaarsma T, Lee CS, Strömberg A. Integrating Symptoms Into the Middle-Range Theory of Self-Care of Chronic Illness. Adv Nurs Sci. 2019;42(3):206–15.White LL, Cohen MZ, Berger AM, Kupzyk KA, Bierman PJ. Self-efficacy for management of symptoms and symptom distress in adults with cancer: An integrative review. Oncol Nurs Forum [Internet]. 2019;46(1):113–28. Available from: https://doi.org/10.1188/19.ONF.113-128Mohr C, Jensen C, Padden N, Besel JM, Brant JM. Peppermint Essential Oil for Nausea and Vomiting in Hospitalized Patients: Incorporating Holistic Patient Decision Making Into the Research Design. J Holist Nurs [Internet]. 2020;1–9. Available from: https://doi.org/10.1177/0898010120961579Fawcett J, DeSanto Madeya S. Contemporary Nursing Knowledge. Analysis and Evaluation of Nursing Models and Theories. Third Edit. Philadelphia: F.A. Davis Company; 2013. 642 p.Monti EJ, Tingen MS. Multiple Paradigms of Nursing Science. Adv Nurs Sci [Internet]. 1999;21(4):64–80. Available from: https://doi.org/10.1097/00012272-199906000-00010Fawcett J, Garity J. Evaluating Research for Evidence-Based Nursing Practice. Company FAD, editor. Philadelphia; 2009. 337 p.Bueno-Robles LS. Aspectos ontológicos y epistemológicos de las visiones de enfermería inmeras en el quehacer profesional. Cienc y Enfermería. 2011;XVII(1):37–43.Newman MA, Smith MC, Pharris MD, Jones D. The focus of the discipline of nursing. Adv Nurs Sci [Internet]. 2008;31(1):16–27. Available from: http://search.ebscohost.com/login.aspx?direct=true&db=cin20&AN=107510098&site=ehost-liveFriedman LM, Furberg CD, DeMets DL. Fundamentals of Clínical Trials. 4th Editio. Journal of Chemical Information and Modeling. New York: Springer; 2010. 464 p.Lemeshow S, Hosmer DW, Klar J, Lwanga SK. Adequacy of Sample Size in Health Studies. World Health Organization. New York: John Wiley & Sons; 1999.Wesley E, Margolin R, Francis J, May L, Truman B, Dittus R, et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med. 2001;29(7):1370–9.Tobar E, Romero C, Galleguillos T, Fuentes P, Cornejo R, Lira MT, et al. Método para la evaluación de la confusión en la unidad de cuidados intensivos para el diagnóstico de delírium: adaptación cultural y validación de la versión en idioma español. Med Intensiva. 2010;34(1):4–13.Toro AC, Escobar LM, Franco JG, Díaz-Gómez JL, Muñoz JF, Molina F, et al. Versión en español del método para la evaluación de la confusión en cuidados intensivos, estudio piloto de validación. Med Intensiva. 2010;34(1):14–21.Salinas Mendez MA. Escalas para valoración del dolor en pacientes sometidos a ventilación mecáninca con sedación y analgesia: revisión integrativa [Internet]. Universidad de Sonora; 2019. Available from: http://www.repositorioinstitucional.uson.mx/handle/unison/4156Pardo C, Muñoz T, Chamorro C, Grupo de trabajo de analgesia y sedación de la SEMICYUC. Monitorización del dolor. Recomendaciones del grupo de trabajo de analgesia y sedación de la SEMICYUC. Med Intensiva [Internet]. 2006;30(8):379–85. Available from: https://doi.org/10.1016/s0210-5691(06)74552-1Eizaga-Rebollar R, García-Palacios MV. Escalas de valoración del dolor [Internet]. Mexico; 2015. 82 p. Available from: http://www.1aria.com/docs/sections/areaDolor/escalasValoracion/EscalasValoracionDolor.pdfVicente Herrero MT, Delgado Bueno S, Bandrés Moyá F, Ramírez Iñiguez de la Torre MV, Capdevila García L. Valoración del dolor. Revisión Comparativa de Escalas y Cuestionarios. Rev la Soc Española del Dolor. 2018;25(4):228–36.Rivas E, Alarcón M, Gatica V, Neupayante K, Schneider MB. Escalas de valoración de dolor en pacientes críticos no comunicaticos. Enfermería Cuid Humaniz [Internet]. 2018;7:115–29. Available from: http://www.scielo.edu.uy/pdf/ech/v7n1/2393-6606-ech-7-01-57.pdfGonzález Pérez LX. Adaptación de la escala de Campbell para la evaluación del dolor en una unidad de cuidado intensivo de la ciudad de Bogotá [Internet]. Universidad del Rosario; 2019. Available from: https://repository.urosario.edu.co/handle/10336/19810?show=fullThabane L, Mbuagbaw L, Zhang S, Samaan Z, Marcucci M, Ye C, et al. A tutorial on sensitivity analyses in clinical trials: The what, why, when and how. BMC Med Res Methodol [Internet]. 2013;13(1). Available from: https://doi.org/10.1186/1471-2288-13-92McCoy CE. Understanding the intention-to-treat principle in randomized controlled trials. West J Emerg Med [Internet]. 2017;18(6):1075–8. Available from: https://doi.org/10.5811/westjem.2017.8.35985Manterola C, Otzen T. Los Sesgos en Investigación Clínica. Int J Morphol [Internet]. 2015;33(3):1156–64. Available from: https://doi.org/10.4067/s0717-95022015000300056Hernández-Avila M, Garrido F, Salazar-Martínez E. Sesgos en estudos epidemiológicos. Salud Publica Mex [Internet]. 2000;42(5):438–46. Available from: https://www.scielosp.org/article/ssm/content/raw/?resource_ssm_path=/media/assets/spm/v42n5/3995.pdfMundial AM. Declaración de Helsinki de la AMM - Principios éticos para las Investigaciones médicas en Seres Humanos. 1964.Instituto Nacional de Salud de los Estados Unidos. Informe de Belmont [Internet]. The Belmont Report Ethical Principles and Guidelines for the Protection of Human Subjects of Research Estados Unidos de América; 1979. Available from: http://www.pcb.ub.edu/bioeticaidret/archivos/norm/InformeBelmont.pdfConsejo de Organizaciones Internacionales de las Ciencias Médicas. Pautas éticas internacionales para la investigación relacionada con la salud con seres humanos. Organización Panamericana de la Salud. 2017. 150 p.República de Colombia. Ley Estatutaria 1581 de 2012 [Internet]. Colombia; 2012. Available from: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/DE/DIJ/RESOLUCION-8430-DE-1993.PDFRepública de Colombia Gobierno Nacional. Ley 911 de 2004. Colombia; 2004.Gobierno Nacional de Colombia. Ley 1581 de 2012 [Internet]. Colombia: presidencia.gov.co; 2012 p. 301. Available from: https://www.funcionpublica.gov.co/eva/gestornormativo/norma.php?i=50364República de Colombia Ministerio de Comercio Industria y Turismo. DECRETO 1377 DE 2013 [Internet]. 1377 Colombia: Ministerio de las TIC; 2013 p. 11. Available from: https://www.funcionpublica.gov.co/eva/gestornormativo/norma.php?i=53646Gallagher E, Rogers BB, Brant JM. Cancer-Related Pain Assessment: Monitoring the effectiveness of interventions. Clin J Oncol Nursingournal Oncol Nurs [Internet]. 2015;21(3):8–13. Available from: http://doi.org/10.1188/17.CJON.S3.8-12Gómez Tovar LO, Henao Castaño ÁM. Intervenciones y efectividad del Paquete ABCDEF en el tratamiento de delirium: revisión de alcance. Av en Enfermería [Internet]. 2021;39(3):395–414. Available from: https://doi.org/10.15446/av.enferm.v39n3.85828Manterola C, Asenjo-Lobos C, Otzen T. Jerarquización de la evidencia. Niveles de evidencia y grados de recomendación de uso actual. Rev Chil infectología [Internet]. 2014;31(6):705–18. Available from: https://scielo.conicyt.cl/pdf/rci/v31n6/art11.pdfRoy C. Nursing Knowledge in the 21st Century Domain-Derived and Basic Science Practice-Shaped. Adv Nurs Sci [Internet]. 2018;42(1):28–42. Available from: http://doi.org/10.1097/ANS.0000000000000240Fawcett J. Thoughts About Thinking Theoretically and Atheoretically. Essays Nurs Sci Thoughts [Internet]. 2020;33(3):272–3. Available from: https://doi.org/10.1177/0894318420920623Chinn PL. The Discipline of Nursing: Moving Forward Boldly [Internet]. Case Western Reserve University Frances Payne Bolton School of Nursing. 2019. p. 1–31. Available from: https://nursology.net/2019-03-21-case-keynote/%0A1Fonsmark L, Hein L, Nibroe H, Bundgaard H, De Haas I, Iversen S, et al. Danish national sedation strategy. Targeted therapy of discomfort associated with critical illness. Danish society of intensive care medicine (DSIT) and the Danish society of Anesthesiology and intensive care medicine (DASAIM). Dan Med J [Internet]. 2015;62(4):C5052. Available from: https://ugeskriftet.dk/files/scientific_article_files/2018-11/b5052.pdfTang B, Wang XT, Chen WJ, Zhu SH, Chao YG, Zhu B, et al. Experts consensus on the management of delirium in critically ill patients. Zhonghua nei ke za zhi [Internet]. 2019;58(2):108–18. Available from: https://pubmed.ncbi.nlm.nih.gov/30704197/Celis-Rodríguez E, Díaz Cortés JC, Cárdenas Bolívar YR, Carrizosa González JA, Pinilla DI, Ferrer Záccaro LE, et al. Guías de práctica clínica basadas en la evidencia para el manejo de la sedoanalgesia y delirium en el paciente adulto críticamente enfermo. Med Intensiva [Internet]. 2020;44(3):171–84. Available from: https://doi.org/10.1016/j.medin.2019.07.013Vincent JL, Shehabi Y, Walsh TS, Pandharipande PP, Ball JA, Spronk P, et al. Comfort and patient-centred care without excessive sedation: the eCASH concept. Intensive Care Med [Internet]. 2016;42(6):962–71. Available from: https://doi.org/10.1007/s00134-016-4297-4Guo Y, Sun L, Li L, Jia P, Zhang J, Jiang H, et al. Impact of multicomponent, nonpharmacologic interventions on perioperative cortisol and melatonin levels and postoperative delirium in elderly oral cancer patients. Arch Gerontol Geriatr. 2016;62:112–7.Álvarez EA, Garrido MA, Tobar EA, Prieto SA, Vergara SO, Briceño CD, et al. Occupational therapy for delirium management in elderly patients without mechanical ventilation in an intensive care unit: A pilot randomized clinical trial. J Crit Care [Internet]. 2017;37:85–90. Available from: http://dx.doi.org/10.1016/j.jcrc.2016.09.002Rood PJT, Zegers M, Ramnarain D, Koopmans M, Klarenbeek T, Ewalds E, et al. The Impact of Nursing Delirium Preventive Interventions in the ICU A Multicenter Cluster-randomized Controlled Clinical Trial. Am J Respir Crit Care Med [Internet]. 2021;204(6):682–91. Available from: https://doi.org/10.1164/rccm.202101-0082OCTorres Contreras CC, Páez Esteban AN, Duran Parra M, Romero Rincón MK, Giordani da Silva C, Duarte Buitrago NP. Programa de enfermería multicomponente para prevención del delirium en pacientes críticamente enfermos : ensayo clínico aleatorizado. Rev Gaúcha Enferm [Internet]. 2021;42:e20200278. Available from: https://doi.org/10.1590/1983-1447.2021.20200278Truman B, Balas MC, Barnes-Daly MA, Thompson JL, Aldrich JM, Barr J, et al. Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults. Crit Care Med [Internet]. 2019;47(1):3–14. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298815/Facultad de Enfermería de la Universidad Nacional de ColombiaEstudiantesGrupos comunitariosInvestigadoresLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/83048/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL53061691.2022.pdf53061691.2022.pdfTesis de Doctorado en Enfermeríaapplication/pdf13555133https://repositorio.unal.edu.co/bitstream/unal/83048/2/53061691.2022.pdfdab7415f431a2e74e9544a14a2ff4294MD52THUMBNAIL53061691.2022.pdf.jpg53061691.2022.pdf.jpgGenerated Thumbnailimage/jpeg5301https://repositorio.unal.edu.co/bitstream/unal/83048/3/53061691.2022.pdf.jpg595b2876c92987fb34045e8060a5d9a2MD53unal/83048oai:repositorio.unal.edu.co:unal/830482024-08-15 23:14:41.415Repositorio Institucional Universidad Nacional de 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