In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia

Objective The aim of the present study was to evaluate the antifungal susceptibilities of isolates of Fusarium to amphotericin B, itraconazole and voriconazole.Methods The susceptibility of 44 isolates of Fusarium was tested by the E-test methodology.Results All the isolates were resistant to itraco...

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Autores:
Gaviria-Rivera, Adelaida Maria
Giraldo-López, Alejandra Dixie
Cano Restrepo, Luz Elena
Tipo de recurso:
Article of journal
Fecha de publicación:
2017
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/65440
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/65440
http://bdigital.unal.edu.co/66463/
Palabra clave:
36 Problemas y servicios sociales, asociaciones / Social problems and social services
61 Ciencias médicas; Medicina / Medicine and health
Fusarium
amphotericin B
voriconazole
Fusarium
anfotericina B
voriconazol
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
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network_name_str Universidad Nacional de Colombia
repository_id_str
spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Gaviria-Rivera, Adelaida Maria6c56fd42-5cdf-4b75-8d47-456f036278f6300Giraldo-López, Alejandra Dixie0049b7e3-d2c3-4ad6-bd64-6187623a4962300Cano Restrepo, Luz Elenac5d16c19-c49c-4efe-af5c-5d46b9c275203002019-07-03T00:21:36Z2019-07-03T00:21:36Z2017-11-01ISSN: 2539-3596https://repositorio.unal.edu.co/handle/unal/65440http://bdigital.unal.edu.co/66463/Objective The aim of the present study was to evaluate the antifungal susceptibilities of isolates of Fusarium to amphotericin B, itraconazole and voriconazole.Methods The susceptibility of 44 isolates of Fusarium was tested by the E-test methodology.Results All the isolates were resistant to itraconazole, and 89 % and 54,5 % were resistant to amphotericin B and voriconazole, respectively.Discussion The results confirm the high level of resistance reported, regardless of the species or the strain of Fusarium involved. The high MICs level observed are worrying and suggest that new drugs are needed.Objetivo Evaluar la susceptibilidad antifúngica in vitro de aislamientos de Fusarium a los antimicóticos amfotericina B, itraconazol y voriconazol.Métodos La susceptibilidad de 44 aislamientos clínicos de Fusarium fue evaluada por el método de difusión en disco, E-test.Resultados Todos los aislamientos fueron resistentes al itraconazol, y 89 % y 54,5 % fueron resistentes a la amfotericina B y al voriconazol, respectivamente.Discusión Los resultados confirman el alto nivel de resistencia reportado, independiente de la especie o la cepa de Fusarium involucrada. Los valores tan altos de MICs son preocupantes y sugieren la necesidad de evaluar nuevos medicamentos.application/pdfspaUniversidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina - Instituto de Salud Públicahttps://revistas.unal.edu.co/index.php/revsaludpublica/article/view/54654Universidad Nacional de Colombia Revistas electrónicas UN Revista de Salud PúblicaRevista de Salud PúblicaGaviria-Rivera, Adelaida Maria and Giraldo-López, Alejandra Dixie and Cano Restrepo, Luz Elena (2017) In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia. Revista de Salud Pública, 19 (6). pp. 800-805. ISSN 2539-359636 Problemas y servicios sociales, asociaciones / Social problems and social services61 Ciencias médicas; Medicina / Medicine and healthFusariumamphotericin BvoriconazoleFusariumanfotericina BvoriconazolIn vitro antifungal susceptibility of clinical isolates of Fusarium from ColombiaArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTORIGINAL54654-387235-1-PB.pdfapplication/pdf337682https://repositorio.unal.edu.co/bitstream/unal/65440/1/54654-387235-1-PB.pdf876e0bd445fbbc60ecd71a4561a6fdafMD51THUMBNAIL54654-387235-1-PB.pdf.jpg54654-387235-1-PB.pdf.jpgGenerated Thumbnailimage/jpeg7726https://repositorio.unal.edu.co/bitstream/unal/65440/2/54654-387235-1-PB.pdf.jpg133274b0d50ee770fde1ba0cf3d2f610MD52unal/65440oai:repositorio.unal.edu.co:unal/654402024-05-10 23:08:49.534Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co
dc.title.spa.fl_str_mv In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
title In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
spellingShingle In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
36 Problemas y servicios sociales, asociaciones / Social problems and social services
61 Ciencias médicas; Medicina / Medicine and health
Fusarium
amphotericin B
voriconazole
Fusarium
anfotericina B
voriconazol
title_short In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
title_full In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
title_fullStr In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
title_full_unstemmed In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
title_sort In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia
dc.creator.fl_str_mv Gaviria-Rivera, Adelaida Maria
Giraldo-López, Alejandra Dixie
Cano Restrepo, Luz Elena
dc.contributor.author.spa.fl_str_mv Gaviria-Rivera, Adelaida Maria
Giraldo-López, Alejandra Dixie
Cano Restrepo, Luz Elena
dc.subject.ddc.spa.fl_str_mv 36 Problemas y servicios sociales, asociaciones / Social problems and social services
61 Ciencias médicas; Medicina / Medicine and health
topic 36 Problemas y servicios sociales, asociaciones / Social problems and social services
61 Ciencias médicas; Medicina / Medicine and health
Fusarium
amphotericin B
voriconazole
Fusarium
anfotericina B
voriconazol
dc.subject.proposal.spa.fl_str_mv Fusarium
amphotericin B
voriconazole
Fusarium
anfotericina B
voriconazol
description Objective The aim of the present study was to evaluate the antifungal susceptibilities of isolates of Fusarium to amphotericin B, itraconazole and voriconazole.Methods The susceptibility of 44 isolates of Fusarium was tested by the E-test methodology.Results All the isolates were resistant to itraconazole, and 89 % and 54,5 % were resistant to amphotericin B and voriconazole, respectively.Discussion The results confirm the high level of resistance reported, regardless of the species or the strain of Fusarium involved. The high MICs level observed are worrying and suggest that new drugs are needed.
publishDate 2017
dc.date.issued.spa.fl_str_mv 2017-11-01
dc.date.accessioned.spa.fl_str_mv 2019-07-03T00:21:36Z
dc.date.available.spa.fl_str_mv 2019-07-03T00:21:36Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.issn.spa.fl_str_mv ISSN: 2539-3596
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/65440
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identifier_str_mv ISSN: 2539-3596
url https://repositorio.unal.edu.co/handle/unal/65440
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dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.spa.fl_str_mv https://revistas.unal.edu.co/index.php/revsaludpublica/article/view/54654
dc.relation.ispartof.spa.fl_str_mv Universidad Nacional de Colombia Revistas electrónicas UN Revista de Salud Pública
Revista de Salud Pública
dc.relation.references.spa.fl_str_mv Gaviria-Rivera, Adelaida Maria and Giraldo-López, Alejandra Dixie and Cano Restrepo, Luz Elena (2017) In vitro antifungal susceptibility of clinical isolates of Fusarium from Colombia. Revista de Salud Pública, 19 (6). pp. 800-805. ISSN 2539-3596
dc.rights.spa.fl_str_mv Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.spa.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
Derechos reservados - Universidad Nacional de Colombia
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia - Sede Bogotá - Facultad de Medicina - Instituto de Salud Pública
institution Universidad Nacional de Colombia
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