Estructura genética en una muestra de la población humana en la Orinoquía colombiana

ilustraciones, graficas

Autores:
Torres Jara, William Camilo
Tipo de recurso:
Fecha de publicación:
2022
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/82064
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/82064
https://repositorio.unal.edu.co/
Palabra clave:
570 - Biología::576 - Genética y evolución
Marcadores Genéticos
Cromosomas
Genetic Markers
Chromosomes
Orinoquía
genética de poblaciones
Cromosoma Y
Cultura
INDELs
STRs
Population genetics
Y Chromosome
Culture
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
id UNACIONAL2_28cae550f6d43685a7f3f817ecc6301f
oai_identifier_str oai:repositorio.unal.edu.co:unal/82064
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Estructura genética en una muestra de la población humana en la Orinoquía colombiana
dc.title.translated.eng.fl_str_mv Genetic structure in a sample of the human population in the Colombian Orinoquía
title Estructura genética en una muestra de la población humana en la Orinoquía colombiana
spellingShingle Estructura genética en una muestra de la población humana en la Orinoquía colombiana
570 - Biología::576 - Genética y evolución
Marcadores Genéticos
Cromosomas
Genetic Markers
Chromosomes
Orinoquía
genética de poblaciones
Cromosoma Y
Cultura
INDELs
STRs
Population genetics
Y Chromosome
Culture
title_short Estructura genética en una muestra de la población humana en la Orinoquía colombiana
title_full Estructura genética en una muestra de la población humana en la Orinoquía colombiana
title_fullStr Estructura genética en una muestra de la población humana en la Orinoquía colombiana
title_full_unstemmed Estructura genética en una muestra de la población humana en la Orinoquía colombiana
title_sort Estructura genética en una muestra de la población humana en la Orinoquía colombiana
dc.creator.fl_str_mv Torres Jara, William Camilo
dc.contributor.advisor.none.fl_str_mv Usaquen Martinez, William
dc.contributor.author.none.fl_str_mv Torres Jara, William Camilo
dc.contributor.researchgroup.spa.fl_str_mv Genética de Poblaciones e Identificación
dc.subject.ddc.spa.fl_str_mv 570 - Biología::576 - Genética y evolución
topic 570 - Biología::576 - Genética y evolución
Marcadores Genéticos
Cromosomas
Genetic Markers
Chromosomes
Orinoquía
genética de poblaciones
Cromosoma Y
Cultura
INDELs
STRs
Population genetics
Y Chromosome
Culture
dc.subject.other.spa.fl_str_mv Marcadores Genéticos
Cromosomas
dc.subject.other.eng.fl_str_mv Genetic Markers
Chromosomes
dc.subject.proposal.spa.fl_str_mv Orinoquía
genética de poblaciones
Cromosoma Y
Cultura
dc.subject.proposal.none.fl_str_mv INDELs
STRs
dc.subject.proposal.eng.fl_str_mv Population genetics
Y Chromosome
Culture
description ilustraciones, graficas
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2022-08-24T15:40:20Z
dc.date.available.none.fl_str_mv 2022-08-24T15:40:20Z
dc.date.issued.none.fl_str_mv 2022-06-28
dc.type.spa.fl_str_mv Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/TM
status_str acceptedVersion
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/82064
dc.identifier.instname.spa.fl_str_mv Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv https://repositorio.unal.edu.co/
url https://repositorio.unal.edu.co/handle/unal/82064
https://repositorio.unal.edu.co/
identifier_str_mv Universidad Nacional de Colombia
Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.indexed.spa.fl_str_mv RedCol
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institution Universidad Nacional de Colombia
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spelling Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Usaquen Martinez, Williamf6d0a3820e21697a2d471b99bf00cd66Torres Jara, William Camiloccdb2d2711721944d8f7cd20260fc312Genética de Poblaciones e Identificación2022-08-24T15:40:20Z2022-08-24T15:40:20Z2022-06-28https://repositorio.unal.edu.co/handle/unal/82064Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, graficasSe realizo un estudio de caracterización de una muestra de la Orinoquía colombiana, esto como parte del macroproyecto que lleva a cabo el grupo de genética de poblaciones e identificación de la Universidad Nacional de Colombia. Se utilizaron tres tipos de marcadores para esta tarea incluyendo STRs, INDELs y cromosoma Y, los resultados son concordantes con descripciones previas donde la población de la Orinoquía es genéticamente similar a las poblaciones de la región andina, esta noción contrasta con el modelo de poblamiento establecido por Tarazona-Santos, donde poblaciones del oriente del sur del continente sur americano y la región andina difieren por patrones de diversidad. Los resultados expuestos podrían extender el modelo Tarazona-Santos de las regiones de la cordillera oriental a la región de la Orinoquía ajustado a patrones biogeográficos. Adicionalmente considerando la cercanía genética de estas poblaciones, es llamativa las divergencias en otros aspectos como los biogeográficos y bioculturales, por lo cual se propone una línea de análisis basada en aspectos propios de las culturas para una compresión holística de las poblaciones. (Texto tomado de la fuente)A characterization study of a sample from the Colombian Orinoquía was carried out as part of the macroproject carried out by the population genetics and identification group of the National University of Colombia. Three types of markers were used for this task including STRs, INDELs and Y chromosome, the results are consistent with previous descriptions where the population of the Orinoquía is genetically similar to the populations of the Andean region, this notion contrasts with the established population model by Tarazona-Santos, where populations from the south east of the South American continent and the Andean region differ by patterns of diversity. The exposed results could extend the Tarazona-Santos model from the regions of the Eastern Cordillera to the Orinoquía region adjusted to biogeographical patterns. Additionally, considering the genetic proximity of these populations, the divergences in other aspects such as biogeographical and biocultural are striking, for which a line of analysis based on aspects of cultures is proposed for a holistic understanding of populations.MaestríaMagíster en Genética HumanaGenética de poblaciones y genética humana110 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Maestría en Genética HumanaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá570 - Biología::576 - Genética y evoluciónMarcadores GenéticosCromosomasGenetic MarkersChromosomesOrinoquíagenética de poblacionesCromosoma YCulturaINDELsSTRsPopulation geneticsY ChromosomeCultureEstructura genética en una muestra de la población humana en la Orinoquía colombianaGenetic structure in a sample of the human population in the Colombian OrinoquíaTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMRedColLaReferenciaAlonso, L. 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Dissecting the pre-Columbian genomic ancestry of Native Americans along the Andes–Amazonía divide. Molecular Biology and Evolution, 36(6), 1254–1269. https://doi.org/10.1093/molbev/msz066Michdakis, Y., & Excoffied, L. (1996). A Generic Estimation of Population Subdivision Using Distances Between Alleles With Special Reference for Microsatellite Loci. http://acasunl.unige.ch/LGB/Moncada Madero, J. A. (2018). Análisis de la estructura genética de una muestra de población del departamento de Amazonas, Colombia.Moreno-Mayar, J. V., Vinner, L., de Barros Damgaard, P., de La Fuente, C., Chan, J., Spence, J. P., Allentoft, M. E., Vimala, T., Racimo, F., Pinotti, T., Rasmussen, S., Margaryan, A., Orbegozo, M. I., Mylopotamitaki, D., Wooller, M., Bataille, C., Becerra-Valdivia, L., Chivall, D., Comeskey, D., … Willerslev, E. (2018). Early human dispersals within the Americas. Science, 362(6419). https://doi.org/10.1126/science.aav2621Ossa, H., Aquino, J., Pereira, R., Ibarra, A., Ossa, R. 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The social conquest of Earth (Vol. 50). https://doi.org/10.5860/CHOICE.50-2648EstudiantesLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unal.edu.co/bitstream/unal/82064/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINAL1121900379.2022.pdf1121900379.2022.pdfTesis de Maestría en Genética Humanaapplication/pdf2280089https://repositorio.unal.edu.co/bitstream/unal/82064/3/1121900379.2022.pdf19df74180b372b46e6fac976ec1f99aaMD53THUMBNAIL1121900379.2022.pdf.jpg1121900379.2022.pdf.jpgGenerated Thumbnailimage/jpeg4350https://repositorio.unal.edu.co/bitstream/unal/82064/4/1121900379.2022.pdf.jpg97e0849a762e30df3929f777834cff44MD54unal/82064oai:repositorio.unal.edu.co:unal/820642024-08-09 23:20:45.299Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.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