Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos
Zymomonas Mobilis (Z. Mobilis), are fermenting microorganisms that under anaerobic conditions transform reducing sugars into ethyl alcohol. Although to date, mathematical models based on mass transfer have been proposed that suggest the representation of phenomena associated with the growth of micro...
- Autores:
-
Pulido Aponte, Álvaro Ervey
- Tipo de recurso:
- Work document
- Fecha de publicación:
- 2020
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
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- spa
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- oai:repositorio.unal.edu.co:unal/77901
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- https://repositorio.unal.edu.co/handle/unal/77901
- Palabra clave:
- 620 - Ingeniería y operaciones afines
660 - Ingeniería química
Z.Mobilis
quimiostato
competencia
coexistencia
modelamiento
teoría de juegos
chemostat
competition
coexistence
growth
concentration
game theory
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Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos |
| title |
Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos |
| spellingShingle |
Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos 620 - Ingeniería y operaciones afines 660 - Ingeniería química Z.Mobilis quimiostato competencia coexistencia modelamiento teoría de juegos chemostat competition coexistence growth concentration game theory |
| title_short |
Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos |
| title_full |
Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos |
| title_fullStr |
Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos |
| title_full_unstemmed |
Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos |
| title_sort |
Dinámica de Crecimiento y Competencia para Zymomonas Mobilis: una aproximación desde un modelo co-evolutivo basado en teoría de juegos |
| dc.creator.fl_str_mv |
Pulido Aponte, Álvaro Ervey |
| dc.contributor.advisor.spa.fl_str_mv |
Mojica Nava, Eduardo Alirio Rivera Escobar, Hernán Mauricio |
| dc.contributor.author.spa.fl_str_mv |
Pulido Aponte, Álvaro Ervey |
| dc.contributor.corporatename.spa.fl_str_mv |
Universidad Nacional de Colombia |
| dc.subject.ddc.spa.fl_str_mv |
620 - Ingeniería y operaciones afines 660 - Ingeniería química |
| topic |
620 - Ingeniería y operaciones afines 660 - Ingeniería química Z.Mobilis quimiostato competencia coexistencia modelamiento teoría de juegos chemostat competition coexistence growth concentration game theory |
| dc.subject.proposal.spa.fl_str_mv |
Z.Mobilis quimiostato competencia coexistencia modelamiento teoría de juegos |
| dc.subject.proposal.eng.fl_str_mv |
chemostat competition coexistence growth concentration game theory |
| description |
Zymomonas Mobilis (Z. Mobilis), are fermenting microorganisms that under anaerobic conditions transform reducing sugars into ethyl alcohol. Although to date, mathematical models based on mass transfer have been proposed that suggest the representation of phenomena associated with the growth of microbial populations, little is known about their implementation for specific cases in which the evidence is purely experimental, such as a case of the dynamics expressed by two strains of (Z. Mobilis) in the same confinement space. The objective of this thesis was to evaluate in silico the dynamics of growth and competition of two strains of the organism Zymomonas Mobilis in a fermentative process. For this, a multi-population mathematical model based on the chemostat mass transfer was represented for a fermentation process called model A, its implementation for two strains of Z. Mobilis (ZM1 and ZM4) and the possible implications for stability and process control. On the other hand, a co-evolutionary model based on an evolutionary game theory called model B was obtained, from the use of strategies adopted by the same competing strains; The criteria for selecting the strategies included growth kinetics and substrate consumption for the fermentation process. Finally, two strategies were implemented for the design of a proportional, integral, and derivative controller, the first empirical by the Ziegler-Nichols method and the second by the virtual reference feedback tuning method. In contrast to the values obtained an independent culture for ZM1 and ZM4, in competition, the results were incremental for ZM4 in terms of generation of microbial biomass and product in model A. Compared to model B, the extinction of ZM1 was evidenced by cause of the strategies adopted by ZM4. A comparative table was made showing the main advantages and disadvantages of the two proposed models. |
| publishDate |
2020 |
| dc.date.accessioned.spa.fl_str_mv |
2020-08-03T20:46:12Z |
| dc.date.available.spa.fl_str_mv |
2020-08-03T20:46:12Z |
| dc.date.issued.spa.fl_str_mv |
2020-06-16 |
| dc.type.spa.fl_str_mv |
Documento de trabajo |
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info:eu-repo/semantics/workingPaper |
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info:eu-repo/semantics/acceptedVersion |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_8042 |
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Text |
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http://purl.org/redcol/resource_type/WP |
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http://purl.org/coar/resource_type/c_8042 |
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acceptedVersion |
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https://repositorio.unal.edu.co/handle/unal/77901 |
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https://repositorio.unal.edu.co/handle/unal/77901 |
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spa |
| language |
spa |
| dc.relation.references.spa.fl_str_mv |
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Atribución-NoComercial-SinDerivadas 4.0 InternacionalDerechos reservados - Universidad Nacional de ColombiaAcceso abiertohttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Mojica Nava, Eduardo Alirio050d6ad9-99b6-40d6-a22a-47bd4afc1ead-1Rivera Escobar, Hernán Mauricio3d1261aa-89b7-452d-a75b-1e05bf1081b7-1Pulido Aponte, Álvaro Ervey76754848-c381-4fc2-9d3b-f5212a8baf4fUniversidad Nacional de Colombia2020-08-03T20:46:12Z2020-08-03T20:46:12Z2020-06-16https://repositorio.unal.edu.co/handle/unal/77901Zymomonas Mobilis (Z. Mobilis), are fermenting microorganisms that under anaerobic conditions transform reducing sugars into ethyl alcohol. Although to date, mathematical models based on mass transfer have been proposed that suggest the representation of phenomena associated with the growth of microbial populations, little is known about their implementation for specific cases in which the evidence is purely experimental, such as a case of the dynamics expressed by two strains of (Z. Mobilis) in the same confinement space. The objective of this thesis was to evaluate in silico the dynamics of growth and competition of two strains of the organism Zymomonas Mobilis in a fermentative process. For this, a multi-population mathematical model based on the chemostat mass transfer was represented for a fermentation process called model A, its implementation for two strains of Z. Mobilis (ZM1 and ZM4) and the possible implications for stability and process control. On the other hand, a co-evolutionary model based on an evolutionary game theory called model B was obtained, from the use of strategies adopted by the same competing strains; The criteria for selecting the strategies included growth kinetics and substrate consumption for the fermentation process. Finally, two strategies were implemented for the design of a proportional, integral, and derivative controller, the first empirical by the Ziegler-Nichols method and the second by the virtual reference feedback tuning method. In contrast to the values obtained an independent culture for ZM1 and ZM4, in competition, the results were incremental for ZM4 in terms of generation of microbial biomass and product in model A. Compared to model B, the extinction of ZM1 was evidenced by cause of the strategies adopted by ZM4. A comparative table was made showing the main advantages and disadvantages of the two proposed models.Zymomonas Mobilis (Z. Mobilis), son microorganismos fermentadores que bajo condiciones anaeróbicas transforman los azucares reductores en alcohol etílico. Aunque a la fecha se han planteado modelos matemáticos basados en transferencia de masa que sugieren la representación de fenómenos asociados al crecimiento de poblaciones microbianas, poco se sabe en cuanto a su implementación para casos específicos en los que la evidencia es netamente experimental, como es el caso de la dinámica expresada por dos cepas de (Z. Mobilis) en el mismo espacio de con finamiento. El objetivo de esta tesis fue evaluar in silico la dinámica del crecimiento y competencia de dos cepas del organismo Zymomonas Mobilis en un proceso fermentativo. Para ello, se representó un modelo matemático multipoblacional basado en la transferencia de masa del quimiostato para un proceso fermentativo denominado modelo A, su implementación para dos cepas de Z. Mobilis (ZM1 y ZM4) y las posibles implicaciones en la estabilidad y el control del proceso. Por otro lado, se obtuvo un modelo co-evolutivo basado en teoría de juegos evolutivos denominado modelo B, desde el uso de estrategias adoptadas por las mismas cepas en competencia; el criterio de selección de las estrategias incluyó la cinética de crecimiento y el consumo de sustrato para el proceso de fermentación. Finalmente, se implementaron dos estrategias para el diseño de un controlador proporcional, integral y derivativo, la primera empírica por el método de Ziegler-Nichols y la segunda por el método de ajuste de realimentación por referencia virtual. A diferencia de los valores obtenidos en cultivo independiente para ZM1 y ZM4, en competencia, los resultados fueron incrementales para ZM4 en términos de generación de biomasa microbiana y producto en el modelo A. Frente al modelo B, se evidenció la extinción de ZM1 a causa de las estrategias adoptadas por ZM4. 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Zeeman, "Extinction in competitive lotka-volterra systems," Proceedings of the American Mathematical Society, vol. 123, no. 1, pp. 87-96, 1995.ORIGINAL1024508293.2020.pdf1024508293.2020.pdfapplication/pdf8117265https://repositorio.unal.edu.co/bitstream/unal/77901/1/1024508293.2020.pdfb895825144f720643aafbbc3bda969c5MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-83991https://repositorio.unal.edu.co/bitstream/unal/77901/2/license.txt6f3f13b02594d02ad110b3ad534cd5dfMD52CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8811https://repositorio.unal.edu.co/bitstream/unal/77901/3/license_rdf217700a34da79ed616c2feb68d4c5e06MD53THUMBNAIL1024508293.2020.pdf.jpg1024508293.2020.pdf.jpgGenerated Thumbnailimage/jpeg4986https://repositorio.unal.edu.co/bitstream/unal/77901/4/1024508293.2020.pdf.jpg7eba0a61d33a121ec9d045fa969101f7MD54unal/77901oai:repositorio.unal.edu.co:unal/779012024-07-20 23:11:36.512Repositorio Institucional Universidad Nacional de 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