Synthesis, characterization and antibacterial screening of some Schiff bases derived from pyrazole and 4-amino antipyrine

Some Schiff bases of pyrazole and 4-amino antipyrine have been synthesized. The antibacterial screening of these synthesized compounds was done in dimethyl forma-mide against four Gram positive bacteria viz. Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidids and Micrococcus luteus,...

Full description

Autores:
Baluja, Shipra
Chanda, Sumitra
Tipo de recurso:
Article of journal
Fecha de publicación:
2016
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/66605
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/66605
http://bdigital.unal.edu.co/67633/
Palabra clave:
66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
Pyrazole
4-amino antipyrine
Schiff bases
dimethyl formamide
antibacterial activity
Pirazol
4-amino antipirina
bases de Schiff
dimetil formamida
actividad antibacteriana
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
Description
Summary:Some Schiff bases of pyrazole and 4-amino antipyrine have been synthesized. The antibacterial screening of these synthesized compounds was done in dimethyl forma-mide against four Gram positive bacteria viz. Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidids and Micrococcus luteus, and three Gram negative bacteria viz. Proteus mirabilis, Escherichia coli and Klebsiella aerogenes. It is observed that in comparison to Schiff bases of 4-amino antipyrine, pyrazole Schiff bases are better for inhibition for these selected Gram positive and Gram negative bacterial strains.