1-Octanol-water partition coefficient of some cyanopyridine and chalcone compounds

The partition coefficients (P) of some synthesized cyanopyridine and chalcone compounds have been studied in 1-octanol-water system at different pH. It is observed that log P depends on pH and nature of substitution group present in the compounds. The central moiety also play important role to affec...

Full description

Autores:
Baluja, Shipra
Kulshrestha, Anchal
Movalia, Jagdish
Tipo de recurso:
Article of journal
Fecha de publicación:
2017
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/66578
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/66578
http://bdigital.unal.edu.co/67606/
Palabra clave:
66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
coeficiente de reparto
cianopiridinas
chalconas
sistema 1-octanolagua
partition coefficient
cyanopyridines
chalcones
1-octanol-water system
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
Description
Summary:The partition coefficients (P) of some synthesized cyanopyridine and chalcone compounds have been studied in 1-octanol-water system at different pH. It is observed that log P depends on pH and nature of substitution group present in the compounds. The central moiety also play important role to affect hydrophilic/hydrophobic nature of compounds. There is no regular trend for the variation of log P with different pH.