Potential of optical waveguide structures to measure the chirality parameter of chiral substances

ilustraciones

Autores:: Enríquez Espinoza, Jim Alexander

Tipo de recurso:

Fecha de publicación:: 2021

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: eng

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network_acronym_str	UNACIONAL2
network_name_str	Universidad Nacional de Colombia
repository_id_str
dc.title.eng.fl_str_mv	Potential of optical waveguide structures to measure the chirality parameter of chiral substances
dc.title.translated.spa.fl_str_mv	Potencial de las estructuras de guía de ondas ópticas para medir el parámetro de quiralidad de sustancias quirales
title	Potential of optical waveguide structures to measure the chirality parameter of chiral substances
spellingShingle	Potential of optical waveguide structures to measure the chirality parameter of chiral substances 530 - Física 620 - Ingeniería y operaciones afines Guías de ondas ópticas Chirality parameter Chiral substances Dispersion curves Enantiomeric content Guided modes Polarization Optical waveguide Sensor Parámetro de quiralidad Sustancias quirales Curvas de dispersión Contenido enantiomérico Modos guiados Polarización Guía de onda óptica
title_short	Potential of optical waveguide structures to measure the chirality parameter of chiral substances
title_full	Potential of optical waveguide structures to measure the chirality parameter of chiral substances
title_fullStr	Potential of optical waveguide structures to measure the chirality parameter of chiral substances
title_full_unstemmed	Potential of optical waveguide structures to measure the chirality parameter of chiral substances
title_sort	Potential of optical waveguide structures to measure the chirality parameter of chiral substances
dc.creator.fl_str_mv	Enríquez Espinoza, Jim Alexander
dc.contributor.advisor.none.fl_str_mv	Torres Trujillo, Pedro Ignacio
dc.contributor.author.none.fl_str_mv	Enríquez Espinoza, Jim Alexander
dc.contributor.researchgroup.spa.fl_str_mv	Fotónica y Optoelectrónica
dc.subject.ddc.spa.fl_str_mv	530 - Física 620 - Ingeniería y operaciones afines
topic	530 - Física 620 - Ingeniería y operaciones afines Guías de ondas ópticas Chirality parameter Chiral substances Dispersion curves Enantiomeric content Guided modes Polarization Optical waveguide Sensor Parámetro de quiralidad Sustancias quirales Curvas de dispersión Contenido enantiomérico Modos guiados Polarización Guía de onda óptica
dc.subject.lemb.none.fl_str_mv	Guías de ondas ópticas
dc.subject.proposal.eng.fl_str_mv	Chirality parameter Chiral substances Dispersion curves Enantiomeric content Guided modes Polarization Optical waveguide
dc.subject.proposal.none.fl_str_mv	Sensor
dc.subject.proposal.spa.fl_str_mv	Parámetro de quiralidad Sustancias quirales Curvas de dispersión Contenido enantiomérico Modos guiados Polarización Guía de onda óptica
description	ilustraciones
publishDate	2021
dc.date.accessioned.none.fl_str_mv	2021-06-21T19:54:19Z
dc.date.available.none.fl_str_mv	2021-06-21T19:54:19Z
dc.date.issued.none.fl_str_mv	2021-02-18
dc.type.spa.fl_str_mv	Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv	Text
dc.type.redcol.spa.fl_str_mv	http://purl.org/redcol/resource_type/TM
status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/79660
dc.identifier.instname.spa.fl_str_mv	Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv	https://repositorio.unal.edu.co/
url	https://repositorio.unal.edu.co/handle/unal/79660 https://repositorio.unal.edu.co/
identifier_str_mv	Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv	eng
language	eng
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dc.rights.license.spa.fl_str_mv	Atribución-NoComercial-SinDerivadas 4.0 Internacional
dc.rights.uri.spa.fl_str_mv	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.accessrights.spa.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	Atribución-NoComercial-SinDerivadas 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2
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dc.format.extent.spa.fl_str_mv	125 páginas
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dc.publisher.spa.fl_str_mv	Universidad Nacional de Colombia
dc.publisher.program.spa.fl_str_mv	Medellín - Ciencias - Maestría en Ciencias - Física
dc.publisher.department.spa.fl_str_mv	Escuela de física
dc.publisher.faculty.spa.fl_str_mv	Facultad de Ciencias
dc.publisher.place.spa.fl_str_mv	Medellín
dc.publisher.branch.spa.fl_str_mv	Universidad Nacional de Colombia - Sede Medellín
institution	Universidad Nacional de Colombia
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spelling	Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Torres Trujillo, Pedro Ignacioe15bd4856b7b8afb46d688ce14cfc3ee600Enríquez Espinoza, Jim Alexander539cfe60cfafcf740784038d3d4b6aeaFotónica y Optoelectrónica2021-06-21T19:54:19Z2021-06-21T19:54:19Z2021-02-18https://repositorio.unal.edu.co/handle/unal/79660Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustracionesThe chiral molecule interactions depend on their chirality. Important molecules of life such as proteins, enzymes, amino acids, carbohydrates, and so on, are chiral. Chiral substances which interact with them, such as drugs and agrochemicals, must present a specific enantiomeric content to assure effectiveness. Thus, whereas one enantiomer of a chiral drug or agrochemical product has a desired effect, the other one may be inactive or even toxic. The study of methods to identify the enantiomeric content of chiral substances is a current research topic. Although there are a wide variety of methods, which generally demand expensive reagents, large equipment, and the need for highly qualified personnel, new techniques are still in demand due to the continuous development of new chiral substances, and the industrial need to perform millions of tests during short periods of time. In this scenary, methods based on optical waveguide structures present a great potential, providing great sensitivity, real-time monitoring, and no invasiveness. For this reason, in this M.Sc. thesis, a theoretical and numerical study of optical waveguides involving chiral media is presented. The study is centered around planar symmetric and asymmetric waveguides, where the effects of the real, and for the first time, the imaginary part of the chirality parameter are analyzed in the characteristics of the guided light. As an application of the study, a lossy mode resonances (LMR) based optical fiber sensor is designed to measure the chirality parameter. (Tomado de la fuente)Las interacciones de moléculas quirales dependen de su quiralidad. Las moléculas importantes para la vida como proteínas, enzimas, aminoácidos, carbohidratos, etc., son quirales. Las sustancias quirales que interactúan con ellas, como fármacos y agroquímicos, deben poseer un contenido enantiomérico específico para asegurar su efectividad. De esta manera, mientras un enantiómero de un fármaco quiral o un agroquímico quiral produce los efectos deseados, el otro podría ser inactivo o incluso tóxico. El estudio de los métodos para identificar el contenido enantiomérico de sustancias quirales es un área de investigación actual. A pesar de que hay una amplia variedad de métodos, los cuales generalmente demandan reactivos caros, equipos de gran tamaño y la necesidad de personal altamente calificado, se demandan nuevas técnicas debido al continuo desarrollo de sustancias quirales y la necesidad industrial de llevar a cabo millones de pruebas en cortos periodos de tiempo. En este escenario, los métodos basados en guías de onda ópticas presentan un gran potencial, ofreciendo gran sensibilidad, monitoreo en tiempo real y no invasibidad. Por esta razón, en esta tesis de maestría en ciencias se presenta un estudio teórico y numérico de guías de onda óptica con medios quirales. El estudio se centra en guías de onda planas simétricas y asimétricas, donde se analizan los efectos de la parte real, y por primera vez, la parte imaginaria del parámetro de quiralidad sobre la luz guiada. Como una aplicación del estudio, se diseña un sensor basado en resonancias de modos con pérdidas en fibra óptica para medir el parámetro de quiralidad. (Tomado de la fuente)MaestríaMagíster en Ciencias - FísicaFotónica125 páginasapplication/pdfengUniversidad Nacional de ColombiaMedellín - Ciencias - Maestría en Ciencias - FísicaEscuela de físicaFacultad de CienciasMedellínUniversidad Nacional de Colombia - Sede Medellín530 - Física620 - Ingeniería y operaciones afinesGuías de ondas ópticasChirality parameterChiral substancesDispersion curvesEnantiomeric contentGuided modesPolarizationOptical waveguideSensorParámetro de quiralidadSustancias quiralesCurvas de dispersiónContenido enantioméricoModos guiadosPolarizaciónGuía de onda ópticaPotential of optical waveguide structures to measure the chirality parameter of chiral substancesPotencial de las estructuras de guía de ondas ópticas para medir el parámetro de quiralidad de sustancias quiralesTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TM[1] Nallamuthu Ananthi. Role of Chirality in Drugs. 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Chiral slab: COMSOL simulation. Unpublished paper, 2017.EspecializadaLICENSElicense.txtlicense.txttext/plain; charset=utf-83964https://repositorio.unal.edu.co/bitstream/unal/79660/1/license.txtcccfe52f796b7c63423298c2d3365fc6MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://repositorio.unal.edu.co/bitstream/unal/79660/3/license_rdf4460e5956bc1d1639be9ae6146a50347MD53ORIGINAL1085321420.2021.pdf1085321420.2021.pdfTesis Maestría en Ciencias - Físicaapplication/pdf10903242https://repositorio.unal.edu.co/bitstream/unal/79660/4/1085321420.2021.pdf9e5e2cd727130ebbe4029b547d06d941MD54THUMBNAIL1085321420.2021.pdf.jpg1085321420.2021.pdf.jpgGenerated Thumbnailimage/jpeg4557https://repositorio.unal.edu.co/bitstream/unal/79660/5/1085321420.2021.pdf.jpg5efe718b65c277dfa09e0bb31f8453afMD55unal/79660oai:repositorio.unal.edu.co:unal/796602024-07-22 23:40:03.471Repositorio Institucional Universidad Nacional de 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GVyZWNob3MgZGUgYXV0b3IgcXVlIGNvbmxsZXZlIGxhIGRpc3RyaWJ1Y2nDs24gZGUgZXN0b3MgYXJjaGl2b3MgeSBtZXRhZGF0b3MuCkFsIGhhY2VyIGNsaWMgZW4gZWwgc2lndWllbnRlIGJvdMOzbiwgdXN0ZWQgaW5kaWNhIHF1ZSBlc3TDoSBkZSBhY3VlcmRvIGNvbiBlc3RvcyB0w6lybWlub3MuCgpVTklWRVJTSURBRCBOQUNJT05BTCBERSBDT0xPTUJJQSAtIMOabHRpbWEgbW9kaWZpY2FjacOzbiAyNy8yMC8yMDIwCg==

Potential of optical waveguide structures to measure the chirality parameter of chiral substances

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