Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast

Cordia dendata Poir, Heliotropium indicum Linn and Momordica charantia Linn areused for treatment of the most common human diseases and health disorders in folkmedicine of the population from the northern Colombian coast. In this study, chemicalcomposition and antibacterial activity of the ethanol e...

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Autores:
Cervantes Ceballos, Leonor
Sánchez Hoyos, Fredys
Gómez Estrada, Harold
Tipo de recurso:
Article of journal
Fecha de publicación:
2017
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/66582
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/66582
http://bdigital.unal.edu.co/67610/
Palabra clave:
66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
actividad antibacterial
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
Antibacterial activity
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
id UNACIONAL2_15ad1d49aa93b266bdeda24b22d618d4
oai_identifier_str oai:repositorio.unal.edu.co:unal/66582
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast
title Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast
spellingShingle Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast
66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
actividad antibacterial
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
Antibacterial activity
title_short Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast
title_full Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast
title_fullStr Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast
title_full_unstemmed Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast
title_sort Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast
dc.creator.fl_str_mv Cervantes Ceballos, Leonor
Sánchez Hoyos, Fredys
Gómez Estrada, Harold
dc.contributor.author.spa.fl_str_mv Cervantes Ceballos, Leonor
Sánchez Hoyos, Fredys
Gómez Estrada, Harold
dc.subject.ddc.spa.fl_str_mv 66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
topic 66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
actividad antibacterial
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
Antibacterial activity
dc.subject.proposal.spa.fl_str_mv Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
actividad antibacterial
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
Antibacterial activity
description Cordia dendata Poir, Heliotropium indicum Linn and Momordica charantia Linn areused for treatment of the most common human diseases and health disorders in folkmedicine of the population from the northern Colombian coast. In this study, chemicalcomposition and antibacterial activity of the ethanol extract and fractions fromC. dentata, H. indicum and M. charantia were investigated. The chemical constituentsof qualitative detection were examined by Thin Layer Chromatography (TLC).The antibacterial activity was determined by agar gel diffusion and broth microdilutionmethod. The main identified compounds were flavonoids, cardiac glycosides,alkaloids, saponins, terpenoids, tannins and coumarins. The minimal inhibitoryconcentration (MIC) was 31.25 to 1000 g/mL for Gram-positive and Gram-negativebacteria, respectively. These results indicated that ethanol extract and fractionsfrom C. dentata, H. indicum and M. charantia significantly inhibited the growthof standard strains. Potent antibacterial activities of C. dentata, H. indicum and M.charantia may be considered in future study, particularly against antibiotic-resistantcases.
publishDate 2017
dc.date.issued.spa.fl_str_mv 2017-05-01
dc.date.accessioned.spa.fl_str_mv 2019-07-03T02:25:13Z
dc.date.available.spa.fl_str_mv 2019-07-03T02:25:13Z
dc.type.spa.fl_str_mv Artículo de revista
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.issn.spa.fl_str_mv ISSN: 1909-6356
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/66582
dc.identifier.eprints.spa.fl_str_mv http://bdigital.unal.edu.co/67610/
identifier_str_mv ISSN: 1909-6356
url https://repositorio.unal.edu.co/handle/unal/66582
http://bdigital.unal.edu.co/67610/
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.spa.fl_str_mv https://revistas.unal.edu.co/index.php/rccquifa/article/view/67933
dc.relation.ispartof.spa.fl_str_mv Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico Farmacéuticas
Revista Colombiana de Ciencias Químico Farmacéuticas
dc.relation.references.spa.fl_str_mv Cervantes Ceballos, Leonor and Sánchez Hoyos, Fredys and Gómez Estrada, Harold (2017) Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast. Revista Colombiana de Ciencias Químico-Farmacéuticas, 46 (2). pp. 143-159. ISSN 1909-6356
dc.rights.spa.fl_str_mv Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.spa.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
Derechos reservados - Universidad Nacional de Colombia
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia - Sede Bogotá - Facultad de Ciencias - Departamento de Farmacia
institution Universidad Nacional de Colombia
bitstream.url.fl_str_mv https://repositorio.unal.edu.co/bitstream/unal/66582/1/67933-365104-1-PB.pdf
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repository.name.fl_str_mv Repositorio Institucional Universidad Nacional de Colombia
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spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Cervantes Ceballos, Leonor7b98c759-d78a-48e9-82b3-ece387a45313300Sánchez Hoyos, Fredysd767378b-dd17-462f-947d-3f5e91663b7e300Gómez Estrada, Harold4479004e-cc7c-4922-9dbf-90ceb74483943002019-07-03T02:25:13Z2019-07-03T02:25:13Z2017-05-01ISSN: 1909-6356https://repositorio.unal.edu.co/handle/unal/66582http://bdigital.unal.edu.co/67610/Cordia dendata Poir, Heliotropium indicum Linn and Momordica charantia Linn areused for treatment of the most common human diseases and health disorders in folkmedicine of the population from the northern Colombian coast. In this study, chemicalcomposition and antibacterial activity of the ethanol extract and fractions fromC. dentata, H. indicum and M. charantia were investigated. The chemical constituentsof qualitative detection were examined by Thin Layer Chromatography (TLC).The antibacterial activity was determined by agar gel diffusion and broth microdilutionmethod. The main identified compounds were flavonoids, cardiac glycosides,alkaloids, saponins, terpenoids, tannins and coumarins. The minimal inhibitoryconcentration (MIC) was 31.25 to 1000 g/mL for Gram-positive and Gram-negativebacteria, respectively. These results indicated that ethanol extract and fractionsfrom C. dentata, H. indicum and M. charantia significantly inhibited the growthof standard strains. Potent antibacterial activities of C. dentata, H. indicum and M.charantia may be considered in future study, particularly against antibiotic-resistantcases.Cordia dendata Poir, Heliotropium indicum Linn y Momordica charantia Linn sonusadas para el tratamiento de las enfermedades más comunes y trastornos de salud enla medicina popular de la población de la costa norte de Colombia. En este estudiose investigó la composición química y la actividad antibacterial de los extractosetanólicos y fracciones de C. dentata, H. indicum y M. charantia. Los constituyentesquímicos se examinaron por detección cualitativa cromatografía de capa fina (TLC,por sus siglas en inglés). La actividad antibacterial se determinó por difusión en agary microdilución en caldo. Los mayores compuestos identificados fueron flavonoides,glucósidos cardiotónicos, alcaloides, saponinas, terpenoides, taninos y cumarinas.La concentración inhibitoria mínima (MIC, por sus siglas en inglés) fue de 31,25a 1.000 g/mL para bacterias Gram-positivas y Gram-negativas, respectivamente.Estos resultados indican que el extracto etanólico y las fracciones de C. dentata, H.indicum y M. charantia inhibieron de manera significa el crecimiento de las cepasestándar. La potente actividad antibacterial de C. dentata, H. indicum y M. charantiapuede considerarse en posteriores estudios, en particular frente a casos de antibióticosresistentes.application/pdfspaUniversidad Nacional de Colombia - Sede Bogotá - Facultad de Ciencias - Departamento de Farmaciahttps://revistas.unal.edu.co/index.php/rccquifa/article/view/67933Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico FarmacéuticasRevista Colombiana de Ciencias Químico FarmacéuticasCervantes Ceballos, Leonor and Sánchez Hoyos, Fredys and Gómez Estrada, Harold (2017) Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast. Revista Colombiana de Ciencias Químico-Farmacéuticas, 46 (2). pp. 143-159. ISSN 1909-635666 Ingeniería química y Tecnologías relacionadas/ Chemical engineering61 Ciencias médicas; Medicina / Medicine and healthCordia dendata PoirHeliotropium indicum LinnMomordica charantia Linnactividad antibacterialCordia dendata PoirHeliotropium indicum LinnMomordica charantia LinnAntibacterial activityAntibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian CoastArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTORIGINAL67933-365104-1-PB.pdfapplication/pdf1013663https://repositorio.unal.edu.co/bitstream/unal/66582/1/67933-365104-1-PB.pdf3e9cee397d56b042656fd1f068b12343MD51THUMBNAIL67933-365104-1-PB.pdf.jpg67933-365104-1-PB.pdf.jpgGenerated Thumbnailimage/jpeg5964https://repositorio.unal.edu.co/bitstream/unal/66582/2/67933-365104-1-PB.pdf.jpg234390b84fe3300718eab91bc9de6bfaMD52unal/66582oai:repositorio.unal.edu.co:unal/665822023-05-25 23:03:15.741Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co

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