Antibacterial activity of Cordia dentata Poir, Heliotropium indicum Linn and Momordica charantia Linn from the Northern Colombian Coast

Cordia dendata Poir, Heliotropium indicum Linn and Momordica charantia Linn areused for treatment of the most common human diseases and health disorders in folkmedicine of the population from the northern Colombian coast. In this study, chemicalcomposition and antibacterial activity of the ethanol e...

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Autores:
Cervantes Ceballos, Leonor
Sánchez Hoyos, Fredys
Gómez Estrada, Harold
Tipo de recurso:
Article of journal
Fecha de publicación:
2017
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/66582
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/66582
http://bdigital.unal.edu.co/67610/
Palabra clave:
66 Ingeniería química y Tecnologías relacionadas/ Chemical engineering
61 Ciencias médicas; Medicina / Medicine and health
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
actividad antibacterial
Cordia dendata Poir
Heliotropium indicum Linn
Momordica charantia Linn
Antibacterial activity
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
Description
Summary:Cordia dendata Poir, Heliotropium indicum Linn and Momordica charantia Linn areused for treatment of the most common human diseases and health disorders in folkmedicine of the population from the northern Colombian coast. In this study, chemicalcomposition and antibacterial activity of the ethanol extract and fractions fromC. dentata, H. indicum and M. charantia were investigated. The chemical constituentsof qualitative detection were examined by Thin Layer Chromatography (TLC).The antibacterial activity was determined by agar gel diffusion and broth microdilutionmethod. The main identified compounds were flavonoids, cardiac glycosides,alkaloids, saponins, terpenoids, tannins and coumarins. The minimal inhibitoryconcentration (MIC) was 31.25 to 1000 g/mL for Gram-positive and Gram-negativebacteria, respectively. These results indicated that ethanol extract and fractionsfrom C. dentata, H. indicum and M. charantia significantly inhibited the growthof standard strains. Potent antibacterial activities of C. dentata, H. indicum and M.charantia may be considered in future study, particularly against antibiotic-resistantcases.