Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity

In this work, the effect of aqueous and methanolic extracts of the plants species Critoniella acuminata, Salvia rubescens, Phenax rugosus (Poir.) Wedd and Tabebuia chrysanta G. on the enzymes elastase and myeloperoxidase, involved in degranulation leukocyte process, was evaluated, identifying the po...

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Autores:
Cárdenas, Paola Andrea
Aragón, Diana Marcela
Ospina, Luis Fernando
Isaza, Gustavo
Pérez, Jorge Enrique
Tipo de recurso:
Article of journal
Fecha de publicación:
2012
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/49311
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/49311
http://bdigital.unal.edu.co/42768/
http://bdigital.unal.edu.co/42768/2/
Palabra clave:
Critoniella acuminata
desgranulación
elastasa
mieloperoxidasa
Phenax rugosus
Salvia rubescens
Tabebuia chrysanta
Critoniella acuminata
degranulation
elastase
myeloperoxidase
Phenax rugosus
Salvia rubescens
Tabebuia chrysanta
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
id UNACIONAL2_150f0495a0d93cf419eb1057921cd508
oai_identifier_str oai:repositorio.unal.edu.co:unal/49311
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Cárdenas, Paola Andrea2a5186fe-bfd6-4f24-bca3-fed98643c6cd300Aragón, Diana Marcelac32b9fcd-a138-4fc1-8ed1-b754df983335300Ospina, Luis Fernando38bb8be2-6cdb-4809-8501-9f276e5e6234300Isaza, Gustavo7b10d032-d82b-4461-ac54-8896529528b9300Pérez, Jorge Enriquef5ba71ec-d09e-470d-bab1-3edc61ea1e883002019-06-29T08:34:45Z2019-06-29T08:34:45Z2012https://repositorio.unal.edu.co/handle/unal/49311http://bdigital.unal.edu.co/42768/http://bdigital.unal.edu.co/42768/2/In this work, the effect of aqueous and methanolic extracts of the plants species Critoniella acuminata, Salvia rubescens, Phenax rugosus (Poir.) Wedd and Tabebuia chrysanta G. on the enzymes elastase and myeloperoxidase, involved in degranulation leukocyte process, was evaluated, identifying the potential direct inhibitory effect on the enzyme and/or inhibition of the desgranulation of polymorphonuclear neutrophils. Extracts of Critoniella acuminata andSalvia rubescens presented effects on the degranulation process and the inhibition of the enzyme elastase and myeloperoxidase; the extracts of Phenax rugosus do not showed significant effect. Tabebuia chrysanta methanolic extract only showed effect on inhibition of elastase activity.Se evaluó el efecto de extractos metanólicos y acuosos de las especies vegetales Critoniella acuminata, Salvia rubescens, Phenax rugosus (Poir.) Wedd y Tabebuia chrysanta G. Nicholson sobre las enzimas elastasa y mieloperoxidasa, relacionadas con el proceso de desgranulación leucocitaria, y se determinó el potencial efecto inhibitorio directo sobre la enzima o la inhibición de la desgranulación de los neutrófilos polimorfonucleares. Los extractos de Critoniella acuminata y Salvia rubescens presentaron efectos sobre el proceso de desgranulación y la actividad de las enzimas mieloperoxidasa y elastasa; en el caso de los extractos de Phenax rugosus, estos no mostraron un efecto significativo sobre ninguna de las enzimas. De la especieTabebuia chrysanta solamente el extracto metanólico mostró efecto sobre la inhibición de la actividad elastasa.application/pdfspaRevista Colombiana de Ciencias Químico Farmacéuticashttp://revistas.unal.edu.co/index.php/rccquifa/article/view/45094Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico FarmacéuticasRevista Colombiana de Ciencias Químico FarmacéuticasRevista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 2 (2012); 157-166 0034-7418 1909-6356Cárdenas, Paola Andrea and Aragón, Diana Marcela and Ospina, Luis Fernando and Isaza, Gustavo and Pérez, Jorge Enrique (2012) Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity. Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 2 (2012); 157-166 0034-7418 1909-6356 .Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activityArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTCritoniella acuminatadesgranulaciónelastasamieloperoxidasaPhenax rugosusSalvia rubescensTabebuia chrysantaCritoniella acuminatadegranulationelastasemyeloperoxidasePhenax rugosusSalvia rubescensTabebuia chrysantaORIGINAL45094-216205-1-SM.pdfapplication/pdf102798https://repositorio.unal.edu.co/bitstream/unal/49311/1/45094-216205-1-SM.pdf9b1cc7aad0d997c4a7eb4ecb3d16e4feMD51THUMBNAIL45094-216205-1-SM.pdf.jpg45094-216205-1-SM.pdf.jpgGenerated Thumbnailimage/jpeg6456https://repositorio.unal.edu.co/bitstream/unal/49311/2/45094-216205-1-SM.pdf.jpgf52df0e2c643cbf60fb4ffa64e71953aMD52unal/49311oai:repositorio.unal.edu.co:unal/493112023-12-09 23:05:55.408Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co
dc.title.spa.fl_str_mv Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity
title Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity
spellingShingle Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity
Critoniella acuminata
desgranulación
elastasa
mieloperoxidasa
Phenax rugosus
Salvia rubescens
Tabebuia chrysanta
Critoniella acuminata
degranulation
elastase
myeloperoxidase
Phenax rugosus
Salvia rubescens
Tabebuia chrysanta
title_short Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity
title_full Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity
title_fullStr Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity
title_full_unstemmed Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity
title_sort Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity
dc.creator.fl_str_mv Cárdenas, Paola Andrea
Aragón, Diana Marcela
Ospina, Luis Fernando
Isaza, Gustavo
Pérez, Jorge Enrique
dc.contributor.author.spa.fl_str_mv Cárdenas, Paola Andrea
Aragón, Diana Marcela
Ospina, Luis Fernando
Isaza, Gustavo
Pérez, Jorge Enrique
dc.subject.proposal.spa.fl_str_mv Critoniella acuminata
desgranulación
elastasa
mieloperoxidasa
Phenax rugosus
Salvia rubescens
Tabebuia chrysanta
Critoniella acuminata
degranulation
elastase
myeloperoxidase
Phenax rugosus
Salvia rubescens
Tabebuia chrysanta
topic Critoniella acuminata
desgranulación
elastasa
mieloperoxidasa
Phenax rugosus
Salvia rubescens
Tabebuia chrysanta
Critoniella acuminata
degranulation
elastase
myeloperoxidase
Phenax rugosus
Salvia rubescens
Tabebuia chrysanta
description In this work, the effect of aqueous and methanolic extracts of the plants species Critoniella acuminata, Salvia rubescens, Phenax rugosus (Poir.) Wedd and Tabebuia chrysanta G. on the enzymes elastase and myeloperoxidase, involved in degranulation leukocyte process, was evaluated, identifying the potential direct inhibitory effect on the enzyme and/or inhibition of the desgranulation of polymorphonuclear neutrophils. Extracts of Critoniella acuminata andSalvia rubescens presented effects on the degranulation process and the inhibition of the enzyme elastase and myeloperoxidase; the extracts of Phenax rugosus do not showed significant effect. Tabebuia chrysanta methanolic extract only showed effect on inhibition of elastase activity.
publishDate 2012
dc.date.issued.spa.fl_str_mv 2012
dc.date.accessioned.spa.fl_str_mv 2019-06-29T08:34:45Z
dc.date.available.spa.fl_str_mv 2019-06-29T08:34:45Z
dc.type.spa.fl_str_mv Artículo de revista
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/article
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.coarversion.spa.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/ART
format http://purl.org/coar/resource_type/c_6501
status_str publishedVersion
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/49311
dc.identifier.eprints.spa.fl_str_mv http://bdigital.unal.edu.co/42768/
http://bdigital.unal.edu.co/42768/2/
url https://repositorio.unal.edu.co/handle/unal/49311
http://bdigital.unal.edu.co/42768/
http://bdigital.unal.edu.co/42768/2/
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.spa.fl_str_mv http://revistas.unal.edu.co/index.php/rccquifa/article/view/45094
dc.relation.ispartof.spa.fl_str_mv Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico Farmacéuticas
Revista Colombiana de Ciencias Químico Farmacéuticas
dc.relation.ispartofseries.none.fl_str_mv Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 2 (2012); 157-166 0034-7418 1909-6356
dc.relation.references.spa.fl_str_mv Cárdenas, Paola Andrea and Aragón, Diana Marcela and Ospina, Luis Fernando and Isaza, Gustavo and Pérez, Jorge Enrique (2012) Effect of some antiinflammatory plant species on elastase and myeloperoxidase enzyme activity. Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 2 (2012); 157-166 0034-7418 1909-6356 .
dc.rights.spa.fl_str_mv Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.spa.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
Derechos reservados - Universidad Nacional de Colombia
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Revista Colombiana de Ciencias Químico Farmacéuticas
institution Universidad Nacional de Colombia
bitstream.url.fl_str_mv https://repositorio.unal.edu.co/bitstream/unal/49311/1/45094-216205-1-SM.pdf
https://repositorio.unal.edu.co/bitstream/unal/49311/2/45094-216205-1-SM.pdf.jpg
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bitstream.checksumAlgorithm.fl_str_mv MD5
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repository.name.fl_str_mv Repositorio Institucional Universidad Nacional de Colombia
repository.mail.fl_str_mv repositorio_nal@unal.edu.co
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