Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute
The method by which to obtain Hydroxyapatite to be used as bone substitute should offer specific qualities such as, high purity, performance, low cost and has to be the following, bioactive, biocompatible, it has to have osteoconductivity and it has to bond directly to the bone. In this paper, synth...
- Autores:
-
Sequeda, Luis Gonzalo
Díaz, José Milciades
Gutiérrez, Sandra Janeth
Perdomo, Sandra Janeth
Gómez, Olga Lucía
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2012
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/49250
- Acceso en línea:
- https://repositorio.unal.edu.co/handle/unal/49250
http://bdigital.unal.edu.co/42707/
http://bdigital.unal.edu.co/42707/2/
- Palabra clave:
- hidroxiapatita (HAp)
hueso bovino
UV-Vis
FTIR
XRD
SEM
EDX
hydroxyapatite (HAp)
bovine bone
UV-Vis
FTIR
XRD
SEM
EDX
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
| id |
UNACIONAL2_0c7aca558b98be0b59e70e6f991c3398 |
|---|---|
| oai_identifier_str |
oai:repositorio.unal.edu.co:unal/49250 |
| network_acronym_str |
UNACIONAL2 |
| network_name_str |
Universidad Nacional de Colombia |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute |
| title |
Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute |
| spellingShingle |
Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute hidroxiapatita (HAp) hueso bovino UV-Vis FTIR XRD SEM EDX hydroxyapatite (HAp) bovine bone UV-Vis FTIR XRD SEM EDX |
| title_short |
Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute |
| title_full |
Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute |
| title_fullStr |
Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute |
| title_full_unstemmed |
Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute |
| title_sort |
Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute |
| dc.creator.fl_str_mv |
Sequeda, Luis Gonzalo Díaz, José Milciades Gutiérrez, Sandra Janeth Perdomo, Sandra Janeth Gómez, Olga Lucía |
| dc.contributor.author.spa.fl_str_mv |
Sequeda, Luis Gonzalo Díaz, José Milciades Gutiérrez, Sandra Janeth Perdomo, Sandra Janeth Gómez, Olga Lucía |
| dc.subject.proposal.spa.fl_str_mv |
hidroxiapatita (HAp) hueso bovino UV-Vis FTIR XRD SEM EDX hydroxyapatite (HAp) bovine bone UV-Vis FTIR XRD SEM EDX |
| topic |
hidroxiapatita (HAp) hueso bovino UV-Vis FTIR XRD SEM EDX hydroxyapatite (HAp) bovine bone UV-Vis FTIR XRD SEM EDX |
| description |
The method by which to obtain Hydroxyapatite to be used as bone substitute should offer specific qualities such as, high purity, performance, low cost and has to be the following, bioactive, biocompatible, it has to have osteoconductivity and it has to bond directly to the bone. In this paper, synthetic HAp was prepared using 3 different methods reported in the literature as a route via sintering and precipitation, and subsequently characterized by atomic absorption spectrometry (AAS), molecular absorption spectrometry (UV-Vis), infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy X-ray (EDX). The route of synthesis of HAp precipitation gives better results, compared to the commercial standard sample and bovine bone, such as grain size which is of about 1 µm, molar ratio Ca/P of 1.7, high purity and crystallinity, while the results obtained via sintering show the presence of amorphous phases. The synthesis method using a wet precipitation of calcium nitrates and phosphates is practical and suitable for the immobilization of HAp on a metal substrate such as silicon, important for the use in dental and medical reconstructive surgery. |
| publishDate |
2012 |
| dc.date.issued.spa.fl_str_mv |
2012 |
| dc.date.accessioned.spa.fl_str_mv |
2019-06-29T08:31:22Z |
| dc.date.available.spa.fl_str_mv |
2019-06-29T08:31:22Z |
| dc.type.spa.fl_str_mv |
Artículo de revista |
| dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
| dc.type.coarversion.spa.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.content.spa.fl_str_mv |
Text |
| dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
| format |
http://purl.org/coar/resource_type/c_6501 |
| status_str |
publishedVersion |
| dc.identifier.uri.none.fl_str_mv |
https://repositorio.unal.edu.co/handle/unal/49250 |
| dc.identifier.eprints.spa.fl_str_mv |
http://bdigital.unal.edu.co/42707/ http://bdigital.unal.edu.co/42707/2/ |
| url |
https://repositorio.unal.edu.co/handle/unal/49250 http://bdigital.unal.edu.co/42707/ http://bdigital.unal.edu.co/42707/2/ |
| dc.language.iso.spa.fl_str_mv |
spa |
| language |
spa |
| dc.relation.spa.fl_str_mv |
http://revistas.unal.edu.co/index.php/rccquifa/article/view/44865 |
| dc.relation.ispartof.spa.fl_str_mv |
Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico Farmacéuticas Revista Colombiana de Ciencias Químico Farmacéuticas |
| dc.relation.ispartofseries.none.fl_str_mv |
Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 1 (2012); 50-66 0034-7418 1909-6356 |
| dc.relation.references.spa.fl_str_mv |
Sequeda, Luis Gonzalo and Díaz, José Milciades and Gutiérrez, Sandra Janeth and Perdomo, Sandra Janeth and Gómez, Olga Lucía (2012) Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute. Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 1 (2012); 50-66 0034-7418 1909-6356 . |
| dc.rights.spa.fl_str_mv |
Derechos reservados - Universidad Nacional de Colombia |
| dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| dc.rights.license.spa.fl_str_mv |
Atribución-NoComercial 4.0 Internacional |
| dc.rights.uri.spa.fl_str_mv |
http://creativecommons.org/licenses/by-nc/4.0/ |
| dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
Atribución-NoComercial 4.0 Internacional Derechos reservados - Universidad Nacional de Colombia http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.publisher.spa.fl_str_mv |
Revista Colombiana de Ciencias Químico Farmacéuticas |
| institution |
Universidad Nacional de Colombia |
| bitstream.url.fl_str_mv |
https://repositorio.unal.edu.co/bitstream/unal/49250/1/44865-214879-1-SM.pdf https://repositorio.unal.edu.co/bitstream/unal/49250/2/44865-214879-1-SM.pdf.jpg |
| bitstream.checksum.fl_str_mv |
bb8e9ff8c985608b8842774abd399afa 1db7e11ae9fb0b148b9a87ba486ae68c |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Institucional Universidad Nacional de Colombia |
| repository.mail.fl_str_mv |
repositorio_nal@unal.edu.co |
| _version_ |
1814090143395479552 |
| spelling |
Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Sequeda, Luis Gonzaloacd3e92a-3321-4cb7-af57-b45b23a91396300Díaz, José Milciades2ae260f4-b19a-4740-bd0c-bd083064a1f4300Gutiérrez, Sandra Janethaa9d608f-55fc-4d32-975f-f59950fd345b300Perdomo, Sandra Janeth1d8f7507-e724-4522-b9c2-1ff5003f6c9c300Gómez, Olga Lucíabe61f55f-4bed-4b99-8f70-eaba35bde0e73002019-06-29T08:31:22Z2019-06-29T08:31:22Z2012https://repositorio.unal.edu.co/handle/unal/49250http://bdigital.unal.edu.co/42707/http://bdigital.unal.edu.co/42707/2/The method by which to obtain Hydroxyapatite to be used as bone substitute should offer specific qualities such as, high purity, performance, low cost and has to be the following, bioactive, biocompatible, it has to have osteoconductivity and it has to bond directly to the bone. In this paper, synthetic HAp was prepared using 3 different methods reported in the literature as a route via sintering and precipitation, and subsequently characterized by atomic absorption spectrometry (AAS), molecular absorption spectrometry (UV-Vis), infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and energy dispersive spectroscopy X-ray (EDX). The route of synthesis of HAp precipitation gives better results, compared to the commercial standard sample and bovine bone, such as grain size which is of about 1 µm, molar ratio Ca/P of 1.7, high purity and crystallinity, while the results obtained via sintering show the presence of amorphous phases. The synthesis method using a wet precipitation of calcium nitrates and phosphates is practical and suitable for the immobilization of HAp on a metal substrate such as silicon, important for the use in dental and medical reconstructive surgery.El método de obtención de la hidroxiapatita (HAp) para ser utilizada como sustituto óseo, debe ofrecer un producto de alta pureza, rendimiento, rapidez y bajo costo, y contar con propiedades como bioactividad, biocompatibilidad, osteoconductividad y unión directa al hueso. En este trabajo se elaboró HAp sintética mediante tres métodos reportados en la literatura de vía sinterización y vía precipitación. El material obtenido se caracterizó por espectrometría de absorción atómica (AAS), espectrometría de absorción molecular (UV-Vis), espectroscopía infrarroja con transformada de Fourier (FTIR), difracción de rayos X (XRD), microscopía electrónica de barrido (SEM) y espectroscopía por dispersión de energía de rayos X (EDX). La ruta de síntesis de HAp por precipitación ofreció mejores resultados, comparados con la muestra estándar comercial y el hueso bovino, obteniéndose un tamaño de grano aproximado de 1 µm, relación molar Ca/P de 1,7, alta pureza y cristalinidad; mientras que los resultados obtenidos por vía sinterización mostraron la presencia de fases amorfas. El método de síntesis por precipitación vía húmeda usando nitratos de calcio y fosfatos, mostró ser práctico y adecuado para realizar la inmovilización de HAp sobre un soporte metálico como silicio, importante para su uso en cirugía reconstructiva en el área odontológica y médica.application/pdfspaRevista Colombiana de Ciencias Químico Farmacéuticashttp://revistas.unal.edu.co/index.php/rccquifa/article/view/44865Universidad Nacional de Colombia Revistas electrónicas UN Revista Colombiana de Ciencias Químico FarmacéuticasRevista Colombiana de Ciencias Químico FarmacéuticasRevista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 1 (2012); 50-66 0034-7418 1909-6356Sequeda, Luis Gonzalo and Díaz, José Milciades and Gutiérrez, Sandra Janeth and Perdomo, Sandra Janeth and Gómez, Olga Lucía (2012) Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substitute. Revista Colombiana de Ciencias Químico Farmacéuticas; Vol. 41, núm. 1 (2012); 50-66 0034-7418 1909-6356 .Synthetic hydroxyapatite obtaining using three different methods and characterization to use it as bone substituteArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARThidroxiapatita (HAp)hueso bovinoUV-VisFTIRXRDSEMEDXhydroxyapatite (HAp)bovine boneUV-VisFTIRXRDSEMEDXORIGINAL44865-214879-1-SM.pdfapplication/pdf1506128https://repositorio.unal.edu.co/bitstream/unal/49250/1/44865-214879-1-SM.pdfbb8e9ff8c985608b8842774abd399afaMD51THUMBNAIL44865-214879-1-SM.pdf.jpg44865-214879-1-SM.pdf.jpgGenerated Thumbnailimage/jpeg6713https://repositorio.unal.edu.co/bitstream/unal/49250/2/44865-214879-1-SM.pdf.jpg1db7e11ae9fb0b148b9a87ba486ae68cMD52unal/49250oai:repositorio.unal.edu.co:unal/492502022-12-14 23:03:32.715Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co |