Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva

ilustraciones, diagramas, tablas

Autores:
Orduña Lopez, Kristian Camilo
Tipo de recurso:
Fecha de publicación:
2024
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/86600
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/86600
https://repositorio.unal.edu.co/
Palabra clave:
610 - Medicina y salud::617 - Cirugía, medicina regional, odontología, oftalmología, otología, audiología
610 - Medicina y salud::616 - Enfermedades
Sistemas Neurosecretores
Complicaciones Posoperatorias
Acromegalia
Prolactinoma
Hipersecreción de la Hormona Adrenocorticotrópica Pituitaria (HACT)
Hipertiroidismo
Neurosecretory Systems
Postoperative Complications
Acromegaly
Pituitary ACTH Hypersecretion
Hyperthyroidism
Adenoma hipofisiario
Cirugía transesfenoidal endoscópica
Complicaciones
Pituitary adenoma
Transsphenoidal endoscopic surgery
Complications
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
id UNACIONAL2_04941593120c342510034c4a1e3c435c
oai_identifier_str oai:repositorio.unal.edu.co:unal/86600
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva
dc.title.translated.eng.fl_str_mv Factors associated with intra and postoperative complications in patients with pituitary adenomas who were taken to transsphenoidal surgery. Multicentric descriptive cohort study – retrospective
title Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva
spellingShingle Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva
610 - Medicina y salud::617 - Cirugía, medicina regional, odontología, oftalmología, otología, audiología
610 - Medicina y salud::616 - Enfermedades
Sistemas Neurosecretores
Complicaciones Posoperatorias
Acromegalia
Prolactinoma
Hipersecreción de la Hormona Adrenocorticotrópica Pituitaria (HACT)
Hipertiroidismo
Neurosecretory Systems
Postoperative Complications
Acromegaly
Pituitary ACTH Hypersecretion
Hyperthyroidism
Adenoma hipofisiario
Cirugía transesfenoidal endoscópica
Complicaciones
Pituitary adenoma
Transsphenoidal endoscopic surgery
Complications
title_short Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva
title_full Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva
title_fullStr Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva
title_full_unstemmed Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva
title_sort Factores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectiva
dc.creator.fl_str_mv Orduña Lopez, Kristian Camilo
dc.contributor.advisor.none.fl_str_mv Arias Guatibonza, Jaime Andelfo
dc.contributor.author.none.fl_str_mv Orduña Lopez, Kristian Camilo
dc.subject.ddc.spa.fl_str_mv 610 - Medicina y salud::617 - Cirugía, medicina regional, odontología, oftalmología, otología, audiología
610 - Medicina y salud::616 - Enfermedades
topic 610 - Medicina y salud::617 - Cirugía, medicina regional, odontología, oftalmología, otología, audiología
610 - Medicina y salud::616 - Enfermedades
Sistemas Neurosecretores
Complicaciones Posoperatorias
Acromegalia
Prolactinoma
Hipersecreción de la Hormona Adrenocorticotrópica Pituitaria (HACT)
Hipertiroidismo
Neurosecretory Systems
Postoperative Complications
Acromegaly
Pituitary ACTH Hypersecretion
Hyperthyroidism
Adenoma hipofisiario
Cirugía transesfenoidal endoscópica
Complicaciones
Pituitary adenoma
Transsphenoidal endoscopic surgery
Complications
dc.subject.decs.spa.fl_str_mv Sistemas Neurosecretores
Complicaciones Posoperatorias
Acromegalia
Prolactinoma
Hipersecreción de la Hormona Adrenocorticotrópica Pituitaria (HACT)
Hipertiroidismo
dc.subject.decs.eng.fl_str_mv Neurosecretory Systems
Postoperative Complications
Acromegaly
Pituitary ACTH Hypersecretion
Hyperthyroidism
dc.subject.proposal.spa.fl_str_mv Adenoma hipofisiario
Cirugía transesfenoidal endoscópica
Complicaciones
dc.subject.proposal.eng.fl_str_mv Pituitary adenoma
Transsphenoidal endoscopic surgery
Complications
description ilustraciones, diagramas, tablas
publishDate 2024
dc.date.accessioned.none.fl_str_mv 2024-07-23T20:13:10Z
dc.date.available.none.fl_str_mv 2024-07-23T20:13:10Z
dc.date.issued.none.fl_str_mv 2024
dc.type.spa.fl_str_mv Trabajo de grado - Especialidad Médica
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/TM
status_str acceptedVersion
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/86600
dc.identifier.instname.spa.fl_str_mv Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv https://repositorio.unal.edu.co/
url https://repositorio.unal.edu.co/handle/unal/86600
https://repositorio.unal.edu.co/
identifier_str_mv Universidad Nacional de Colombia
Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.references.spa.fl_str_mv Molitch ME. Diagnosis and treatment of pituitary adenomas: a review. JAMA. 2017;317(5):516-524. doi:10.1001/jama.2016.19699
Melmed S. Pituitary-tumor endocrinopathies. N Engl J Med. 2020;382(10):937- 950. doi:10.1056/ NEJMra1810772
Hall WA, Luciano MG, Doppman JL, Patronas NJ, Oldfield EH. Pituitary magnetic resonance imaging in normal human volunteers: occult adenomas in the general population. Ann Intern Med. 1994;120 (10):817-820. doi:10.7326/0003- 4819-120-10-199405150-00001
Molitch ME. Nonfunctioning pituitary tumors. Handb Clin Neurol. 2014;124:167-184. doi:10.1016/ B978-0-444-59602-4.00012-5
Daly AF, Rixhon M, Adam C, Dempegioti A, Tichomirowa MA, Beckers A. High prevalence of pituitary adenomas: a cross-sectional study in the province of Liege, Belgium. J Clin Endocrinol Metab. 2006;91(12):4769-4775. doi:10.1210/jc.2006- 1668
Day PF, Loto MG, Glerean M, Picasso MF, Lovazzano S, Giunta DH. Incidence and prevalence of clinically relevant pituitary adenomas: retrospective cohort study in a health management organization in Buenos Aires, Argentina. Arch Endocrinol Metab. 2016;60(6):554-561. doi:10. 1590/2359-3997000000195
Pappachan JM, Raskauskiene D, Kutty VR, Clayton RN. Excess mortality associated with hypopituitarism in adults: a meta-analysis of observational studies. J Clin Endocrinol Metab. 2015;100(4):1405-1411. doi:10.1210/jc.2014-3787
Limumpornpetch P, Morgan AW, Tiganescu A, et al. The effect of endogenous Cushing syndrome on all-cause and cause-specific mortality. J Clin Endocrinol Metab. 2022;107(8):2377-2388. doi:10. 1210/clinem/dgac265
Molitch ME. Nonfunctioning pituitary tumors and pituitary incidentalomas. Endocrinol Metab Clin North Am. 2008;37(1):151-171. doi:10.1016/j.ecl. 2007.10.011
Lacroix A, Feelders RA, Stratakis CA, Nieman LK. Cushing’s syndrome. Lancet. 2015;386(9996): 913-927. doi:10.1016/S0140-6736(14)61375-1
Amlashi FG, Tritos NA. Thyrotropin-secreting pituitary adenomas: epidemiology, diagnosis, and management. Endocrine. 2016;52(3):427-440. doi: 10.1007/s12020-016-0863-3
Tritos NA, Klibanski A. Prolactin and its role in human reproduction. In: Strauss J, Barbieri RL, Gargiulo A, eds. Yen and Jaffe’s Reproductive Endocrinology. 8th ed. Elsevier Science; 2018:58-74
Melmed S, Kaiser UB, Lopes MB, et al. Clinical biology of the pituitary adenoma. Endocr Rev. 2022;43(6):1003-1037. doi:10.1210/endrev/bnac010
Ben-Shlomo A, Melmed S. Acromegaly. Endocrinol Metab Clin North Am. 2008;37(1):101-122. doi:10.1016/j.ecl.2007.10.002
Dal J, Leisner MZ, Hermansen K, et al. Cancer incidence in patients with acromegaly: a cohort study and meta-analysis of the literature. J Clin Endocrinol Metab. 2018;103(6):2182-2188. doi:10. 1210/jc.2017-02457
Pivonello R, De Martino MC, De Leo M, Lombardi G, Colao A. Cushing’s syndrome. Endocrinol Metab Clin North Am. 2008;37(1):135-149. doi:10.1016/j.ecl.2007.10.010
Nieman LK, Biller BM, Findling JW, et al. The diagnosis of Cushing’s syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2008;93(5):1526-1540. doi:10.1210/jc. 2008-0125
Melmed S, Casanueva FF, Hoffman AR, et al; Endocrine Society. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96 (2):273-288. doi:10.1210/jc.2010-1692
Katznelson L, Laws ER Jr, Melmed S, et al; Endocrine Society. Acromegaly: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2014;99(11):3933-3951. doi:10.1210/jc.2014-2700
Ribeiro-Oliveira A Jr, Faje AT, Barkan AL. Limited utility of oral glucose tolerance test in biochemically active acromegaly. Eur J Endocrinol. 2011;164(1):17-22. doi:10.1530/EJE-10-0744
Fleseriu M, Auchus R, Bancos I, et al. Consensus on diagnosis and management of Cushing’s disease: a guideline update. Lancet Diabetes Endocrinol. 2021;9(12):847-875. doi:10.1016/S2213-8587(21) 00235-7
Hong AR, Kim JH, Hong ES, et al. Limited diagnostic utility of plasma adrenocorticotropic hormone for differentiation between adrenal Cushing syndrome and Cushing disease. Endocrinol Metab (Seoul). 2015;30(3):297-304. doi:10.3803/ EnM.2015.30.3.297
Beck-Peccoz P, Lania A, Beckers A, Chatterjee K, Wemeau JL. 2013 European thyroid association guidelines for the diagnosis and treatment of 47 thyrotropin-secreting pituitary tumors. Eur Thyroid J. 2013;2(2):76-82. doi:10.1159/000351007
MacFarlane J, Bashari WA, Senanayake R, et al. Advances in the imaging of pituitary tumors. Endocrinol Metab Clin North Am. 2020;49(3):357-373. doi:10.1016/j.ecl.2020.06.002
Wright K, Chaker L, Pacione D, et al. Determinants of surgical remission in prolactinomas: a systematic review and meta-analysis. World Neurosurg. 2021;154:e349-e369. doi:10.1016/j.wneu.2021.07.035
Starnoni D, Daniel RT, Marino L, Pitteloud N, Levivier M, Messerer M. Surgical treatment of acromegaly according to the 2010 remission criteria: systematic review and meta-analysis. Acta Neurochir (Wien). 2016;158(11):2109-2121. doi:10. 1007/s00701-016-2903-4
Nieman LK, Biller BM, Findling JW, et al; Endocrine Society. Treatment of Cushing’s syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2015;100(8): 2807-2831. doi:10.1210/jc.2015-1818
Stroud A, Dhaliwal P, Alvarado R, et al. Outcomes of pituitary surgery for Cushing’s disease: a systematic review and meta-analysis. Pituitary. 2020;23(5):595-609. doi:10.1007/s11102-020-01066-8
Wang AT, Mullan RJ, Lane MA, et al. Treatment of hyperprolactinemia: a systematic review and meta-analysis. Syst Rev. 2012;1(1):33. doi:10.1186/ 2046- 4053-1-33
Luger A, Broersen LHA, Biermasz NR, et al. ESE clinical practice guideline on functioning and nonfunctioning pituitary adenomas in pregnancy. Eur J Endocrinol. 2021;185(3):G1-G33. doi:10.1530/ EJE-21-0462
Zamanipoor Najafabadi AH, Zandbergen IM, de Vries F, et al. Surgery as a viable alternative first-line treatment for prolactinoma patients: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2020;105(3):e32-e41. doi:10. 1210/clinem/dgz144
Carmichael JD, Bonert VS, Nuño M, Ly D, Melmed S. Acromegaly clinical trial methodology impact on reported biochemical efficacy rates of somatostatin receptor ligand treatments: a meta-analysis. J Clin Endocrinol Metab. 2014;99 (5):1825-1833. doi:10.1210/jc.2013-3757
Loeffler JS, Shih HA. Radiation therapy in the management of pituitary adenomas. J Clin Endocrinol Metab. 2011;96(7):1992-2003. doi:10. 1210/jc.2011- 0251
Mathieu D, Kotecha R, Sahgal A, et al. Stereotactic radiosurgery for secretory pituitary adenomas: systematic review and International Stereotactic Radiosurgery Society practice recommendations. J Neurosurg. 2021;136(3):801-812. doi:10.3171/2021.2.JNS204440
Bengtsson, O.F., Sunnergren, O., Segerhammar, I. et al. Remission, complications, and overall survival in transsphenoidal pituitary surgery—a Swedish single-center experience of 578 patients. Acta Neurochir 165, 685–692 (2023). https://doi.org/10.1007/s00701-022-05456-8
Alzhrani, G., Sivakumar, W., Park, M. S., Taussky, P., & Couldwell, W. T. (2018). Delayed Complications After Transsphenoidal Surgery for Pituitary Adenomas. World Neurosurgery, 109, 233–241. doi:10.1016/j.wneu.2017.09.192
Araujo-Castro M, Acitores Cancela A, Vior C, Pascual-Corrales E, Rodríguez Berrocal V. Radiological Knosp, Revised-Knosp, and Hardy-Wilson Classifications for the Prediction of Surgical Outcomes in the Endoscopic Endonasal Surgery of Pituitary Adenomas: Study of 228 Cases. Front Oncol. 2022 Jan 20;11:807040. doi: 10.3389/fonc.2021.807040. PMID: 35127519; PMCID: PMC8810816
Knosp, Engelbert M.D.; Steiner, Erich M.D.; Kitz, Klaus M.D; Matula, Christian M.D.. Pituitary Adenomas with Invasion of the Cavernous Sinus Space: A Magnetic Resonance Imaging Classification Compared with Surgical Findings. Neurosurgery 33(4):p 610-618, October 1993
Staartjes, V. E., Serra, C., Zoli, M., Mazzatenta, D., Pozzi, F., Locatelli, D., … Regli, L. (2020). Multicenter external validation of the Zurich Pituitary Score. Acta Neurochirurgica. doi:10.1007/s00701-020-04286-w
Hadad G, Bassagasteguy L, Carrau RL, Mataza JC, Kassam A, Snyderman CH, Mintz A. A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap. Laryngoscope. 2006 Oct;116(10):1882-6.
Yamada S. Sublabial transsphenoidal pituitary surgery: a new modified technique for a less-invasive sublabial approach. Biomed Pharmacother. 2002;56 Suppl 1:165s-170s
Zubair A, M Das J. Transsphenoidal Hypophysectomy. [Updated 2023 Jun 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556142/
Sethi, K.S., Choudhary, S., Ganesan, P.K. et al. Sphenoid sinus anatomical variants and pathologies: pictorial essay. Neuroradiology 65, 1187–1203 (2023). https://doi.org/10.1007/s00234-023-03163-4
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dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.spa.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.extent.spa.fl_str_mv 50 páginas
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dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia
dc.publisher.program.spa.fl_str_mv Bogotá - Medicina - Especialidad en Neurocirugía
dc.publisher.faculty.spa.fl_str_mv Facultad de Medicina
dc.publisher.place.spa.fl_str_mv Bogotá, Colombia
dc.publisher.branch.spa.fl_str_mv Universidad Nacional de Colombia - Sede Bogotá
institution Universidad Nacional de Colombia
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spelling Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Arias Guatibonza, Jaime Andelfo9c23cc30e84ca7b90172e816dfcc8a8b600Orduña Lopez, Kristian Camilo54f0371128a88caf404bb635c1d5b6172024-07-23T20:13:10Z2024-07-23T20:13:10Z2024https://repositorio.unal.edu.co/handle/unal/86600Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramas, tablasLos adenomas hipofisiarios son la décima parte de las lesiones intracraneanas, y corresponden al 20 a 50 % de lesiones intraselares, que al causar síntomas de desorden neuroendocrino o efecto de masa local requieren tratamiento quirúrgico, por medio de resección transesfenoidal endoscópica. Siendo el estándar de oro, por demostrar mejores resultados respecto volumen de resección tumoral y menor tasa de complicaciones a comparación con a la cirugía abierta. Por ende, se intenta evaluar, la distribución histopatológica en la población Colombiana en un estudio multicéntrico descriptivo retrospectivo con análisis multivariable para demostrar su asociación de patologías y condiciones perioperatorias para el desarrollo de complicaciones trans y post quirúrgica (Texto tomado de la fuente).Pituitary adenomas are one-tenth of intracranial lesions and account for 20 to 50% of intrasellar lesions. They cause symptoms of neuroendocrine disorder or local mass effect, requiring surgical treatment through endoscopic transsphenoidal resection, which is the gold standard due to demonstrating better results regarding tumor resection volume and lower complication rates compared to open surgery. Therefore, a multicenter descriptive retrospective study with multivariable analysis is being attempted to evaluate the histopathological distribution in the Colombian population to demonstrate its association with perioperative pathologies and conditions for the development of trans and postsurgical complications.Especialidades MédicasEspecialista en Neurocirugía50 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Especialidad en NeurocirugíaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::617 - Cirugía, medicina regional, odontología, oftalmología, otología, audiología610 - Medicina y salud::616 - EnfermedadesSistemas NeurosecretoresComplicaciones PosoperatoriasAcromegaliaProlactinomaHipersecreción de la Hormona Adrenocorticotrópica Pituitaria (HACT)HipertiroidismoNeurosecretory SystemsPostoperative ComplicationsAcromegalyPituitary ACTH HypersecretionHyperthyroidismAdenoma hipofisiarioCirugía transesfenoidal endoscópicaComplicacionesPituitary adenomaTranssphenoidal endoscopic surgeryComplicationsFactores asociados a las complicaciones intra y postoperatorias en pacientes con adenomas hipofisiarios que fueron llevados a cirugía transesfenoidal. Estudio multicéntrico de cohorte descriptiva – retrospectivaFactors associated with intra and postoperative complications in patients with pituitary adenomas who were taken to transsphenoidal surgery. Multicentric descriptive cohort study – retrospectiveTrabajo de grado - Especialidad Médicainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMMolitch ME. Diagnosis and treatment of pituitary adenomas: a review. JAMA. 2017;317(5):516-524. doi:10.1001/jama.2016.19699Melmed S. Pituitary-tumor endocrinopathies. N Engl J Med. 2020;382(10):937- 950. doi:10.1056/ NEJMra1810772Hall WA, Luciano MG, Doppman JL, Patronas NJ, Oldfield EH. Pituitary magnetic resonance imaging in normal human volunteers: occult adenomas in the general population. Ann Intern Med. 1994;120 (10):817-820. doi:10.7326/0003- 4819-120-10-199405150-00001Molitch ME. Nonfunctioning pituitary tumors. Handb Clin Neurol. 2014;124:167-184. doi:10.1016/ B978-0-444-59602-4.00012-5Daly AF, Rixhon M, Adam C, Dempegioti A, Tichomirowa MA, Beckers A. High prevalence of pituitary adenomas: a cross-sectional study in the province of Liege, Belgium. J Clin Endocrinol Metab. 2006;91(12):4769-4775. doi:10.1210/jc.2006- 1668Day PF, Loto MG, Glerean M, Picasso MF, Lovazzano S, Giunta DH. Incidence and prevalence of clinically relevant pituitary adenomas: retrospective cohort study in a health management organization in Buenos Aires, Argentina. Arch Endocrinol Metab. 2016;60(6):554-561. doi:10. 1590/2359-3997000000195Pappachan JM, Raskauskiene D, Kutty VR, Clayton RN. Excess mortality associated with hypopituitarism in adults: a meta-analysis of observational studies. J Clin Endocrinol Metab. 2015;100(4):1405-1411. doi:10.1210/jc.2014-3787Limumpornpetch P, Morgan AW, Tiganescu A, et al. The effect of endogenous Cushing syndrome on all-cause and cause-specific mortality. J Clin Endocrinol Metab. 2022;107(8):2377-2388. doi:10. 1210/clinem/dgac265Molitch ME. Nonfunctioning pituitary tumors and pituitary incidentalomas. Endocrinol Metab Clin North Am. 2008;37(1):151-171. doi:10.1016/j.ecl. 2007.10.011Lacroix A, Feelders RA, Stratakis CA, Nieman LK. Cushing’s syndrome. Lancet. 2015;386(9996): 913-927. doi:10.1016/S0140-6736(14)61375-1Amlashi FG, Tritos NA. Thyrotropin-secreting pituitary adenomas: epidemiology, diagnosis, and management. Endocrine. 2016;52(3):427-440. doi: 10.1007/s12020-016-0863-3Tritos NA, Klibanski A. Prolactin and its role in human reproduction. In: Strauss J, Barbieri RL, Gargiulo A, eds. Yen and Jaffe’s Reproductive Endocrinology. 8th ed. Elsevier Science; 2018:58-74Melmed S, Kaiser UB, Lopes MB, et al. Clinical biology of the pituitary adenoma. Endocr Rev. 2022;43(6):1003-1037. doi:10.1210/endrev/bnac010Ben-Shlomo A, Melmed S. Acromegaly. Endocrinol Metab Clin North Am. 2008;37(1):101-122. doi:10.1016/j.ecl.2007.10.002Dal J, Leisner MZ, Hermansen K, et al. Cancer incidence in patients with acromegaly: a cohort study and meta-analysis of the literature. J Clin Endocrinol Metab. 2018;103(6):2182-2188. doi:10. 1210/jc.2017-02457Pivonello R, De Martino MC, De Leo M, Lombardi G, Colao A. Cushing’s syndrome. Endocrinol Metab Clin North Am. 2008;37(1):135-149. doi:10.1016/j.ecl.2007.10.010Nieman LK, Biller BM, Findling JW, et al. The diagnosis of Cushing’s syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2008;93(5):1526-1540. doi:10.1210/jc. 2008-0125Melmed S, Casanueva FF, Hoffman AR, et al; Endocrine Society. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96 (2):273-288. doi:10.1210/jc.2010-1692Katznelson L, Laws ER Jr, Melmed S, et al; Endocrine Society. 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Neuroradiology 65, 1187–1203 (2023). https://doi.org/10.1007/s00234-023-03163-4AdministradoresBibliotecariosConsejerosEstudiantesInvestigadoresMaestrosLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/86600/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL1031144240.2024.pdf1031144240.2024.pdftrabajo de grado especialización en Neurocirugíaapplication/pdf1016115https://repositorio.unal.edu.co/bitstream/unal/86600/3/1031144240.2024.pdfbffe29a4eb70efde5e247ec099b3d21eMD53THUMBNAIL1031144240.2024.pdf.jpg1031144240.2024.pdf.jpgGenerated Thumbnailimage/jpeg4157https://repositorio.unal.edu.co/bitstream/unal/86600/4/1031144240.2024.pdf.jpg94b49a782e6b751a6c11ff11f4d628b7MD54unal/86600oai:repositorio.unal.edu.co:unal/866002024-07-23 23:17:15.827Repositorio Institucional Universidad Nacional de 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