Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea
Background. In patients with obstructive sleep apnea syndrome (OSAS) treatment with CPAP results in an increase of REM sleep and slow wave sleep, but there is limited information about the prevalence of REM rebound in patients with OSAS and possible factors related to the rebound. Objective. REM reb...
- Autores:
-
Osuna Suárez, Édgar
Siddiqui, Fouzia
Vanegas, Marco A.
Walters, Arthur S.
Chokroverty, Sudhansu
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2008
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/29927
- Acceso en línea:
- https://repositorio.unal.edu.co/handle/unal/29927
http://bdigital.unal.edu.co/20001/
- Palabra clave:
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
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dc.title.spa.fl_str_mv |
Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea |
title |
Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea |
spellingShingle |
Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea |
title_short |
Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea |
title_full |
Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea |
title_fullStr |
Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea |
title_full_unstemmed |
Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea |
title_sort |
Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea |
dc.creator.fl_str_mv |
Osuna Suárez, Édgar Siddiqui, Fouzia Vanegas, Marco A. Walters, Arthur S. Chokroverty, Sudhansu |
dc.contributor.author.spa.fl_str_mv |
Osuna Suárez, Édgar Siddiqui, Fouzia Vanegas, Marco A. Walters, Arthur S. Chokroverty, Sudhansu |
description |
Background. In patients with obstructive sleep apnea syndrome (OSAS) treatment with CPAP results in an increase of REM sleep and slow wave sleep, but there is limited information about the prevalence of REM rebound in patients with OSAS and possible factors related to the rebound. Objective. REM rebound (RR) and slow wave sleep rebound (SWSR) has been described as a frequent phenomenon that occurs during CPAP titration, but the quantity that qualify for RR has not been mentioned in literature. The objective of our study was to determine the prevalence of REM rebound and slow wave sleep rebound in our sleep disorders center, to attempt to define RR and look for factors that may affect RR and SWSR on the first night of CPAP titration. Materials and methods. We included patients who had both baseline polysomnogram (bPSG) and CPAP polysomnogram (cPSG) studies done in the same laboratory. We included 179 patients and gt;18 years with Apnea hypopnea index (AHI) and gt;10/hr on the baseline study, with an adequate CPAP titration study. We compared the percentages of REM sleep and slow wave sleep during bPSG and cPSG. We analyzed the frequency of presentation and looked for the factors affecting RR and SWSR. Results. 179 patients were enrolled (M/F:118/61), with a mean age of 48.6±4 for men, and 51.6±12.9 for women. The mean interval between the bPSG and cPSG was 45 days. The mean REM percentage during the bPSG was 15.55 percent and during cPSG study it was 21.57 percent. We took 6 percent as our differential point as the results became statistically significant at this point (p:0001). We therefore present our data by dividing our patients population with RR6%. The mean SWS percentage during the bPSG was 8.11±9.68 and during the cPSG was 13.17±10, with a p:0.35 which is not statistically significant. The multiple regression model showed that the variables that contribute more to the REM change are: REM sleep during bPSG (-0.56), bAHI (0.24) and the body mass index (0.081). Conclusions. We suggest that an increase greater than 6% in REM sleep should be considered REM rebound, since 6.15 percent was the statistically significant difference between bPSG REM sleep and cPSG. The prevalence of RR in our group was 46 percent and the variables that contribute more to RR are REM sleep during bPSG, AHI at baseline and body mass index. |
publishDate |
2008 |
dc.date.issued.spa.fl_str_mv |
2008 |
dc.date.accessioned.spa.fl_str_mv |
2019-06-26T14:02:30Z |
dc.date.available.spa.fl_str_mv |
2019-06-26T14:02:30Z |
dc.type.spa.fl_str_mv |
Artículo de revista |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.content.spa.fl_str_mv |
Text |
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http://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/resource_type/c_6501 |
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publishedVersion |
dc.identifier.uri.none.fl_str_mv |
https://repositorio.unal.edu.co/handle/unal/29927 |
dc.identifier.eprints.spa.fl_str_mv |
http://bdigital.unal.edu.co/20001/ |
url |
https://repositorio.unal.edu.co/handle/unal/29927 http://bdigital.unal.edu.co/20001/ |
dc.language.iso.spa.fl_str_mv |
spa |
language |
spa |
dc.relation.spa.fl_str_mv |
http://revistas.unal.edu.co/index.php/revfacmed/article/view/16043 |
dc.relation.ispartof.spa.fl_str_mv |
Universidad Nacional de Colombia Revistas electrónicas UN Revista de la Facultad de Medicina Revista de la Facultad de Medicina |
dc.relation.ispartofseries.none.fl_str_mv |
Revista de la Facultad de Medicina; Vol. 56, núm. 1 (2008) 2357-3848 0120-0011 |
dc.relation.references.spa.fl_str_mv |
Osuna Suárez, Édgar and Siddiqui, Fouzia and Vanegas, Marco A. and Walters, Arthur S. and Chokroverty, Sudhansu (2008) Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea. Revista de la Facultad de Medicina; Vol. 56, núm. 1 (2008) 2357-3848 0120-0011 . |
dc.rights.spa.fl_str_mv |
Derechos reservados - Universidad Nacional de Colombia |
dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
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Atribución-NoComercial 4.0 Internacional |
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http://creativecommons.org/licenses/by-nc/4.0/ |
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info:eu-repo/semantics/openAccess |
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Atribución-NoComercial 4.0 Internacional Derechos reservados - Universidad Nacional de Colombia http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
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application/pdf |
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Facultad de Medicina. Universidad Nacional de Colombia. Sede Bogotá |
institution |
Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/bitstream/unal/29927/1/16043-49582-1-PB.pdf https://repositorio.unal.edu.co/bitstream/unal/29927/2/16043-49582-1-PB.pdf.jpg |
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spelling |
Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Osuna Suárez, Édgar63649a31-91ed-4393-9566-4c65bdda1bee300Siddiqui, Fouzia807d1456-3b2e-4feb-ba1f-f890d55b00a3300Vanegas, Marco A.3bc6ebea-cdb5-4ff8-9308-2bf69a6c8aa6300Walters, Arthur S.7d702fbc-da16-499e-a9e2-30184ca70719300Chokroverty, Sudhansu47d09edf-c0b2-485b-8135-86c12a7b4a033002019-06-26T14:02:30Z2019-06-26T14:02:30Z2008https://repositorio.unal.edu.co/handle/unal/29927http://bdigital.unal.edu.co/20001/Background. In patients with obstructive sleep apnea syndrome (OSAS) treatment with CPAP results in an increase of REM sleep and slow wave sleep, but there is limited information about the prevalence of REM rebound in patients with OSAS and possible factors related to the rebound. Objective. REM rebound (RR) and slow wave sleep rebound (SWSR) has been described as a frequent phenomenon that occurs during CPAP titration, but the quantity that qualify for RR has not been mentioned in literature. The objective of our study was to determine the prevalence of REM rebound and slow wave sleep rebound in our sleep disorders center, to attempt to define RR and look for factors that may affect RR and SWSR on the first night of CPAP titration. Materials and methods. We included patients who had both baseline polysomnogram (bPSG) and CPAP polysomnogram (cPSG) studies done in the same laboratory. We included 179 patients and gt;18 years with Apnea hypopnea index (AHI) and gt;10/hr on the baseline study, with an adequate CPAP titration study. We compared the percentages of REM sleep and slow wave sleep during bPSG and cPSG. We analyzed the frequency of presentation and looked for the factors affecting RR and SWSR. Results. 179 patients were enrolled (M/F:118/61), with a mean age of 48.6±4 for men, and 51.6±12.9 for women. The mean interval between the bPSG and cPSG was 45 days. The mean REM percentage during the bPSG was 15.55 percent and during cPSG study it was 21.57 percent. We took 6 percent as our differential point as the results became statistically significant at this point (p:0001). We therefore present our data by dividing our patients population with RR6%. The mean SWS percentage during the bPSG was 8.11±9.68 and during the cPSG was 13.17±10, with a p:0.35 which is not statistically significant. The multiple regression model showed that the variables that contribute more to the REM change are: REM sleep during bPSG (-0.56), bAHI (0.24) and the body mass index (0.081). Conclusions. We suggest that an increase greater than 6% in REM sleep should be considered REM rebound, since 6.15 percent was the statistically significant difference between bPSG REM sleep and cPSG. The prevalence of RR in our group was 46 percent and the variables that contribute more to RR are REM sleep during bPSG, AHI at baseline and body mass index.application/pdfspaFacultad de Medicina. Universidad Nacional de Colombia. Sede Bogotáhttp://revistas.unal.edu.co/index.php/revfacmed/article/view/16043Universidad Nacional de Colombia Revistas electrónicas UN Revista de la Facultad de MedicinaRevista de la Facultad de MedicinaRevista de la Facultad de Medicina; Vol. 56, núm. 1 (2008) 2357-3848 0120-0011Osuna Suárez, Édgar and Siddiqui, Fouzia and Vanegas, Marco A. and Walters, Arthur S. and Chokroverty, Sudhansu (2008) Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apnea. Revista de la Facultad de Medicina; Vol. 56, núm. 1 (2008) 2357-3848 0120-0011 .Prevalence and factors affecting rem and slow wave sleep rebound on cpap titration study in patients with obstructive sleep apneaArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTORIGINAL16043-49582-1-PB.pdfapplication/pdf3866015https://repositorio.unal.edu.co/bitstream/unal/29927/1/16043-49582-1-PB.pdf973f543889663a5a0a4c21f982e355eeMD51THUMBNAIL16043-49582-1-PB.pdf.jpg16043-49582-1-PB.pdf.jpgGenerated Thumbnailimage/jpeg8915https://repositorio.unal.edu.co/bitstream/unal/29927/2/16043-49582-1-PB.pdf.jpg63a3555c554ae700027a000dccb6c13fMD52unal/29927oai:repositorio.unal.edu.co:unal/299272022-11-23 23:05:27.728Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co |