Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D

La diabetes afecta a más de 463 millones de personas en el mundo, y se estima que dentro de 25 años más de 700 millones padecerán esta enfermedad. Entre las complicaciones más frecuentes están las úlceras crónicas de pie diabético (UCPD), y se estima que se presentarán en un cuarto de la población d...

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Autores:
Solarte David, Víctor Alfonso
Tipo de recurso:
Investigation report
Fecha de publicación:
2020
Institución:
Universidad Autónoma de Bucaramanga - UNAB
Repositorio:
Repositorio UNAB
Idioma:
spa
OAI Identifier:
oai:repository.unab.edu.co:20.500.12749/21358
Acceso en línea:
http://hdl.handle.net/20.500.12749/21358
Palabra clave:
Metabolism disorders
Platelet rich plasma
Blood
Three-dimensional image in design
Bioink
Diabetic foot
Diabetes
Trastornos del metabolismo
Plasma rico en plaquetas
Sangre
Imagen tridimensional en diseño
Biotinta
Pie diabético
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License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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network_name_str Repositorio UNAB
repository_id_str
dc.title.spa.fl_str_mv Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D
dc.title.translated.spa.fl_str_mv Design of a hydrogel-type bioink based on diacrylated polyethylene glycol with platelet-rich plasma, aimed at the manufacture of dressings for chronic diabetic foot ulcers by 3D bioprinting
title Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D
spellingShingle Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D
Metabolism disorders
Platelet rich plasma
Blood
Three-dimensional image in design
Bioink
Diabetic foot
Diabetes
Trastornos del metabolismo
Plasma rico en plaquetas
Sangre
Imagen tridimensional en diseño
Biotinta
Pie diabético
title_short Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D
title_full Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D
title_fullStr Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D
title_full_unstemmed Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D
title_sort Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3D
dc.creator.fl_str_mv Solarte David, Víctor Alfonso
dc.contributor.author.none.fl_str_mv Solarte David, Víctor Alfonso
dc.contributor.cvlac.spa.fl_str_mv Solarte David, Víctor Alfonso [1329391]
dc.contributor.googlescholar.spa.fl_str_mv Solarte David, Víctor Alfonso [es&oi=ao]
dc.contributor.orcid.spa.fl_str_mv Solarte David, Víctor Alfonso [0000-0002-9856-1484]
dc.contributor.apolounab.spa.fl_str_mv Solarte David, Víctor Alfonso [Victor-Solarte-David]
dc.subject.keywords.spa.fl_str_mv Metabolism disorders
Platelet rich plasma
Blood
Three-dimensional image in design
Bioink
Diabetic foot
topic Metabolism disorders
Platelet rich plasma
Blood
Three-dimensional image in design
Bioink
Diabetic foot
Diabetes
Trastornos del metabolismo
Plasma rico en plaquetas
Sangre
Imagen tridimensional en diseño
Biotinta
Pie diabético
dc.subject.lemb.spa.fl_str_mv Diabetes
Trastornos del metabolismo
Plasma rico en plaquetas
Sangre
Imagen tridimensional en diseño
dc.subject.proposal.spa.fl_str_mv Biotinta
Pie diabético
description La diabetes afecta a más de 463 millones de personas en el mundo, y se estima que dentro de 25 años más de 700 millones padecerán esta enfermedad. Entre las complicaciones más frecuentes están las úlceras crónicas de pie diabético (UCPD), y se estima que se presentarán en un cuarto de la población diabética a lo largo de su vida. Las UCPD, presentan un alto riesgo de infección convirtiéndose en la principal causa de amputaciones no traumáticas en el mundo, adicionalmente, es una enfermedad de alto costo para los sistemas de salud. En la actualidad, los tratamientos son efectivos solo en la mitad de las UCPD tratadas, lo que evidencia que los métodos terapéuticos tradicionales no son adecuados para todos los pacientes, adicionalmente, este tipo de úlceras presentan altas cantidades de metaloproteinasas (MPMs) lo que no permite la formación de matriz que lleve a la cicatrización del tejido.
publishDate 2020
dc.date.issued.none.fl_str_mv 2020
dc.date.accessioned.none.fl_str_mv 2023-08-23T12:31:47Z
dc.date.available.none.fl_str_mv 2023-08-23T12:31:47Z
dc.type.eng.fl_str_mv Research report
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_8042
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/workingPaper
dc.type.local.spa.fl_str_mv Informe de investigación
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_18ws
dc.type.hasversion.spa.fl_str_mv info:eu-repo/semantics/acceptedVersion
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dc.identifier.instname.spa.fl_str_mv instname:Universidad Autónoma de Bucaramanga - UNAB
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spelling Solarte David, Víctor Alfonso9023b799-a526-46ec-b9e8-a06fc75314dfSolarte David, Víctor Alfonso [1329391]Solarte David, Víctor Alfonso [es&oi=ao]Solarte David, Víctor Alfonso [0000-0002-9856-1484]Solarte David, Víctor Alfonso [Victor-Solarte-David]Bucaramanga (Santander, Colombia)UNAB Campus Bucaramanga2023-08-23T12:31:47Z2023-08-23T12:31:47Z2020http://hdl.handle.net/20.500.12749/21358instname:Universidad Autónoma de Bucaramanga - UNABreponame:Repositorio Institucional UNABrepourl:https://repository.unab.edu.coLa diabetes afecta a más de 463 millones de personas en el mundo, y se estima que dentro de 25 años más de 700 millones padecerán esta enfermedad. Entre las complicaciones más frecuentes están las úlceras crónicas de pie diabético (UCPD), y se estima que se presentarán en un cuarto de la población diabética a lo largo de su vida. Las UCPD, presentan un alto riesgo de infección convirtiéndose en la principal causa de amputaciones no traumáticas en el mundo, adicionalmente, es una enfermedad de alto costo para los sistemas de salud. En la actualidad, los tratamientos son efectivos solo en la mitad de las UCPD tratadas, lo que evidencia que los métodos terapéuticos tradicionales no son adecuados para todos los pacientes, adicionalmente, este tipo de úlceras presentan altas cantidades de metaloproteinasas (MPMs) lo que no permite la formación de matriz que lleve a la cicatrización del tejido.Diabetes affects more than 463 million people in the world, and it is estimated that within 25 years more than 700 million will suffer from this disease. Chronic diabetic foot ulcers (UCPD) are among the most frequent complications, and it is estimated that they will occur in a quarter of the diabetic population throughout their lives. The UCPD present a high risk of infection, becoming the main cause of non-traumatic amputations in the world, additionally, it is a high-cost disease for health systems. At present, the treatments are effective in only half of the UCPD treated, which shows that traditional therapeutic methods are not suitable for all patients, additionally, this type of ulcers have high amounts of metalloproteinases (MPMs), which is not allows the formation of matrix that leads to tissue healing.Modalidad Presencialapplication/pdfspahttp://creativecommons.org/licenses/by-nc-nd/2.5/co/Abierto (Texto Completo)Atribución-NoComercial-SinDerivadas 2.5 Colombiahttp://purl.org/coar/access_right/c_abf2Diseño de una biotinta tipo hidrogel a base de polietilenglicol diacrilado con plasma rico en plaquetas, dirigida a la fabricación de apósitos para úlceras crónicas de pie diabético por bioimpresión 3DDesign of a hydrogel-type bioink based on diacrylated polyethylene glycol with platelet-rich plasma, aimed at the manufacture of dressings for chronic diabetic foot ulcers by 3D bioprintingResearch reportinfo:eu-repo/semantics/workingPaperInforme de investigaciónhttp://purl.org/coar/resource_type/c_18wshttp://purl.org/coar/resource_type/c_8042info:eu-repo/semantics/acceptedVersionhttp://purl.org/redcol/resource_type/IFIUniversidad Autónoma de Bucaramanga UNABFacultad Ciencias de la SaludMetabolism disordersPlatelet rich plasmaBloodThree-dimensional image in designBioinkDiabetic footDiabetesTrastornos del metabolismoPlasma rico en plaquetasSangreImagen tridimensional en diseñoBiotintaPie diabéticoFederation, I. 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Advanced Materials 32, 1902516, doi:10.1002/adma.201902516 (2020)ORIGINALInforme.pdfInforme.pdfInformeapplication/pdf576694https://repository.unab.edu.co/bitstream/20.500.12749/21358/1/Informe.pdffba13de89cf64dffe0d5c518bfc8e7daMD51open accessActa de Incio_Proyecto de Investigacion.pdfActa de Incio_Proyecto de Investigacion.pdfLicenciaapplication/pdf1717414https://repository.unab.edu.co/bitstream/20.500.12749/21358/2/Acta%20de%20Incio_Proyecto%20de%20Investigacion.pdf6983461587c45dad8eadf389c10aa050MD52metadata only accessLICENSElicense.txtlicense.txttext/plain; charset=utf-8829https://repository.unab.edu.co/bitstream/20.500.12749/21358/3/license.txt3755c0cfdb77e29f2b9125d7a45dd316MD53open accessTHUMBNAILInforme.pdf.jpgInforme.pdf.jpgIM Thumbnailimage/jpeg9506https://repository.unab.edu.co/bitstream/20.500.12749/21358/4/Informe.pdf.jpg053a1e291879887bdd9879c9c4f5ffceMD54open accessActa de Incio_Proyecto de Investigacion.pdf.jpgActa de Incio_Proyecto de Investigacion.pdf.jpgIM Thumbnailimage/jpeg11330https://repository.unab.edu.co/bitstream/20.500.12749/21358/5/Acta%20de%20Incio_Proyecto%20de%20Investigacion.pdf.jpg090d0a1ecfa432dee03a7f04b4e5ac56MD55metadata only access20.500.12749/21358oai:repository.unab.edu.co:20.500.12749/213582023-08-23 22:00:33.948open accessRepositorio Institucional | Universidad Autónoma de Bucaramanga - UNABrepositorio@unab.edu.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