Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha

Objetivo. Evaluar la asociación entre patrones de sueño y el cambio en la presión arterial (PA) e incidencia de hipertensión arterial en el contexto de la cohorte CHICAMOCHA. Métodos. El presente corresponde al análisis secundario del estudio de cohorte prospectiva CHICAMOCHA (Cardiovascular Health...

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Autores:
Vargas Ordóñez, Jhon Edgar
Tipo de recurso:
Fecha de publicación:
2017
Institución:
Universidad Autónoma de Bucaramanga - UNAB
Repositorio:
Repositorio UNAB
Idioma:
spa
OAI Identifier:
oai:repository.unab.edu.co:20.500.12749/1728
Acceso en línea:
http://hdl.handle.net/20.500.12749/1728
Palabra clave:
Blood pressure
High blood pressure
Adiposity
Dream
Medicine
Internal medicine
Investigations
Complications
Patients
Prevention and control
Dream architecture
Obstructive sleep apnea syndrome (OSAS)
Cardiovascular disease
Risk of hypertensive disease
Presión arterial
Hipertensión arterial
Adiposidad
Sueño
Medicina
Medicina interna
Investigaciones
Complicaciones
Pacientes
Prevención y control
Arquitectura del sueño
Síndrome de apnea obstructiva del sueño (SAOS)
Enfermedad cardiovascular
Riesgo de enfermedad hipertensiva
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openAccess
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http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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dc.title.spa.fl_str_mv Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha
dc.title.translated.eng.fl_str_mv Determination of the association between sleep patterns and the change in blood pressure in adults of the general population: results of the Chicamocha cohort
title Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha
spellingShingle Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha
Blood pressure
High blood pressure
Adiposity
Dream
Medicine
Internal medicine
Investigations
Complications
Patients
Prevention and control
Dream architecture
Obstructive sleep apnea syndrome (OSAS)
Cardiovascular disease
Risk of hypertensive disease
Presión arterial
Hipertensión arterial
Adiposidad
Sueño
Medicina
Medicina interna
Investigaciones
Complicaciones
Pacientes
Prevención y control
Arquitectura del sueño
Síndrome de apnea obstructiva del sueño (SAOS)
Enfermedad cardiovascular
Riesgo de enfermedad hipertensiva
title_short Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha
title_full Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha
title_fullStr Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha
title_full_unstemmed Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha
title_sort Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha
dc.creator.fl_str_mv Vargas Ordóñez, Jhon Edgar
dc.contributor.advisor.spa.fl_str_mv Herrera Galindo, Víctor Mauricio
dc.contributor.author.spa.fl_str_mv Vargas Ordóñez, Jhon Edgar
dc.contributor.cvlac.*.fl_str_mv https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000068020
dc.contributor.googlescholar.*.fl_str_mv https://scholar.google.es/citations?hl=es&user=ay0xprEAAAAJ
dc.contributor.orcid.*.fl_str_mv https://orcid.org/0000-0002-6295-1640
https://orcid.org/0000-0002-8939-6771
dc.contributor.scopus.*.fl_str_mv https://www.scopus.com/authid/detail.uri?authorId=55402953400
dc.contributor.researchgroup.spa.fl_str_mv Grupo de Investigación en Cardiología Preventiva
Grupo de Investigaciones Clínicas
dc.subject.keywords.eng.fl_str_mv Blood pressure
High blood pressure
Adiposity
Dream
Medicine
Internal medicine
Investigations
Complications
Patients
Prevention and control
Dream architecture
Obstructive sleep apnea syndrome (OSAS)
Cardiovascular disease
Risk of hypertensive disease
topic Blood pressure
High blood pressure
Adiposity
Dream
Medicine
Internal medicine
Investigations
Complications
Patients
Prevention and control
Dream architecture
Obstructive sleep apnea syndrome (OSAS)
Cardiovascular disease
Risk of hypertensive disease
Presión arterial
Hipertensión arterial
Adiposidad
Sueño
Medicina
Medicina interna
Investigaciones
Complicaciones
Pacientes
Prevención y control
Arquitectura del sueño
Síndrome de apnea obstructiva del sueño (SAOS)
Enfermedad cardiovascular
Riesgo de enfermedad hipertensiva
dc.subject.lemb.spa.fl_str_mv Presión arterial
Hipertensión arterial
Adiposidad
Sueño
Medicina
Medicina interna
Investigaciones
Complicaciones
Pacientes
Prevención y control
dc.subject.proposal.none.fl_str_mv Arquitectura del sueño
Síndrome de apnea obstructiva del sueño (SAOS)
Enfermedad cardiovascular
Riesgo de enfermedad hipertensiva
description Objetivo. Evaluar la asociación entre patrones de sueño y el cambio en la presión arterial (PA) e incidencia de hipertensión arterial en el contexto de la cohorte CHICAMOCHA. Métodos. El presente corresponde al análisis secundario del estudio de cohorte prospectiva CHICAMOCHA (Cardiovascular Health and Collaboration to Assess the Markers and Outcomes in Chagas disease), conducido en adultos jóvenes, seronegativos para infecciones transmisibles por vía transfusional y asintomáticos para enfermedad cardiovascular. Se consideró como la visita de referencia a la primera de seguimiento de la cohorte (2003-2006) en la que se administró un cuestionario de sueño (incluyendo aspectos del nórdico y Pittsburgh) y se realizaron mediciones antropométricas y de PA. Los participantes fueron seguidos después de una mediana de 10 años para repetir mediciones de PA y determinar la incidencia de hipertensión arterial definida como PA sistólica/diastólica ≥140/90 mmHg o tratamiento antihipertensivo. Se emplearon métodos de regresión lineal y logística múltiple para estimar las asociaciones de interés, ajustando por covariables. Resultados. Evaluamos 705 participantes (edad media=39.6 años; 64% hombres; 75% estrato socioeconómico 1-3) que asistieron tanto a la primera como la segunda visita de seguimiento después de 9.5 años (rango intercuartílico: 9.1 - 9.9 años). Los hallazgos más frecuentes con relación al sueño fueron el despertar nocturno (63.3%), el ronquido (60.7%) y problemas para conciliar el sueño (22.9%). La incidencia de hipertensión arterial fue 15.2% (IC95%: 12.6 – 18.0) hallándose que una duración entre 7.5 – 8.0 horas/día se asociaba al menor riesgo de desarrollar esta condición. Entre los atributos del sueño, solo el reporte de ronquido se asoció independientemente a un cambio en la presión arterial sistólica, pero no diastólica, de 2.2 mmHg (IC95%: 0.28, 4.12). No se evidenció interacción entre adiposidad y atributos del sueño. Conclusión. El auto-reporte de ronquido está asociado a incrementos independientes y estadísticamente significativos de la presión arterial sistólica mientras que una duración promedio del sueño principal entre 7.5 – 8.0 horas/día se asocia al menor riesgo de hipertensión arterial.
publishDate 2017
dc.date.issued.none.fl_str_mv 2017
dc.date.accessioned.none.fl_str_mv 2020-06-26T19:59:52Z
dc.date.available.none.fl_str_mv 2020-06-26T19:59:52Z
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.local.spa.fl_str_mv Tesis
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dc.identifier.instname.spa.fl_str_mv instname:Universidad Autónoma de Bucaramanga - UNAB
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional UNAB
url http://hdl.handle.net/20.500.12749/1728
identifier_str_mv instname:Universidad Autónoma de Bucaramanga - UNAB
reponame:Repositorio Institucional UNAB
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.references.spa.fl_str_mv Vargas Ordóñez, Jhon Edgar (2017). Determinación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte Chicamocha. Floridablanca (Santander, Colombia) : Universidad Autónoma de Bucaramanga UNAB
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spelling Herrera Galindo, Víctor Mauricio82736c90-93c9-4f26-86c7-0c8ae52dea2f-1Vargas Ordóñez, Jhon Edgar36f7e0e3-b227-4ba5-bb28-984df6bf0b77-1https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000068020https://scholar.google.es/citations?hl=es&user=ay0xprEAAAAJhttps://orcid.org/0000-0002-6295-1640https://orcid.org/0000-0002-8939-6771https://www.scopus.com/authid/detail.uri?authorId=55402953400Grupo de Investigación en Cardiología PreventivaGrupo de Investigaciones Clínicas2020-06-26T19:59:52Z2020-06-26T19:59:52Z2017http://hdl.handle.net/20.500.12749/1728instname:Universidad Autónoma de Bucaramanga - UNABreponame:Repositorio Institucional UNABObjetivo. Evaluar la asociación entre patrones de sueño y el cambio en la presión arterial (PA) e incidencia de hipertensión arterial en el contexto de la cohorte CHICAMOCHA. Métodos. El presente corresponde al análisis secundario del estudio de cohorte prospectiva CHICAMOCHA (Cardiovascular Health and Collaboration to Assess the Markers and Outcomes in Chagas disease), conducido en adultos jóvenes, seronegativos para infecciones transmisibles por vía transfusional y asintomáticos para enfermedad cardiovascular. Se consideró como la visita de referencia a la primera de seguimiento de la cohorte (2003-2006) en la que se administró un cuestionario de sueño (incluyendo aspectos del nórdico y Pittsburgh) y se realizaron mediciones antropométricas y de PA. Los participantes fueron seguidos después de una mediana de 10 años para repetir mediciones de PA y determinar la incidencia de hipertensión arterial definida como PA sistólica/diastólica ≥140/90 mmHg o tratamiento antihipertensivo. Se emplearon métodos de regresión lineal y logística múltiple para estimar las asociaciones de interés, ajustando por covariables. Resultados. Evaluamos 705 participantes (edad media=39.6 años; 64% hombres; 75% estrato socioeconómico 1-3) que asistieron tanto a la primera como la segunda visita de seguimiento después de 9.5 años (rango intercuartílico: 9.1 - 9.9 años). Los hallazgos más frecuentes con relación al sueño fueron el despertar nocturno (63.3%), el ronquido (60.7%) y problemas para conciliar el sueño (22.9%). La incidencia de hipertensión arterial fue 15.2% (IC95%: 12.6 – 18.0) hallándose que una duración entre 7.5 – 8.0 horas/día se asociaba al menor riesgo de desarrollar esta condición. Entre los atributos del sueño, solo el reporte de ronquido se asoció independientemente a un cambio en la presión arterial sistólica, pero no diastólica, de 2.2 mmHg (IC95%: 0.28, 4.12). No se evidenció interacción entre adiposidad y atributos del sueño. Conclusión. El auto-reporte de ronquido está asociado a incrementos independientes y estadísticamente significativos de la presión arterial sistólica mientras que una duración promedio del sueño principal entre 7.5 – 8.0 horas/día se asocia al menor riesgo de hipertensión arterial.1 DESCRIPCIÓN DEL PROYECTO ...................................................................... 7 1.1 PLANTEAMIENTO Y JUSTIFICACIÓN DEL PROBLEMA ............................... 7 2 MARCO TEÓRICO Y ESTADO DEL ARTE ....................................................... 8 3 OBJETIVOS ..................................................................................................... 12 3.1 OBJETIVO GENERAL ................................................................................... 12 3.2 OBJETIVOS ESPECÍFICOS .......................................................................... 12 4 METODOLOGÍA PROPUESTA ........................................................................ 13 4.1 DISEÑO ......................................................................................................... 13 4.2 UNIVERSO .................................................................................................... 13 4.3 POBLACIÓN OBJETO ................................................................................... 13 4.4 MUESTRA/MUESTREO ................................................................................ 13 4.5 CRITERIOS DE INCLUSIÓN Y EXCLUSIÓN ................................................ 13 4.6 VARIABLES ................................................................................................... 14 4.7 OBTENCIÓN DE LA INFORMACIÓN ............................................................ 14 4.8 PLAN DE ANÁLISIS ESTADÍSTICO .............................................................. 15 4.9 CONSIDERACIONES ÉTICAS ...................................................................... 16 5 RESULTADOS ................................................................................................. 17 6 DISCUSIÓN...................................................................................................... 19 7 CONCLUSIÓN .................................................................................................. 21 8 BIBLIOGRAFÍA ................................................................................................. 22EspecializaciónObjective. To evaluate the association between sleep patterns and the change in blood pressure (BP) and incidence of arterial hypertension in the context of the CHICAMOCHA cohort. Methods. This corresponds to the secondary analysis of the prospective cohort study CHICAMOCHA (Cardiovascular Health and Collaboration to Assess the Markers and Outcomes in Chagas disease), conducted in young adults, seronegative for transfusionally transmitted infections and asymptomatic for cardiovascular disease. The first follow-up visit of the cohort (2003-2006) was considered as the reference visit, in which a sleep questionnaire was administered (including aspects of Nordic and Pittsburgh) and anthropometric and BP measurements were performed. Participants were followed up after a median of 10 years to repeat BP measurements and determine the incidence of arterial hypertension defined as systolic / diastolic BP ≥140 / 90 mmHg or antihypertensive treatment. Linear regression and multiple logistic methods were used to estimate the associations of interest, adjusting for covariates. Results. We evaluated 705 participants (mean age = 39.6 years; 64% men; 75% socioeconomic stratum 1-3) who attended both the first and the second follow-up visit after 9.5 years (interquartile range: 9.1 - 9.9 years). The most frequent findings in relation to sleep were night waking (63.3%), snoring (60.7%) and problems falling asleep (22.9%). The incidence of arterial hypertension was 15.2% (95% CI: 12.6 - 18.0), finding that a duration between 7.5 - 8.0 hours / day was associated with a lower risk of developing this condition. Among the sleep attributes, only the snoring report was independently associated with a change in systolic, but not diastolic, blood pressure of 2.2 mmHg (95% CI: 0.28, 4.12). There was no evidence of interaction between adiposity and sleep attributes. Conclusion. Self-reported snoring is associated with independent and statistically significant increases in systolic blood pressure, while an average duration of main sleep between 7.5 - 8.0 hours / day is associated with a lower risk of arterial hypertension.Modalidad Presencialapplication/pdfspahttp://creativecommons.org/licenses/by-nc-nd/2.5/co/Abierto (Texto Completo)info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Atribución-NoComercial-SinDerivadas 2.5 ColombiaDeterminación de la asociación entre patrones del sueño y el cambio de la presión arterial en adultos de la población general: resultados de la cohorte ChicamochaDetermination of the association between sleep patterns and the change in blood pressure in adults of the general population: results of the Chicamocha cohortEspecialista en Medicina InternaFloridablanca (Santander, Colombia)UNAB Campus BucaramangaUniversidad Autónoma de Bucaramanga UNABFacultad Ciencias de la SaludEspecialización en Medicina Internainfo:eu-repo/semantics/masterThesisTesishttp://purl.org/redcol/resource_type/TMBlood pressureHigh blood pressureAdiposityDreamMedicineInternal medicineInvestigationsComplicationsPatientsPrevention and controlDream architectureObstructive sleep apnea syndrome (OSAS)Cardiovascular diseaseRisk of hypertensive diseasePresión arterialHipertensión arterialAdiposidadSueñoMedicinaMedicina internaInvestigacionesComplicacionesPacientesPrevención y controlArquitectura del sueñoSíndrome de apnea obstructiva del sueño (SAOS)Enfermedad cardiovascularRiesgo de enfermedad hipertensivaVargas Ordóñez, Jhon Edgar (2017). 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Rev Neurol 2005; 40 150-155. 2005;40(3):150–5.ORIGINAL2017_Tesis_Jhon_Edgar_Vargas_Ordoñez.pdf2017_Tesis_Jhon_Edgar_Vargas_Ordoñez.pdfTesisapplication/pdf1567271https://repository.unab.edu.co/bitstream/20.500.12749/1728/1/2017_Tesis_Jhon_Edgar_Vargas_Ordo%c3%b1ez.pdf3a1d6aee6f2557cdb5ac8fa9c5d44e08MD51open access2017_Licencia_Jhon_Edgar_Vargas_Ordoñez.pdf2017_Licencia_Jhon_Edgar_Vargas_Ordoñez.pdfLicenciaapplication/pdf133139https://repository.unab.edu.co/bitstream/20.500.12749/1728/2/2017_Licencia_Jhon_Edgar_Vargas_Ordo%c3%b1ez.pdf4804d0f2a672af7108cc099fec801edaMD52metadata only accessTHUMBNAIL2017_Tesis_Jhon_Edgar_Vargas_Ordoñez.pdf.jpg2017_Tesis_Jhon_Edgar_Vargas_Ordoñez.pdf.jpgIM Thumbnailimage/jpeg4914https://repository.unab.edu.co/bitstream/20.500.12749/1728/3/2017_Tesis_Jhon_Edgar_Vargas_Ordo%c3%b1ez.pdf.jpg28c9d65fddb851f45f5f3dd1d8f99fa6MD53open access2017_Licencia_Jhon_Edgar_Vargas_Ordoñez.pdf.jpg2017_Licencia_Jhon_Edgar_Vargas_Ordoñez.pdf.jpgIM Thumbnailimage/jpeg11355https://repository.unab.edu.co/bitstream/20.500.12749/1728/4/2017_Licencia_Jhon_Edgar_Vargas_Ordo%c3%b1ez.pdf.jpg5e7ab4a1a2b8f064cb93469a5f2c31c9MD54metadata only access20.500.12749/1728oai:repository.unab.edu.co:20.500.12749/17282024-01-21 10:26:20.912open accessRepositorio Institucional | Universidad Autónoma de Bucaramanga - UNABrepositorio@unab.edu.co

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