Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen

La hiperplasia prostática benigna (HPB) es un diagnóstico histológico de proliferación de músculo liso y células epiteliales en la zona transicional. Tiene una prevalencia del 50% en hombres de 50 años y hasta 80% a los 80 años. La principal manifestación clínica son los síntomas del tracto urinario...

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Autores:
Sandoval Ojeda, Juan Manuel
Tipo de recurso:
Fecha de publicación:
2022
Institución:
Universidad Autónoma de Bucaramanga - UNAB
Repositorio:
Repositorio UNAB
Idioma:
spa
OAI Identifier:
oai:repository.unab.edu.co:20.500.12749/16888
Acceso en línea:
http://hdl.handle.net/20.500.12749/16888
Palabra clave:
Medical sciences
Health sciences
Urology
Medicine
Thulium
ThuVep
huVap
Open prostatectomy
Prostate diseases
Hyperplasia
Cell pathology
Urethroscopy
Urología
Medicina
Ciencias médicas
Enfermedades de la próstata
Hiperplasia
Patología celular
Uretroscopia
Ciencias de la salud
HPB
Prostatectomía abierta
Láser
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License
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
id UNAB2_279b55a2cb26cdb020b10496213b8032
oai_identifier_str oai:repository.unab.edu.co:20.500.12749/16888
network_acronym_str UNAB2
network_name_str Repositorio UNAB
repository_id_str
dc.title.spa.fl_str_mv Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen
dc.title.translated.spa.fl_str_mv Vaporesection/ vapoenucleation of the prostate with thulium laser versus open prostatectomy in high-volume prostates
title Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen
spellingShingle Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen
Medical sciences
Health sciences
Urology
Medicine
Thulium
ThuVep
huVap
Open prostatectomy
Prostate diseases
Hyperplasia
Cell pathology
Urethroscopy
Urología
Medicina
Ciencias médicas
Enfermedades de la próstata
Hiperplasia
Patología celular
Uretroscopia
Ciencias de la salud
HPB
Prostatectomía abierta
Láser
title_short Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen
title_full Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen
title_fullStr Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen
title_full_unstemmed Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen
title_sort Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumen
dc.creator.fl_str_mv Sandoval Ojeda, Juan Manuel
dc.contributor.advisor.none.fl_str_mv Salazar Rey, Milton
Camacho López, Paul Anthony
dc.contributor.author.none.fl_str_mv Sandoval Ojeda, Juan Manuel
dc.contributor.cvlac.spa.fl_str_mv Salazar Rey, Milton [0001489804]
Camacho López, Paul Anthony [0000323578]
dc.contributor.googlescholar.spa.fl_str_mv Camacho López, Paul Anthony [u8d7_QAAAAJ]
dc.contributor.orcid.spa.fl_str_mv Salazar Rey, Milton [0000-0002-1316-4149]
Camacho López, Paul Anthony [0000-0002-6233-9582]
dc.contributor.scopus.spa.fl_str_mv Camacho López, Paul Anthony [16047325700]
dc.contributor.researchgate.spa.fl_str_mv Salazar Rey, Milton [Milton-Salazar-Rey-31568627]
Camacho López, Paul Anthony [Paul_Camacho_Lopez]
dc.contributor.apolounab.none.fl_str_mv Camacho López, Paul Anthony [paul-anthony-camacho-lópez]
dc.contributor.linkedin.none.fl_str_mv Camacho López, Paul Anthony [paulcamachomdepi]
dc.subject.keywords.spa.fl_str_mv Medical sciences
Health sciences
Urology
Medicine
Thulium
ThuVep
huVap
Open prostatectomy
Prostate diseases
Hyperplasia
Cell pathology
Urethroscopy
topic Medical sciences
Health sciences
Urology
Medicine
Thulium
ThuVep
huVap
Open prostatectomy
Prostate diseases
Hyperplasia
Cell pathology
Urethroscopy
Urología
Medicina
Ciencias médicas
Enfermedades de la próstata
Hiperplasia
Patología celular
Uretroscopia
Ciencias de la salud
HPB
Prostatectomía abierta
Láser
dc.subject.lemb.spa.fl_str_mv Urología
Medicina
Ciencias médicas
Enfermedades de la próstata
Hiperplasia
Patología celular
Uretroscopia
dc.subject.proposal.spa.fl_str_mv Ciencias de la salud
HPB
Prostatectomía abierta
Láser
description La hiperplasia prostática benigna (HPB) es un diagnóstico histológico de proliferación de músculo liso y células epiteliales en la zona transicional. Tiene una prevalencia del 50% en hombres de 50 años y hasta 80% a los 80 años. La principal manifestación clínica son los síntomas del tracto urinario inferior (SUOB), alcanzando una prevalencia de 45.2%. La resección transuretral de próstata (RTUP) se consideró el Gold estándar en próstatas de bajo volumen (< 80 cc) y para próstatas de alto volumen (> de 80 cc) fue la prostatectomía abierta (PA), con altas tasas de efectividad y un margen aceptable de seguridad. En la actualidad, existen alternativas endoscópicas con tecnología Láser (Holmium, Green laser, Thulium). En la población colombiana, no se cuenta con datos de efectividad de una técnica frente a otra en pacientes en próstatas de alto volumen. El objetivo del estudio es analizar la efectividad, costos y desenlaces de los pacientes sometidos a procedimientos endoscópicos Laser vs abierto.
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2022-07-11T18:26:54Z
dc.date.available.none.fl_str_mv 2022-07-11T18:26:54Z
dc.date.issued.none.fl_str_mv 2022-06-14
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.local.spa.fl_str_mv Tesis
dc.type.hasversion.none.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.redcol.none.fl_str_mv http://purl.org/redcol/resource_type/TM
status_str acceptedVersion
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12749/16888
dc.identifier.instname.spa.fl_str_mv instname:Universidad Autónoma de Bucaramanga - UNAB
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional UNAB
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url http://hdl.handle.net/20.500.12749/16888
identifier_str_mv instname:Universidad Autónoma de Bucaramanga - UNAB
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language spa
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spelling Salazar Rey, Milton151865d4-ec9d-43c1-8115-77dcc2e7b80aCamacho López, Paul Anthonye46d0c19-2faf-4964-80c2-bc6b94bb4127Sandoval Ojeda, Juan Manuel65eb7dd8-d456-4d38-aa12-80b93cd7e852Salazar Rey, Milton [0001489804]Camacho López, Paul Anthony [0000323578]Camacho López, Paul Anthony [u8d7_QAAAAJ]Salazar Rey, Milton [0000-0002-1316-4149]Camacho López, Paul Anthony [0000-0002-6233-9582]Camacho López, Paul Anthony [16047325700]Salazar Rey, Milton [Milton-Salazar-Rey-31568627]Camacho López, Paul Anthony [Paul_Camacho_Lopez]Camacho López, Paul Anthony [paul-anthony-camacho-lópez]Camacho López, Paul Anthony [paulcamachomdepi]Floridablanca (Santander, Colombia)2017-2020UNAB Campus Bucaramanga2022-07-11T18:26:54Z2022-07-11T18:26:54Z2022-06-14http://hdl.handle.net/20.500.12749/16888instname:Universidad Autónoma de Bucaramanga - UNABreponame:Repositorio Institucional UNABrepourl:https://repository.unab.edu.coLa hiperplasia prostática benigna (HPB) es un diagnóstico histológico de proliferación de músculo liso y células epiteliales en la zona transicional. Tiene una prevalencia del 50% en hombres de 50 años y hasta 80% a los 80 años. La principal manifestación clínica son los síntomas del tracto urinario inferior (SUOB), alcanzando una prevalencia de 45.2%. La resección transuretral de próstata (RTUP) se consideró el Gold estándar en próstatas de bajo volumen (< 80 cc) y para próstatas de alto volumen (> de 80 cc) fue la prostatectomía abierta (PA), con altas tasas de efectividad y un margen aceptable de seguridad. En la actualidad, existen alternativas endoscópicas con tecnología Láser (Holmium, Green laser, Thulium). En la población colombiana, no se cuenta con datos de efectividad de una técnica frente a otra en pacientes en próstatas de alto volumen. El objetivo del estudio es analizar la efectividad, costos y desenlaces de los pacientes sometidos a procedimientos endoscópicos Laser vs abierto.LISTA DE TABLAS 6 LISTA DE FIGURAS 7 LISTA DE ANEXOS 8 GLOSARIO 9 RESUMEN 10 INTRODUCCIÓN 14 1. DESCRIPCIÓN DEL PROYECTO 15 1.1 Planteamiento del problema y justificación 15 1.2 Pregunta de investigación 16 2.1. Marco Teórico 17 2.2. Estado del Arte 22 2.3. Objetivos 25 2.4.1. Objetivo general 25 2.4.2. Objetivos específicos 25 2.5. Metodología 26 2.5.1. Diseño 26 2.5.2. Universo 26 2.5.3. Población Objeto 26 2.5.4. Criterios de elegibilidad 26 2.5.4.1. Criterios de Inclusión 26 2.5.4.2. Criterios de Exclusión 26 2.5.5. Descripción del procedimiento 27 5 2.5.6. plan de análisis de datos 27 3. CONSIDERACIONES ÉTICAS 29 4. RESULTADOS 31 5. DISCUSIÓN 39 6. CONCLUSIONES 42 7. REFERENCIAS BIBLIOGRÁFICAS 43EspecializaciónBenign prostatic hyperplasia (BPH) is a histological diagnosis of smooth muscle and epithelial cell proliferation in the transitional zone. It has a prevalence of 50% in men aged 50 years and up to 80% at the age of 80 years. The main clinical manifestation is lower urinary tract symptoms (LUTS), reaching a prevalence of 45.2%. Transurethral resection of the prostate (TURP) was considered the Gold standard in low-volume prostates (< 80 cc) and for high-volume prostates (> 80 cc) it was open prostatectomy (OP), with high effectiveness rates and an acceptable margin of safety. Currently, there are endoscopic alternatives with laser technology (Holmium, Green laser, Thulium). In the Colombian population, there is no data on the effectiveness of one technique versus another in patients with high volume prostates. The objective of the study is to analyze the effectiveness, costs and outcomes of patients submitted to endoscopic Laser vs. open procedures.Modalidad Presencialapplication/pdfspahttp://creativecommons.org/licenses/by-nc-nd/2.5/co/Abierto (Texto Completo)Atribución-NoComercial-SinDerivadas 2.5 Colombiahttp://purl.org/coar/access_right/c_abf2Vaporesección/ vapoenucleación de próstata con láser thulium frente a prostatectomía abierta en próstatas de alto volumenVaporesection/ vapoenucleation of the prostate with thulium laser versus open prostatectomy in high-volume prostatesEspecialista en UrologíaUniversidad Autónoma de Bucaramanga UNABFacultad Ciencias de la SaludEspecialización en Urologíainfo:eu-repo/semantics/masterThesisTesisinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/redcol/resource_type/TMMedical sciencesHealth sciencesUrologyMedicineThuliumThuVephuVapOpen prostatectomyProstate diseasesHyperplasiaCell pathologyUrethroscopyUrologíaMedicinaCiencias médicasEnfermedades de la próstataHiperplasiaPatología celularUretroscopiaCiencias de la saludHPBProstatectomía abiertaLáser1. Bartsch, G., Müller, H. R., Oberholzer, M., & Rohr, H. P. (1979). Light microscopic stereological analysis of the normal human prostate and of benign prostatic hyperplasia. The Journal of Urology, 122(4), 487–491. https://doi.org/10.1016/s0022-5347(17)56476-2. Vuichoud, C., & Loughlin, K. R. (2015). Benign prostatic hyperplasia: epidemiology, economics and evaluation. The Canadian journal of urology, 22 Suppl 1, 1–6.3. Bartsch, G., Müller, H. R., Oberholzer, M., & Rohr, H. P. (1979). Light microscopic stereological analysis of the normal human prostate and of benign prostatic hyperplasia. The Journal of Urology, 122(4), 487– 491. https://doi.org/10.1016/s0022-5347(17)56476-94. Irwin, D. E., Kopp, Z. S., Agatep, B., Milsom, I., & Abrams, P. (2011). Worldwide prevalence estimates of lower urinary tract symptoms, overactive bladder, urinary incontinence and bladder outlet obstruction. BJU international, 108(7), 1132–1138. https://doi.org/10.1111/j.1464410X.2010.09993.x5. McConnell, J. 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The Urologic Clinics of North America, 22(2), 237–246. https://pubmed.ncbi.nlm.nih.gov/7539172/11. Isaacs, J. T., & Coffey, D. S. (1989). Etiology and disease process of benign prostatic hyperplasia. The Prostate. Supplement, 2, 33–50. https://doi.org/10.1002/pros.299015050612. Tanagho, E. A., & McAninch, J. W. (2008). Smith’s General Urology (17a ed.). McGraw-Hill Medical13. McVary, K. T. (2006). BPH: epidemiology and comorbidities. The American Journal of Managed Care, 12(5 Suppl), S122-8. https://pubmed.ncbi.nlm.nih.gov/16613526/14. Castro Muñoz, Juan Carlos, & Gonzáles Encinales, César, & Rozo Maragua, Luis Ernesto, & Reyes Calderón, Jesús Antonio (2007). Estudio de Fármacovigilancia en pacientes con Hiperplasia Prostática Benigna (HPB) sintomática tratados con Tamsulosina 0.4 mg en 8 ciudades de Colombia. Revista Urología Colombiana, XVI(1),107117.[fecha de Consulta 8 de Junio de 2022]. ISSN: 0120-789X. Disponible en: https://www.redalyc.org/articulo.oa?id=14912046801415. 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Does this man with lower urinary tract symptoms have bladder outlet obstruction?: The Rational Clinical Examination: a systematic review. JAMA, 312(5), 535– 542. https://doi.org/10.1001/jama.2014.555518. Barry, M. J., Fowler, F. J., Jr, O'Leary, M. P., Bruskewitz, R. C., Holtgrewe, H. L., Mebust, W. K., & Cockett, A. T. (1992). The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. The Journal of urology, 148(5), 1549–1564. https://doi.org/10.1016/s0022-5347(17)36966-519. Sirls, L. T., Kirkemo, A. K., & Jay, J. (1996). Lack of correlation of the American Urological Association Symptom 7 Index with urodynamic bladder outlet obstruction. Neurourology and urodynamics, 15(5), 447– 457. https://doi.org/10.1002/(SICI)1520-6777(1996)15:520. Donovan, J. L., Peters, T. J., Abrams, P., Brookes, S. T., de aa Rosette, J. J., & Schäfer, W. (2000). Scoring the short form ICSmaleSF questionnaire. 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Herrmann, T. R., Liatsikos, E. N., Nagele, U., Traxer, O., Merseburger, A. S., & EAU Guidelines Panel on Lasers, Technologies (2012). EAU guidelines on laser technologies. European urology, 61(4), 783–795. https://doi.org/10.1016/j.eururo.2012.01.01029. Smith, R. D., & Patel, A. (2011). Transurethral resection of the prostate revisited and updated. Current opinion in urology, 21(1), 36–41. https://doi.org/10.1097/MOU.0b013e328341145530. Lourenco, T., Armstrong, N., N'Dow, J., Nabi, G., Deverill, M., Pickard, R., Vale, L., MacLennan, G., Fraser, C., McClinton, S., Wong, S., Coutts, A., Mowatt, G., & Grant, A. (2008). Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement. Health technology assessment (Winchester, England), 12(35), iii–515. https://doi.org/10.3310/hta1235031. Reich, O., Gratzke, C., Bachmann, A., Seitz, M., Schlenker, B., Hermanek, P., Lack, N., Stief, C. G., & Urology Section of the Bavarian Working Group for Quality Assurance (2008). Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. The Journal of urology, 180(1), 246–249. https://doi.org/10.1016/j.juro.2008.03.05832. Cornu, J. N., Ahyai, S., Bachmann, A., de la Rosette, J., Gilling, P., Gratzke, C., McVary, K., Novara, G., Woo, H., & Madersbacher, S. (2015). A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update. European urology, 67(6), 1066–1096. https://doi.org/10.1016/j.eururo.2014.06.01733. Nestler, S., Bach, T., Herrmann, T., Jutzi, S., Roos, F. C., Hampel, C., Thüroff, J. W., Thomas, C., & Neisius, A. (2019). Surgictreatment of large volume prostates: a matched pair analysis comparing the open, endoscopic (ThuVEP) and robotic approach. 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Journal of endourology19(1), 25–31. https://doi.org/10.1089/end.2005.19.2541. Li, M., Qiu, J., Hou, Q., Wang, D., Huang, W., Hu, C., Li, K., & Gao, X. (2015). Endoscopic enucleation versus open prostatectomy for treating large benign prostatic hyperplasia: a meta-analysis of randomized controlled trials. PloS one, 10(3), e0121265. https://doi.org/10.1371/journal.pone.012126542. Liu, C., Zheng, S., Li, H., & Xu, K. (2010). Transurethral enucleation and resection of prostate in patients with benign prostatic hyperplasia by plasma kinetics. The Journal of urology, 184(6), 2440– 2445. https://doi.org/10.1016/j.juro.2010.08.03743. Noble, S. M., Ahern, A. M., Worthington, J., Hashim, H., Taylor, H., Young, G. J., Brookes, S., Abrams, P., Johnson, L., Khan, R., Page, T., Swami, K. S., & Lane, J. A. (2020). 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World journal of urology, 33(4), 509–515. https://doi.org/10.1007/s00345-0141410-6THUMBNAIL2022_Tesis_Juan_Manuel_Sandoval.pdf.jpg2022_Tesis_Juan_Manuel_Sandoval.pdf.jpgIM Thumbnailimage/jpeg4523https://repository.unab.edu.co/bitstream/20.500.12749/16888/4/2022_Tesis_Juan_Manuel_Sandoval.pdf.jpg9da9b82d57bd4622586265931b79402cMD54open access2022_Licencia_Juan_Manuel_Sandoval.pdf.jpg2022_Licencia_Juan_Manuel_Sandoval.pdf.jpgIM Thumbnailimage/jpeg9676https://repository.unab.edu.co/bitstream/20.500.12749/16888/5/2022_Licencia_Juan_Manuel_Sandoval.pdf.jpg3ca08795c730cd1be37754bd1520f4dbMD55metadata only accessORIGINAL2022_Tesis_Juan_Manuel_Sandoval.pdf2022_Tesis_Juan_Manuel_Sandoval.pdfTesisapplication/pdf883621https://repository.unab.edu.co/bitstream/20.500.12749/16888/1/2022_Tesis_Juan_Manuel_Sandoval.pdfbe434f37635c819a531f5ee0a89cebd5MD51open access2022_Licencia_Juan_Manuel_Sandoval.pdf2022_Licencia_Juan_Manuel_Sandoval.pdfLicenciaapplication/pdf199991https://repository.unab.edu.co/bitstream/20.500.12749/16888/2/2022_Licencia_Juan_Manuel_Sandoval.pdf0188b930c513757f094236e68e5f0062MD52open accessLICENSElicense.txtlicense.txttext/plain; charset=utf-8829https://repository.unab.edu.co/bitstream/20.500.12749/16888/3/license.txt3755c0cfdb77e29f2b9125d7a45dd316MD53open access20.500.12749/16888oai:repository.unab.edu.co:20.500.12749/168882024-01-17 17:22:24.106open accessRepositorio Institucional | Universidad Autónoma de Bucaramanga - UNABrepositorio@unab.edu.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