An overview of mice models : a key for understanding subtypes of mania
ABSTRACT: Animal models have been broadly used inthe study of pathophysiology and molecular and neurochemical pathways in neuropsychiatric diseases. Different approaches have used both consanguineous and non-consanguineous mice models to model behavioral patterns associated with the maniac spectrum....
- Autores:
-
Cuartas Arias, Jorge Mauricio
Díaz Zuluaga, Ana María
López Jaramilo, Carlos
- Tipo de recurso:
- Review article
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/26215
- Acceso en línea:
- http://hdl.handle.net/10495/26215
- Palabra clave:
- Modelos Animales
Models, Animal
Trastorno Bipolar
Bipolar Disorder
Psicosis maniaco-depresiva
Manic-depressive psychoses
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-nd/2.5/co/
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An overview of mice models : a key for understanding subtypes of mania |
| dc.title.alternative.spa.fl_str_mv |
Una visión general de los modelos en ratón : una clave para la comprensión de los subtipos de manía |
| title |
An overview of mice models : a key for understanding subtypes of mania |
| spellingShingle |
An overview of mice models : a key for understanding subtypes of mania Modelos Animales Models, Animal Trastorno Bipolar Bipolar Disorder Psicosis maniaco-depresiva Manic-depressive psychoses |
| title_short |
An overview of mice models : a key for understanding subtypes of mania |
| title_full |
An overview of mice models : a key for understanding subtypes of mania |
| title_fullStr |
An overview of mice models : a key for understanding subtypes of mania |
| title_full_unstemmed |
An overview of mice models : a key for understanding subtypes of mania |
| title_sort |
An overview of mice models : a key for understanding subtypes of mania |
| dc.creator.fl_str_mv |
Cuartas Arias, Jorge Mauricio Díaz Zuluaga, Ana María López Jaramilo, Carlos |
| dc.contributor.author.none.fl_str_mv |
Cuartas Arias, Jorge Mauricio Díaz Zuluaga, Ana María López Jaramilo, Carlos |
| dc.subject.decs.none.fl_str_mv |
Modelos Animales Models, Animal Trastorno Bipolar Bipolar Disorder |
| topic |
Modelos Animales Models, Animal Trastorno Bipolar Bipolar Disorder Psicosis maniaco-depresiva Manic-depressive psychoses |
| dc.subject.lemb.none.fl_str_mv |
Psicosis maniaco-depresiva Manic-depressive psychoses |
| description |
ABSTRACT: Animal models have been broadly used inthe study of pathophysiology and molecular and neurochemical pathways in neuropsychiatric diseases. Different approaches have used both consanguineous and non-consanguineous mice models to model behavioral patterns associated with the maniac spectrum. However, the disadvantages of validating clinical and experimental protocols have hindered the replication of these studies. In this article, the advantages and disadvantages of using consanguineous lines and non-consanguineous stocks in mice animal models for the study of mania and its subtypes are discussed. Additionally, new experimental alternatives to advance the pathogenesis and pharmacogenetics of mania using animal models are proposed and analyzed. |
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2016 |
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2022-02-26T17:23:06Z |
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Cuartas Arias, J. M., Díaz Zuluaga, A. M., & López Jaramilo, C. (2016). An overview of mice models: a key for understanding subtypes of mania. International Journal of Psychological Research, 9(2), 113–123. https://doi.org/10.21500/20112084.2648 |
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2011-2084 |
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http://hdl.handle.net/10495/26215 |
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10.21500/20112084.2648 |
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2011-7922 |
| identifier_str_mv |
Cuartas Arias, J. M., Díaz Zuluaga, A. M., & López Jaramilo, C. (2016). An overview of mice models: a key for understanding subtypes of mania. International Journal of Psychological Research, 9(2), 113–123. https://doi.org/10.21500/20112084.2648 2011-2084 10.21500/20112084.2648 2011-7922 |
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http://hdl.handle.net/10495/26215 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Int. J. Psychol. Res. |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Universidad de San Buenaventura, Facultad de Psicología |
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Grupo de Investigación en Psiquiatría GIPSI |
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Medellín, Colombia |
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Universidad de Antioquia |
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Cuartas Arias, Jorge MauricioDíaz Zuluaga, Ana MaríaLópez Jaramilo, Carlos2022-02-26T17:23:06Z2022-02-26T17:23:06Z2016Cuartas Arias, J. M., Díaz Zuluaga, A. M., & López Jaramilo, C. (2016). An overview of mice models: a key for understanding subtypes of mania. International Journal of Psychological Research, 9(2), 113–123. https://doi.org/10.21500/20112084.26482011-2084http://hdl.handle.net/10495/2621510.21500/20112084.26482011-7922ABSTRACT: Animal models have been broadly used inthe study of pathophysiology and molecular and neurochemical pathways in neuropsychiatric diseases. Different approaches have used both consanguineous and non-consanguineous mice models to model behavioral patterns associated with the maniac spectrum. However, the disadvantages of validating clinical and experimental protocols have hindered the replication of these studies. In this article, the advantages and disadvantages of using consanguineous lines and non-consanguineous stocks in mice animal models for the study of mania and its subtypes are discussed. Additionally, new experimental alternatives to advance the pathogenesis and pharmacogenetics of mania using animal models are proposed and analyzed.RESUMEN: Los modelos animales se han utilizado ampliamente en el estudio de la fisiopatología y vías moleculares y neuroquímicos en enfermedades neuropsiquiátricas. Diferentes enfoques han utilizado modelos de ratones consanguíneos y no consanguíneos para modelar patrones de comportamiento asociados con el espectro maníaco. Sin embargo, las desventajas de la validación de los protocolos clínicos y experimentales han obstaculizado la replicación de estos estudios. En este artículo, se discuten las ventajas y desventajas del uso de líneas consanguíneas y no consanguíneas en modelos animales de ratones para el estudio de la manía y sus subtipos. Además, se proponen y analizan las nuevas alternativas experimentales para avanzar en la patogénesis y la farmacogenética de la manía utilizando modelos animales.COL002914710application/pdfengUniversidad de San Buenaventura, Facultad de PsicologíaGrupo de Investigación en Psiquiatría GIPSIMedellín, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTREVArtículo de revisiónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-nd/4.0/An overview of mice models : a key for understanding subtypes of maniaUna visión general de los modelos en ratón : una clave para la comprensión de los subtipos de maníaModelos AnimalesModels, AnimalTrastorno BipolarBipolar DisorderPsicosis maniaco-depresivaManic-depressive psychosesInt. J. Psychol. Res.International Journal of Psychological Research1131229Número especialCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8823http://bibliotecadigital.udea.edu.co/bitstream/10495/26215/2/license_rdfb88b088d9957e670ce3b3fbe2eedbc13MD52ORIGINALCuartasJorge_2016_ModelosanimalesTrastornoafectivobipolar.pdfCuartasJorge_2016_ModelosanimalesTrastornoafectivobipolar.pdfArtículo de revisiónapplication/pdf503064http://bibliotecadigital.udea.edu.co/bitstream/10495/26215/1/CuartasJorge_2016_ModelosanimalesTrastornoafectivobipolar.pdf7e2685c547f70af3e525c074656375faMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/26215/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/26215oai:bibliotecadigital.udea.edu.co:10495/262152022-02-26 12:23:07.034Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |