Posterior paralysis in a Holstein cow with Enzootic Bovine Leukosis

ABSTRACT: A 6 year-old Holstein cow was euthanized after a 3 week course of progressive paraplegia. In spite of the increasing difficulties to rise and walk, the animal remained bright, alert, afebrile and with good appetite throughout most of the clinical course. Complete blood counts, biochemical profiles and analysis of the cerebrospinal fluid were reported within normal limits. Antibody was detected for bovine leukaemia virus using an enzyme-linked immunosorbent assay, supporting a tentative diagnosis of bovine leukosis. Post-mortem examination revealed a localized form of lymphosarcoma with few 2-5 cm nodular tumors confined to the walls of the gastrointestinal tract, particularly in the abomasum. In addition, soft grey tumors were found within the vertebral canal surrounding the lumbar spinal cord and associated nerve roots. Microscopic examination revealed the nodular masses were composed of neoplastic lymphocytes. Mass in the lumbar vertebral canal had extradural neoplastic lymphocytes infiltrating connective tissues around the spinal cord and spinal nerve roots. Unlike the more common chronic and wasting presentation of the disease with widespread lymphadenopathy, the rapid progression of the disease to total paraplegia in this animal could be explained by the localized presence of tumors in the spinal canal.

• Autores: Pérez Montes, Juan Esteban; Giraldo Echeverri, Carlos Andrés; Villar Argaiz, David; Duque Muñoz, Leonardo; Pallarés Martínez, Francisco José; Schwartz, Kent
• Tipo de recurso: Article of journal
• Fecha de publicación: 2012
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: eng
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/8320
• Acceso en línea: http://hdl.handle.net/10495/8320
• Rights: openAccess
• License: Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)