Insuficiencia renal aguda inducida por rabdomiolisis
ABSTRACT: Acute renal failure is a frequent cause of morbidity and mortality in emergency, hospitalization and critical care services. In 15 % of cases it is due to rhabdomyolysis, in which there is breakdown of skeletal muscle with massive necrosis and leakage of muscle cell contents into the circu...
- Autores:
-
Nieto Ríos, John Fredy
Vega Miranda, Juliana
Serna Higuita, Lina María
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- spa
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/11581
- Acceso en línea:
- http://hdl.handle.net/10495/11581
- Palabra clave:
- Insuficiencia renal
Mioglobina
Músculo Esquelético
Rabdomiolisis
Necrosis Papilar Renal
- Rights
- openAccess
- License
- Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
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Insuficiencia renal aguda inducida por rabdomiolisis |
| title |
Insuficiencia renal aguda inducida por rabdomiolisis |
| spellingShingle |
Insuficiencia renal aguda inducida por rabdomiolisis Insuficiencia renal Mioglobina Músculo Esquelético Rabdomiolisis Necrosis Papilar Renal |
| title_short |
Insuficiencia renal aguda inducida por rabdomiolisis |
| title_full |
Insuficiencia renal aguda inducida por rabdomiolisis |
| title_fullStr |
Insuficiencia renal aguda inducida por rabdomiolisis |
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Insuficiencia renal aguda inducida por rabdomiolisis |
| title_sort |
Insuficiencia renal aguda inducida por rabdomiolisis |
| dc.creator.fl_str_mv |
Nieto Ríos, John Fredy Vega Miranda, Juliana Serna Higuita, Lina María |
| dc.contributor.author.none.fl_str_mv |
Nieto Ríos, John Fredy Vega Miranda, Juliana Serna Higuita, Lina María |
| dc.subject.none.fl_str_mv |
Insuficiencia renal Mioglobina Músculo Esquelético Rabdomiolisis Necrosis Papilar Renal |
| topic |
Insuficiencia renal Mioglobina Músculo Esquelético Rabdomiolisis Necrosis Papilar Renal |
| description |
ABSTRACT: Acute renal failure is a frequent cause of morbidity and mortality in emergency, hospitalization and critical care services. In 15 % of cases it is due to rhabdomyolysis, in which there is breakdown of skeletal muscle with massive necrosis and leakage of muscle cell contents into the circulation. It has many different etiologies. The rhabdomyolysis-induced acute kidney injury results from the combination of several mechanisms, including tubular obstruction, vasoconstriction and oxidative stress. The most important therapeutic measures are: Aggressive repletion of fluids, forced diuresis and avoidance of exposure to nephrotoxic substances. In cases of severe uremia, metabolic acidosis, hiperkalemia or fluid overload it is necessary to start renal replacement therapy. As a rule, kidney function is completely recovered, but these patients have higher risk of future chronic kidney disease. Key words: Acute Renal Failure; Myoglobin; Necrosis; Rhabdomyolysis; Skeletal Muscles. |
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2016 |
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2016 |
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2019-07-30T20:52:41Z |
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2019-07-30T20:52:41Z |
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Nieto-Ríos JF, Vega-Miranda J, Serna-Higuita LM. Insuficiencia renal aguda inducida por rabdomiolisis. Iatreia. 2016 Abr-Jun;29(2):157-169. DOI 10.17533/udea. iatreia.v29n2a05 |
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0121-0793 |
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http://hdl.handle.net/10495/11581 |
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10.17533/udea. iatreia.v29n2a05 |
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2011-7965 |
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Nieto-Ríos JF, Vega-Miranda J, Serna-Higuita LM. Insuficiencia renal aguda inducida por rabdomiolisis. Iatreia. 2016 Abr-Jun;29(2):157-169. DOI 10.17533/udea. iatreia.v29n2a05 0121-0793 10.17533/udea. iatreia.v29n2a05 2011-7965 |
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spa |
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Iatreia |
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Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO) |
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Universidad de Antioquia, Facultad de Medicina |
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Medellín, Colombia |
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Universidad de Antioquia |
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Nieto Ríos, John FredyVega Miranda, JulianaSerna Higuita, Lina María2019-07-30T20:52:41Z2019-07-30T20:52:41Z2016Nieto-Ríos JF, Vega-Miranda J, Serna-Higuita LM. Insuficiencia renal aguda inducida por rabdomiolisis. Iatreia. 2016 Abr-Jun;29(2):157-169. DOI 10.17533/udea. iatreia.v29n2a050121-0793http://hdl.handle.net/10495/1158110.17533/udea. iatreia.v29n2a052011-7965ABSTRACT: Acute renal failure is a frequent cause of morbidity and mortality in emergency, hospitalization and critical care services. In 15 % of cases it is due to rhabdomyolysis, in which there is breakdown of skeletal muscle with massive necrosis and leakage of muscle cell contents into the circulation. It has many different etiologies. The rhabdomyolysis-induced acute kidney injury results from the combination of several mechanisms, including tubular obstruction, vasoconstriction and oxidative stress. The most important therapeutic measures are: Aggressive repletion of fluids, forced diuresis and avoidance of exposure to nephrotoxic substances. In cases of severe uremia, metabolic acidosis, hiperkalemia or fluid overload it is necessary to start renal replacement therapy. As a rule, kidney function is completely recovered, but these patients have higher risk of future chronic kidney disease. Key words: Acute Renal Failure; Myoglobin; Necrosis; Rhabdomyolysis; Skeletal Muscles.RESUMEN: La insuficiencia renal aguda (IRA) es una causa frecuente de morbilidad y mortalidad en los servicios de urgencias, hospitalización y cuidado crítico, siendo la rabdomiolisis responsable del 15 % de los casos en los centros hospitalarios de alta complejidad. La rabdomiolisis consiste en daño muscular con necrosis y liberación a la circulación de componentes intracelulares, y puede tener múltiples causas. El daño renal por rabdomiolisis es multifactorial e incluye obstrucción tubular, vasoconstricción y daño oxidativo. El tratamiento principal de la IRA por rabdomiolisis es la hidratación, forzar la diuresis y evitar los fármacos nefrotóxicos. Cuando el daño es lo suficientemente grave para causar uremia, acidosis metabólica, hiperpotasemia y sobrecarga de volumen se debe recurrir a la terapia de reemplazo renal. Aunque la regla es que se recupere la función renal, estos pacientes tienen mayor riesgo futuro de desarrollar enfermedad renal crónica. Palabras clave: Insuficiencia renal aguda; Mioglobina; Músculo esquelético; Necrosis; Rabdomiolisis12application/pdfspaUniversidad de Antioquia, Facultad de MedicinaMedellín, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/Insuficiencia renalMioglobinaMúsculo EsqueléticoRabdomiolisisNecrosis Papilar RenalInsuficiencia renal aguda inducida por rabdomiolisisIatreiaIatreia157169292ORIGINALInsuficienciarenalaguda_2016_ JohnFredyNietoRíos.pdfInsuficienciarenalaguda_2016_ JohnFredyNietoRíos.pdfapplication/pdf1204672https://bibliotecadigital.udea.edu.co/bitstream/10495/11581/1/Insuficienciarenalaguda_2016_%20JohnFredyNietoR%c3%ados.pdff1ac99e321f255b451b81f8e22457650MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849https://bibliotecadigital.udea.edu.co/bitstream/10495/11581/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80https://bibliotecadigital.udea.edu.co/bitstream/10495/11581/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80https://bibliotecadigital.udea.edu.co/bitstream/10495/11581/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/11581/5/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5510495/11581oai:bibliotecadigital.udea.edu.co:10495/115812021-03-24 21:40:28.572Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.coTk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo= |