Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players
ABSTRACT: Background: Although biochemical markers have been used to monitor training loads (TL), it is unknown if they can be used to predict muscle injuries (MI) in professional football (soccer) players (PFP). Objectives: To evaluate the relationship between the incidence of MI, serum concentrati...
- Autores:
-
Osorio Muñoz, Juan José
Méndez, Edgar
Aguirre Acevedo, Daniel Camilo
Osorio Ciro, Jorge Alberto
Calderón Vélez, Juan Camilo
Gallo Villegas, Jaime Alberto
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/31166
- Acceso en línea:
- https://hdl.handle.net/10495/31166
- Palabra clave:
- Creatina Quinasa
Creatine Kinase
Urea
Traumatismos en Atletas
Athletic Injuries
Fútbol
Soccer
Biomarcadores
Biomarkers
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc/2.5/co/
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UDEA2 |
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Repositorio UdeA |
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|
dc.title.spa.fl_str_mv |
Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players |
title |
Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players |
spellingShingle |
Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players Creatina Quinasa Creatine Kinase Urea Traumatismos en Atletas Athletic Injuries Fútbol Soccer Biomarcadores Biomarkers |
title_short |
Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players |
title_full |
Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players |
title_fullStr |
Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players |
title_full_unstemmed |
Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players |
title_sort |
Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players |
dc.creator.fl_str_mv |
Osorio Muñoz, Juan José Méndez, Edgar Aguirre Acevedo, Daniel Camilo Osorio Ciro, Jorge Alberto Calderón Vélez, Juan Camilo Gallo Villegas, Jaime Alberto |
dc.contributor.author.none.fl_str_mv |
Osorio Muñoz, Juan José Méndez, Edgar Aguirre Acevedo, Daniel Camilo Osorio Ciro, Jorge Alberto Calderón Vélez, Juan Camilo Gallo Villegas, Jaime Alberto |
dc.subject.decs.none.fl_str_mv |
Creatina Quinasa Creatine Kinase Urea Traumatismos en Atletas Athletic Injuries Fútbol Soccer Biomarcadores Biomarkers |
topic |
Creatina Quinasa Creatine Kinase Urea Traumatismos en Atletas Athletic Injuries Fútbol Soccer Biomarcadores Biomarkers |
description |
ABSTRACT: Background: Although biochemical markers have been used to monitor training loads (TL), it is unknown if they can be used to predict muscle injuries (MI) in professional football (soccer) players (PFP). Objectives: To evaluate the relationship between the incidence of MI, serum concentration of creatine phosphokinase (CPK) and urea, as well as TL in PFP. Methods: Twenty-three PFP from a Colombian first-division team were enrolled in a retrospective cohort study. CPK, urea, TL and new MI were measured during 19 weeks. CPK and urea serum levels within 4 weeks before a diagnosed MI were compared to those measured preseason. CPK and urea relationship with TL were analyzed using a mixed-effects model. Results: The subjects had an age of 25.3±4.2 years. Nine subjects presented with MI during follow-up, 66.6% of which were localized to hamstrings. Serum CPK and urea profiles were constructed for each player along the season. Injured players had a significant elevation of these markers within 4 weeks before the injury was clinically evident when compared to their own preseason values. Expected individual increases in CPK and urea according to TL during the season were estimated. Conclusions: Since CPK and urea values rose several weeks before the MI became overt, constructing CPK and urea profiles for each player during the whole preseason and season may help identify peaks in their concentration as arly markers of MI. A tight biochemical control of training may become a preventive strategy for MI, but the use of published reference values is discouraged. |
publishDate |
2018 |
dc.date.issued.none.fl_str_mv |
2018 |
dc.date.accessioned.none.fl_str_mv |
2022-10-09T13:09:04Z |
dc.date.available.none.fl_str_mv |
2022-10-09T13:09:04Z |
dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.hasversion.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
dc.type.local.spa.fl_str_mv |
Artículo de investigación |
format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
status_str |
publishedVersion |
dc.identifier.citation.spa.fl_str_mv |
J Osorio J, A Méndez E, Aguirre-Acevedo D , Osorio-Ciro J, C Calderón J, et al. Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players. Asian J Sports Med. 2018;9(4):e60386. doi: 10.5812/asjsm.60386. |
dc.identifier.issn.none.fl_str_mv |
2008-000X |
dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/10495/31166 |
dc.identifier.doi.none.fl_str_mv |
10.5812/asjsm.60386 |
dc.identifier.eissn.none.fl_str_mv |
2008-7209 |
identifier_str_mv |
J Osorio J, A Méndez E, Aguirre-Acevedo D , Osorio-Ciro J, C Calderón J, et al. Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players. Asian J Sports Med. 2018;9(4):e60386. doi: 10.5812/asjsm.60386. 2008-000X 10.5812/asjsm.60386 2008-7209 |
url |
https://hdl.handle.net/10495/31166 |
dc.language.iso.spa.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Asian J. Sports Med. |
dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc/2.5/co/ |
dc.rights.accessrights.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
dc.rights.creativecommons.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc/4.0/ |
dc.format.extent.spa.fl_str_mv |
10 |
dc.format.mimetype.spa.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Tehran University of Medical Sciences Press |
dc.publisher.group.spa.fl_str_mv |
Grupo Académico de Epidemiología Clínica Grupo de Investigación en Fisiología y Bioquímica - Physis Grupo de Investigación en Medicina Aplicada a la Actividad Física y el Deporte (GRINMADE) |
dc.publisher.place.spa.fl_str_mv |
Teherán, Irán |
institution |
Universidad de Antioquia |
bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstream/10495/31166/1/OsorioJuan_2018_CreatinePhosphokinaseUrea.pdf https://bibliotecadigital.udea.edu.co/bitstream/10495/31166/2/license_rdf https://bibliotecadigital.udea.edu.co/bitstream/10495/31166/3/license.txt |
bitstream.checksum.fl_str_mv |
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bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositorio Institucional Universidad de Antioquia |
repository.mail.fl_str_mv |
andres.perez@udea.edu.co |
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1812173306654097408 |
spelling |
Osorio Muñoz, Juan JoséMéndez, EdgarAguirre Acevedo, Daniel CamiloOsorio Ciro, Jorge AlbertoCalderón Vélez, Juan CamiloGallo Villegas, Jaime Alberto2022-10-09T13:09:04Z2022-10-09T13:09:04Z2018J Osorio J, A Méndez E, Aguirre-Acevedo D , Osorio-Ciro J, C Calderón J, et al. Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football Players. Asian J Sports Med. 2018;9(4):e60386. doi: 10.5812/asjsm.60386.2008-000Xhttps://hdl.handle.net/10495/3116610.5812/asjsm.603862008-7209ABSTRACT: Background: Although biochemical markers have been used to monitor training loads (TL), it is unknown if they can be used to predict muscle injuries (MI) in professional football (soccer) players (PFP). Objectives: To evaluate the relationship between the incidence of MI, serum concentration of creatine phosphokinase (CPK) and urea, as well as TL in PFP. Methods: Twenty-three PFP from a Colombian first-division team were enrolled in a retrospective cohort study. CPK, urea, TL and new MI were measured during 19 weeks. CPK and urea serum levels within 4 weeks before a diagnosed MI were compared to those measured preseason. CPK and urea relationship with TL were analyzed using a mixed-effects model. Results: The subjects had an age of 25.3±4.2 years. Nine subjects presented with MI during follow-up, 66.6% of which were localized to hamstrings. Serum CPK and urea profiles were constructed for each player along the season. Injured players had a significant elevation of these markers within 4 weeks before the injury was clinically evident when compared to their own preseason values. Expected individual increases in CPK and urea according to TL during the season were estimated. Conclusions: Since CPK and urea values rose several weeks before the MI became overt, constructing CPK and urea profiles for each player during the whole preseason and season may help identify peaks in their concentration as arly markers of MI. A tight biochemical control of training may become a preventive strategy for MI, but the use of published reference values is discouraged.COL0007328COL0070223COL000712110application/pdfengTehran University of Medical Sciences PressGrupo Académico de Epidemiología ClínicaGrupo de Investigación en Fisiología y Bioquímica - PhysisGrupo de Investigación en Medicina Aplicada a la Actividad Física y el Deporte (GRINMADE)Teherán, Iráninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc/4.0/Creatine Phosphokinase and Urea as Biochemical Markers of Muscle Injuries in Professional Football PlayersCreatina QuinasaCreatine KinaseUreaTraumatismos en AtletasAthletic InjuriesFútbolSoccerBiomarcadoresBiomarkersAsian J. Sports Med.Asian Journal of Sports Medicine1109ORIGINALOsorioJuan_2018_CreatinePhosphokinaseUrea.pdfOsorioJuan_2018_CreatinePhosphokinaseUrea.pdfArtículo de investigaciónapplication/pdf391747https://bibliotecadigital.udea.edu.co/bitstream/10495/31166/1/OsorioJuan_2018_CreatinePhosphokinaseUrea.pdf8072ada640d606debb0f16fb85373681MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8933https://bibliotecadigital.udea.edu.co/bitstream/10495/31166/2/license_rdfc0c92b0ffc8b7d22d9cf56754a416a76MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/31166/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/31166oai:bibliotecadigital.udea.edu.co:10495/311662022-10-09 08:09:05.188Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |