Leishmanicidal Activity of Passifloricin A and Derivatives
ABSTRACT: Several natural and hemisyntetic passifloricins were assayed against Leishmania panamensis amastigotes. High leishmanicidal activity as well as toxicity was observed. The structure of a new compound is also reported.
- Autores:
-
Cardona Galeano, Wilson
Quiñones Fletcher, Winston
Echeverri López, Luis Fernando
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2004
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/23679
- Acceso en línea:
- http://hdl.handle.net/10495/23679
- Palabra clave:
- Lactonas
Lactones
Passifloricins
Antiparasites
Leishmanicidal activity
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by/2.5/co/
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| dc.title.spa.fl_str_mv |
Leishmanicidal Activity of Passifloricin A and Derivatives |
| title |
Leishmanicidal Activity of Passifloricin A and Derivatives |
| spellingShingle |
Leishmanicidal Activity of Passifloricin A and Derivatives Lactonas Lactones Passifloricins Antiparasites Leishmanicidal activity |
| title_short |
Leishmanicidal Activity of Passifloricin A and Derivatives |
| title_full |
Leishmanicidal Activity of Passifloricin A and Derivatives |
| title_fullStr |
Leishmanicidal Activity of Passifloricin A and Derivatives |
| title_full_unstemmed |
Leishmanicidal Activity of Passifloricin A and Derivatives |
| title_sort |
Leishmanicidal Activity of Passifloricin A and Derivatives |
| dc.creator.fl_str_mv |
Cardona Galeano, Wilson Quiñones Fletcher, Winston Echeverri López, Luis Fernando |
| dc.contributor.author.none.fl_str_mv |
Cardona Galeano, Wilson Quiñones Fletcher, Winston Echeverri López, Luis Fernando |
| dc.subject.decs.none.fl_str_mv |
Lactonas Lactones |
| topic |
Lactonas Lactones Passifloricins Antiparasites Leishmanicidal activity |
| dc.subject.proposal.spa.fl_str_mv |
Passifloricins Antiparasites Leishmanicidal activity |
| description |
ABSTRACT: Several natural and hemisyntetic passifloricins were assayed against Leishmania panamensis amastigotes. High leishmanicidal activity as well as toxicity was observed. The structure of a new compound is also reported. |
| publishDate |
2004 |
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2004 |
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2021-11-01T22:08:54Z |
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2021-11-01T22:08:54Z |
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Cardona, W., Quiñones, W., & Echeverri, L. (2004). Leishmanicidal Activity of Passifloricin A and Derivatives. Molecules, 9(8), 666–672. MDPI AG. Retrieved from http://dx.doi.org/10.3390/90800666 |
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http://hdl.handle.net/10495/23679 |
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10.3390/90800666 |
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1420-3049 |
| identifier_str_mv |
Cardona, W., Quiñones, W., & Echeverri, L. (2004). Leishmanicidal Activity of Passifloricin A and Derivatives. Molecules, 9(8), 666–672. MDPI AG. Retrieved from http://dx.doi.org/10.3390/90800666 10.3390/90800666 1420-3049 |
| url |
http://hdl.handle.net/10495/23679 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Molecules |
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info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by/2.5/co/ |
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openAccess |
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http://creativecommons.org/licenses/by/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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MDPI |
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Química de Plantas Colombianas Química Orgánica de Productos Naturales |
| dc.publisher.place.spa.fl_str_mv |
Basilea, Suiza |
| institution |
Universidad de Antioquia |
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Cardona Galeano, WilsonQuiñones Fletcher, WinstonEcheverri López, Luis Fernando2021-11-01T22:08:54Z2021-11-01T22:08:54Z2004Cardona, W., Quiñones, W., & Echeverri, L. (2004). Leishmanicidal Activity of Passifloricin A and Derivatives. Molecules, 9(8), 666–672. MDPI AG. Retrieved from http://dx.doi.org/10.3390/90800666http://hdl.handle.net/10495/2367910.3390/908006661420-3049ABSTRACT: Several natural and hemisyntetic passifloricins were assayed against Leishmania panamensis amastigotes. High leishmanicidal activity as well as toxicity was observed. The structure of a new compound is also reported.COL0015339COL00153297application/pdfengMDPIQuímica de Plantas ColombianasQuímica Orgánica de Productos NaturalesBasilea, Suizainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Leishmanicidal Activity of Passifloricin A and DerivativesLactonasLactonesPassifloricinsAntiparasitesLeishmanicidal activityMoleculesMolecules66667298ORIGINALCardonaWilson_2004_LeishmanicidalActivityPassifloricin.pdfCardonaWilson_2004_LeishmanicidalActivityPassifloricin.pdfArtículo de investigaciónapplication/pdf158273http://bibliotecadigital.udea.edu.co/bitstream/10495/23679/1/CardonaWilson_2004_LeishmanicidalActivityPassifloricin.pdf81a8e96558defbdf3babf75b16c6a6dcMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927http://bibliotecadigital.udea.edu.co/bitstream/10495/23679/2/license_rdf1646d1f6b96dbbbc38035efc9239ac9cMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/23679/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/23679oai:bibliotecadigital.udea.edu.co:10495/236792021-11-01 17:08:55.099Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |