Presencia de poblaciones leucocitarias en el útero de los rumiantes y sus posibles implicaciones en la reproducción bovina. Revisión de literatura

ABSTRACT: Under physiological conditions the mammal uterus is exposed to fetal and paternal antigens that could generate immune responses harmless toward the semiallogenic conceptus at any time during pregnancy. Several strategies evolved have evolved depending on the specie in order to maintain the...

Full description

Autores:
López Rojas, Luis Ernesto
Maldonado Estrada, Juan Guillermo
Tipo de recurso:
Review article
Fecha de publicación:
1999
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
spa
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/6830
Acceso en línea:
http://hdl.handle.net/10495/6830
Palabra clave:
Bovinos
Placentación epiteliocorial
Bovine
Epitheliochorial placentation
Inmunología veterinaria
Reproducción animal
Rights
openAccess
License
Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
Description
Summary:ABSTRACT: Under physiological conditions the mammal uterus is exposed to fetal and paternal antigens that could generate immune responses harmless toward the semiallogenic conceptus at any time during pregnancy. Several strategies evolved have evolved depending on the specie in order to maintain the fetus alive which includes: type of placentation, the presence of specific cell population at the materno-fetal interface, and specific cytokines produced at the local microenvironment during the pregnancy. The placentation in ruminants is characterized by the presence of some lineage of γδTCR lymphocytes which display specific protective functions similar to that excerpted by NK cell (LGL and GMG) in primates and rodents, respectively. These cells also have similar morphology to NK lineages, but exhibits different expression of specific cell surface markers. The proposal of the present article is to review leukocyte populations present at the ruminant uterus during the processes of implantation, placentation, pregnancy maintenance, and parturition. Thereafter, we focused on the cell surface markers until now characterized and the homologies between ruminants and human or murine uterine leukocyte populations. Finally we shall mention specific topics for development of research in bovine reproductive immunology with potential use for improving reproductive efficiency.