Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells

ABSTRACT: Calcium is the only dietary factor that affects both non-heme and heme iron absorption in humans. Mechanisms behind this effect are not elucidated. An hypothesis is that calcium may modify gene expression of proteins involved in iron absorption. An interesting experimental model for evalua...

Full description

Autores:
Herrera Mejía, Julián
Zapata Builes, Wildeman
Gaitán Charry, Diego Alejandro
Tipo de recurso:
Article of investigation
Fecha de publicación:
2016
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/21387
Acceso en línea:
http://hdl.handle.net/10495/21387
Palabra clave:
Hierro
Iron
Expresión Génica
Gene Expression
Calcio
Calcium
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc/2.5/co/
id UDEA2_c36637002eafeb85303a4422436b1c9d
oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/21387
network_acronym_str UDEA2
network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
title Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
spellingShingle Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
Hierro
Iron
Expresión Génica
Gene Expression
Calcio
Calcium
title_short Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
title_full Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
title_fullStr Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
title_full_unstemmed Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
title_sort Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
dc.creator.fl_str_mv Herrera Mejía, Julián
Zapata Builes, Wildeman
Gaitán Charry, Diego Alejandro
dc.contributor.author.none.fl_str_mv Herrera Mejía, Julián
Zapata Builes, Wildeman
Gaitán Charry, Diego Alejandro
dc.subject.decs.none.fl_str_mv Hierro
Iron
Expresión Génica
Gene Expression
topic Hierro
Iron
Expresión Génica
Gene Expression
Calcio
Calcium
dc.subject.lemb.none.fl_str_mv Calcio
Calcium
description ABSTRACT: Calcium is the only dietary factor that affects both non-heme and heme iron absorption in humans. Mechanisms behind this effect are not elucidated. An hypothesis is that calcium may modify gene expression of proteins involved in iron absorption. An interesting experimental model for evaluating this effect is the human cell line Caco-2, which is easy to use and produces results that strongly correlate with the absorption of iron in humans.
publishDate 2016
dc.date.issued.none.fl_str_mv 2016
dc.date.accessioned.none.fl_str_mv 2021-08-01T17:50:36Z
dc.date.available.none.fl_str_mv 2021-08-01T17:50:36Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
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dc.type.hasversion.spa.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.redcol.spa.fl_str_mv https://purl.org/redcol/resource_type/ART
dc.type.local.spa.fl_str_mv Artículo de investigación
format http://purl.org/coar/resource_type/c_2df8fbb1
status_str publishedVersion
dc.identifier.issn.none.fl_str_mv 0892-6638
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/21387
dc.identifier.doi.none.fl_str_mv 10.1096/fasebj.30.1_supplement.1173.1
dc.identifier.eissn.none.fl_str_mv 1530-6860
identifier_str_mv 0892-6638
10.1096/fasebj.30.1_supplement.1173.1
1530-6860
url http://hdl.handle.net/10495/21387
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv FASEB J
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.uri.*.fl_str_mv https://creativecommons.org/licenses/by-nc/2.5/co/
dc.rights.accessrights.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.creativecommons.spa.fl_str_mv https://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc/2.5/co/
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dc.format.extent.spa.fl_str_mv 2
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Federation of American Society of Experimental Biology (FASEB)
dc.publisher.group.spa.fl_str_mv Alimentación y Nutrición Humana
dc.publisher.place.spa.fl_str_mv Bethesda, Estados Unidos
institution Universidad de Antioquia
bitstream.url.fl_str_mv http://bibliotecadigital.udea.edu.co/bitstream/10495/21387/1/HerreraJulian_2016_CalciumEffectGene.pdf
http://bibliotecadigital.udea.edu.co/bitstream/10495/21387/2/license.txt
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repository.name.fl_str_mv Repositorio Institucional Universidad de Antioquia
repository.mail.fl_str_mv andres.perez@udea.edu.co
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spelling Herrera Mejía, JuliánZapata Builes, WildemanGaitán Charry, Diego Alejandro2021-08-01T17:50:36Z2021-08-01T17:50:36Z20160892-6638http://hdl.handle.net/10495/2138710.1096/fasebj.30.1_supplement.1173.11530-6860ABSTRACT: Calcium is the only dietary factor that affects both non-heme and heme iron absorption in humans. Mechanisms behind this effect are not elucidated. An hypothesis is that calcium may modify gene expression of proteins involved in iron absorption. An interesting experimental model for evaluating this effect is the human cell line Caco-2, which is easy to use and produces results that strongly correlate with the absorption of iron in humans.COL00004072application/pdfengFederation of American Society of Experimental Biology (FASEB)Alimentación y Nutrición HumanaBethesda, Estados Unidosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc/4.0/Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cellsHierroIronExpresión GénicaGene ExpressionCalcioCalciumFASEB JFASEB Journal1230Suplemento 1ORIGINALHerreraJulian_2016_CalciumEffectGene.pdfHerreraJulian_2016_CalciumEffectGene.pdfArtículo de investigaciónapplication/pdf77559http://bibliotecadigital.udea.edu.co/bitstream/10495/21387/1/HerreraJulian_2016_CalciumEffectGene.pdf48a205252c74f7b99ffe8dd585c08fafMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/21387/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5210495/21387oai:bibliotecadigital.udea.edu.co:10495/213872021-10-25 13:39:45.99Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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