Calcium effect on gene expression of proteins involved on iron absorption by Caco 2 cells
ABSTRACT: Calcium is the only dietary factor that affects both non-heme and heme iron absorption in humans. Mechanisms behind this effect are not elucidated. An hypothesis is that calcium may modify gene expression of proteins involved in iron absorption. An interesting experimental model for evalua...
- Autores:
-
Herrera Mejía, Julián
Zapata Builes, Wildeman
Gaitán Charry, Diego Alejandro
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/21387
- Acceso en línea:
- http://hdl.handle.net/10495/21387
- Palabra clave:
- Hierro
Iron
Expresión Génica
Gene Expression
Calcio
Calcium
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by-nc/2.5/co/
| Summary: | ABSTRACT: Calcium is the only dietary factor that affects both non-heme and heme iron absorption in humans. Mechanisms behind this effect are not elucidated. An hypothesis is that calcium may modify gene expression of proteins involved in iron absorption. An interesting experimental model for evaluating this effect is the human cell line Caco-2, which is easy to use and produces results that strongly correlate with the absorption of iron in humans. |
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