Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability
ABSTRACT: Red-tail coral snake (Micrurus mipartitus) is a long and thin bicolor coral snake widely distributed in Colombia and is the coral that causes the majority of accidents in the Andean region, so it is important to keep this species in captivity for anti-venom production and research. However...
- Autores:
-
Henao Duque, Ana María
Núñez Rangel, Vitelbina
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/20258
- Acceso en línea:
- http://hdl.handle.net/10495/20258
- Palabra clave:
- Serpientes
Serpentes
Víbora
Vipers
Alimentación forzada
Forced feeding
Mortalidad
Mortality
Antivenom
Coral rabo de ají : Micrurus mipartitus
Antiveneno
http://aims.fao.org/aos/agrovoc/c_14209
http://aims.fao.org/aos/agrovoc/c_15208
http://aims.fao.org/aos/agrovoc/c_3038
http://aims.fao.org/aos/agrovoc/c_4945
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-sa/2.5/co/
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| dc.title.spa.fl_str_mv |
Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability |
| dc.title.alternative.spa.fl_str_mv |
Mantenimiento en cautiverio de la coral rabo de ají (Micrurus mipartitus) y evaluación en la variabilidad individual de su veneno |
| title |
Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability |
| spellingShingle |
Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability Serpientes Serpentes Víbora Vipers Alimentación forzada Forced feeding Mortalidad Mortality Antivenom Coral rabo de ají : Micrurus mipartitus Antiveneno http://aims.fao.org/aos/agrovoc/c_14209 http://aims.fao.org/aos/agrovoc/c_15208 http://aims.fao.org/aos/agrovoc/c_3038 http://aims.fao.org/aos/agrovoc/c_4945 |
| title_short |
Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability |
| title_full |
Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability |
| title_fullStr |
Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability |
| title_full_unstemmed |
Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability |
| title_sort |
Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variability |
| dc.creator.fl_str_mv |
Henao Duque, Ana María Núñez Rangel, Vitelbina |
| dc.contributor.author.none.fl_str_mv |
Henao Duque, Ana María Núñez Rangel, Vitelbina |
| dc.subject.agrovoc.none.fl_str_mv |
Serpientes Serpentes Víbora Vipers Alimentación forzada Forced feeding Mortalidad Mortality |
| topic |
Serpientes Serpentes Víbora Vipers Alimentación forzada Forced feeding Mortalidad Mortality Antivenom Coral rabo de ají : Micrurus mipartitus Antiveneno http://aims.fao.org/aos/agrovoc/c_14209 http://aims.fao.org/aos/agrovoc/c_15208 http://aims.fao.org/aos/agrovoc/c_3038 http://aims.fao.org/aos/agrovoc/c_4945 |
| dc.subject.proposal.spa.fl_str_mv |
Antivenom Coral rabo de ají : Micrurus mipartitus Antiveneno |
| dc.subject.agrovocuri.none.fl_str_mv |
http://aims.fao.org/aos/agrovoc/c_14209 http://aims.fao.org/aos/agrovoc/c_15208 http://aims.fao.org/aos/agrovoc/c_3038 http://aims.fao.org/aos/agrovoc/c_4945 |
| description |
ABSTRACT: Red-tail coral snake (Micrurus mipartitus) is a long and thin bicolor coral snake widely distributed in Colombia and is the coral that causes the majority of accidents in the Andean region, so it is important to keep this species in captivity for anti-venom production and research. However, maintaining this species in captivity is very difficult because it refuses to feed, in addition to the high mortality rate due to maladaptation syndrome. In this study a force feeding diet, diverse substrates for maintenance and a milking technique were evaluated. Additionally, individual variability of the venom was determined by High Performance Liquid Chromatography (HPLC), Sodium Dodecyl Sulfate- Polyacrylamide Gel Electrophoresis (SDS-PAGE) and Coagulant, Anticoagulant and Hemolytic activities. The results of this study demonstrate that it was possible to increase the survival rate of this species in captivity and to determine some of the important factors in the maintenance. As to the individual variability of the venom, we found differences in number and intensity of peaks recovered by chromatography and also displayed variations in some of its biological activities. |
| publishDate |
2016 |
| dc.date.issued.none.fl_str_mv |
2016 |
| dc.date.accessioned.none.fl_str_mv |
2021-06-23T01:24:22Z |
| dc.date.available.none.fl_str_mv |
2021-06-23T01:24:22Z |
| dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
| dc.type.local.spa.fl_str_mv |
Artículo de investigación |
| format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| status_str |
publishedVersion |
| dc.identifier.issn.none.fl_str_mv |
0120-548X |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/20258 |
| dc.identifier.doi.none.fl_str_mv |
10.15446/abc.v21n3.51651 |
| dc.identifier.eissn.none.fl_str_mv |
1900-1649 |
| identifier_str_mv |
0120-548X 10.15446/abc.v21n3.51651 1900-1649 |
| url |
http://hdl.handle.net/10495/20258 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Acta Biolo Colomb |
| dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by-nc-sa/2.5/co/ |
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http://purl.org/coar/access_right/c_abf2 |
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https://creativecommons.org/licenses/by-nc-sa/4.0/ |
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openAccess |
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http://creativecommons.org/licenses/by-nc-sa/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-sa/4.0/ |
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8 |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
Universidad Nacional de Colombia, Facultad de Ciencias, Departamento de Biología |
| dc.publisher.group.spa.fl_str_mv |
Toxinología Alternativas Terapéuticas y Alimentarias |
| dc.publisher.place.spa.fl_str_mv |
Bogotá, Colombia |
| institution |
Universidad de Antioquia |
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andres.perez@udea.edu.co |
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1812173174663544832 |
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Henao Duque, Ana MaríaNúñez Rangel, Vitelbina2021-06-23T01:24:22Z2021-06-23T01:24:22Z20160120-548Xhttp://hdl.handle.net/10495/2025810.15446/abc.v21n3.516511900-1649ABSTRACT: Red-tail coral snake (Micrurus mipartitus) is a long and thin bicolor coral snake widely distributed in Colombia and is the coral that causes the majority of accidents in the Andean region, so it is important to keep this species in captivity for anti-venom production and research. However, maintaining this species in captivity is very difficult because it refuses to feed, in addition to the high mortality rate due to maladaptation syndrome. In this study a force feeding diet, diverse substrates for maintenance and a milking technique were evaluated. Additionally, individual variability of the venom was determined by High Performance Liquid Chromatography (HPLC), Sodium Dodecyl Sulfate- Polyacrylamide Gel Electrophoresis (SDS-PAGE) and Coagulant, Anticoagulant and Hemolytic activities. The results of this study demonstrate that it was possible to increase the survival rate of this species in captivity and to determine some of the important factors in the maintenance. As to the individual variability of the venom, we found differences in number and intensity of peaks recovered by chromatography and also displayed variations in some of its biological activities.RESUMEN: La coral “rabo de ají” es una coral bicolor larga y delgada. Esta especie está ampliamente distribuida en Colombia y es la coral que causa el mayor número de accidentes en la región Andina, por esto es importante mantener esta especie en cautiverio con fines de producción de antivenenos e investigación. No obstante, el mantenimiento de esta especie en cautiverio es difícil, debido a que se rehúsan a alimentarse voluntariamente y a que presentan alta mortalidad por el denominado síndrome de mal adaptación. En este estudio se evaluaron varios sustratos para el mantenimiento, además de una dieta forzada y una técnica de ordeño. Adicionalmente, se evaluó la variabilidad individual del veneno a través de cromatografía liquida de alta eficiencia (HPLC), electroforesis (SDS-PAGE) y las actividades coagulante, anticoagulante y hemolítica indirecta. Los resultados de este estudio demostraron que fue posible incrementar la sobrevivencia de esta especie en cautiverio, así como determinar algunos factores importantes en su mantenimiento. A partir de la evaluación del veneno se encontraron diferencias en el número y en la intensidad de picos en la cromatografía, así como en algunas de sus actividades biológicas.COL00144768application/pdfengUniversidad Nacional de Colombia, Facultad de Ciencias, Departamento de BiologíaToxinología Alternativas Terapéuticas y AlimentariasBogotá, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/Maintenance of red-tail coral snake (Micrurus mipartitus) in captivity and evaluation of individual venom variabilityMantenimiento en cautiverio de la coral rabo de ají (Micrurus mipartitus) y evaluación en la variabilidad individual de su venenoSerpientesSerpentesVíboraVipersAlimentación forzadaForced feedingMortalidadMortalityAntivenomCoral rabo de ají : Micrurus mipartitusAntivenenohttp://aims.fao.org/aos/agrovoc/c_14209http://aims.fao.org/aos/agrovoc/c_15208http://aims.fao.org/aos/agrovoc/c_3038http://aims.fao.org/aos/agrovoc/c_4945Acta Biolo ColombActa Biológica Colombiana593600213CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81051http://bibliotecadigital.udea.edu.co/bitstream/10495/20258/2/license_rdfe2060682c9c70d4d30c83c51448f4eedMD52ORIGINALHenaoAna_2016_MaintenanceCoralSnake.pdfHenaoAna_2016_MaintenanceCoralSnake.pdfArtículo de investigaciónapplication/pdf318533http://bibliotecadigital.udea.edu.co/bitstream/10495/20258/1/HenaoAna_2016_MaintenanceCoralSnake.pdfb79a9d9fb71693890c5020805391a1adMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/20258/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/20258oai:bibliotecadigital.udea.edu.co:10495/202582021-06-22 20:24:22.62Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |