Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
ABSTRACT: Several perinaphthenone/phenylphenalenone compounds were synthesized to establish a relationship between structure and antifungal activity against Mycosphaerella fijiensis. Substitutions on the unsaturated carbonyl system or addition of a phenyl group reduced antibiotic activity.
- Autores:
-
Quiñones Fletcher, Winston
Escobar Peláez, Gustavo
Echeverri López, Luis Fernando
Torres, Fernando
Rosero Burbano, Fernando Yoni
Valencia Arango, Víctor Hugo
Cardona Gómez, Gloria Patricia
Gallego Rúa, Adriana María
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2000
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- eng
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/23690
- Acceso en línea:
- http://hdl.handle.net/10495/23690
- Palabra clave:
- Fenalenos
Phenalenes
Antifúngicos
Antifungal Agents
Síntesis
Synthesis
Mycosphaerella fijiensis
http://aims.fao.org/aos/agrovoc/c_3def4163
http://aims.fao.org/aos/agrovoc/c_27259
https://id.nlm.nih.gov/mesh/D043803
https://id.nlm.nih.gov/mesh/D000935
- Rights
- openAccess
- License
- https://creativecommons.org/licenses/by/4.0/
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| dc.title.spa.fl_str_mv |
Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs |
| title |
Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs |
| spellingShingle |
Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs Fenalenos Phenalenes Antifúngicos Antifungal Agents Síntesis Synthesis Mycosphaerella fijiensis http://aims.fao.org/aos/agrovoc/c_3def4163 http://aims.fao.org/aos/agrovoc/c_27259 https://id.nlm.nih.gov/mesh/D043803 https://id.nlm.nih.gov/mesh/D000935 |
| title_short |
Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs |
| title_full |
Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs |
| title_fullStr |
Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs |
| title_full_unstemmed |
Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs |
| title_sort |
Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs |
| dc.creator.fl_str_mv |
Quiñones Fletcher, Winston Escobar Peláez, Gustavo Echeverri López, Luis Fernando Torres, Fernando Rosero Burbano, Fernando Yoni Valencia Arango, Víctor Hugo Cardona Gómez, Gloria Patricia Gallego Rúa, Adriana María |
| dc.contributor.author.none.fl_str_mv |
Quiñones Fletcher, Winston Escobar Peláez, Gustavo Echeverri López, Luis Fernando Torres, Fernando Rosero Burbano, Fernando Yoni Valencia Arango, Víctor Hugo Cardona Gómez, Gloria Patricia Gallego Rúa, Adriana María |
| dc.contributor.researchgroup.spa.fl_str_mv |
Química Orgánica de Productos Naturales |
| dc.subject.decs.none.fl_str_mv |
Fenalenos Phenalenes Antifúngicos Antifungal Agents |
| topic |
Fenalenos Phenalenes Antifúngicos Antifungal Agents Síntesis Synthesis Mycosphaerella fijiensis http://aims.fao.org/aos/agrovoc/c_3def4163 http://aims.fao.org/aos/agrovoc/c_27259 https://id.nlm.nih.gov/mesh/D043803 https://id.nlm.nih.gov/mesh/D000935 |
| dc.subject.agrovoc.none.fl_str_mv |
Síntesis Synthesis Mycosphaerella fijiensis |
| dc.subject.agrovocuri.none.fl_str_mv |
http://aims.fao.org/aos/agrovoc/c_3def4163 http://aims.fao.org/aos/agrovoc/c_27259 |
| dc.subject.meshuri.none.fl_str_mv |
https://id.nlm.nih.gov/mesh/D043803 https://id.nlm.nih.gov/mesh/D000935 |
| description |
ABSTRACT: Several perinaphthenone/phenylphenalenone compounds were synthesized to establish a relationship between structure and antifungal activity against Mycosphaerella fijiensis. Substitutions on the unsaturated carbonyl system or addition of a phenyl group reduced antibiotic activity. |
| publishDate |
2000 |
| dc.date.issued.none.fl_str_mv |
2000 |
| dc.date.accessioned.none.fl_str_mv |
2021-11-02T15:04:29Z |
| dc.date.available.none.fl_str_mv |
2021-11-02T15:04:29Z |
| dc.type.spa.fl_str_mv |
Artículo de investigación |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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https://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/article |
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Quiñones, W., Escobar, G., Echeverri, F., Torres, F., Rosero, Y., Arango, V., Cardona, G., et al. (2000). Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs. Molecules, 5(12), 974–980. Retrieved from http://dx.doi.org/10.3390/50700974 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/23690 |
| dc.identifier.doi.none.fl_str_mv |
10.3390/50700974 |
| dc.identifier.eissn.none.fl_str_mv |
1420-3049 |
| identifier_str_mv |
Quiñones, W., Escobar, G., Echeverri, F., Torres, F., Rosero, Y., Arango, V., Cardona, G., et al. (2000). Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs. Molecules, 5(12), 974–980. Retrieved from http://dx.doi.org/10.3390/50700974 10.3390/50700974 1420-3049 |
| url |
http://hdl.handle.net/10495/23690 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Molecules |
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980 |
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7 |
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974 |
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5 |
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Molecules |
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Basilea, Suiza |
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Quiñones Fletcher, WinstonEscobar Peláez, GustavoEcheverri López, Luis FernandoTorres, FernandoRosero Burbano, Fernando YoniValencia Arango, Víctor HugoCardona Gómez, Gloria PatriciaGallego Rúa, Adriana MaríaQuímica Orgánica de Productos Naturales2021-11-02T15:04:29Z2021-11-02T15:04:29Z2000Quiñones, W., Escobar, G., Echeverri, F., Torres, F., Rosero, Y., Arango, V., Cardona, G., et al. (2000). Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs. Molecules, 5(12), 974–980. Retrieved from http://dx.doi.org/10.3390/50700974http://hdl.handle.net/10495/2369010.3390/507009741420-3049ABSTRACT: Several perinaphthenone/phenylphenalenone compounds were synthesized to establish a relationship between structure and antifungal activity against Mycosphaerella fijiensis. Substitutions on the unsaturated carbonyl system or addition of a phenyl group reduced antibiotic activity.COL00153397application/pdfengMDPIBasilea, Suizahttps://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/2.5/co/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Synthesis and Antifungal Activity of Musa Phytoalexins and Structural AnalogsArtículo de investigaciónhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARThttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionFenalenosPhenalenesAntifúngicosAntifungal AgentsSíntesisSynthesisMycosphaerella fijiensishttp://aims.fao.org/aos/agrovoc/c_3def4163http://aims.fao.org/aos/agrovoc/c_27259https://id.nlm.nih.gov/mesh/D043803https://id.nlm.nih.gov/mesh/D000935Molecules98079745MoleculesPublicationORIGINALQuiñonesWinston_2000_SynthesisMusaPhytoalexins.pdfQuiñonesWinston_2000_SynthesisMusaPhytoalexins.pdfArtículo de investigaciónapplication/pdf33907https://bibliotecadigital.udea.edu.co/bitstreams/65018050-2635-4891-84e9-224fb1441e48/download1d463652185cb98320c487a91299b6a1MD51trueAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927https://bibliotecadigital.udea.edu.co/bitstreams/db88c906-813b-4acd-9678-6f2bdab5bb57/download1646d1f6b96dbbbc38035efc9239ac9cMD52falseAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstreams/aab2f7fb-9c69-4108-9f7d-48b9ae1f2a72/download8a4605be74aa9ea9d79846c1fba20a33MD53falseAnonymousREADTEXTQuiñonesWinston_2000_SynthesisMusaPhytoalexins.pdf.txtQuiñonesWinston_2000_SynthesisMusaPhytoalexins.pdf.txtExtracted texttext/plain15832https://bibliotecadigital.udea.edu.co/bitstreams/0bdea435-0b4d-4e04-b287-cea1cf68455b/downloada48e1b3ee0477afa73120de096e5283dMD54falseAnonymousREADTHUMBNAILQuiñonesWinston_2000_SynthesisMusaPhytoalexins.pdf.jpgQuiñonesWinston_2000_SynthesisMusaPhytoalexins.pdf.jpgGenerated Thumbnailimage/jpeg14955https://bibliotecadigital.udea.edu.co/bitstreams/644ef669-5290-4846-af77-3ba9d63d7110/download0c1a1465a2670e3ac7ff68d1456c7274MD55falseAnonymousREAD10495/23690oai:bibliotecadigital.udea.edu.co:10495/236902025-03-26 21:45:56.299https://creativecommons.org/licenses/by/4.0/open.accesshttps://bibliotecadigital.udea.edu.coRepositorio Institucional de la Universidad de Antioquiaaplicacionbibliotecadigitalbiblioteca@udea.edu.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 |