Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs

ABSTRACT: Several perinaphthenone/phenylphenalenone compounds were synthesized to establish a relationship between structure and antifungal activity against Mycosphaerella fijiensis. Substitutions on the unsaturated carbonyl system or addition of a phenyl group reduced antibiotic activity.

Autores:
Quiñones Fletcher, Winston
Escobar Peláez, Gustavo
Echeverri López, Luis Fernando
Torres, Fernando
Rosero Burbano, Fernando Yoni
Valencia Arango, Víctor Hugo
Cardona Gómez, Gloria Patricia
Gallego Rúa, Adriana María
Tipo de recurso:
Article of investigation
Fecha de publicación:
2000
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
eng
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/23690
Acceso en línea:
http://hdl.handle.net/10495/23690
Palabra clave:
Phenalenes
Fenalenos
/chemical synthesis
/síntesis química
Mycosphaerella fijiensis
Antifungal activity
http://aims.fao.org/aos/agrovoc/c_27259
Rights
openAccess
License
http://creativecommons.org/licenses/by/2.5/co/
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oai_identifier_str oai:bibliotecadigital.udea.edu.co:10495/23690
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network_name_str Repositorio UdeA
repository_id_str
dc.title.spa.fl_str_mv Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
title Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
spellingShingle Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
Phenalenes
Fenalenos
/chemical synthesis
/síntesis química
Mycosphaerella fijiensis
Antifungal activity
http://aims.fao.org/aos/agrovoc/c_27259
title_short Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
title_full Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
title_fullStr Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
title_full_unstemmed Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
title_sort Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs
dc.creator.fl_str_mv Quiñones Fletcher, Winston
Escobar Peláez, Gustavo
Echeverri López, Luis Fernando
Torres, Fernando
Rosero Burbano, Fernando Yoni
Valencia Arango, Víctor Hugo
Cardona Gómez, Gloria Patricia
Gallego Rúa, Adriana María
dc.contributor.author.none.fl_str_mv Quiñones Fletcher, Winston
Escobar Peláez, Gustavo
Echeverri López, Luis Fernando
Torres, Fernando
Rosero Burbano, Fernando Yoni
Valencia Arango, Víctor Hugo
Cardona Gómez, Gloria Patricia
Gallego Rúa, Adriana María
dc.subject.decs.none.fl_str_mv Phenalenes
Fenalenos
/chemical synthesis
/síntesis química
topic Phenalenes
Fenalenos
/chemical synthesis
/síntesis química
Mycosphaerella fijiensis
Antifungal activity
http://aims.fao.org/aos/agrovoc/c_27259
dc.subject.agrovoc.none.fl_str_mv Mycosphaerella fijiensis
dc.subject.proposal.spa.fl_str_mv Antifungal activity
dc.subject.agrovocuri.none.fl_str_mv http://aims.fao.org/aos/agrovoc/c_27259
description ABSTRACT: Several perinaphthenone/phenylphenalenone compounds were synthesized to establish a relationship between structure and antifungal activity against Mycosphaerella fijiensis. Substitutions on the unsaturated carbonyl system or addition of a phenyl group reduced antibiotic activity.
publishDate 2000
dc.date.issued.none.fl_str_mv 2000
dc.date.accessioned.none.fl_str_mv 2021-11-02T15:04:29Z
dc.date.available.none.fl_str_mv 2021-11-02T15:04:29Z
dc.type.spa.fl_str_mv info:eu-repo/semantics/article
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dc.type.local.spa.fl_str_mv Artículo de investigación
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dc.identifier.citation.spa.fl_str_mv Quiñones, W., Escobar, G., Echeverri, F., Torres, F., Rosero, Y., Arango, V., Cardona, G., et al. (2000). Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs. Molecules, 5(12), 974–980. Retrieved from http://dx.doi.org/10.3390/50700974
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10495/23690
dc.identifier.doi.none.fl_str_mv 10.3390/50700974
dc.identifier.eissn.none.fl_str_mv 1420-3049
identifier_str_mv Quiñones, W., Escobar, G., Echeverri, F., Torres, F., Rosero, Y., Arango, V., Cardona, G., et al. (2000). Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs. Molecules, 5(12), 974–980. Retrieved from http://dx.doi.org/10.3390/50700974
10.3390/50700974
1420-3049
url http://hdl.handle.net/10495/23690
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartofjournalabbrev.spa.fl_str_mv Molecules
dc.rights.spa.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/2.5/co/
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.format.extent.spa.fl_str_mv 7
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv MDPI
dc.publisher.group.spa.fl_str_mv Química Orgánica de Productos Naturales
dc.publisher.place.spa.fl_str_mv Basilea, Suiza
institution Universidad de Antioquia
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spelling Quiñones Fletcher, WinstonEscobar Peláez, GustavoEcheverri López, Luis FernandoTorres, FernandoRosero Burbano, Fernando YoniValencia Arango, Víctor HugoCardona Gómez, Gloria PatriciaGallego Rúa, Adriana María2021-11-02T15:04:29Z2021-11-02T15:04:29Z2000Quiñones, W., Escobar, G., Echeverri, F., Torres, F., Rosero, Y., Arango, V., Cardona, G., et al. (2000). Synthesis and Antifungal Activity of Musa Phytoalexins and Structural Analogs. Molecules, 5(12), 974–980. Retrieved from http://dx.doi.org/10.3390/50700974http://hdl.handle.net/10495/2369010.3390/507009741420-3049ABSTRACT: Several perinaphthenone/phenylphenalenone compounds were synthesized to establish a relationship between structure and antifungal activity against Mycosphaerella fijiensis. Substitutions on the unsaturated carbonyl system or addition of a phenyl group reduced antibiotic activity.COL00153397application/pdfengMDPIQuímica Orgánica de Productos NaturalesBasilea, Suizainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by/4.0/Synthesis and Antifungal Activity of Musa Phytoalexins and Structural AnalogsPhenalenesFenalenos/chemical synthesis/síntesis químicaMycosphaerella fijiensisAntifungal activityhttp://aims.fao.org/aos/agrovoc/c_27259MoleculesMolecules97498057ORIGINALQuiñonesWinston_2000_SynthesisMusaPhytoalexins.pdfQuiñonesWinston_2000_SynthesisMusaPhytoalexins.pdfArtículo de investigaciónapplication/pdf33907http://bibliotecadigital.udea.edu.co/bitstream/10495/23690/1/Qui%c3%b1onesWinston_2000_SynthesisMusaPhytoalexins.pdf1d463652185cb98320c487a91299b6a1MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8927http://bibliotecadigital.udea.edu.co/bitstream/10495/23690/2/license_rdf1646d1f6b96dbbbc38035efc9239ac9cMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://bibliotecadigital.udea.edu.co/bitstream/10495/23690/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5310495/23690oai:bibliotecadigital.udea.edu.co:10495/236902021-11-02 10:04:29.771Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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