Gestación prolongada asociada con la prescripción inadecuada de medroxiprogesterona acetato. ¿Es racional y ético el uso de progestágenos exógenos en perras?

ABSTRACT: Medroxiprogesterone acetate (MPA) has been commonly used as a contraceptive in bitches by its effect on preventing estrous presentation, instead of abundant evidence on undesirable collateral effects such as uterine and mammary tumors and nodules, Cystic endometrial hyperplasia-pyometra co...

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Autores:
González Domínguez, María Soledad
Maldonado Estrada, Juan Guillermo
Tipo de recurso:
Article of journal
Fecha de publicación:
2006
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
spa
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/7781
Acceso en línea:
http://hdl.handle.net/10495/7781
Palabra clave:
Caninos
Ciclo estral
Distocia
Maceración fetal
Progestágenos
Reproduccion animal
Rights
openAccess
License
Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
Description
Summary:ABSTRACT: Medroxiprogesterone acetate (MPA) has been commonly used as a contraceptive in bitches by its effect on preventing estrous presentation, instead of abundant evidence on undesirable collateral effects such as uterine and mammary tumors and nodules, Cystic endometrial hyperplasia-pyometra complex, as well as acromegaly-like lesions. In this report a 6 year -old Fox-terrier wire coat bitch is presented which was administered a depot MPA formulation in order to prevent an undesired mating-related pregnancy that was attended at the by a prolonged pregnancy at day 74 after the undesired mating. The patient showed distended abdomen, dyspnea, with no changes in hemoleukograms values, but with macerated fetuses as diagnosed by clinical and radiographic findings. An elective cesarean operation followed by ovary hysterectomy was performed. The patient showed an optimal clinical evolution. Several aspects related to the use of MPA in canine reproduction, the recommendation to cautiously prescribe its use as contraceptive agents in bitches, as well as the consideration of other alternatives for management of undesired mating in dogs, are discussed.