Efecto del consumo de linaza en el perfil lipídico, el control del cáncer y como terapia de reemplazo hormonal en la menopausia : una revisión sistemática de ensayos clínicos aleatorizados

ABSTRACT: To evaluate the effects of flaxseed consumption in changing the lipid profile, cancer control and hormone replacement therapy at menopause and andropause in individuals of all ages. Materials and methods: We conducted a systematic review of randomized controlled trials that examined the ef...

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Autores:
Arango Alzate, Catalina María
Molina Castaño, Carlos Federico
Gaviria Gómez, Berta Lucia
Ruiz Pineda, Adriana Marcela
López Marín, Beatriz Estella
Tipo de recurso:
Review article
Fecha de publicación:
2011
Institución:
Universidad de Antioquia
Repositorio:
Repositorio UdeA
Idioma:
spa
OAI Identifier:
oai:bibliotecadigital.udea.edu.co:10495/11016
Acceso en línea:
http://hdl.handle.net/10495/11016
Palabra clave:
Enfermedades crónicas - Prevención y control
Hiperlipidemias
Linaza
Lípidos
Menopausia
Metanálisis
Neoplasias de la mama - Prevención y control
Terapia de reemplazo hormonal
Rights
openAccess
License
Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
Description
Summary:ABSTRACT: To evaluate the effects of flaxseed consumption in changing the lipid profile, cancer control and hormone replacement therapy at menopause and andropause in individuals of all ages. Materials and methods: We conducted a systematic review of randomized controlled trials that examined the effects of flaxseed consumption on body weight reduction, change in blood lipid levels, cancer control and menopausal symptoms. We used Pub-Med, Lilacs, the libraries of PAHO and WHO, and clinical trials published in Cochrane between January 1, 2000 and June 30, 2010. The articles that met the inclusion criteria were assessed for methodological quality. Results: We included 49 articles. Studies reported that flaxseed consumption generates small changes in blood lipid concentrations, improvement in menopausal symptoms, promotes the reduction of tumor proliferation rates and increased apoptosis in breast and prostate cancer Conclusions: The results are not yet sufficient to recommend the use of flaxseed for the control of hypercholesterolemia in patients with dyslipidemia. The evidence favors flaxseed as an alternative adjuvant therapy for breast and prostate cancer treatment, and reduction of menopause symptoms.