Melanoma maligno de la mucosa oral. Reporte de un caso

ABSTRACT: Oral melanomas are rare tumors corresponding to 0.5% of all the oral malignancies. The hard palate and gingiva are more frequently affected. At the moment of diagnosis they are generally in an advanced stage. We describe a case of a 70 years old male with nodular and pigmented lesion in hard palate and other macular pigmented lesions, besides a 2cm cervical nodule. The histo-pathological study showed an extensive infiltration by moderately pleomorphic spindle and epitheliod tumoral cells with melanin pigment in the cytoplasm. Immune-histo-chemical staining was positive to S-100 and HMB-45. Cytology by aspiration of the cervical node was carried out with a fine needle, showing cells with wide cytoplasm and presence of melanin pigment and pleomorphic nuclei. The differential diagnosis includes benign and malign vascular tumors, tumors and cysts of salivary glands, and benign pigmented lesions of the mucosa.

• Autores: Rendón Henao, Javier; Santa Sáenz, Diana; Jiménez Salazar, Juan David
• Tipo de recurso: Article of journal
• Fecha de publicación: 2007
• Institución: Universidad de Antioquia
• Repositorio: Repositorio UdeA
• Idioma: spa
• OAI Identifier: oai:bibliotecadigital.udea.edu.co:10495/7411
• Acceso en línea: http://hdl.handle.net/10495/7411
• Palabra clave: Melanoma de la cavidad oral; Lesiones pigmentadas de la mucosa oral; Inmunohistoquímica; S-100; Malignant melanoma of the oral cavity; Pigmented lesions of the oral cavity; Immune-histo-chemistry; Melanoma; Boca - Heridas; lesiones, etc; Mucosa oral; Neoplasias de la boca
• Rights: openAccess
• License: Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)