Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada
ABSTRACT: In the following article the effects of two types of hydroxiapatites on bone synthesis and properties were evaluated. One of them (OseoU) was synthesized at two different temperatures to compare it to a commercial mixture of hydroxiapatite (Osteogen®) commonly used in several surgical proc...
- Autores:
-
Jaramillo Gómez, Carlos David
Rivera Posada, Jairo Alonso
O'Byrne, Johan
Congote, Diego
Restrepo Betancur, Luis Fernando
- Tipo de recurso:
- Article of investigation
- Fecha de publicación:
- 2009
- Institución:
- Universidad de Antioquia
- Repositorio:
- Repositorio UdeA
- Idioma:
- spa
- OAI Identifier:
- oai:bibliotecadigital.udea.edu.co:10495/8334
- Acceso en línea:
- http://hdl.handle.net/10495/8334
- Palabra clave:
- Rights
- openAccess
- License
- Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)
| id |
UDEA2_9aafe4fcf9c58b07e1d6f9a1598a901c |
|---|---|
| oai_identifier_str |
oai:bibliotecadigital.udea.edu.co:10495/8334 |
| network_acronym_str |
UDEA2 |
| network_name_str |
Repositorio UdeA |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada |
| dc.title.alternative.spa.fl_str_mv |
Comparation of osteoconduction and osteointegration properties of a commercial reabsorbable hydroxypatitie with respect to a synthetyzed one |
| title |
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada |
| spellingShingle |
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada |
| title_short |
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada |
| title_full |
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada |
| title_fullStr |
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada |
| title_full_unstemmed |
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada |
| title_sort |
Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizada |
| dc.creator.fl_str_mv |
Jaramillo Gómez, Carlos David Rivera Posada, Jairo Alonso O'Byrne, Johan Congote, Diego Restrepo Betancur, Luis Fernando |
| dc.contributor.author.none.fl_str_mv |
Jaramillo Gómez, Carlos David Rivera Posada, Jairo Alonso O'Byrne, Johan Congote, Diego Restrepo Betancur, Luis Fernando |
| description |
ABSTRACT: In the following article the effects of two types of hydroxiapatites on bone synthesis and properties were evaluated. One of them (OseoU) was synthesized at two different temperatures to compare it to a commercial mixture of hydroxiapatite (Osteogen®) commonly used in several surgical procedures in which loss of bone tissue is present. The synthesis was carried out in the laboratories of the Universidad de Antioquia by precipitating the mixture of calcium nitrate and ammonium phosphate. The final products and the commercial hydroxiapatite were characterized by sweeper electronic microscopy (SEM), X ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), and energy dispersed spectrometry (EDS). The properties of osteoconduction and osteointegration were measured according to the capacity of the products to induce the differentiation of local cells into bone forming cells. Such characteristics were evaluated in hydroxiapatite implants in 70 New Zealand breed rabbits distributed in seven groups, ten rabbits in each group, which were evaluated at days 7, 14, 21, 28, 42, 60 and 90 after the surgical procedure. The results demonstrated that the hydroxiapatites synthesized in the laboratories of the Universidad de Antioquia and the commercial hydroxiapatite showed similar characteristics in terms of the crystal structure, chemical composition and absorption properties with slight morphological differences in particle shape and size. Using variance analysis, no meaningful statistical differences were found between the histopathological variables evaluated in the several hydroxiapatite groups (p>0.05), indicating that results obtained with both the OseoU and the commercial hydroxiapatite equally affected bone synthesis and properties. |
| publishDate |
2009 |
| dc.date.issued.none.fl_str_mv |
2009 |
| dc.date.accessioned.none.fl_str_mv |
2017-09-26T16:05:29Z |
| dc.date.available.none.fl_str_mv |
2017-09-26T16:05:29Z |
| dc.type.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.hasversion.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.redcol.spa.fl_str_mv |
https://purl.org/redcol/resource_type/ART |
| dc.type.local.spa.fl_str_mv |
Artículo de investigación |
| format |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| status_str |
publishedVersion |
| dc.identifier.citation.spa.fl_str_mv |
Jaramillo CD, Rivera JA, Echavarría A, O¨byrne J, Congote D, Restrepo LF. Rev. Colomb. Cienc. Pecu. 2009;22(2):117-131 |
| dc.identifier.issn.none.fl_str_mv |
0120-0690 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/10495/8334 |
| dc.identifier.eissn.none.fl_str_mv |
2256-2958 |
| identifier_str_mv |
Jaramillo CD, Rivera JA, Echavarría A, O¨byrne J, Congote D, Restrepo LF. Rev. Colomb. Cienc. Pecu. 2009;22(2):117-131 0120-0690 2256-2958 |
| url |
http://hdl.handle.net/10495/8334 |
| dc.language.iso.spa.fl_str_mv |
spa |
| language |
spa |
| dc.relation.ispartofjournalabbrev.spa.fl_str_mv |
Rev. Colomb. Cienc. Pecu. |
| dc.rights.*.fl_str_mv |
Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO) |
| dc.rights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.uri.*.fl_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/co/ |
| dc.rights.accessrights.spa.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| dc.rights.creativecommons.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| rights_invalid_str_mv |
Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO) https://creativecommons.org/licenses/by-nc-sa/2.5/co/ http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc-sa/4.0/ |
| eu_rights_str_mv |
openAccess |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.publisher.spa.fl_str_mv |
Universidad de Antioquia, Facultad de Ciencias Agrarias |
| dc.publisher.place.spa.fl_str_mv |
Medellín, Colombia |
| institution |
Universidad de Antioquia |
| bitstream.url.fl_str_mv |
https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/1/RestrepoLuis_2009_PropiedadesOsteoconduccionOsteointegracion.pdf https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/2/license_url https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/3/license_text https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/4/license_rdf https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/5/license.txt |
| bitstream.checksum.fl_str_mv |
18f4015037963cdd7106ab1465a93588 4afdbb8c545fd630ea7db775da747b2f d41d8cd98f00b204e9800998ecf8427e d41d8cd98f00b204e9800998ecf8427e 8a4605be74aa9ea9d79846c1fba20a33 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Institucional Universidad de Antioquia |
| repository.mail.fl_str_mv |
andres.perez@udea.edu.co |
| _version_ |
1812173298476253184 |
| spelling |
Jaramillo Gómez, Carlos DavidRivera Posada, Jairo AlonsoO'Byrne, JohanCongote, DiegoRestrepo Betancur, Luis Fernando2017-09-26T16:05:29Z2017-09-26T16:05:29Z2009Jaramillo CD, Rivera JA, Echavarría A, O¨byrne J, Congote D, Restrepo LF. Rev. Colomb. Cienc. Pecu. 2009;22(2):117-1310120-0690http://hdl.handle.net/10495/83342256-2958ABSTRACT: In the following article the effects of two types of hydroxiapatites on bone synthesis and properties were evaluated. One of them (OseoU) was synthesized at two different temperatures to compare it to a commercial mixture of hydroxiapatite (Osteogen®) commonly used in several surgical procedures in which loss of bone tissue is present. The synthesis was carried out in the laboratories of the Universidad de Antioquia by precipitating the mixture of calcium nitrate and ammonium phosphate. The final products and the commercial hydroxiapatite were characterized by sweeper electronic microscopy (SEM), X ray diffraction (XRD), Fourier transformed infrared spectroscopy (FTIR), and energy dispersed spectrometry (EDS). The properties of osteoconduction and osteointegration were measured according to the capacity of the products to induce the differentiation of local cells into bone forming cells. Such characteristics were evaluated in hydroxiapatite implants in 70 New Zealand breed rabbits distributed in seven groups, ten rabbits in each group, which were evaluated at days 7, 14, 21, 28, 42, 60 and 90 after the surgical procedure. The results demonstrated that the hydroxiapatites synthesized in the laboratories of the Universidad de Antioquia and the commercial hydroxiapatite showed similar characteristics in terms of the crystal structure, chemical composition and absorption properties with slight morphological differences in particle shape and size. Using variance analysis, no meaningful statistical differences were found between the histopathological variables evaluated in the several hydroxiapatite groups (p>0.05), indicating that results obtained with both the OseoU and the commercial hydroxiapatite equally affected bone synthesis and properties.RESUMEN: En el presente artículo se evalúan las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible (OseoU), procesada a dos temperaturas diferentes de calcinación (Tipo A y Tipo B), con el propósito de compararlas con un preparado comercial de hidroxiapatita (Osteogen®), utilizado para múltiples procedimientos quirúrgicos en los cuales se involucra la pérdida de tejido óseo. La síntesis se realizó en los laboratorios de la Universidad de Antioquia por el método de precipitación acuosa de la mezcla de nitrato de calcio y de fosfato de amonio. Los productos obtenidos y la hidroxiapatita comercial fueron caracterizados por microscopia electrónica de barrido (SEM), difracción de rayos X (DRX), espectroscopia de infrarrojo transformada de Fourier (FTIR) y espectrometría por energía dispersiva (EDS). Las características de osteoconducción y osteointegración fueron medidas de acuerdo a la capacidad de los productos para inducir la diferenciación de células locales a células formadoras de hueso. Dichas características, se evaluaron en implantes de hidroxiapatita realizados en 70 conejos de la raza Nueva Zelanda distribuidos en siete grupos de 10 animales cada uno, evaluados a los 7, 14, 21, 28, 42, 60 y 90 días de efectuado el procedimiento quirúrgico. Los resultados obtenidos demostraron que el OseoU y el Osteogen®, presentaron características similares en cuanto a la estructura cristalina, la composición química y la adsorción, con apreciables diferencias morfológicas con respecto a la forma de las partículas. Al realizar el análisis de varianza no se encontraron diferencias estadísticas significativas para las variables histopatológicas evaluadas en las dos hidroxiapatitas (p > 0.05), indicando que las hidroxiapatitas sintetizadas en la Universidad de Antioquia (OseoU) tuvieron el mismo resultado que la hidroxiapatita comercial (Osteogen®) en la osteoconducción y la osteointegración del tejido óseo.application/pdfspaUniversidad de Antioquia, Facultad de Ciencias AgrariasMedellín, Colombiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85Atribución-NoComercial-CompartirIgual 2.5 Colombia (CC BY-NC-SA 2.5 CO)info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-sa/4.0/Comparación de las propiedades de osteoconducción y osteointegración de una hidroxiapatita reabsorbible comercial con una hidroxiapatita reabsorbible sintetizadaComparation of osteoconduction and osteointegration properties of a commercial reabsorbable hydroxypatitie with respect to a synthetyzed oneRev. Colomb. Cienc. Pecu.Revista Colombiana de Ciencias Pecuarias117131222ORIGINALRestrepoLuis_2009_PropiedadesOsteoconduccionOsteointegracion.pdfRestrepoLuis_2009_PropiedadesOsteoconduccionOsteointegracion.pdfArtículo de investigaciónapplication/pdf1000633https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/1/RestrepoLuis_2009_PropiedadesOsteoconduccionOsteointegracion.pdf18f4015037963cdd7106ab1465a93588MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://bibliotecadigital.udea.edu.co/bitstream/10495/8334/5/license.txt8a4605be74aa9ea9d79846c1fba20a33MD5510495/8334oai:bibliotecadigital.udea.edu.co:10495/83342021-05-21 20:29:39.645Repositorio Institucional Universidad de Antioquiaandres.perez@udea.edu.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 |